Basic Information

Insect: Drosophila atroscutellata
Gene Symbol: prg
Assembly: GCA_035041605.1
Location: JAWNLA010000092.1:7409090-7410955[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.24 15 6.2 1.1 1 19 226 244 226 249 0.85

2 9 0.0011 0.073 13.5 0.2 1 23 255 278 255 278 0.97

3 9 5.3e-06 0.00034 20.8 0.3 1 23 284 306 284 306 0.97

4 9 1.1e-07 7.1e-06 26.1 4.3 1 23 312 334 312 334 0.98

5 9 2.9e-05 0.0018 18.5 0.6 1 23 340 362 340 362 0.98

6 9 5.9e-05 0.0037 17.5 0.3 1 23 368 390 368 390 0.98

7 9 3.3e-05 0.0021 18.3 0.5 1 23 464 486 464 486 0.96

8 9 2e-05 0.0013 19.0 0.2 1 23 491 514 491 514 0.91

9 9 0.043 2.8 8.5 0.6 1 23 518 540 518 540 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.24	15	6.2	1.1	1	19	226	244	226	249	0.85
2	9	0.0011	0.073	13.5	0.2	1	23	255	278	255	278	0.97
3	9	5.3e-06	0.00034	20.8	0.3	1	23	284	306	284	306	0.97
4	9	1.1e-07	7.1e-06	26.1	4.3	1	23	312	334	312	334	0.98
5	9	2.9e-05	0.0018	18.5	0.6	1	23	340	362	340	362	0.98
6	9	5.9e-05	0.0037	17.5	0.3	1	23	368	390	368	390	0.98
7	9	3.3e-05	0.0021	18.3	0.5	1	23	464	486	464	486	0.96
8	9	2e-05	0.0013	19.0	0.2	1	23	491	514	491	514	0.91
9	9	0.043	2.8	8.5	0.6	1	23	518	540	518	540	0.98

Sequence Information

Coding Sequence: ATGCTCGATTTAACGACGATCGACGTAGGAACACTTAATTGGGACCAGAAAAATGATCAAAAATTAACATCGGAGTCAATGCGATGTCGCTTGTGTCACTCACGGATAAAATTGAACACAGATTCGCCGAATATTTACGAGGCGTCTGTTTACTTTGGCCAGGAAGAAGAAGATTTAagaacagaagaaaaaatcataattgcCGATGTTTGCCAGAGTGTTTATGGTGTGAAATATGAGCGCCATGAGTTACTGTCGGAGCACATCTGTATGCGCTGCCTGGAGATATTGAGGGATTTCTACGAGCAACGTCAGTACATGCAGCAGCATGAAttggagctgcagcagaacctaaagaaaataattgctGTGGATGCCAAGTATCGACCTGGCCTCAACGGCAATCCAGGCGAGTTTGAATTTGGGGAAGGTGAAGAAATTGTCGATGTGGATCCCGACCAACTGTGCGAGACGAGTGATGACGAATTCCCCGGCTCCGAAGGTGAAGCTGAACTCGATGATGAGGAATGggacgacgaggatgaggagggAGGACCTGCACAAAATGAAGAAACCGAGATACCCCTCGGCATGGATGCCGCCCAAATGGCGATGATGCGAGTGCATCAAACGGTCGACACCAGTGTCCAATTCAATGCGCATCCAAAGAGCGCCTTCCTCTGTCAGTACTGCGATCTGGCCTTCACCCTACAGTCGGACTGCCAGCAACATGAGGTGGGCTCCCACGACTCCTCGGCGCCGTACACTTGCAACTACTGTCAGATGAGATTGATGACGCGTCCGGCTTTAATTGCGCACATCAGGGAGCAGCATGACGCCGAGCGTCCCTATGTGTGCGCACTGTGCAGCAAGGGATTCGTGAGACGTTCGGACTTGAAGAAACACACAATTGTGCATACGGGCGTGCGTCCGTTCTCGTGCCACGTTTGCTCCAAGAGCTTCTCGCGCAACACCAATCTGACCAAGCATCTACGCATCCACAGCAGCGTGAAGCCGTTCGTCTGCCAGCAGTGTCCGCGCTCTTTCCAGACACCGCTGGAGCTGCTGAAGCACACGCGCTCCCATGCCGAAGTAAAACCGTTCCGGTGCGGACGCTGCCCCGCCTCGTTCGCCCGCAAGGATAAGCTATTGATGCATCAGCAGGTTCATCTCAAGCGCGACATcgagcaaaagcaaagtcaaAATCTGCGCATCAATATGATGATGCCGGTAGAGCAGATGCAAgtgcagctgccactgcaTCCGTACGTGGAGGCAGATGCATCGGCCCAACAGGCTTTACCAGCTATAACACAATATTCATATCAGCAGCAAACGCCTCCCGCGATGCAGCCAAAGGTGAAAGCATCGCCGAAGGTAACGCGCAATTTCCGCTGCGATGTATGTGATCGGGGCTTCCAACGAGAGCGGGATTTGCAGCGCCATCGGGCGCTGCACATGGACTCACTATTCGCCTGCAAACTGTGCGGCCAGGGCTTTAATCGGCGCGAGCAACTCCAGCGTCACGAGCTGGAGGCTCATGGACCCAGCTATACATGTGCTATTTGTTGCATCACTTTCCTACAGCAGGCGGAGCTGGAGACGCATCTTAAAGTGCACGAGCTGCAGCACAGTGTAGCCAAAAGCAACCAGGAGGCGTTAATAGCTGCCGCCGCTGTAGTACCGCTAGCTCATTCCATGGGCGAGCACACGGGTGTCCCAGTGCCAGCCATCGTTCCGGAGCCCGCCCAACTACCCAATGTTAGGCCTTCTGCAGCTGAAATGTCCTTCTATAGCAACATGATACCTACCATGAATCTAGGCTTCTACAGCGAGACGCGTCCCGAAGAGAGCAACGGAGTTTAA
Protein Sequence: MLDLTTIDVGTLNWDQKNDQKLTSESMRCRLCHSRIKLNTDSPNIYEASVYFGQEEEDLRTEEKIIIADVCQSVYGVKYERHELLSEHICMRCLEILRDFYEQRQYMQQHELELQQNLKKIIAVDAKYRPGLNGNPGEFEFGEGEEIVDVDPDQLCETSDDEFPGSEGEAELDDEEWDDEDEEGGPAQNEETEIPLGMDAAQMAMMRVHQTVDTSVQFNAHPKSAFLCQYCDLAFTLQSDCQQHEVGSHDSSAPYTCNYCQMRLMTRPALIAHIREQHDAERPYVCALCSKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSVKPFVCQQCPRSFQTPLELLKHTRSHAEVKPFRCGRCPASFARKDKLLMHQQVHLKRDIEQKQSQNLRINMMMPVEQMQVQLPLHPYVEADASAQQALPAITQYSYQQQTPPAMQPKVKASPKVTRNFRCDVCDRGFQRERDLQRHRALHMDSLFACKLCGQGFNRREQLQRHELEAHGPSYTCAICCITFLQQAELETHLKVHELQHSVAKSNQEALIAAAAVVPLAHSMGEHTGVPVPAIVPEPAQLPNVRPSAAEMSFYSNMIPTMNLGFYSETRPEESNGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00511438;
90% Identity: iTF_00610063;
80% Identity: -