Basic Information

Insect: Drosophila biarmipes
Gene Symbol: zfh1
Assembly: GCA_018148935.1
Location: JAECYG010000101.1:24849540-24853687[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.6e-05 0.0022 18.1 1.1 1 23 140 162 140 162 0.97

2 15 0.075 4.5 7.7 0.1 3 17 170 184 168 185 0.89

3 15 0.00014 0.0086 16.3 0.2 1 23 254 276 254 276 0.98

4 15 0.00057 0.034 14.4 0.8 1 23 282 304 282 304 0.98

5 15 3.5e-05 0.0021 18.2 2.3 1 23 335 357 335 357 0.97

6 15 0.0018 0.11 12.8 0.1 1 23 387 409 387 409 0.94

7 15 0.0098 0.58 10.5 1.3 1 23 415 438 415 438 0.97

8 15 0.024 1.4 9.3 0.4 3 19 447 463 446 464 0.95

9 15 0.00014 0.0085 16.3 5.6 1 23 473 495 473 495 0.97

10 15 0.037 2.2 8.7 1.2 2 23 501 522 500 522 0.96

11 15 8.3e-06 0.0005 20.1 1.0 1 23 531 553 531 553 0.98

12 15 0.00094 0.056 13.7 0.1 3 23 561 581 559 581 0.97

13 15 5e-05 0.003 17.7 0.5 1 23 587 609 587 610 0.95

14 15 0.033 2 8.8 0.3 1 23 620 642 620 642 0.97

15 15 0.005 0.3 11.4 0.2 1 23 1168 1190 1168 1190 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.6e-05	0.0022	18.1	1.1	1	23	140	162	140	162	0.97
2	15	0.075	4.5	7.7	0.1	3	17	170	184	168	185	0.89
3	15	0.00014	0.0086	16.3	0.2	1	23	254	276	254	276	0.98
4	15	0.00057	0.034	14.4	0.8	1	23	282	304	282	304	0.98
5	15	3.5e-05	0.0021	18.2	2.3	1	23	335	357	335	357	0.97
6	15	0.0018	0.11	12.8	0.1	1	23	387	409	387	409	0.94
7	15	0.0098	0.58	10.5	1.3	1	23	415	438	415	438	0.97
8	15	0.024	1.4	9.3	0.4	3	19	447	463	446	464	0.95
9	15	0.00014	0.0085	16.3	5.6	1	23	473	495	473	495	0.97
10	15	0.037	2.2	8.7	1.2	2	23	501	522	500	522	0.96
11	15	8.3e-06	0.0005	20.1	1.0	1	23	531	553	531	553	0.98
12	15	0.00094	0.056	13.7	0.1	3	23	561	581	559	581	0.97
13	15	5e-05	0.003	17.7	0.5	1	23	587	609	587	610	0.95
14	15	0.033	2	8.8	0.3	1	23	620	642	620	642	0.97
15	15	0.005	0.3	11.4	0.2	1	23	1168	1190	1168	1190	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGCGATATGGCGGAATCCAGTGGATACAGCACCACGTCTCCGCGGGCGACTCCTCCGAGGTGGACATCCTGGAGTCGGACGGCGGAGCGGTGCCAACGGGCGAGGATCTGGACCATATGGCAGCCGAGAATCTGATCTTCATGGCGCGCGACGGCCAGCTGAGCGAGATAATGGCGGCCAACGAAGCGGGCGGCACAGTCCTGGTCACCGCCGATGGCACCACAGTGGCCTACGCGGAGTCCTTCGACGACGAGGCTCAAGTGGTCACCGAGGAGGTCATCACGGACGACTGGGTGCAGCACCAGGGCGCCGAGCGTGTGGAAATAGCCGCCGATCAGATAGCTGGGATCAGTAGCTCCCAGGAACTGCTGGACATGGAGCAGGACGAGTATACTGCGCTGAGGCCCTATCCCTGCGACTTCTGCAGCCGTCGCTTTCGAAAGAAGGCCACGTTGAACAACCACATGCTGGCCCACCAGAATGATCGACCGCATCTCTGCAAGCTGTGTGGAGCGCGCTTCTCACGCCGGGCCGAGCTCATCACAGCTCCTTCTCGGGGCAGAATCAGTCGACTAAAGCCGAAGGAGGAGAGCAGCCAATTCATCGTGATTTCCGAAAAGCCAGCGGTCGCAGAATTGAGGCAGTACATGGAGGCTGAGGCGTCTCAGCCTGTGGTCACCACGTCGCAGCCCATCGCCGTCGACCCGCCTCCTCAGCCAAACTTCCCGGTGCTGGACGACAGCAAACCCTTTGTTTGCCAGCAGTGTGGATTGGCCTTTGCGCGGGAAAAGGCGCTCATCTCACATACGAAGAACCACCGCGTGGACTCGCCCTTCGAGTGCAACCAGTGCCAGGAGATGTTCTGGGACAACAACAGCCTGCAGGAGCACCAGAAGACGCATCAGTTCGAGGAGAGTAACTCGGAGTACGATCCGGCCTCGGCAGAGGATAGTGCCAGCGAGTCTGAGAACGAGGAGCAGCTGTACGGCGAGTTCTATTGCTACGATTGCGGGATCTCTTTCCATCGCCAGGACCTGCTGCGACGCCATGCCAAGCTGCACAACAAGCAAACGGATCAGGTGGTCGGCGAAAGCAATTCCGATGTCACTGCTGGCGGTGATGTAGAGGTTGCCAAAGATTCAGCGGGTCACAGTTGTAGCACATGCGGGAAGACCTTCCCCAGCGCTTTGGAGATGCTGGCCCATGCCGAGATCCATGCTCGGTTCCCGCCTTTCAAATGCGTTCTATGCGGAATAAGCTTTTACGAGGAGCAGGCCATCAAGCGGCACCTGCACACCCGCCACCCCACGGAACTGAAGGCCAACTCCTGCGTGCTGTGCGGCAAGGAGTGCCGTGATCGCAAGGCTCTGATTAAGCACGCATGGGACCATTCGCGCGAGAAGTGCCACTCGTGCTCCAAATGCGGCAAGAACTTCCACAACAAGGCGCGCCTGAAGCGGCACATGGCCTCGCATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAATTTCCCGACGGACGGACGCTCTCCAACCACCGGCACTCGCACAGCACCACCTCGCCGGGCAAGCTGTTTCCGTGCCACGAGTGCGGCAAGACCTTTGGATCGCGTAGCTCCCAGCAGATCCACGTTCGCATCCACACTGGGGAGCGTCCGTATGGCTGTCGCTACTGCTGGAAGGCCTTCGCTGATGGTGGCACGCTGCGCAAGCATGAGCGGATACACACGGGCGAGAAGCCCTACGCCTGTTCCGTCTGTCCGCGTGCGTTTAATCAACGGGTGGTGCTGCGGGAACACATCCGCTCTCATCATTCTGGTCTGGATGTAGCGCGTAATACGTACCATTGCACGGTCTGCTCCGAGGACCTGGCCTCGTCCAATGACCTCATCCAGCACCTCATCCAACACAGTGACTCAAACACCGCCAAACAGCGGCAACCCATTACGGGACCGCGCAAGTACAAGCGTCGACGTAAACTGCAGCCCTTCGAGATTGCTCACATGCGTGCAGAGCACAAGGACGCCAACGGCGAAGAGGAGGAGGCCACAGGAGATGGCGAAGCCGAGGAGTACGCCAGTGACATAGACCTTTGCGACTTTGATGTCGAGAATGTGGACGATCTCTTTGACATGGCCGAGTCGCCCAAGAAGGAGAAGCGAAAGAGGGGATCGACAGCCCCGAAGGCCGATTCTAAGCCCGCGACCAATGGCAAAGCAGTAAAACCTGCCCAGGAAAAGAGCAAAGCCAAGCCAAGATATGACTCCACCAGCAGTCAGCAATCGGATCGAATCTGGGAGGAGAAGTTTCTGCAGGACAGCCAGGTGTCTCTCTTTCAAATCGATTCCCTGGTGGTGGTCAATGATACTCATCTGCAGCCCGCCACCCCCACTGGTTTAGCCGCACCCAACACAAGATCTGGGGCCAAGCAGCAAGGAAAACTTCAGGCAAAGCCTGGAGAAGGAGCTGGAAGTTTAAACCACTCTGCTGCCGCATCTGTTTCCACATCGTCCGCCTCAACTTCTAGCAGTCGCAGCAGGAAGAAGGCAGCAACCAACAAGACTGCTAACAAAGCTCCACCTGTCAGTAATTCGCGACCCCGAATGATTCACACTGAAAAGGCCAAGATGACGAGGGGCGCTAGCGGAGAATCCTCTGGCAGTGCGACGAAGAAGTCTCGCTCCAAGACCTACATTAGTCGCACGGAGACCAGTAATTTGGGCCTGGACAAGACCCGCAGCAGTGCCTCAAACATTGTCGATGACTACGAGATCATTTCTCCAGCCACTCATCCACCAAATCAAATAAGCTCCAGTCCCTTGCACATAAAACAGGAGCAGGAGCAACAGCAGCGGGTGCAGCTTATGTACGATGATAATCTGCTGATAGATTCGGCCTTGCTTAGGGAGAAGACGTACGATAAGTTCAACCCCAGCATGGTTAACGATCTGGACGATATTTTGCGCTCGCCACTAAAACACGAGAGGAATTCCCGTCTACGCTTTACCAGTGAATCCTCGACCACGCCACAGTTTTTGCCCGAGGAAGAGCAAAATCTGATCAAGATCGAACCAACGTCCCCGGACTTGCGGGAGATGGTGGAGAGCCAGCAGAGGGTCACGGCTCATGGTGGGAGCACTCCGTCGTCCTCCTCTGCCAGGACTTCCAGACATCTGCGTCAGATCACTGCCAATGGAACAAGGGCAGGGAGCAAAAGAACGGCCGGAGGCGTGGCCAGCAAATCTTCACCATCTCCGGGAGTGGCGGCCAAAAAAGCGAACACTGCCACCAAGGTCAGCAGTAGCTCATCCTCTTACCTCGGTTACGGGGTAGATTCTTACAACGTGAACGTACCTGCCAGCGCCAACAATGCCGATGTAGGCAGTGGATTCTTTTCCATCTCGGAGGTCGTGTCCGCAGCCGATGCCGCAGATGCGGCTGCCAAGGCGGCGGCAGCTGGTAAAACGGAGCGGAAAAGCCGCAGTTTCGAGTGCGAAATGTGCTCGGCCATCTTTTATGATCGAGCCCAACTGCTGGAACATGTACACATCCACATTTAG
Protein Sequence: MNNQRYGGIQWIQHHVSAGDSSEVDILESDGGAVPTGEDLDHMAAENLIFMARDGQLSEIMAANEAGGTVLVTADGTTVAYAESFDDEAQVVTEEVITDDWVQHQGAERVEIAADQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKATLNNHMLAHQNDRPHLCKLCGARFSRRAELITAPSRGRISRLKPKEESSQFIVISEKPAVAELRQYMEAEASQPVVTTSQPIAVDPPPQPNFPVLDDSKPFVCQQCGLAFAREKALISHTKNHRVDSPFECNQCQEMFWDNNSLQEHQKTHQFEESNSEYDPASAEDSASESENEEQLYGEFYCYDCGISFHRQDLLRRHAKLHNKQTDQVVGESNSDVTAGGDVEVAKDSAGHSCSTCGKTFPSALEMLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPTELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPFEIAHMRAEHKDANGEEEEATGDGEAEEYASDIDLCDFDVENVDDLFDMAESPKKEKRKRGSTAPKADSKPATNGKAVKPAQEKSKAKPRYDSTSSQQSDRIWEEKFLQDSQVSLFQIDSLVVVNDTHLQPATPTGLAAPNTRSGAKQQGKLQAKPGEGAGSLNHSAAASVSTSSASTSSSRSRKKAATNKTANKAPPVSNSRPRMIHTEKAKMTRGASGESSGSATKKSRSKTYISRTETSNLGLDKTRSSASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQQRVQLMYDDNLLIDSALLREKTYDKFNPSMVNDLDDILRSPLKHERNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTAHGGSTPSSSSARTSRHLRQITANGTRAGSKRTAGGVASKSSPSPGVAAKKANTATKVSSSSSSYLGYGVDSYNVNVPASANNADVGSGFFSISEVVSAADAADAAAKAAAAGKTERKSRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605719;
90% Identity: -
80% Identity: -