Basic Information

Insect: Drosophila auraria
Gene Symbol: ZNF526
Assembly: GCA_008042615.1
Location: VNJW01012075.1:23356-25410[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.14 14 6.6 0.2 1 21 331 351 331 352 0.95

2 10 4.2e-06 0.00042 20.9 0.3 1 23 360 382 360 382 0.98

3 10 0.00058 0.058 14.1 1.4 1 23 385 408 385 408 0.92

4 10 1.1e-06 0.00011 22.7 0.8 2 23 415 436 414 436 0.98

5 10 2.8e-08 2.8e-06 27.7 1.0 1 23 442 464 442 464 0.98

6 10 3.5e-06 0.00035 21.1 0.6 1 23 470 492 470 492 0.99

7 10 0.00029 0.029 15.0 2.3 1 23 498 520 498 520 0.98

8 10 0.00085 0.085 13.6 0.3 1 23 526 548 526 548 0.98

9 10 7.9e-05 0.0079 16.8 3.7 1 23 554 576 554 576 0.99

10 10 0.00069 0.068 13.9 0.1 1 23 582 604 582 604 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.14	14	6.6	0.2	1	21	331	351	331	352	0.95
2	10	4.2e-06	0.00042	20.9	0.3	1	23	360	382	360	382	0.98
3	10	0.00058	0.058	14.1	1.4	1	23	385	408	385	408	0.92
4	10	1.1e-06	0.00011	22.7	0.8	2	23	415	436	414	436	0.98
5	10	2.8e-08	2.8e-06	27.7	1.0	1	23	442	464	442	464	0.98
6	10	3.5e-06	0.00035	21.1	0.6	1	23	470	492	470	492	0.99
7	10	0.00029	0.029	15.0	2.3	1	23	498	520	498	520	0.98
8	10	0.00085	0.085	13.6	0.3	1	23	526	548	526	548	0.98
9	10	7.9e-05	0.0079	16.8	3.7	1	23	554	576	554	576	0.99
10	10	0.00069	0.068	13.9	0.1	1	23	582	604	582	604	0.96

Sequence Information

Coding Sequence: ATGGACATCGATAAGATTTGCCTGACCTGCCTGAGCTCGACAGGTCCCTTTCTGTCCATCTATGACAACGGATCGGGTAGCTGCTTGGCCGATATGCTCAGGGAATTTACAAAAACCAAGCCGCGTCGCCACGATAATCTGCCGGAGAAGGTGTGTCTGGGCTGCTTGAGTGAAATAAACCACTGTTACACGTTCAAGATCATGTGTGAGAACTCCAGTCGAACCCTGCGCCAATTGCTGCCAAATGCCCTTCCCGAGGAAGAGGACCTGGAGAAGGCGTCCATCAAGCAGTCGGTGCCCACCAACGATCAGGCTATGCAAACTCCCAACTGGGAGTCCAGCCGGTCCACGGTGTCCACACAAACGGATTCAGTGGTCATAGATAACGGCAGTCTGGTTAAGCGCAGGATTTCATTGCACTTGGACGACGACGAAGATGACGGAGACGGTGATGGTGAGGGAGAAGTATTCGATTACGAGCTGACCGACGAGCCCGTGGAGAAGACAACCAGCATAATCCTGCAAGTACAGGAAAGCTTGAAAGTTGAAAAGGAGGTCGTCTACACTCATGCAAATGTCATTTATGAGGGCGATGACAACGAGCTGGAACAGCAGATCCGGGAGTGCAATCTGGCCATATTTGACAGTGTCGAGAATGAGGTTCCAGGTGTCTCAATGCAAGCCACAAGGAAAAGCGCAGCTAAACTtctgatgcagcagcagcaggaggctGTTGCTAAGCAAGAAGAGGAGGCTGCTCCTAAGCAGGAAGCTGAGCCGGCGAAGAGATCCTCTCGCCGAAGGGCAGCTGAAAAGCAGGAGGTGCATACCACGTCAGAGGCCTCCACATCCTCTCCCTCGAAGCAGCTGCGGATGGGAACCAGCCGCAGATCACTCAACTCAGTGGTAGTAGCTGGAGCCACCTCGTCCTCCGCGGCTGGAGAAACTAGCACAGGAGAAGCAGGTGCTTTTTTAGTAACTGAGCTAAAATACCATTGCGATCGCTGCAATGCTGGTTTTGCTCTGGAAAAATCCCTAATTATCCACAAAAGACAGAACAGTTGCACGAACCGGAATTTCAAATGCGATGAGTGCGAAAGGGTCTTTGTTTCGCCGGATCATCTTGCCGAGCACCGCGCCAGTCATGGCTCTCACAATTGTCCGGAGTGTGGAATGAAGTGCGAGTCCAAAGAGCAGCTGGGTAAGCACATGGTCCAGGGCCACAAGCGGAATCTGCGAAACCAGTGCAACGTTTGCCAAAAGGTTTTTACCATGCTGTCAACGCTGCGTGACCACATGCGCATCCACACAGGCGAGAAGCCATTTGTCTGCAATATCTGTGGCAAGAGCTTCACGCAGAACGCCAATCTGCGCCAGCACAAGTTACGCCACTCGGAGACGAAGAGCTTCAAGTGCGAGCTGTGCCCGCACTCGTTCGTAACCAAGGCGGAGTTGGCCTCGCACGCCCGCACCCACACGGGCGACAAGCCCTTCGAGTGCGAGGTGTGCGCGGCAAGGTTTACCACCAGCTGCTCGCTGGCCAAACACAAACGTAAGCACACCGGCGAGAGGCCTTACGCCTGCGATCTGTGTCCCATGAGGTTCACCGCCCTTAATGTGCTTAAGAACCACCGGCGGACGCACACAGGCGAGCGTCCATACGTGTGCCCATTCTGCTCAAAAACCTTCACGCAGCGTGGCGACTGTCAGATGCATCAGAGGACACATCAGGGCGATCGCATCTACATTTGTCCAGTGTGCAACGAGGAGTTCACGACAATGCCAGAGATGCGAACGCATTTGTCCGGACACGAGCAGCATGACAAGCGGCTGGTGCACTTTACCCTTATTAGCAACAAGGAGAACGGAAGCGGTCCACTCGAGGATGATATTAACGAGATGGCAGAGTCGGCGCTGATGATATAA
Protein Sequence: MDIDKICLTCLSSTGPFLSIYDNGSGSCLADMLREFTKTKPRRHDNLPEKVCLGCLSEINHCYTFKIMCENSSRTLRQLLPNALPEEEDLEKASIKQSVPTNDQAMQTPNWESSRSTVSTQTDSVVIDNGSLVKRRISLHLDDDEDDGDGDGEGEVFDYELTDEPVEKTTSIILQVQESLKVEKEVVYTHANVIYEGDDNELEQQIRECNLAIFDSVENEVPGVSMQATRKSAAKLLMQQQQEAVAKQEEEAAPKQEAEPAKRSSRRRAAEKQEVHTTSEASTSSPSKQLRMGTSRRSLNSVVVAGATSSSAAGETSTGEAGAFLVTELKYHCDRCNAGFALEKSLIIHKRQNSCTNRNFKCDECERVFVSPDHLAEHRASHGSHNCPECGMKCESKEQLGKHMVQGHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELASHARTHTGDKPFECEVCAARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGDRIYICPVCNEEFTTMPEMRTHLSGHEQHDKRLVHFTLISNKENGSGPLEDDINEMAESALMI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491650;
90% Identity: iTF_00609303;
80% Identity: -