Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:6265428-6267175[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 4.3e-06 0.00036 21.1 0.0 1 23 212 235 212 235 0.96

2 8 2.9e-05 0.0024 18.5 2.4 2 23 257 279 256 279 0.94

3 8 2.7e-05 0.0022 18.6 0.2 2 23 304 324 304 324 0.97

4 8 2.5e-06 0.00021 21.9 0.8 1 23 330 352 330 352 0.99

5 8 2.8e-06 0.00023 21.7 1.4 2 23 359 380 358 380 0.97

6 8 4.5e-08 3.8e-06 27.4 0.8 1 23 386 408 386 408 0.98

7 8 0.018 1.5 9.8 0.1 1 22 414 435 414 438 0.91

8 8 0.00056 0.046 14.5 1.0 1 22 516 537 516 540 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	4.3e-06	0.00036	21.1	0.0	1	23	212	235	212	235	0.96
2	8	2.9e-05	0.0024	18.5	2.4	2	23	257	279	256	279	0.94
3	8	2.7e-05	0.0022	18.6	0.2	2	23	304	324	304	324	0.97
4	8	2.5e-06	0.00021	21.9	0.8	1	23	330	352	330	352	0.99
5	8	2.8e-06	0.00023	21.7	1.4	2	23	359	380	358	380	0.97
6	8	4.5e-08	3.8e-06	27.4	0.8	1	23	386	408	386	408	0.98
7	8	0.018	1.5	9.8	0.1	1	22	414	435	414	438	0.91
8	8	0.00056	0.046	14.5	1.0	1	22	516	537	516	540	0.91

Sequence Information

Coding Sequence: ATGCCGCCGAATCAAGTTATTAATATCACCGATCTTAGCTGCCGAGTTTGTCTACAGACAAACGAAGGTGCCTTGCGGCTGCACGACGAGATCCAGTACAACGAGCTGAACTTTGAGTTGTGGCAGTTGCTGGAGACAGTCTCCAAAGTGAAGTGCACCTGGAACGAAGCAGATATGCCAAGCCGCTTGTGTCAGAATTGCACACGCCGCTTGATAGCCGCCTATGAGTTTATACTCGATGTGGAGAATGCACAGCACACGCTGCAGCAAGTGGCTGGGATGAAGGAGCCGGAGGTCACCCATGTGGAGGTTTTGGAATTGGGTAGCCAGGACGATTTTTTGCCCATCATCTGTGACAATGAGGAGGTGGCTGTGTCGGTGGATGTAGAGCATCCTGCTGAAGCTGTGAGGGATGCGATAATCGAGCCAGTTTATGAAGCAGACCACCTGGAGGAACTGGAGACTGAAATACCATTCGTGGCTGAAGACTTGGATGTTACACCAAATGTGGACGAAGAAAACATCGATGTAAAGGAGGGTGaagagcaggaacaggaagaGGAAGCTCCCTCCTTGGCTAAGGCGCGCCCATCGCTACTGGGCAGTCGGCTAGCCCACTCGCAGAATTTCATCTTTAAGTGTGCAATTTGTCCGCGTGTATTTGCCAAAAATGATTCGCTCGCCCGGCACATCGCCGTGGCTCACAGTCAGACCGCGGACGTCGCCGCCCAGGAGCTGGCCAACGAGAGCAATGGCAGCGGCGTACTGACTTGCAAGCACTGTCCGCGCATATTGAAGCGCCAGGACACACTACGTCGTCACATGCAGGCATTCCATCCAGAGGAAGCGGCCAAAGATACTTTTGAGCCGAGTGCCAGCTCGCCGCGAAAGCGCACCGCCAAGCGTCGCGAGTGCCCCCACTGTGGCATTAGTTTTCCCGCCTCCAGTCTGACCATCCACATTCGCCGGCACACTGGCGAGAATCCGTACAAATGCGACCGGTGCGAGAAGGCCTTTCCGCGCAGCCAGGACCTCAGCCTGCACATGCGCCAGCACACGGGCGAAAGACCCAGCGAATGCAAGATCTGCTCGAAGAAGTTCATATCCCAGAACAAGCTGGCCAGACACATGCGACTGCACACGGGCCAGCGTCCGTATGCCTGCGACAAGTGCGACAAGAGCTTCGTGCAATCCAACGACCTCAAGATTCACATGCGCAGACACACGGGCGAGCGTCCGTACAAGTGTGATGCATGCGGGGATAGCTTTGTCTCTGGCTCCTTATTGAACGTCCATCGGAATCAGAAAGGTCACCACGCGACAGCCTGTGGAAACCTGAGCCCTGGTGATACCACCACTGAGGATCCCTATATAAATGCCCGTGTTAGCAGTCGTCGAGCGGAGGACATTGAACGTATGCGGCGAAAACGAGATTCAGACGATCGACTTAGCCAGCCACAAGCTGCGCCCGCATCCACGCCCGCGCCCTCGCAGCCCCAGACACCGGGGCTACAACAGTATTCCCAGCCAGTGAAGCCGCTGATCTACAAGTGTGGCGTCTGCGACTGGACCTTCAAGAGCGGTGCTTGTCTAACGATCCATCGCAACAACATGTCCCACTACGAGATCGGCAAAGTGGACTACGGCGATCCCTTTTCAAAGATGGTCAAAAGGCATAATTAA
Protein Sequence: MPPNQVINITDLSCRVCLQTNEGALRLHDEIQYNELNFELWQLLETVSKVKCTWNEADMPSRLCQNCTRRLIAAYEFILDVENAQHTLQQVAGMKEPEVTHVEVLELGSQDDFLPIICDNEEVAVSVDVEHPAEAVRDAIIEPVYEADHLEELETEIPFVAEDLDVTPNVDEENIDVKEGEEQEQEEEAPSLAKARPSLLGSRLAHSQNFIFKCAICPRVFAKNDSLARHIAVAHSQTADVAAQELANESNGSGVLTCKHCPRILKRQDTLRRHMQAFHPEEAAKDTFEPSASSPRKRTAKRRECPHCGISFPASSLTIHIRRHTGENPYKCDRCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYACDKCDKSFVQSNDLKIHMRRHTGERPYKCDACGDSFVSGSLLNVHRNQKGHHATACGNLSPGDTTTEDPYINARVSSRRAEDIERMRRKRDSDDRLSQPQAAPASTPAPSQPQTPGLQQYSQPVKPLIYKCGVCDWTFKSGACLTIHRNNMSHYEIGKVDYGDPFSKMVKRHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517881;
90% Identity: iTF_00484573; iTF_00473950; iTF_00480999; iTF_00517881;
80% Identity: -