Basic Information

Insect: Drosophila biarmipes
Gene Symbol: RREB1
Assembly: GCA_018148935.1
Location: JAECYG010000274.1:9380295-9386959[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.031 1.9 8.9 0.8 1 21 240 260 240 262 0.93

2 11 0.0026 0.16 12.3 0.1 1 21 272 292 272 293 0.94

3 11 1.8 1.1e+02 3.3 3.7 2 19 451 468 451 470 0.97

4 11 0.0077 0.46 10.8 0.1 1 23 610 632 610 632 0.97

5 11 1.1e-05 0.00064 19.8 0.7 1 23 642 664 642 664 0.99

6 11 0.00072 0.043 14.0 2.0 1 23 670 693 670 693 0.97

7 11 0.0026 0.15 12.3 2.0 1 23 967 990 967 990 0.95

8 11 7.5e-05 0.0045 17.1 0.3 2 23 1358 1379 1357 1379 0.97

9 11 0.13 7.5 7.0 6.3 1 23 1385 1408 1385 1408 0.97

10 11 0.0073 0.44 10.9 0.5 3 23 1622 1642 1620 1642 0.96

11 11 0.0012 0.072 13.3 4.8 1 23 1648 1670 1648 1670 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.031	1.9	8.9	0.8	1	21	240	260	240	262	0.93
2	11	0.0026	0.16	12.3	0.1	1	21	272	292	272	293	0.94
3	11	1.8	1.1e+02	3.3	3.7	2	19	451	468	451	470	0.97
4	11	0.0077	0.46	10.8	0.1	1	23	610	632	610	632	0.97
5	11	1.1e-05	0.00064	19.8	0.7	1	23	642	664	642	664	0.99
6	11	0.00072	0.043	14.0	2.0	1	23	670	693	670	693	0.97
7	11	0.0026	0.15	12.3	2.0	1	23	967	990	967	990	0.95
8	11	7.5e-05	0.0045	17.1	0.3	2	23	1358	1379	1357	1379	0.97
9	11	0.13	7.5	7.0	6.3	1	23	1385	1408	1385	1408	0.97
10	11	0.0073	0.44	10.9	0.5	3	23	1622	1642	1620	1642	0.96
11	11	0.0012	0.072	13.3	4.8	1	23	1648	1670	1648	1670	0.99

Sequence Information

Coding Sequence: ATGCTCGCCGCACAGCAACAGCAACAGCAGCAGCACAACAGCAACAGCACAGCGGAGGCCGAGATGGAGCGCCAGCGCCGGGACTCCACCACCTCAGAGTCCTCGCTGGAGCACCTGGACTTGGGACGAACGCCCAAGAAGCTCGGCGGCAATGCTGGCTCCGCACAGACCACATCCACGCCCCACGAACTGACGACTGTCACATCGCGCAAGCGCAAACTCCGCCAGCTGCAGCACCATCAGCAGCTGACCCATCTCCACCAGCAGCCGGAGGCGATGAGCGACGAGGACGAGGAGGAGGATGAGCACGAGGCCGAGGAGCACCCGGCCACGGGTGCCCGCAATCTGGGGCGGCACAAGCAGCGCCGCAGCACCCAGGCCTCCATTGTGGTGGACTACAGCAGTGGCGACGCCAGCTCCCTGCGCAAGAAGTTCCGGCTCAACCGCTCGGCGGCCAGTCTCTCGGAATCGGGATTCGTGGATGCCAGCAGCACGGCCCACAGTGGCTATCTGGGCAACAGCAGTGGCAGTGCCACCAACACCACCGCAAACACCACCGCCAGTGGTGCGGCTGTGGTTCCGTCGGCGGTGGGAGGAGCCACTGCCTCCAGCAGCAGCAGCGGCAGCAGCAGTGGCGGCTCCGGCGGCTCCTCGCCGCAGGGCCCGAGCCTCTCCAGCGGCGAGTCGGGCATCGGAGCCGGCGACGAGCACATGAAGTACCTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCGCACGAGTTCACCAACCACATCCGGTGCCACAACTACGCCAACGGCGACACGGAGAACTTCACCTGCCGCATTTGCTCCAAGGTGCTGTCCTCGGCCTCATCCCTGGACAGGCACGTGCTGAGCTACGAGAGCGACGCCAGCTGCTCCACGGACGTGTCCAGCGGCCACAGCCACAGCCACTCGCACAGCCGCAGCAGCAGCTCCCTGAACAACAACAACAACGCGCACAAGGCTAACAACAACCTGAAGGACCTGGAGGCGGACCAGGTGGAGGAGCCGGAGGCGGAGGGCAAGCAGCGCCGCCTGAAGACGACCATCAACAACAACATCATCGACAGCGGGCACCAGGAGGAGCTCGAGGAGGATGAGGAGGAGGCCGACGACACGGACGTGGCCATGCTGACCAGCACACCGGATGTGGCCACCCTGCTGGCCGGAGCCAGTGCATCCGGGGCGGCCTCCCGCTCGCCCTCGCCCTCGCCATCCGCCTCGCCGTCGCTGCTCCTGAGCTGTCCCGCCTGCGGAGCCTCCGACTTCGAGACCCTGCCCGCCCTGTGTGCCCACCTGGATGCGCGGCACTCGGACATACCGGCCAAGTGCCGGGATTGCGAGGTGATCTTCGCCAGCCATCGCCAGCTGCAGGCCCACTGCTGTCGCGGATCGTCGGGCATCCTGCCGCCGCTCCTGGGAGCCAGCAGCTCACCGCTGCACCAGGAGGAGGATCAGGAGAACGAGGAGGACGAGGAGCTGGAGCGCAAGGTGGGAGTGCCCAGCCAGAGCGAGGACTTCTTCCACCAGCTGTATCTGAAGCAGAAGACGGCCGGCGGAGCCAGCGGTGCCATCTCCCATCCGCCCTCGCCCATCAAGCACGAGCCGGCGGACAGCAAGGATCTGGCCGATATCCAGAGCATCCTCAACATGACCAGCTCCAGTTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCGAGCTCCAGCCAGTACAGTCTGGATGGCCGGGACCAGGAGGAGGAGGCCCAGGATGCCTTCACCTCGGAGTTCCGCCGCATGAAGTTGCGCGGCGAGTTCCCCTGCAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCATCTGGGCTCCGTGGGTCCCGCCGGGCCCTTCCGCTGCAACATGTGCCCCTATGCCGTGTGCGACAAGGCCGCCCTGGTGCGCCACATGCGCACCCACAACGGAGATCGCCCCTACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCCAACTGCGAGCGTCACCTGAGGAACCGCCACGGGAAGACCAGCCGGGACGAGGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGATGCCGGCTGCGAGGACAGCAAGTCGCGCATGGGCGAGGATCTGGCCGATCTCAGCTTCCGTTCCATCAGTCCCACGCCCCCGCCGGCGCCCGTCATCATCGGTGGCGAGAGCAGCAGCTCCCAGCTGAAGCACATGCTGCTGGGCGAGAGCCACCTGGCTCCGGTGGCCCAGCCGCCGCTGAAGATCCAGGTGAAGAGTCTCGACCAGCTGGTGGACAAGAAGCCAGCCAAGCCAGTGGCCCCAGCCCCACAGCAGCAGCTCCAGGAGAAGATGGGCGCCGCCCTGGACTTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACGGGAGGAGCAGCAGCGCTGACCCCCTCGGTCACACCCACTCCGCCCACGCCCGCCCCCGGAGTTGTGCCACCGGGCGTTGGCGCACCCGCCGACCTGGCCGCCGCCCTGGAGCAGCAGCAATTGCTGCTGGCCCAGCAGCAGCTGTTCGGCGCTGGCGGAGATGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCATGTTCCAGTTCCAGTCGCAGACGCCGGGATTCCCCTTCTTTCCCTTCATGGCGCCACCGCCGCCGCAGGCCAATCCCGAGAAGCCGCCGCTGGTGAGTCCGCCCAGCCGCATGAATCCCCTGCCCGTGGGCGTGGGCGTGGGTGTGCCGGTGCCACCCGGTGGCCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAGCGTCGCTATCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCGGCGAGATTCACCTTGCGCTCGAACATGGAGCGCCACGTGAAGCAGCAGCATCCGCAGTTCTATGCCCAGCGCCAGCGGAGCGGCCACCATGTGATGCGGGGCAGGGGAGCCTCCGGAGCAGCAGCCGCTGCTGCCGCCGCCGCCGCCGCTGCAGCTGCCATGGGCCCGGGATCCGGCTCCGCCGTCGGCTCCAATCACCACCATAGCCACGGCCATGGCTCCCATGGACATGCCCCCATCTCGGAGCAGGTCAAGTACGCCATTCTCGCCCAGCAACTGAAGGCCCACAAGAACACCGATCTGCTGCAGCAGGCTCTGGCCCATGGCTCCAGCAGTGTGGCCGGCAATCCCCTCCTGCACTTCGGCTACCCCCTGGCCACGCCCAGTCCCCTGCACAATGGCTCCGGACCGGGCAATGGCCAGGCCATCGCCATGGACGACGATGAGCCCAAGCTGGTCATCGATGAGGATGACAACGAGCACGATGCGGAGGAGCCCGAGGAGGTGGAGGACTTCGAGGAGGATGAGGACGAGGAGGAGATGGACGAGCCGGAGGAGGAGCCCGAGCTGATCCCCGATGAGCAGCCAGCCGAGGAGGCGGAGGAGGAGCAGGACGAGCAGGAGGAGCCGGAGCTGCCCAAGCCGCTGGAGCAGCTGTCCCTGGTGGCGCCGGCCAATGAGGCGGCCCAGAAGATGGCCGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCCGACGAGTCCGCCGCCCCAGGAGAATGCCCAGCCGGTGGACGCCAAGGTGGTGCCCACCATGCAGGAGCCAGCCGTGACCGGCAGTGCCAGCAGCCTGAAGACCATGATTGCCCAGGCCGAGTCGGTGGGCAAGTCCCTGAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTATTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGTGCCAGCGAGAGCAACAACAGCGGCACCGAGGACGTGACCAGCAGCAGCTCCAGCAGCGAGCCCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGGATGTTCCCCTGGAGCAGCTCGCTGCGCAGGCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGTTGTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCGGCCATGTCGGTGTATGTGCCCACCGAGGACGTGAGCGAGCCCATCCCGGTGCCCAAGTCCGTGGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGGCAGGAGGCGGAGCGCGAGAAGGAGCGCGAGCTGGAGCGGGAGCGGGAGCTGGAGCGGGAGCGCGAGCTGGAGCGCGAGAAGGAGCGTGAGCTGGAGAAGGAGCGGGAGCGCCAGCAGCTCATCCAAAAGCTGGCGGCCCAAATGAATGCCGCTGCCAATGCCGCTGCAGCCGCCGCCGCCGCCGCCGCTGCAGCTGCCTCTTCGGTGGGCAATGGCAATGGTGGAGCCCCAAATGGCCCACTGGGCGATGCCCTCGCTGGCGGAGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTTGGCGAGCGCCTGCAGTGCCTGGAGCACATCAAGCAGGCGCATGCCCACGAGTTCGCCCTGCTTCTGGCCAAGGGCGCCATCGAGAACGAGTCACTGGAGGGGGCCAATCCCCAGCAGCAGCAGCAGCAGATGTCCCAGCAGGCGGCAGTGCACTCGGACGACGAGGCTCCCAATGGCAACGGGAGTCGCGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGCCGCCACATGCGCACCCACTCGGGCGAGCGGCCCTTCCAGTGTGACATCTGCCTGAGGAAGTTCACCCTCAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCGCCCACAACGGGGACACGCCCGGCTCCGATTGCTCCGACGATGAGCAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAGCGAGTGGCGGGCCAGCCGGCTGGGCGAGCACAAGGAGAACATGGGCGAGGCCACGCCCTCGGCGGCCGCCGTCGCCGGCTCGGATCTGATTGGCAACCTGCTGGGCATCAGCGACCAGGGCATCCTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTCCTGGGCGTGGACAACAAGTAG
Protein Sequence: MLAAQQQQQQQHNSNSTAEAEMERQRRDSTTSESSLEHLDLGRTPKKLGGNAGSAQTTSTPHELTTVTSRKRKLRQLQHHQQLTHLHQQPEAMSDEDEEEDEHEAEEHPATGARNLGRHKQRRSTQASIVVDYSSGDASSLRKKFRLNRSAASLSESGFVDASSTAHSGYLGNSSGSATNTTANTTASGAAVVPSAVGGATASSSSSGSSSGGSGGSSPQGPSLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLSYESDASCSTDVSSGHSHSHSHSRSSSSLNNNNNAHKANNNLKDLEADQVEEPEAEGKQRRLKTTINNNIIDSGHQEELEEDEEEADDTDVAMLTSTPDVATLLAGASASGAASRSPSPSPSASPSLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGSSGILPPLLGASSSPLHQEEDQENEEDEELERKVGVPSQSEDFFHQLYLKQKTAGGASGAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGSVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDAGCEDSKSRMGEDLADLSFRSISPTPPPAPVIIGGESSSSQLKHMLLGESHLAPVAQPPLKIQVKSLDQLVDKKPAKPVAPAPQQQLQEKMGAALDFSMDVLDLSKKPTGGAAALTPSVTPTPPTPAPGVVPPGVGAPADLAAALEQQQLLLAQQQLFGAGGDAASQYMQQLFRMFQFQSQTPGFPFFPFMAPPPPQANPEKPPLVSPPSRMNPLPVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASGAAAAAAAAAAAAAAMGPGSGSAVGSNHHHSHGHGSHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLATPSPLHNGSGPGNGQAIAMDDDEPKLVIDEDDNEHDAEEPEEVEDFEEDEDEEEMDEPEEEPELIPDEQPAEEAEEEQDEQEEPELPKPLEQLSLVAPANEAAQKMAETILEQAIKAGKPTSPPPQENAQPVDAKVVPTMQEPAVTGSASSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKERELERERELERERELEREKERELEKERERQQLIQKLAAQMNAAANAAAAAAAAAAAAASSVGNGNGGAPNGPLGDALAGGDLPYKCHLCEGSFGERLQCLEHIKQAHAHEFALLLAKGAIENESLEGANPQQQQQQMSQQAAVHSDDEAPNGNGSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQLPKLHELLDKASEWRASRLGEHKENMGEATPSAAAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605068;
90% Identity: -
80% Identity: -