Dano018385.1
Basic Information
- Insect
- Drosophila anomelani
- Gene Symbol
- Aef1
- Assembly
- GCA_035045905.1
- Location
- JAWNOO010000165.1:12685181-12686222[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0096 52 4.3 0.1 22 48 196 222 188 226 0.86 2 4 3.4e-05 0.19 12.2 0.0 21 52 223 254 220 255 0.89 3 4 0.038 2.1e+02 2.4 0.1 21 48 251 278 249 282 0.85 4 4 0.0001 0.56 10.7 0.1 21 47 279 305 274 312 0.88
Sequence Information
- Coding Sequence
- ATGATGCATATCAAGAGCCTGCCCCATGCCCATGCCGCTGCCACGGCGATGAGCAGTAACTGTGACATCGTCATTGTGGCCACCCAGCCCCAAACTACGATTgctaacaataacaacaatgatACGGTCACCCAGGCTACGCATCCCAGCCAcatggcagcggcagcggcgactgttcagcagcagcagcaacagcagcagcatcaccagcagcagcagcaacaacaacagcagcagcagcagcccagtGGACCCCCCTCggcaccgccgccaccgccgacGGAATTGCCCTTGCCCTTCCAGATGCACCTGAGCGGGATCTCGACGGAGGCGCATAGCGCCGCTCAAGCAGCGGCCATGGCAGCTGCCCAGGCAGCGGCGGCCCAGGCGGCAGCggccgagcagcagcagccagcgcCACCGCAACAGTCTCAGCCACAGCACCTGGCGCATCTGACCTCGCACAGTCCAACGATGTCCAGCGATCACTATCTGGGCACCAACGGGCATGGCGAACATCCCGGCGAAGGTGGGCCTGGTAGTAATGGCAACGCCGGCAACGGAAGCGGAGGACCCCGCGAGCTGGAGAAACCCTTCCACTGTACCGTGTGCGATCGTCGCTTCCGGCAGCTGAGCACACTGACCAACCACGTGAAGATCCACACTGGCGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACCTTCCGTCAATCGTCGACGCTGACGAACCATCTGAAGATCCATACGGGCGAGAAGCCCTACAACTGCAACTACTGTCCTAAGCATTTCCGTCAGCTGAGCACCTTGGCCAACCACGTGAAGATCCACACTGGTGAAAAGCCCTTCGAGTGCGTCATCTGCAAGAAGCAGTTCCGCCAGTCCAGCACGCTCAACAACCACATAAAGATCCATGTGATGGACAAGGTCTACGTTCCTGTTAAGATCAaaacggaggaggaggaggggtgA
- Protein Sequence
- MMHIKSLPHAHAAATAMSSNCDIVIVATQPQTTIANNNNNDTVTQATHPSHMAAAAATVQQQQQQQQHHQQQQQQQQQQQQPSGPPSAPPPPPTELPLPFQMHLSGISTEAHSAAQAAAMAAAQAAAAQAAAAEQQQPAPPQQSQPQHLAHLTSHSPTMSSDHYLGTNGHGEHPGEGGPGSNGNAGNGSGGPRELEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEEEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00613017;
- 90% Identity
- iTF_00491728;
- 80% Identity
- iTF_00478218;