Basic Information

Insect: Drosophila azteca
Gene Symbol: -
Assembly: GCA_005876895.1
Location: VCKU01000003.1:8637416-8639167[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.1e-06 8.7e-05 22.7 0.0 1 23 216 239 216 239 0.96

2 8 2.2e-05 0.0018 18.5 2.4 2 23 261 283 260 283 0.94

3 8 2e-05 0.0017 18.6 0.2 2 23 308 328 308 328 0.97

4 8 1.8e-06 0.00015 21.9 0.5 1 23 334 356 334 356 0.99

5 8 2.1e-06 0.00017 21.7 1.4 2 23 363 384 362 384 0.97

6 8 3.4e-08 2.8e-06 27.4 0.8 1 23 390 412 390 412 0.98

7 8 0.0011 0.094 13.1 0.2 1 22 418 439 418 442 0.91

8 8 0.00042 0.035 14.5 1.0 1 22 520 541 520 544 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.1e-06	8.7e-05	22.7	0.0	1	23	216	239	216	239	0.96
2	8	2.2e-05	0.0018	18.5	2.4	2	23	261	283	260	283	0.94
3	8	2e-05	0.0017	18.6	0.2	2	23	308	328	308	328	0.97
4	8	1.8e-06	0.00015	21.9	0.5	1	23	334	356	334	356	0.99
5	8	2.1e-06	0.00017	21.7	1.4	2	23	363	384	362	384	0.97
6	8	3.4e-08	2.8e-06	27.4	0.8	1	23	390	412	390	412	0.98
7	8	0.0011	0.094	13.1	0.2	1	22	418	439	418	442	0.91
8	8	0.00042	0.035	14.5	1.0	1	22	520	541	520	544	0.91

Sequence Information

Coding Sequence: ATGCCGCCGAACCAAGTTATTAATATTACCGATCTGAGCTGCCGCGTTTGCCTACAGACAAACGAAGGTGCATTGCGGTTGCATGACGAAATCCAGTACAATGAGCTGAACTTTGAGTTGTGGCAATTGCTGGAAACAGTCTCCAAAGTGAAGTGCACCTGGAACGAAGCAGATATGCCGACCCGCTTGTGTCAGAATTGCACACGCCGCTTGATAGCCGCCTATGAGTTTATCGTCGATGTGGAGAATGCACAGCACACGCTGCAGCAAGTGGCTGTGATGAAGGAGCCGGAGATTACCCATGTGGAGGTTCTGGAATTGGGTAGCCAGGACGATTTTTTGCCCATTATCTGTGACAGTGAGGAGGAGGTGGCTGTCGCGGTGGATGCAGAGCATCCTGCTGAAGCTGTGAGGGATGTGCCCTTCTCACAAGCAGAAGCGATAATCGAGCCAGTTTATGAAGCAGACCACCTGGAAGAATTTGAGACTAAAATACCATTTGTGGCTGAAGACTTGGATGTTACACCAAATGTGGATGAAGAATACATCGATGTGAAAGAGGATAAGgaggaacaggagcaggaaCTGGCAAAGTTGCGCCCATCGCTACTGGGCAGTCGTCTAACCCGTTCGCAGAATTTCATCTTTAAGTGTGAAATTTGTCCGCGTGTGTTTGCCAAAAATGATTCTCTCGCCCGGCACATCGCCGTTGCTCACAGTCAAACCGCGGACGTGGCCGCCCAGGAGCTGGCAAACGAGAGCATTGGAAGCGGCGTGCTGACTTGCAAGCACTGTCCACGCATATTGAAGCGCCAGGACACACTGCGTCGTCACATGCAGGCATTCCATCCAGAGGAAGCGGCCAAAGTTACTTTTGAGCCAACTGCCAGCTCACCGCGAAAACGCACCGCCAAGCGTCGTGAGTGTCCGCACTGTGGCATTAGTTTTCCCGCCTCCAGCCTGACCATCCACATTCGCCGGCACACTGGCGAGAATCCGTACAAATGCGACCAGTGCGAGAAGGCCTTTCCACGCAGCCAGGACCTCAGCTTGCATATTCGCCAGCACACGGGCGAAAAGCCCAGCGAATGTAAAATCTGCTCAAAGAAGTTCATATCCCAAAACAAGCTGGCTAGACACATGCGATTGCACACGGGCCAGCGTCCGTATGCCTGCGATAAGTGCGACAAGAGTTTCGTGCAATCCAACGACCTCAAGATTCACATGCGCAGACACACGGGCGAGCGTCCGTACAAGTGTGATGTATGCGGGGATAGCTTTGTCTCTGGCTCCCTATTGAATGTCCATCGGAATCAGAAAGGTCACCACATGACAGCATGTGGAAACCTGAGCCCTGGTGATACCACCACTGATGATCCTTATATAAATGCTCGTGTTAGCAATCGTCGAGCGGAGGACATTGAACGTATGCGGCGGAAACGGGATTCAGACGATCGACTTAACCAGCCACAAGCTGCGCCCGCACCAGCACCCGCTCCCTCGCAGCCCCAGACACCGGGGCCACAACAGTATTCACATCCGGTGAAGCCGCTGATCTACAAGTGTGGCGTCTGTGACTGGACCTTCAAGAGCGGTGCCTGTCTAACGATTCATCGCAACAACATGTCCCACTATGAGATCGGCAAAGTGGACTACGGTGATCCCTTTTCAAAGATGGTCAAAAGGCATAATTAA
Protein Sequence: MPPNQVINITDLSCRVCLQTNEGALRLHDEIQYNELNFELWQLLETVSKVKCTWNEADMPTRLCQNCTRRLIAAYEFIVDVENAQHTLQQVAVMKEPEITHVEVLELGSQDDFLPIICDSEEEVAVAVDAEHPAEAVRDVPFSQAEAIIEPVYEADHLEEFETKIPFVAEDLDVTPNVDEEYIDVKEDKEEQEQELAKLRPSLLGSRLTRSQNFIFKCEICPRVFAKNDSLARHIAVAHSQTADVAAQELANESIGSGVLTCKHCPRILKRQDTLRRHMQAFHPEEAAKVTFEPTASSPRKRTAKRRECPHCGISFPASSLTIHIRRHTGENPYKCDQCEKAFPRSQDLSLHIRQHTGEKPSECKICSKKFISQNKLARHMRLHTGQRPYACDKCDKSFVQSNDLKIHMRRHTGERPYKCDVCGDSFVSGSLLNVHRNQKGHHMTACGNLSPGDTTTDDPYINARVSNRRAEDIERMRRKRDSDDRLNQPQAAPAPAPAPSQPQTPGPQQYSHPVKPLIYKCGVCDWTFKSGACLTIHRNNMSHYEIGKVDYGDPFSKMVKRHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517881;
90% Identity: iTF_00471792;
80% Identity: -