Basic Information

Gene Symbol
Hr39
Assembly
GCA_018151165.1
Location
JAECWX010000440.1:216886-220638[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.3 2.4e+03 -2.6 8.2 52 168 251 360 192 380 0.64
2 3 3e-09 2.4e-05 23.8 0.0 1 25 447 471 447 480 0.93
3 3 3.7e-86 3e-82 277.1 2.6 81 408 562 857 548 857 0.87

Sequence Information

Coding Sequence
ATGTCCACTCCGTCCTCGACACGTGGACACAATGTCTCCGTGACGAACATTAAGTGTGAGCTGGACGAGTTGCCCACACCGAATGGGAATCTGGTGCCAGTTATAGCCAACTATAATAATCATCTAAACAATCACAATCATAATCATAATCACAATCTTAATCTCAATCATGGCGTGGGCAGTTTGCGTATTCCATTGGGTCTGCCCCATGCTGGCAAGGAGGATGAATCCGATTCGGATGCGGAATTGGCCAATATTGAGAATCTAAAGGTGCGACGACGGGCGGCCGACAAGAACGGGCCACGGCCCATGTCCTGGGAGGGTGAACTCAGTGAGCCCGAGACAGCTGGTGATGAGGAGCTCATGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATCCTTGAAACAAAACTATGCACCCAACAAACTGAAGCTGGCGCCAACACAAAGTGATCCAATAAATCTTAAGTATGAGCCCAGCACATCCACAACGCTCTGTGATCGGAGCAAGTCCAACAGTGGTGGCCATTTGCCGCTGCTACCCGCCAATCCCAGCCCTGACTCGGCCATACATTCCGTCTACACGCACAGCAGTCCATCGCAGTCGCCGCTAACATCGCGCCACGCCCCCTACACGCCCTCGCTGAGTCGAAACAACAGCGATGCGTCGCACAGCAGCTGCTACAGCTACAGTTCTGAATTTAGTCCCACTCATTCGCCCATTCAGGCGCGACATGCACCACCCGGTGGTGCTTCGCACTTTCCCAACAGCAGTGCCGTCAATGGTGCAGCACTGCATCATCACAGTGTGCTCTATCGTCCACTCAATGTGGATGCCACGACGACAACAACAGCGTCGTGCTCAACGACCCTTTCGGAGGCACAAAATCTGAGCATGGACGGAGCACTAGATGCCACGTCGACTGCTCTGCCAGCATCTCCGGCAGGTATTTCCCGGCAACAGTTGATCAACTCACCGTGTCCGATTTGTGGCGATAAAATCAGTGGCTTTCACTACGGCATCTTCTCGTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTACAGAATCGCAAGAATTATGTGTGTGTGCGTGGTGGTCCCTGCCAGGTGAGCATCTCCACGCGCAAAAAGTGTCCCGCCTGTCGGTTTGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCAATACGAGAGGATCGCACTCGTGGCGGTCGTTCTACCTATCAGTGCTCCTACACTTTGCCCAATTCGATGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGGCGGGGTGGGAGGAGGAGGGGGGGTAGGAGGCGGTGGTGGTGGCTCCAGTTCCCTGCCTGCCAGTCCGAGTCTGGGCGCATCAATCAAAACGGAGCAAGCGGAGACAATGAATCATCATTTAGCGCGAGCCTCCAGCATTCCAGCCCTTTTACAGGAAATCATGGATGTTGAACATCTCTGGCAGTACACCGATGCCGAATTGGCCCGCATCAATCAGCCTCTGTCCTCATTTGCCACCGGCGGTTCGTCGTCTAGTACGGGTAGCGGAAGTGGAAGTGGTAGCGGTAGCGGCTCAGGTGGACATCACACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCAGGTCTCTCATCCAATGGCGAGAATGCCAATCCCGATCTGATCGCTCATCTGTGCAATGTCGCCGATCATCGCCTCTACAAGATTGTGAAATGGTGTAAGAGTCTGCCGCTCTTCAAGAACATTTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAATTGCTGCTCTTTTCCTGCTGTTTTCGTTCCATTGATACGCCCGGCGAGATCAAGATGTCACAGGGTCGCAAGATAACGCTGGCACAGGCCAAAACCAATGGCTTACAGGCCTGCATCGAGCGCATGCTGAATCTGACGGATCATTTGCGACGTTTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTACTGCAATCCGATACAACGGAGCTGCAGGAGGCCGTAAAAGTGCGCGAGTGTCAGGAGAAAGCGCTGCAGGCATTGCAGGCCTACACGCTGGCCCATTATCCCGACACGCCGTCCAAGTTTGGTGAGCTACTGCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAGATGCTGACGATAAAGACGCGCGATGGTGCCGATTTCAATTTGTTGATGGAATTGCTGCGGGGAGAGCATTGA
Protein Sequence
MSTPSSTRGHNVSVTNIKCELDELPTPNGNLVPVIANYNNHLNNHNHNHNHNLNLNHGVGSLRIPLGLPHAGKEDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSEPETAGDEELMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLKQNYAPNKLKLAPTQSDPINLKYEPSTSTTLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPGGASHFPNSSAVNGAALHHHSVLYRPLNVDATTTTTASCSTTLSEAQNLSMDGALDATSTALPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGGVGGGGGVGGGGGGSSSLPASPSLGASIKTEQAETMNHHLARASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSTGSGSGSGSGSGSGGHHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00478776;
90% Identity
iTF_00478776;
80% Identity
iTF_00478776;