Basic Information

Insect: Drosophila bipectinata
Gene Symbol: zfh1
Assembly: GCA_018153845.1
Location: JAECYF010000041.1:4126227-4145957[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0011 0.083 13.2 3.2 3 23 74 95 72 95 0.95

2 9 0.00078 0.058 13.7 0.1 1 23 286 308 286 308 0.97

3 9 8.6e-05 0.0065 16.7 1.7 2 23 322 343 321 343 0.97

4 9 4.2e-06 0.00032 20.9 6.3 1 23 352 374 352 374 0.99

5 9 0.00025 0.019 15.3 1.2 3 21 382 400 380 401 0.94

6 9 0.0058 0.43 11.0 0.7 2 21 620 639 619 640 0.92

7 9 2.9e-05 0.0022 18.2 0.5 1 23 962 984 962 984 0.95

8 9 4.2e-05 0.0031 17.7 7.4 1 23 990 1012 990 1012 0.98

9 9 0.0021 0.16 12.4 4.3 1 21 1018 1038 1018 1039 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0011	0.083	13.2	3.2	3	23	74	95	72	95	0.95
2	9	0.00078	0.058	13.7	0.1	1	23	286	308	286	308	0.97
3	9	8.6e-05	0.0065	16.7	1.7	2	23	322	343	321	343	0.97
4	9	4.2e-06	0.00032	20.9	6.3	1	23	352	374	352	374	0.99
5	9	0.00025	0.019	15.3	1.2	3	21	382	400	380	401	0.94
6	9	0.0058	0.43	11.0	0.7	2	21	620	639	619	640	0.92
7	9	2.9e-05	0.0022	18.2	0.5	1	23	962	984	962	984	0.95
8	9	4.2e-05	0.0031	17.7	7.4	1	23	990	1012	990	1012	0.98
9	9	0.0021	0.16	12.4	4.3	1	21	1018	1038	1018	1039	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCGTCGTCTTCACGTTTCGGCCAAGAGGATACCATCATTCAGCAGAGCATGCCATCCACAGCCTTCACCATGCAGTTTCCCGCGCTGGCCTCCAGTCTGCACCACCACAGCCACAACCAATCGCCGCACCACAGCAAGCCCGGACCCCAGGATGGCCAGCACGTGCAACCAGGTGCCGCAGCCGACGATTTTCTGGTCAACTGCACCCAGTGCCACAAGCGATTCACAGACTTCCACTCTCTGAGTGAACATATTGCCAGCGAGCATCCCCACGACAAGCTGAACTTGGGAGCCGCGCAACCGGAAAGCGAACCGGAAGATGAGCAGAGCAACTTGAGCAGCGGAAGTCGGCGGTATCTGAAATCGCCAACCACTAGTATTGGTAACACGAATGCCAACTCCAGCAACAACAACAACAACAGTGATCTGGCCAAGAACCACAACAATACCAACAAACGGTCGCCCATGTGCTCCCCCATTTCCAGCGTGGGAATGGGCGGTGTGGGAGCAGGTCCCCCCAGCGATCTGTTCGCCCACCTCTCGCATGCCACGCCCCAGCTGCCCGCCCTGCAAGCCCAGTTCATGGCCGCCGCCGCTCTGGCCATGCAATCCGCCCGCTCCGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCCGCCTACGATCTGGATCTGAGTGCACCACGATCCACCTCCAGTCCCGGCTCCACCACCGGGGACCTCAGCGGGGCCTACCCCTGCATGCAGTGCACCGCCGCCTTTGCCTCCAGGGAGCAGCTGGAGCAGCACCAACTCCTCCACTCGCCTTGCGGCCAGCCAGCCCCCCAGAATGTGTCACAGACCTGCCGTATCTGCCACAAGGCCTTTGCCAACGTCTACCGACTCCAGAGGCACATGATCAGTCATGACGAGAGCGCCCTTCTGCGGAAATTCAAGTGCAAGGAGTGCGACAAGGCCTTCAAGTTCAAGCATCACCTCAAGGAGCATGTGCGGATCCACTCCGGCGAGAAGCCCTTCGGCTGTGACAACTGCGGCAAGCGGTTCTCCCACTCGGGAAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGCCTCAAGCTGAACAACAACCGGGCTCTGCTAAAGAGATTGGAAAAGGGTCCGGGATCGGGCTCGTCGTCACGCCTCTCGCCCTCGGACCAGGCCAAAGGCAAGCTCCAGGAGCAACCGCCCCTGCCGGGTCTGCCGAACCCCATGATTTACTTTGCCAGCGATGCTCAGAACCAGGCGGCCAACAATGGACCCGCGTCCTTCCCGAACTTCCACCACACAAACTACATGAATGCTGCCCTACTGGCCTTTCCGAATCCCTTCATGGCCGCCCTGGATCCTCGAATGCATCCCTACAGCATTCAGCGATTGCTTCAATTGACGGCTGCAGGCCAGCAACAAAGGGAGGAGGAACAGCGGGAGCAGGAGATCCAAGAGGAGGAGACACCCGAGGAACCCAAGCTGGTGATGGATATCGATGAGCCGGAGGTTAAGGAACGGGCTGCCACTCCTCAAGAGCATGAGGAGGTCGCTCCCATTAAGCGGGAGACCAGCCGCGAAGCATCTCCTGCTCCGGAAAGCAATCCCCCATCGCCGCAGGTCATCAAACAGGAACCGGAGGTACAACCGCTAGAACCAGAGCCCCAAGTCATGGAGGAAGAACCCATTCCAGCTCCAGAACAGCCTGCCGATTTGCGCTGCAGTCGCTGCTCCAAGCAATTCAACCATCCCACGGAACTGGTGCAGCACGAGAAGGTTCTTTGTGGCCTCATCAAGGAGGAGATGGAGCAACATTTCCAGCAACAACAACAGCAGCAGCAGCAGAGCCTACAAGCCCCAGCCTTCGTCCTGCCGTCCGCCAGCGAGGAAGATGAGGAAGAAGAGGAGGAGGAGCCCAGGAACCAGGAGACTGGCGAGCGAAAGGTCCGCGTGCGCACGGCCATAAACGAGGAGCAGCAGCAGCAACTGAAGCAGCACTACTCCCTGAACTCCCGACCCAGCAGGGATGAGTTCCGCCTGATAGCGGCCAGGTTGCAGCTGGATCCCCGAGTGGTGCAGGTGTGGTTCCAAAACAATCGCTCCCGAGAGCGCAAGATGCAGAGTTTCCAGAGCAACCAAAGCGCCACAGTCCCTCCCACAACCGAGTCCCAGTCCAGTGCATCTCGTGAAGACCAACCTCTGGACCTGTCTGTTAAGCGCGATCCTCTGACCCCCAAGAGTGAGAGCTCCCCTACTTATATGCCTCCGCAAACGGCCGAAGCTCTCAACCCGGAAGCCATCAACCTGAGCCGGAAGTTCTCCAGCTCAGCTTCGATGTCACCGGCTTCGATTTCACCCTCATCCGCGGCAGCTTTGTATTTTGGAGCCGCACCGCCGCCGTCGCCGCCCAACAGCCAACTGGAGGCCAATACTCCTCGCAATAACCAGGCCTTTCCGGGACTTCCTGCCTACATGCTTCCCATGCAGCGGCTGCCCATGGAGGCGCTTTTCCAGATGCGACCAGGTGGCGAGTATGCACCGAACCATCCCCTGATGAACAGTATTAAGCTGCCCGACTACCGAGGCACCAGCCTCAGTCCGGGAGGATCGGAGAAGCGCTCGTGGCGGGACGATGACTCGCGCATTTCGCACGAGGACGACTTCTCTGGTGGACTGCTGCCCCCCAAGCAGAGGAGGGGCAAGGCGGAGACCCATGGACACGCCGGCGATCCGGACTTGCCATATGTCTGCGACCAGTGCGAGAAGGCTTTCGCCAAGCAGAGTTCCCTAGCGAGGCACAAATACGAGCATTCCGGTCAACGACCCTACCAGTGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGCCTCCACAGTGGGGAGAAGCCCTTCCAATGCTCCAAGTGCCTGAAACGGTTCTCGCACTCGGGCAGCTACAGCCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSSRFGQEDTIIQQSMPSTAFTMQFPALASSLHHHSHNQSPHHSKPGPQDGQHVQPGAAADDFLVNCTQCHKRFTDFHSLSEHIASEHPHDKLNLGAAQPESEPEDEQSNLSSGSRRYLKSPTTSIGNTNANSSNNNNNSDLAKNHNNTNKRSPMCSPISSVGMGGVGAGPPSDLFAHLSHATPQLPALQAQFMAAAALAMQSARSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTAAFASREQLEQHQLLHSPCGQPAPQNVSQTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKGPGSGSSSRLSPSDQAKGKLQEQPPLPGLPNPMIYFASDAQNQAANNGPASFPNFHHTNYMNAALLAFPNPFMAALDPRMHPYSIQRLLQLTAAGQQQREEEQREQEIQEEETPEEPKLVMDIDEPEVKERAATPQEHEEVAPIKRETSREASPAPESNPPSPQVIKQEPEVQPLEPEPQVMEEEPIPAPEQPADLRCSRCSKQFNHPTELVQHEKVLCGLIKEEMEQHFQQQQQQQQQSLQAPAFVLPSASEEDEEEEEEEPRNQETGERKVRVRTAINEEQQQQLKQHYSLNSRPSRDEFRLIAARLQLDPRVVQVWFQNNRSRERKMQSFQSNQSATVPPTTESQSSASREDQPLDLSVKRDPLTPKSESSPTYMPPQTAEALNPEAINLSRKFSSSASMSPASISPSSAAALYFGAAPPPSPPNSQLEANTPRNNQAFPGLPAYMLPMQRLPMEALFQMRPGGEYAPNHPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDFSGGLLPPKQRRGKAETHGHAGDPDLPYVCDQCEKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615732;
90% Identity: iTF_00476115;
80% Identity: iTF_00487903;