Basic Information

Insect: Drosophila bipectinata
Gene Symbol: RREB1
Assembly: GCA_018153845.1
Location: JAECYF010000108.1:3426149-3432118[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0047 0.35 11.3 0.6 1 21 241 261 241 263 0.96

2 13 0.00027 0.02 15.2 0.2 1 23 273 295 273 295 0.98

3 13 0.11 8.4 6.9 1.1 1 16 301 316 301 318 0.91

4 13 1.7 1.3e+02 3.2 3.7 2 19 544 561 544 563 0.97

5 13 0.0067 0.5 10.8 0.1 1 23 708 730 708 730 0.97

6 13 9.8e-06 0.00074 19.7 0.7 1 23 740 762 740 762 0.99

7 13 0.00066 0.05 13.9 2.0 1 23 768 791 768 791 0.97

8 13 0.0024 0.18 12.2 2.0 1 23 1060 1083 1060 1083 0.95

9 13 6.9e-05 0.0052 17.0 0.3 2 23 1447 1468 1446 1468 0.97

10 13 0.12 8.7 6.9 6.3 1 23 1474 1497 1474 1497 0.97

11 13 1.3 1e+02 3.5 2.1 1 23 1619 1642 1619 1642 0.91

12 13 0.0067 0.5 10.8 0.5 3 23 1709 1729 1707 1729 0.96

13 13 0.0051 0.38 11.2 5.7 1 23 1735 1757 1735 1757 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0047	0.35	11.3	0.6	1	21	241	261	241	263	0.96
2	13	0.00027	0.02	15.2	0.2	1	23	273	295	273	295	0.98
3	13	0.11	8.4	6.9	1.1	1	16	301	316	301	318	0.91
4	13	1.7	1.3e+02	3.2	3.7	2	19	544	561	544	563	0.97
5	13	0.0067	0.5	10.8	0.1	1	23	708	730	708	730	0.97
6	13	9.8e-06	0.00074	19.7	0.7	1	23	740	762	740	762	0.99
7	13	0.00066	0.05	13.9	2.0	1	23	768	791	768	791	0.97
8	13	0.0024	0.18	12.2	2.0	1	23	1060	1083	1060	1083	0.95
9	13	6.9e-05	0.0052	17.0	0.3	2	23	1447	1468	1446	1468	0.97
10	13	0.12	8.7	6.9	6.3	1	23	1474	1497	1474	1497	0.97
11	13	1.3	1e+02	3.5	2.1	1	23	1619	1642	1619	1642	0.91
12	13	0.0067	0.5	10.8	0.5	3	23	1709	1729	1707	1729	0.96
13	13	0.0051	0.38	11.2	5.7	1	23	1735	1757	1735	1757	0.99

Sequence Information

Coding Sequence: ATGCTGGCAGCACCGCAGCAGCAGCAGCACAATACCACCACCAACAACCCAAACACAACTACCACAGAGAACGAGATGGAGCGCCAGAGGCGGGACTCCACCACCTCGGAATCCTCGCTGGAGCACCTGGATTTGGGGCGCACGCCCAAAAAGCTCAGCGCCGTTAGCAGCGGCGGCAGCGGCAGTCTGGTGCTGCAGCCGACGTCAACGCCACACGAAGTAGCGACAGCGACGTCGCGCAAACGTAAGCTCCGCCAGCTCCAACATCATCATCAGGACCTACTCAGTGATGAGGACGAGGAGGAGGACGAAGCGACATCAGGGGTTGGAGCCCGCCCCCACGGTCGTCAAAAGCAGAGGCGCAACGCCTCTGCCTCGGCCAGCATCGTGCTGGACGGCAGCGGCAGCGACGCCAGTTCACTGCGCAAGAAGTTCCGTTTGAATCGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGCCGGATCCGGTGGATCTTCGCCGCAAGGTGGCCTGTGCCTGTCCAGCGGCGAGTCCGGCATTGGGGCGGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCAGTGCCACGCCCCACGAGTTCACCAATCACATTCGGTGCCACAACTACGCCAACGGGGATACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCCGCCTCATCCCTGGACAGACACGTGCTGGTGCACACCGGCGAGCGTCCCTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGGAACATGCACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGCCTCAATCCCGCCCAGCAATCGCTGTCGGGACGGGCGGAGAGCTATGAGAGCGACGCCAGCTGCTCCACAGACGCCTCCAGTGGGCACAGCCGCAGTCGCAGCAGCTCCTCCCTCACCCACAACAACAACAACTCCCAAAAGGCCAACCACAACCACAAGGACATGGAGCTGGACCTGGAGCTGGAGGAGGAGGTGAAGCATCATCAGAACCGTCGCGGGCTCAAGACAACCATAAACAACAATGTCATCGAGAGCGAACACGAGGACGAGGAGGAGGAGCAGGATCACGACGATGTCGATGAGGAGACCGATGTGGCGATGCTGACATCCACTCCCGATGTGGCCACTCTGTTGGCCGGAGCCAGTGGCTCGAGAGCCGCCTCCCGGTCTGTCTCCCCCTCGTCGGCTGCCTCGCCGGCGCTCCTGCTCAGCTGCCCCGCCTGCGGAGCCGGGGACTTCGAGACGCTGCCATCCCTGTGCGACCACCTGGACGCCCGGCACTCGGACATCCCGGCCAAGTGTCGCGATTGTGAGGTGATCTTCGCCAGCCACCGCCAGTTGCAGGCCCATTGCTGTCGCGGCGGAGTAGGACGTCCTGTTGGTGTGGGTCTGCCGCCTCTTATGGGCGCCAGCAGCTCGCCGCTCCACGGTGACGACGATGCCGAGGACGAGGATGACGAGGACGCGGAGCGACGTCGCTTGGAGAAGCAGCGCCTGGCCGACCAGCGCGAGGACTTCTTCCAGCAGCTCTACCTCAAGGGCAAGACCTCCGGCGAACACCCGCCCTCGCCGATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTGCACCAGCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGGCGCGACCAGGAGGAGGAGGCGCAGGATGCCTTCACCTCGGAGTTCCGGCGGATGAAGTTGCGCGGCGAGTTCCCCTGCAAGCTATGCACCGCCGTATTCCCGAATCTGCGTGCCCTCAAGGGCCACAATCGCGTCCACCTGGGCGCCGTGGGTCCGGCCGGGCCCTTCCGCTGCAACATGTGTCCCTACGCCGTCTGCGACAAGGCCGCCCTGGTGCGGCACATGCGCACCCACAACGGTGATCGCCCATACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGAGGCATCTGCGGAACCGGCATGGCAAGACCAGCCGGGAGGAGGTGAAGCGAGCCATCATCTACCATCCGGCGGAGGACGCCGGCTGCGGCGAGGACGGCAAGTCCCGTCTGGGCGAGGATCTGGACCTGAGCTTCCGCTCGATCAGTCCGACTCCCCCGCCACCACCGCCGCCGCTCCCGGAGAGCAGCTCCCAGCTGAAGCACATGCTCCTGGGCGAGAATCAGACAGCCAGTGGAGCTCCCGCTCCCAGCCCCCAGCCTCCGCTGAAGATCCAGGTCAAGAGTCTGGACCAGCTGGTGGACAAGAAGCCCAGCCAGGAGAAGAGCTCGCCCAGCGCCGCCCTGGACTTCAGCATGGACGTGCTGGATCTCAGCAAGAAGCCATCCAGCGGATCGGCGGCCATCACACCGACTCCCACACCGAATCCGGCTCCGCTGGCACCTCCCCCGGGAGTGGCTGGTGCCCCGGACCTGGCCGCCGCTCTGGAGCAGCATCAGTTGCTCCTCGCCCAGCAGCAGCTCTTCGCCGGAGCCGCCGGCGATGCCGCCTCCCAGTATGTCCAGCAATTTTTCCGCAGCCTCATGCTGCAGTCCCAGACTCCGGGCTTCTCGTACCTCTATGGCGCCTTCATGGCCCCGCCGCCGCCGCAGACCAACTCGGAGAAGCCCCCGCCACTGGTGAGCCCGCCCACTCGCGGCTTGAATCCTCTGCCGATGGGCGGTGTGGGCGTGCCAGTGCCTCCGGGCGGACCCGTCAAGATGGTCATCAAAAACGGCGTCCTGATGCCGAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACTCTCCGCAGCAACATGGAGCGCCACGTGAAGCAGCAGCACCCCCAGTTCTATGCCCAGCGCCAGAGAAGCGGCCACCATGTGATGCGAGGACGTGGCGCCTCCAATGCCGCTGCCGCTGCCGCCGCCGCAGCTGCTGCTGCCGGTATGGGTGTTCCCGGCGTGTCATCCGGTGGAGTCGGCTCTGGATCTCATCACCATCCCGGCCACGGTCACGGACACGGACATGCTCCCATCTCGGAGCAGGTGAAGTACGCCATTCTGGCCCAGCAGCTGAAGGCCCACAAGAACACGGATCTGCTGCAGCAAGCCCTGGCCCACGGATCGAGCAGTGTGTCCGGCAATCCTCTCCTGCACTTCGGCTATCCACTGGCCACTCCGCCGCCCAGCTCTGCGCTGCACAACGGCGGTAGCGGGCAGCCGGGAAACGGGGTGCCCATGGTCTCCATGGATGACGATGAGCCCAAGCTGATCATCGACGAGGATGAGAACGACAACGATGTGGAGGAAGTGGAGGACTTCGAGGAAGATGAAGAGGAGGAGGAGGAGGATGAACCGGAGGATGAGCCCGAGATCATTGCCGACGAGGAGCCACTCCCACACGATGAGGAGGAGGACCAGCCGGAGGAGAAGATGGCGGAGCTGGAACTTCCCAAGCCCCTCTTGGAGCAACTGCCCAACGAGGCGGCCCAAAAGACCGCCGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCCCGTGACTACGCCCCCGCCTCCGCCAAAGGACCAGCAACTGGAGCAGCTCTCTCCGCCCGCTCCCAACTCTCTGAAGACCATGATTGCCCAGGCCGAGTCCGTGGCCAAGTCCCTCAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCGCAGGACCTAGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAACAGCGGCACTGAGGACGTCACCAGCAGCTCCTCCGGCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTTGCCCCCAACAGGGTGTCCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCACCTTCTCCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATTCCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGTCGTCAGGAGGCCGAGCGAGAGCGTGAACGCGAACTGGAGCGTGCCCGAGAGCGGGAGCTGGAGCGGGAACGCGAACTAGAGCTGGAGCGCGAGCGTGAGCTGGCCGAGAAGGAGAAGGAGCGCGAACGCCAGCAGCTCATCCAGAAGTTGGCTGCCCAGATGGCTGCCGCCGCCGCCGTCGCTGCCGCTACCCCCGGAGCTCCGGGAGTCGTCGCACCTGGCAGTCTGGATGCCCAGGCTGGCGGAGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTCGCCGACCGGCTGCAGTGCCTCGAGCACATCAAGCAGGCCCATGCCCACGAGTTCGCCCTGCTCCTCGCCAAGGGCGCCATCGAGAACGAGTCCGTGCTGGGCGAGTCGGCCTCGGGCAATCCCAACCAGCCTCCGCCATCTAGCCAGCAGCCGCACTCCGACGATGAGGGCACCAACGGCGTGATCGGTGGAGCCGGAGGACGTGGCAAGTACCCGGACTACAGCAACCGTAAGGTGATCTGCGCCTTCTGTGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGCCGCCACATGCGCACCCACTCCGGGGAGCGTCCGTTCCAGTGCGAGACCTGCCTCCGGAAGTTCACCCTCAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGTGGACGCGCCCACAACGGCGACGCTCCCGGCTCCGACTGCTCCGACGACGAGCAGGTGAGCAGCAGCCCTCCCGGCACCCCGGCCCCACCCACGGCCACCACGGCCGCCACCAATAACAACAACAGCTGCCACACCAACAACAACAACACAGTGAGCGCCAAGCTGGGCCTGAAGCTGCCCAAGCTGCACGAGCTCCTGGACAAGGCGACGGAGTGGCGGGCCAGCCGGCTGACTGGTGAGCACAAGGAGAACCTGGGCGAGGCCACCGCCCCCTCGGGCTCCAGCACAGATCTGATCGGTAACCTCCTCGGGATCAGCGATCAGGGAATCCTCAACAAGCTGCTGTCCTCCGCCGACGAGGCGGCCAAGCTTCTCGGCGTGGACAACAAATAA
Protein Sequence: MLAAPQQQQHNTTTNNPNTTTTENEMERQRRDSTTSESSLEHLDLGRTPKKLSAVSSGGSGSLVLQPTSTPHEVATATSRKRKLRQLQHHHQDLLSDEDEEEDEATSGVGARPHGRQKQRRNASASASIVLDGSGSDASSLRKKFRLNRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGSGGSSPQGGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLNPAQQSLSGRAESYESDASCSTDASSGHSRSRSSSSLTHNNNNSQKANHNHKDMELDLELEEEVKHHQNRRGLKTTINNNVIESEHEDEEEEQDHDDVDEETDVAMLTSTPDVATLLAGASGSRAASRSVSPSSAASPALLLSCPACGAGDFETLPSLCDHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGGVGRPVGVGLPPLMGASSSPLHGDDDAEDEDDEDAERRRLEKQRLADQREDFFQQLYLKGKTSGEHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIIYHPAEDAGCGEDGKSRLGEDLDLSFRSISPTPPPPPPPLPESSSQLKHMLLGENQTASGAPAPSPQPPLKIQVKSLDQLVDKKPSQEKSSPSAALDFSMDVLDLSKKPSSGSAAITPTPTPNPAPLAPPPGVAGAPDLAAALEQHQLLLAQQQLFAGAAGDAASQYVQQFFRSLMLQSQTPGFSYLYGAFMAPPPPQTNSEKPPPLVSPPTRGLNPLPMGGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAGMGVPGVSSGGVGSGSHHHPGHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVSGNPLLHFGYPLATPPPSSALHNGGSGQPGNGVPMVSMDDDEPKLIIDEDENDNDVEEVEDFEEDEEEEEEDEPEDEPEIIADEEPLPHDEEEDQPEEKMAELELPKPLLEQLPNEAAQKTAETILEQAIKAGKPVTTPPPPPKDQQLEQLSPPAPNSLKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERARERELERERELELERERELAEKEKERERQQLIQKLAAQMAAAAAVAAATPGAPGVVAPGSLDAQAGGDLPYKCHLCEGSFADRLQCLEHIKQAHAHEFALLLAKGAIENESVLGESASGNPNQPPPSSQQPHSDDEGTNGVIGGAGGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCETCLRKFTLKHSMLRHMKKHSGRAHNGDAPGSDCSDDEQVSSSPPGTPAPPTATTAATNNNNSCHTNNNNTVSAKLGLKLPKLHELLDKATEWRASRLTGEHKENLGEATAPSGSSTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504177;
90% Identity: iTF_00580189;
80% Identity: -