Basic Information

Insect: Drosophila acutilabella
Gene Symbol: -
Assembly: GCA_035046005.1
Location: JAWNOK010000013.1:2531658-2533949[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0016 0.12 13.1 6.7 2 23 241 262 240 262 0.97

2 12 0.0017 0.13 13.0 2.3 1 23 268 293 268 293 0.94

3 12 1.4e-05 0.0011 19.6 1.4 1 23 300 325 300 325 0.97

4 12 0.0024 0.19 12.5 4.4 1 23 333 355 333 355 0.97

5 12 0.00055 0.042 14.5 2.4 3 23 364 384 362 384 0.98

6 12 0.00012 0.009 16.6 0.1 1 23 390 412 390 412 0.98

7 12 0.34 26 5.7 6.8 1 23 418 441 418 441 0.97

8 12 7.3e-06 0.00057 20.4 4.3 1 23 447 469 447 469 0.97

9 12 0.00011 0.0087 16.7 2.1 1 23 475 497 475 497 0.99

10 12 5.6e-06 0.00044 20.8 0.4 2 23 575 597 574 597 0.96

11 12 6.7e-05 0.0052 17.4 3.5 1 23 603 625 603 625 0.97

12 12 6.9e-05 0.0054 17.3 5.9 1 23 631 653 631 653 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0016	0.12	13.1	6.7	2	23	241	262	240	262	0.97
2	12	0.0017	0.13	13.0	2.3	1	23	268	293	268	293	0.94
3	12	1.4e-05	0.0011	19.6	1.4	1	23	300	325	300	325	0.97
4	12	0.0024	0.19	12.5	4.4	1	23	333	355	333	355	0.97
5	12	0.00055	0.042	14.5	2.4	3	23	364	384	362	384	0.98
6	12	0.00012	0.009	16.6	0.1	1	23	390	412	390	412	0.98
7	12	0.34	26	5.7	6.8	1	23	418	441	418	441	0.97
8	12	7.3e-06	0.00057	20.4	4.3	1	23	447	469	447	469	0.97
9	12	0.00011	0.0087	16.7	2.1	1	23	475	497	475	497	0.99
10	12	5.6e-06	0.00044	20.8	0.4	2	23	575	597	574	597	0.96
11	12	6.7e-05	0.0052	17.4	3.5	1	23	603	625	603	625	0.97
12	12	6.9e-05	0.0054	17.3	5.9	1	23	631	653	631	653	0.99

Sequence Information

Coding Sequence: ATGGACGAGGAAACTCCACCGTCAATACATTCGCTGTGTCGCACGTGTTTGACCAAATTGCAACGCGACGAAGCCttcgatttgtttattgtcCCGGGCCTGGCCaagaaattgtgtgtgtgcacttcACTGTCAGTGGAGCACCAGGATGGATACCCTAGGAATCTGTGTAGCATATGCTACAGCCGTCTCAACGAGTTGTTCGACTTTCAAAAACAGTGCGTGGACTCGGTGCAGAAGTTCAAGGATTTATTGTCCAAAAATTGCTTTAGCACGCTTCCGGAAGTGGTACCACCGATGGTTACCGCTCATGCGCTAGCGCCGGATGCAGTCGAGGAAGAAGATCACATTAACTTTGATCCACTGCTGAATACGAAAATGGAAATCGACAACGAAGCCGATGTTTTCAAAATGATTGAAGATGTCGACAAAGAATCGGAGGATGTGGATAACTTGGAGGAAGCATTCAATGGCAGCGACAGTGACTATAACAATGAGGAAGCAGACGAACCGAAGGACAGCAGCGAATCCGAGGATGATGAGATGCCTCTATCACGACTACGCAGCAGTAAGCGAGTTCCAAAGCCTAAAGCTAAAAAGTCGCAAAGCGACAATGATGAGGATTTACCCAGTTCAGAATCTCCAGAAAAAGCTGCTCCAAAAGCTAAACCGAAACGTAAGCGAATTCCAGCAGCTGAGCGACATCTCCACGAAACTATCGAGTGTCACATCTGCCACCAGAGGTTCAAGAAAGCTGCCTGCTATGAGCAGCACATGAAGCGTCACAGCGATCAGCTGCCTTACCAGTGTGTGGCCAAGGACTGTCAGCGGGGATTCACAACTACCACTGGACTAAAGCATCACATGGAGCACGCACATGCTGAGCTGTGTAAGCTACACAAGTGCTCAGTGGAGGGATGCGGCGAGTCCTTCTCCCAGACCCGCATGCTCACTAAGCATCTGCGCAAGGTGCACAACATTGCCAAGCCGGACATTCATCCCTGTTCAGAGTGCGAGAAAACCTTCCGTTGTCCCATGGCTCTCAAGAAGCACATGTATAAGCATACTGGAGAGGAGCTGCCCTTTGGCTGCACCATTTGCCAGAAACGCTTTCGTGTCCACACCGAACTTCGGGATCATCTTTTGCGCCATGCGGGAATCCGAAACTTTGTGTGCCCGTATTGTGGTGTGGGCAGAACTACCAAACAGGAGCTGGACAAGCATATATTGACACACACCAAGGAAAAGAAATTCATGTGTGATCAGTGCGATCACACCTCGCACAACAAGCAGTGCATGACGAAGCACATCAAGGTGGTGCACATGAATATTCGGAACTATATGTGTCAGTACTGCCAGAAATCCTTTGCCACCTCGTATCATCTGAAGAACCATGAGAAGCTGCACACGCGGGATGATTGCTTCGAGTGCAAAATCTGTGGCAGGAAATTCCTATTCGAGAGCCGACTAACCAAGCATTTGAGGACTCATGCCAAGCAAGGTGGCGGCAAGGATACAAAGGTGGAAACAGAGGGAGACGCAGCTAAGGATACAAAGGAGCCGGAGAAGGCGCCAGACGTCCCAGTCAAGCCGAGGAATCCCCATCGTATTGAGATTGTCGATATGTCACAGTTGGCTGGCACATCGGTTAATCCAATTCCATCGGTATCCGTATCCTCCTGGTCACCGCAGGAGGAGTTTACCAAAAACGAGGGTCAGCTCACGTGTCCGGACTGTGGACGGCGTTTTAATCACATTGGCAACATGAAGCTACACATCAGAGTTGTGCACGAAAAGATCAAGGACTATGCCTGCCGCTACTGTCCCAAGCGCTTCAGTCGGGCTCAGTATCTCCGTCATCATGAGTACACCCATACAGGGGAGAAGCCCTACGAGTGTAAAGTCTGCCAAAAGCATTTCCGACATGATGCGACTCTAAGAACGCATATGAAGTCTCACAACAAGCCACCAAAGGATCCAAGGAATCCCAGATATCATCCCAAAGAATCTTTGGAGCCAAGACTGCAGCTAAATACGGAACCAACGATGAACTACGAGGAATACCAAGATCCGGAGGCCGAGCGAGAGGCGGCCACTGCTGAATTGGTAGCCCACCAACTAAACCGCGATGAAGGCGAGGGCAAGCCCAGATGGGGTGTGGCTAAAGGGCAGGAGGCACAGGAAGCTGCCTTCGAGCAACTGGAAAAGCTAAAAGTCCAGCAGCTCGAGAGGATTACCTATAGTATCTTAGAACCAGAAGTTAGCAAGGATGTACACAAAAATCATGTATAA
Protein Sequence: MDEETPPSIHSLCRTCLTKLQRDEAFDLFIVPGLAKKLCVCTSLSVEHQDGYPRNLCSICYSRLNELFDFQKQCVDSVQKFKDLLSKNCFSTLPEVVPPMVTAHALAPDAVEEEDHINFDPLLNTKMEIDNEADVFKMIEDVDKESEDVDNLEEAFNGSDSDYNNEEADEPKDSSESEDDEMPLSRLRSSKRVPKPKAKKSQSDNDEDLPSSESPEKAAPKAKPKRKRIPAAERHLHETIECHICHQRFKKAACYEQHMKRHSDQLPYQCVAKDCQRGFTTTTGLKHHMEHAHAELCKLHKCSVEGCGESFSQTRMLTKHLRKVHNIAKPDIHPCSECEKTFRCPMALKKHMYKHTGEELPFGCTICQKRFRVHTELRDHLLRHAGIRNFVCPYCGVGRTTKQELDKHILTHTKEKKFMCDQCDHTSHNKQCMTKHIKVVHMNIRNYMCQYCQKSFATSYHLKNHEKLHTRDDCFECKICGRKFLFESRLTKHLRTHAKQGGGKDTKVETEGDAAKDTKEPEKAPDVPVKPRNPHRIEIVDMSQLAGTSVNPIPSVSVSSWSPQEEFTKNEGQLTCPDCGRRFNHIGNMKLHIRVVHEKIKDYACRYCPKRFSRAQYLRHHEYTHTGEKPYECKVCQKHFRHDATLRTHMKSHNKPPKDPRNPRYHPKESLEPRLQLNTEPTMNYEEYQDPEAEREAATAELVAHQLNRDEGEGKPRWGVAKGQEAQEAAFEQLEKLKVQQLERITYSILEPEVSKDVHKNHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00569134;
90% Identity: iTF_00478892;
80% Identity: -