Basic Information

Insect: Drosophila atripex
Gene Symbol: zfh1
Assembly: GCA_035045925.1
Location: JAWNOP010000069.1:9837689-9857669[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.00041 0.032 14.7 1.9 2 23 73 95 72 95 0.95

2 9 0.0049 0.38 11.3 0.1 1 23 302 324 302 324 0.96

3 9 9.7e-05 0.0075 16.7 1.7 2 23 338 359 337 359 0.97

4 9 4.7e-06 0.00036 20.8 6.3 1 23 368 390 368 390 0.99

5 9 0.00028 0.022 15.2 1.2 3 21 398 416 396 417 0.94

6 9 0.0065 0.5 11.0 0.7 2 21 639 658 638 659 0.92

7 9 3.2e-05 0.0025 18.2 0.5 1 23 981 1003 981 1003 0.95

8 9 4.7e-05 0.0036 17.7 7.4 1 23 1009 1031 1009 1031 0.98

9 9 0.0023 0.18 12.3 4.3 1 21 1037 1057 1037 1058 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.00041	0.032	14.7	1.9	2	23	73	95	72	95	0.95
2	9	0.0049	0.38	11.3	0.1	1	23	302	324	302	324	0.96
3	9	9.7e-05	0.0075	16.7	1.7	2	23	338	359	337	359	0.97
4	9	4.7e-06	0.00036	20.8	6.3	1	23	368	390	368	390	0.99
5	9	0.00028	0.022	15.2	1.2	3	21	398	416	396	417	0.94
6	9	0.0065	0.5	11.0	0.7	2	21	639	658	638	659	0.92
7	9	3.2e-05	0.0025	18.2	0.5	1	23	981	1003	981	1003	0.95
8	9	4.7e-05	0.0036	17.7	7.4	1	23	1009	1031	1009	1031	0.98
9	9	0.0023	0.18	12.3	4.3	1	21	1037	1057	1037	1058	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCGTCGTCTTCACGTTTCGGCCAAGAGGATACCATCATTCAGCAGAGCATGCCATCCACAGCCTTCACCATGCAGTTTCCCTCGCTGGCCCCCAGTCTGCACCACCACAGCCACAACCAGTCGCCGCACCACAGCAAGCCCGGACCCCAGGATGGCCAGCACGTGCAACCAGGTGCCGCAGCCGATGATTTTCTGGTCAAGTGCACCCAGTGCCACAAGCGATTCACAGACTTTCAGtcTCTGAGCGAACATATTGCCAGCGAGCATCCCCACGACAAGTTGAATTTGGGAGCTGCGCAACCGGAAAGCGAACCGGAAGATGAGCAGAGCAACTTAAGCAGCGGAAGTCGGCGATACTTGAAGTCGCCAACCACCAGTATTGGCAATACAAATGCCAACGGCAACACCAGTATTGCCAACtccagcaataacaacaacaacaacaacaacagtgatCTGGCCAAGAACCACAACAACACGAACAAACTGTCGCCAATGTGCTCCCCCATTTCCAGTGTAAGAATGGGCGGTGTGGGAGCAGGTCCACCCAGCGATCTCTTCGCCCACCTCTCCCATGCCACGCCCGCCCACCTGCAAGCCCAGTTAATGGCTGCCGCCGCCCTGGCAATGCAATCCGCCCGCTCCGCCAGCTCCAGTTCGCCGAGCCACCAGCAACAgtcccagcagcaacagcaatcggcgcaactgcaactgcaataccaccaacagcaacagcagcaacagcaacaccagccgCCCCTCTTGCCGCCTCAGCTTCCAGGTAGCAACAGCAGCGTTGGCAGCAACTCCGCCTACGATCTGGATCTGAGTGCACCACGATCCACCTCCAGTCCCGGCTCCACCACCGGGGACCTCAGCGGGGCATATCCCTGTATGCAGTGCACCGCCGCCTTTGCCTCCAGggagcagctggagcagcaCGAACTCCTGCACTCGCCGTGCGGACAGCCATCCACCCAGAACGTCTCACAGACCTGCCGCATCTGCCACAAGGCCTTCGCCAATGTCTACCGACTCCAGAGGCACATGATCAGCCACGATGAGAGTGCCCTGCTGCGGAAGTTCAAGTGCAAGGAGTGCGACAAGGCCTTCAAGTTCAAACACCACCTCAAGGAGCACGTGAGGATCCATTCCGGCGAGAAGCCATTTGGGTGCGACAACTGCGGCAAGCGGTTCTCGCACTCCGGAAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGACTCAAGCTGAACAACAACCGGGCTCTGCTGAAGCGACTGGAAAAGGGTCCAGGCGCTGGCTCGTCGGCACGCCTCTCGCCGTCGGACCAGGCCAAAGCCAAGctccaggagcagcagcccCTGCCGGGCCTGCCGAACCCAATGATTTACTTCGCCAGCGATGCCCAGAACCAGGCGGGCAACAGTGGACCCGCTTCCTTCCCGAACTTCCATCCCACAAACTACATGAACGCTGCCCTTCTGGCCTTTCCTAATCCCTTCATGGCAGCTGCCCTGGATCCTCGTATGCATCCCTATAGCATCCAGCGATTGCTACAATTGACGGCTGCCGGTCAGCAACAACGGGAAGAGGAACAGCATGACCAGGAGCAGGAGATCCACGAGGAGGAGACACCGGATGAACCCAAGCTGGTGATGGATATCGATGAGCCGGAGATTAAGGAGCGGCCGGCCACCCCCCAAGTACGTGAGGAAGTCGCTCCCATCAAGCAGGAAGCCAGTCGCGAGGACTCTCCGGCTCCGGAGAGTAATCCTCCATCGCCGCAGGTCATCAAGCAAGAACCGGAGGCACAAACGGTAGAGCCAGAGCCCCATGTTATGGAGGAAGAGCCCATTCCAGCTCCAGAACAACCTGCCGACCTGCGCTGCAGTCGCTGCTCGAAGCAGTTCAACCATCCCACGGAACTGGTGCAGCACGAGAAGGTTCTCTGTGGCCTCATCAAGGAAGAGATGGAGCAACActtccagcaacaacaacagcagcagcagcagagcctACAGCCGCCACCCTTCGTTTTGCCGTCCGCCAGTGAGGAAgatgatgaggaggaggaggaggagcccaGAAACCAGGAGACTGGCGAACGGAAAGTCCGCGTGCGCACGGCCATAAacgaggagcagcagcagcagctgaagcAGCACTACTCCCTGAACTCCCGACCCAGCAGGGACGAATTTCGCCTCATAGCCGCCAGATTGCAGCTGGATCCCCGAGTGGTGCAGGTGTGGTTCCAAAACAATCGCTCCCGAGAGCGCAAAATGCAGAGTTTCCAAAGCAACCAGGGCGCCACTGTCCCTCCCACAACCGAATCCCAATCCGGTGCATCCCGTGAAGATCAGCCGCTGGACCTGTCCGTTAAGCGGGATCCTCTGACCCCAAAGAGTGAGAGCTCGCCGTCGTATATGCCTCCACAGACGGCTGAAGCTCTCAATCCGGAAGCCATCAACTTGAGCCGGAAGTTCTCCAGCTCCGCCTCGATGTCCCCGGCTTCGATTTCACCCTCGTCCGCGGCAGCCTTGTATTTCGGAGCCGCACCGCCGCCGTCGCCGCCAAACAGCCAACTGGAGACCAACACTCCACGCAACAATCAAGCCTTCCCGGGATTACCTGCCTACATGCTCCCCATGCAGCGACTGCCCATGGAGGCCCTTTTTCAGATGCGACCCGGTGGAGAGTATGGACCAAACCATCCCCTGATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTGAGCCCGGGAGGATCGGAGAAGCGCTCGTGGCGGGACGATGACTCGCGCATCTCACACGAGGACGACTTCTCCGGCGGACTGCTGCCCCCGAAGCAGAGGAGAGGCAAGGCGGAGACCCATGGACACGCCGGCGACCCGGACTTGCCGTATGTCTGCGACCAGTGCGAAAAGGCGTTTGCCAAGCAGAGTTCCCTAGCGCGTCACAAATACGAGCATTCCGGTCAACGACCCTACCAGTGCATGGACTGCCCGAAGGCCTTCAAGCACAAGCACCACCTGACGGAACACAAGCGCCTCCACAGCGGAGAGAAACCCTTCCAGTGCTCCAAGTGTCTGAAACGATTCTCGCACTCCGGCAGCTACAGCCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSSRFGQEDTIIQQSMPSTAFTMQFPSLAPSLHHHSHNQSPHHSKPGPQDGQHVQPGAAADDFLVKCTQCHKRFTDFQSLSEHIASEHPHDKLNLGAAQPESEPEDEQSNLSSGSRRYLKSPTTSIGNTNANGNTSIANSSNNNNNNNNSDLAKNHNNTNKLSPMCSPISSVRMGGVGAGPPSDLFAHLSHATPAHLQAQLMAAAALAMQSARSASSSSPSHQQQSQQQQQSAQLQLQYHQQQQQQQQHQPPLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTAAFASREQLEQHELLHSPCGQPSTQNVSQTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKGPGAGSSARLSPSDQAKAKLQEQQPLPGLPNPMIYFASDAQNQAGNSGPASFPNFHPTNYMNAALLAFPNPFMAAALDPRMHPYSIQRLLQLTAAGQQQREEEQHDQEQEIHEEETPDEPKLVMDIDEPEIKERPATPQVREEVAPIKQEASREDSPAPESNPPSPQVIKQEPEAQTVEPEPHVMEEEPIPAPEQPADLRCSRCSKQFNHPTELVQHEKVLCGLIKEEMEQHFQQQQQQQQQSLQPPPFVLPSASEEDDEEEEEEPRNQETGERKVRVRTAINEEQQQQLKQHYSLNSRPSRDEFRLIAARLQLDPRVVQVWFQNNRSRERKMQSFQSNQGATVPPTTESQSGASREDQPLDLSVKRDPLTPKSESSPSYMPPQTAEALNPEAINLSRKFSSSASMSPASISPSSAAALYFGAAPPPSPPNSQLETNTPRNNQAFPGLPAYMLPMQRLPMEALFQMRPGGEYGPNHPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDFSGGLLPPKQRRGKAETHGHAGDPDLPYVCDQCEKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615732;
90% Identity: iTF_00550414;
80% Identity: iTF_00481450;