Basic Information

Insect: Drosophila arawakana
Gene Symbol: -
Assembly: GCA_018151165.1
Location: JAECWX010000239.1:2393394-2395694[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0027 0.16 12.4 6.3 2 23 244 265 243 265 0.97

2 12 0.0017 0.1 13.0 2.3 1 23 271 296 271 296 0.94

3 12 1.4e-05 0.00081 19.6 1.4 1 23 303 328 303 328 0.97

4 12 0.0025 0.14 12.5 4.4 1 23 336 358 336 358 0.97

5 12 0.00056 0.032 14.5 2.4 3 23 367 387 365 387 0.98

6 12 0.00012 0.0069 16.6 0.1 1 23 393 415 393 415 0.98

7 12 0.35 20 5.7 6.8 1 23 421 444 421 444 0.97

8 12 7.5e-06 0.00043 20.4 4.3 1 23 450 472 450 472 0.97

9 12 0.00012 0.0066 16.7 2.1 1 23 478 500 478 500 0.99

10 12 5.8e-06 0.00033 20.8 0.4 2 23 578 600 577 600 0.96

11 12 6.9e-05 0.004 17.4 3.5 1 23 606 628 606 628 0.97

12 12 7.1e-05 0.0041 17.3 5.9 1 23 634 656 634 656 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0027	0.16	12.4	6.3	2	23	244	265	243	265	0.97
2	12	0.0017	0.1	13.0	2.3	1	23	271	296	271	296	0.94
3	12	1.4e-05	0.00081	19.6	1.4	1	23	303	328	303	328	0.97
4	12	0.0025	0.14	12.5	4.4	1	23	336	358	336	358	0.97
5	12	0.00056	0.032	14.5	2.4	3	23	367	387	365	387	0.98
6	12	0.00012	0.0069	16.6	0.1	1	23	393	415	393	415	0.98
7	12	0.35	20	5.7	6.8	1	23	421	444	421	444	0.97
8	12	7.5e-06	0.00043	20.4	4.3	1	23	450	472	450	472	0.97
9	12	0.00012	0.0066	16.7	2.1	1	23	478	500	478	500	0.99
10	12	5.8e-06	0.00033	20.8	0.4	2	23	578	600	577	600	0.96
11	12	6.9e-05	0.004	17.4	3.5	1	23	606	628	606	628	0.97
12	12	7.1e-05	0.0041	17.3	5.9	1	23	634	656	634	656	0.99

Sequence Information

Coding Sequence: ATGGACGACGAAACTCCAGCGTCAATACATTCGCTGTGTCGCACGTGTTTGACTAAATTGCAACGTGACGAAGCCTTCGATTTGTTTATTGTCCCGGGCCTGGCCAAGAAATTGTGTGTGTGCACTTCGCTGTCAGTGGAGCACCAGGATGGATACCCTAGGAATCTATGCAGCATTTGCTACAGCCGTCTCAACGAGTTGTTCGACTTTCAAAAACAGTGCGTGGACTCGGTGGAGAAGTTCAAGGATTTACTGTCCAAAAACTGCTTCAGCACGCTTCCGGAAGTGGAACCACCAATGGTTACCGCTCACGCGCTAGCGTCGGATGCAGTCGAGGAAGAAGATCACATTAACTTTGATCCACTGCTGAATACTAAAATGGAAATCGACAACGAAGCCGATGTTTTCAAAATGATTGAAGATGTCGACAAAGAATCGGAGGAAGTGGAGGATGTGGATAACTTGGAGGAAGCATTCAATGGCAGCGACAGCGACTATAACAACGACGAGGCAGACGAACCGAAGGACAGCAGCGAATCCGAGGATGATGAGATGCCGCTATCACGACTACGCAGCAGTAAGCGTACTCAAAAGACTAAAACTAAAAAGTCCGAAAGCGACAAAGAAGACGATTTACCCAGTTCAGAATCTCCGGAAAAAGCTGCTCCAAAAGCCAAACCGAAACGTAAGCGTATTCCAGCTTCTGAGCGTCATCTGCATGAAACTATCGAGTGTCACATCTGCCACCAGAGGTTTAAGAAAGCTGCCTGCTATGAGTTGCACATGAAGCGCCACAGCGATCAGCTGCCTTACCAGTGTGTGGCCAAGGACTGTCAGCGGGGATTCACAACCACCACAGGGCTAAAGCATCACATGGAGCACGCACACGCAGAGCTGTGTAAGCTACACAAGTGCTCTGTGGAGGGATGCGGCGAGTCCTTCTCCCAAACCCGCATGCTTACCAAGCATCTGCGCAAGGTGCACAACATTGCCAAGCCAGACATTCATCCCTGTTCAGAGTGCGAGAAAACTTTCCGTTGTCCCATGGCTCTCAAGAAGCACATGTATAAGCATACTGGAGAGGAGCTACCATTTGGCTGCACCATTTGCCAGAAACGCTTTCGTGTCCACACCGAACTCCGTGATCATCTTTTGCGGCATGCGGGAATCCGAAACTTTGTGTGCCCGTATTGTGGTGTGGGCAGAACCACCAAACAGGAGCTGGACAAGCATATACTGACACACACCAAGGAGAAGAAATTCATGTGTGATCAGTGCGATCACACCTCGCACAACAAGCAGTGCATGACGAAGCACATCAAGGTGGTGCACATGAACATTCGGAACTATATGTGTCAGTACTGCCAGAAATCCTTTGCCACCTCGTATCATCTGAAGAACCATGAGAAGTTGCACACGCGGGATGATTGCTTCGAGTGCAAAATCTGTGGCAGGAAATTCCTATTCGAGAGTAGACTAACCAAGCATTTGAGGACTCATGCTAAGCAAGGTGTAGGCAAGGACACAAAGGTGGAAACAGAGGGAGATGCAGCTAAGGATACAAAGGAACCGGAGAAGGCGCCAGACGTGCCAGTCAAGCCGAGGAATCCCCATCGTATTGAGATTGTCGATATGTCACAATTGGCTGGCACCTCGGTTAATCCAATTCCATCGGTATCTGTATCCTCCTGGTCGCCGCAGGTGGAGTTCACCAAAAACGAGGGTCAGCTCACGTGTCCGGACTGTGGACGGCGTTTCAATCATATTGGCAACATGAAGCTACACATCAGAGTTGTGCACGAAAAGATCAAGGACTACGCCTGCCGCTACTGTCCCAAGCGCTTCAGCCGAGCTCAGTATCTCCGTCATCATGAGTACACCCATACAGGGGAGAAGCCCTACGAGTGTAAAGTCTGCCAGAAGCATTTCCGACATGATGCGACTCTAAGAACGCACATGAAGTCGCATAACAAGCCACCAAAGGATCCAAGGAATCCCAGATATCATCCCAAAGAATCTTTGGAGCCAAGACTGCAGCTCAATACGGAACCAACAATGAACTACGAGGAATACCAGGATCCGGAGGCCGAACGAGAGGCGGCCACTGCTGAATTGGTGGCACACCAGCTAAACCGCGATGAAAGCGAGGGCAAGCCCAGATGGGGCGTGGCCAAAGGGCAGGAGGCACAGGAAGCTGCTTTTGAGCAATTGGAAAAGCTGAAGGTCCAGCAGCTTGAGCGGATTACCTACAGTATCTTAGAACCAGACGTTAGCAAGGACATACACAAAAATCATGTATAA
Protein Sequence: MDDETPASIHSLCRTCLTKLQRDEAFDLFIVPGLAKKLCVCTSLSVEHQDGYPRNLCSICYSRLNELFDFQKQCVDSVEKFKDLLSKNCFSTLPEVEPPMVTAHALASDAVEEEDHINFDPLLNTKMEIDNEADVFKMIEDVDKESEEVEDVDNLEEAFNGSDSDYNNDEADEPKDSSESEDDEMPLSRLRSSKRTQKTKTKKSESDKEDDLPSSESPEKAAPKAKPKRKRIPASERHLHETIECHICHQRFKKAACYELHMKRHSDQLPYQCVAKDCQRGFTTTTGLKHHMEHAHAELCKLHKCSVEGCGESFSQTRMLTKHLRKVHNIAKPDIHPCSECEKTFRCPMALKKHMYKHTGEELPFGCTICQKRFRVHTELRDHLLRHAGIRNFVCPYCGVGRTTKQELDKHILTHTKEKKFMCDQCDHTSHNKQCMTKHIKVVHMNIRNYMCQYCQKSFATSYHLKNHEKLHTRDDCFECKICGRKFLFESRLTKHLRTHAKQGVGKDTKVETEGDAAKDTKEPEKAPDVPVKPRNPHRIEIVDMSQLAGTSVNPIPSVSVSSWSPQVEFTKNEGQLTCPDCGRRFNHIGNMKLHIRVVHEKIKDYACRYCPKRFSRAQYLRHHEYTHTGEKPYECKVCQKHFRHDATLRTHMKSHNKPPKDPRNPRYHPKESLEPRLQLNTEPTMNYEEYQDPEAEREAATAELVAHQLNRDESEGKPRWGVAKGQEAQEAAFEQLEKLKVQQLERITYSILEPDVSKDIHKNHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00569134;
90% Identity: iTF_00569134; iTF_00471031;
80% Identity: -