Basic Information

Insect: Drosophila asahinai
Gene Symbol: Trerf1
Assembly: GCA_008042795.1
Location: VNJZ01009084.1:507158-517373[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.037 3.4 8.5 1.7 2 23 162 183 161 183 0.97

2 6 3.5e-06 0.00031 21.2 1.3 1 23 189 211 189 211 0.98

3 6 0.00034 0.031 14.9 2.5 1 23 217 241 217 242 0.94

4 6 0.00057 0.052 14.2 0.8 2 23 519 540 518 540 0.97

5 6 0.0016 0.14 12.8 0.1 1 23 1689 1713 1689 1713 0.98

6 6 7.7e-05 0.007 17.0 0.8 1 23 1846 1868 1846 1868 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.037	3.4	8.5	1.7	2	23	162	183	161	183	0.97
2	6	3.5e-06	0.00031	21.2	1.3	1	23	189	211	189	211	0.98
3	6	0.00034	0.031	14.9	2.5	1	23	217	241	217	242	0.94
4	6	0.00057	0.052	14.2	0.8	2	23	519	540	518	540	0.97
5	6	0.0016	0.14	12.8	0.1	1	23	1689	1713	1689	1713	0.98
6	6	7.7e-05	0.007	17.0	0.8	1	23	1846	1868	1846	1868	0.98

Sequence Information

Coding Sequence: ATGTGCAGCGCCTCCGTGGGCACCGAGGGATCCGTGACTCTGCAACTGAGGGATGCGAACGCCTTGGAGGCGACCACATCAAGCTCTTCGAAGACAGCAaccagcggaggaggagcagcggcggcggcggcaggagcaggagcatcgTCCACGAATGGCGCTGCAACTGCGTCAGCGGCGACGCTAGAGAATGCGCTGACCATCGGCTATCCGGATCCGGAAATGTTGGCAGATGTCTTGGGCACCATTCAGACAGCCTCTCTTAAAAACCACAACACCAACTCAATCACAGCAAGCAACGGACACGGGCACGGACACGGTCACGGCAGGCATGTGCCCAGCTCCGGAGGAGTAAGCACAGCGGCGGCCGCCACTAGCAACAGCTCGAACGGGATAGGGATAGGGATTGGCGGGATCATCAGCGTTGAAGCGCCGCGCAAGAATCGCCCCAAATTATCCTCACCGACGCGACACGGTCCGCAGCAGTGTCAGACTTGTTGCAAGATCTTTGGAAATGCCTCGGCGCTGGCCAAGCACAAACTGACGCACAGCGACGAGCGGAAATACATCTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACTCATCGGAACAAGAAGCCTTACGAGTGTAAGGCGGATGGCTGCGGCAAGTCCTACTGCGACGCCCGCTCCCTGCGGCGTCACTCGGAGAACCACCATGCCGGCGGCGCGACCacgcccaccaccaccagccagCAATCACTCTCGCCCACCGCCAGCTCGAGTGgggcgagcagcagcagcgtgggcgtggccaccaGCTCGCTAAGTCTCTCGCCGGCCACGGCCAGCGGGGATGCCAGCTCCCCGGACGGGGCCACCTGCATCCGCACCTACATCTCCACGGGCAGCTCGGTGGTGGACGCGGCCACCGGGATAGCACTGTCGGACGAGCAGATCAAGGCCATGAACTTGCCGATAAAGACGGGCGTGACCCTGCTGTCGCCCACCACCTCGACCTCGTCGAATGCCTCCTCCACGGCCTCGTCATCGTCCTCATCCGCCTCTGCCTCGGCCTCCATCTCGTCGCTCTCCTCGGCCTCATCTGGTATTGGCCTAACGGCGGTGTCTTCGCCCTCCAGCGTGGGCACCGTGATAGCCACCAGCTCGCCAGCGCCGACCATCACGCTCAGCGATGGGATGAGCCTCGAGGGCGAGGGCCTGACCCGGGAGCAGCTGGACCTCATCAGCAAGATCATGCAGCAGACGAAGCAGACGAGCGCCCAGGTCACGGTCTCCTCGCCCACCAGCGTCAGCTCCTACAAGATCAACACCAACCAGGCGCCGTCGCAGTCGAGGCCAAGAACCTGGAACATGCAATTGCTCAACAGTGCACAGAATGTGACGGTCACCGTCGAGGACAACACCGAACTGGTGGCTCCCTCTTCCAGCTCCCCCGTGGAggtcaaggaggaggagctgagTCCGCAGCTAGTGGCCGCCATCAATCCCCACCTGCTCAACATTGTGAAGCTCGACAAGCCCGTCGAGTGCAATCTGTGTCACCGCAAGTTCAAAAACATACCCGCCCTCAACGGGCATATGCGCCTCCATGGCGGCTACTACAAGAAGGATCCGGAGACCAAGCGCAGCGAGAAGAAGGACTCGAGTGGTCCGCCCCTGCAGACGGCCAGCATAGGAGTGCGTGCCCTCATCGAGGAGAAGATCATCAGCAAGCGCAAGGACATGACAAAGGGCTCCTTCGTGGTTCCCGCGCCCCCACACAGCagcggcaccaccaccaccctgCGGCGGTCCATCAGCGACCTGGAGAGCTTCCTCAATCCAAAGAGCAGCTCGAGTGGCCACACCCAGACCCTGAACACGGGAACAGGCACCACCACAGCGGTGCTGCCGGCGGCCACCACCATCAAGAGCAGCAACGGGCTGAGCATTCAGCAGATCGGCCTGCCGCAGAGCATCGAGATCTTCAGCGGCGGCCAGAAGCAGGCAAAGACCCTCAACCTGGGCAGTGGCACCAATACCATCACTATAACCACCAACAATGTGCCCACCACCACGACGATGAGTGCTCTGACCGCCCTGAAGGCCGGCGGCACCATTAGCGGCATTTCCACGGCCACCAACACGGATCCCAAGGACTCGACGCTGATAGAGCTCCTGAAGCGGGGCACACGCATCGCGGTCACCTCGAAGAAGGCGCAGGCCCAGTGCCAGACGACATCCGGTGTCCTGATGACCTCCAGTTCCACGGCCACGCAATCGATGGGCACCCTCACCGAGCTGACCACCATTGGCGGGAGCAGTGTGCAGGCGGTGGGCCGCCAGATCATCACGAATAACAATCGCACCGTGATCATACCCTCCGACGTCCAGGTGGTGTCCACCAAGAGCAAGCTGACCAGCCTGAGCACTCTGAGCAGTCTGGTGAAGAGCACTGTTGCCACAACCACCAGCAGTTCCACCAATACCAGCTGCTCCTCGGGAAATCTCTCGCTGGCAGACGGGACTCCCCTCTCGCTGACCATAGCGCCCAGCCAGGATGTATCCGGTGGAGGAGGTGTTCCGAGTGGGACTGGCAGCGTGATCAccagcggaggcggcggcgtcTACACGGTGACCTACACCAGCGACGGCACCGATCTCTTCGACGACGCCGAGGTGTACAACGTGTCCGACACGGAGATGCTGCTGCAGACGGTAGACTCGATGGAGCTGCTgcacgacgacgaggaggagccgcAGATCAAGAGCGAACATTCCGAGGACTTTGCCATGCTGAGCGAGGCCGGCGACAGTGCGCACACCCAGCTGGTGAAGCTGGAGCCGGAGAGTGGGCAGGCCAGCGGCAACTCCTCctcaggaggaggaggaactggAGCCAACACCACGCCGCTGCCCACCTTCCAGCAATTCCATTCCAAGGAGCTGATCATGCAGAACAGTTCGCAGATCCAGGCGATAGCCAGCATGCGGCCAAGTGGAGCTGGTtccggagcaggagctggcaATGGCAGTGGCGTCCTGGCCTCGCCGCTCCACTCGCCGCTGGCCTATCCCACGCCGCCGTCGAGCCACGAGAACATGGCCCAGAGCTCGCCGTTCATCGAGGATGCGGCCGCCCAGTTCGTGGACGCCAGCAACACCTTCTTCGGCGACAAGACGGACTTCTCGCACATCTACTTCAAGACGGACGAGGGCCAGGCCACCATCGAGCAGATGAACGAGCACGACAACGAGAAGATCCTCAAGCTCAAGTCGGTGCTGGAGGAGAGCAGCTTCGATCCCTCCATCAAGGTGGAGGACCTGCTCAACGGCACCGACGACGACACCGAGTGCGATCTGCGAGAGTTCGCCGAGACGAATCTCTCGTTCCTGGACGAGGATCAGGAGTTCCTCAACGATTCCCGCAATGCCACCTCCCCGCTCTCGGAGTCCTTCTTTACCAGCGGCATAGGCTCGGCGGAGGATGTGAAGCAGGTCCTGCGGGAGGTCCTCCCGGATGAGAACATGCAGCTCCAGCTGACCAGCGAGCAACAGGGCGAGAACATCATCGATCTGTACTACCTGCCCGGCCTGGGACTGCAGTCCCAGATGATGCCCAACTCGGAGGACCCCCTGCTGTCCTCGTCGCCCAGGGAGtttggccagcagcggcagcagatgAGCAGCATCCAGCCcttggagcagcagctccagcagaaTGGCAACCTctaccagcaacagcagcagcaggagcagcagcagcagacgcagcagctccaggagcagcaacagccccAGCAGGAGCcatcccagcagcagcagcagcagcagcaataccAGCAGATCCTGCTGCCCCAGCAGACGGCTAATCAAGGGGAATCCCTGCCAGCGGTGGTCCAGCAGCAGGCCGACTTCATGCTGCCCCTGGTGGGGGGACATGGCTTCGCCCAGGTCTCCTCCGGCCAGGCCCAGTACGTGGACAATGGCCAGGGCAACATGCAGGGAATGCAGCCCCTCAACAGCctgctgcagccgctgctCTACCAGGGAGGAGTCACCTCCAATGGcattgccgccgccgggcAAGAGGGCCTGTTGTCCACTGATTGCCAAATGAATGCCAATCAGAGCCAGACATCGACTCTGGATGCCGGACTGCTGTTCGCCTGCGgcaacaccaccaccacaaccAGCAATGCAGCCACGACGACAATGGGTGGTAATAAATCCCTGCTAGCCTCGGGGCCCCTTTCCGGCTCTGTGTCCAACCTGCAGCCGCTGTCGAACCAAACCAATTCCATTCTGAAGCGCCGCCTGCGCTCGAGTGCGCCCCAGGAGACGCACAAGTTCTCCAAGTTCCACACGCTCTCGCCGCACCGCTCCAAGCTGCGCAAGCCCTCCCGCACCCACTACACGCCCGCTCCGATCCTGAATCCGGATCGCAAGGGCACCGGCCTCTACTGCAGCGTCCGCAAGCAGCTGGGCCTGAGCCAGGGCCTCTTCGATGCCTTCGACGACGACTTTGGGGATCCGGTGGGTCTGGTCGACTTCTCGGACGAGTCCAAGGTGAATCTGGGTTCCACCTACCAGGCGCAGATACCCAGCTGCCGGTCGCCCGAGGAGGCTGTGCGAGACTCGCCCTGCGCCGAGCTGATGTGGAATCCGGAGGTGCAGGAGGACGAGAAGATCCTGATGCGGTACATTGATCTCAGCAAGTCGTCGGCCGTGCCCATGGGCAGTCATTCCGAGGAGGTGGCGCTCCACACGCTGCTCAAGGCCAGGGGCAACTCGGCGGCAGCGGTGCTCACCCTGCTCCAAACCCAGTCCGGCGCCTTCCAGATGAAGTGGACGGCCTACGAGCTGGAGCAGTTCCTGCGGGGCCTGGAGAAGCATGGCAAGGACTTTGGCAAGATTGCCAGCGAGCTCCTCACCAAGTCCTCCGGCGAGTGCGTGCAGATGTACTACTTCTGGAAGAAGCTCTGCGTGGACTACAAGGTCTCGCACCTGAAGATGGAGCCCGTGGTGGTGATCACTCCTGCCGTGGAGAAGCCCTATGTCTGCGAGATAGCCGACTGCTCAGCGAGCTTCAGTTCGAAGGCGGCGCTGCACGGTCATGTCCGCATTCACGCTTATGGTCGCAGCAACAGTAGCAACACcagcaatggcaacaacaacaccagcagcagcggcagcagcagtaataataacagcaacaataaccaGCATGGCACGGCCACTAGTGTGAATAGTAGCGGCGGCAACCCCAgtagcagcaacaccaacagcagcagcagcatcctcaACGGCAACATTAACGGCAGCAACTTTacctgcaacagcagcagcaataatcCCGCCAGCAATGCAGCAACtcctgcaggagcaggagcaggagcagcagcaacacatgCCGCATGCAATCCGAATCCTGGCACAACGACTGGAGCGGTCACCGCCATCTCGGCCACGTCCAAGCCGGAACAGGGAATTAACGCCATACCAGGTGCCGCCAAGGAGGGCGAGTTTCCCTGCAAGGTGTGCGGCAAGGTCTTCAATAAGGTGAAGAGTCGCAGTGCGCATATGAAAACCCATCGTGTCCAGGAGCCGGATCAGAAGCACCAGCAGCTCAATcaccaggcagcagcagcagcaggaggagcagctgcatcaGCTCTGGCCACCGTCGCCGCATCAAGCATCACCACTTCGTCGTAG
Protein Sequence: MCSASVGTEGSVTLQLRDANALEATTSSSSKTATSGGGAAAAAAGAGASSTNGAATASAATLENALTIGYPDPEMLADVLGTIQTASLKNHNTNSITASNGHGHGHGHGRHVPSSGGVSTAAAATSNSSNGIGIGIGGIISVEAPRKNRPKLSSPTRHGPQQCQTCCKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHAGGATTPTTTSQQSLSPTASSSGASSSSVGVATSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSSSSASASASISSLSSASSGIGLTAVSSPSSVGTVIATSSPAPTITLSDGMSLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTNQAPSQSRPRTWNMQLLNSAQNVTVTVEDNTELVAPSSSSPVEVKEEELSPQLVAAINPHLLNIVKLDKPVECNLCHRKFKNIPALNGHMRLHGGYYKKDPETKRSEKKDSSGPPLQTASIGVRALIEEKIISKRKDMTKGSFVVPAPPHSSGTTTTLRRSISDLESFLNPKSSSSGHTQTLNTGTGTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGQKQAKTLNLGSGTNTITITTNNVPTTTTMSALTALKAGGTISGISTATNTDPKDSTLIELLKRGTRIAVTSKKAQAQCQTTSGVLMTSSSTATQSMGTLTELTTIGGSSVQAVGRQIITNNNRTVIIPSDVQVVSTKSKLTSLSTLSSLVKSTVATTTSSSTNTSCSSGNLSLADGTPLSLTIAPSQDVSGGGGVPSGTGSVITSGGGGVYTVTYTSDGTDLFDDAEVYNVSDTEMLLQTVDSMELLHDDEEEPQIKSEHSEDFAMLSEAGDSAHTQLVKLEPESGQASGNSSSGGGGTGANTTPLPTFQQFHSKELIMQNSSQIQAIASMRPSGAGSGAGAGNGSGVLASPLHSPLAYPTPPSSHENMAQSSPFIEDAAAQFVDASNTFFGDKTDFSHIYFKTDEGQATIEQMNEHDNEKILKLKSVLEESSFDPSIKVEDLLNGTDDDTECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLTSEQQGENIIDLYYLPGLGLQSQMMPNSEDPLLSSSPREFGQQRQQMSSIQPLEQQLQQNGNLYQQQQQQEQQQQTQQLQEQQQPQQEPSQQQQQQQQYQQILLPQQTANQGESLPAVVQQQADFMLPLVGGHGFAQVSSGQAQYVDNGQGNMQGMQPLNSLLQPLLYQGGVTSNGIAAAGQEGLLSTDCQMNANQSQTSTLDAGLLFACGNTTTTTSNAATTTMGGNKSLLASGPLSGSVSNLQPLSNQTNSILKRRLRSSAPQETHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCSVRKQLGLSQGLFDAFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPSCRSPEEAVRDSPCAELMWNPEVQEDEKILMRYIDLSKSSAVPMGSHSEEVALHTLLKARGNSAAAVLTLLQTQSGAFQMKWTAYELEQFLRGLEKHGKDFGKIASELLTKSSGECVQMYYFWKKLCVDYKVSHLKMEPVVVITPAVEKPYVCEIADCSASFSSKAALHGHVRIHAYGRSNSSNTSNGNNNTSSSGSSSNNNSNNNQHGTATSVNSSGGNPSSSNTNSSSSILNGNINGSNFTCNSSSNNPASNAATPAGAGAGAAATHAACNPNPGTTTGAVTAISATSKPEQGINAIPGAAKEGEFPCKVCGKVFNKVKSRSAHMKTHRVQEPDQKHQQLNHQAAAAAGGAAASALATVAASSITTSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00590178;
90% Identity: iTF_00480106;
80% Identity: iTF_00480106;