Basic Information

Insect: Drosophila anomalata
Gene Symbol: BPM1
Assembly: GCA_035046425.1
Location: JAWNNY010000735.1:518097-519335[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.3e-21 2e-18 66.7 0.1 3 99 19 117 17 125 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.3e-21	2e-18	66.7	0.1	3	99	19	117	17	125	0.88

Sequence Information

Coding Sequence: ATGGAGCGAAAGGACCAGGCACGGGCAGAAAACCTGCTGGGCAGACGCTACGGGCAGCTGTTCCACGGCGGCAAGTACACGGACTGTGTGTTTCACGTGTGCGAGGAGCAAGTCAAGTGCCACAAGCTTATACTGACCACCGCCAGTCCGGTCTTCGAGGCAATGTTCTACGGACCAATGCAGAACCACGACCCAGAACCCGAGATTGAGATCCACGACATCAGTGCTCCCATTTTCAAGGTCCTGGTGGAGTACATCTACACCGGATCGGTGGACTACAACAGCCTGGAGCTGGTCTCTTGCATTGAGCTCTACTATGCGGCGGAGAAGTATTTGCTGGAAGAACTCATCTCCGATTCCCTCATGGCCGTCACCTGCAAGCTTCGCTTCTCCAATATCCTGCCCGCTCTGGAGCTGAGCGTTTGCATGGGTCTGGATTCCCTGCTGGAGGTGTGCATGACCTTCTTTATGCGCTGCTGCGCCAACAACGGCCAGTATATTAATCACCTTAAGGAGCACTATGTGCACGTGTCCAAGGAGTGCGTCAAGGCCATCATTGCCGCCTGCAAAGAGCCGCACAAGCTGCTCATCTGGTACGTCTACGAGTGGACCCGGCAGGAGTGCGAGCAGCTGGGCCTAGATCCCGGAGATTCGGGCTTGGTGGCCCACGAATTGGGAGGCGAATCTACCGACTGGCCCGTGGCTGCAGAGCTGAAGTCTCCGTCTCCAACGATGACCCCCATATTGTCCATTGAACGTTGCTACTACAAGGCCTGCCGGCCATTTACGGTGGACGCCGACTGCCCAGTCTTTCGTCTGCGACTCAAGTGCTCTCGATTCATATCCCTGATGGGTTTGGTCCTGAACAGTCGGTTGACGCCCAACCGCTTGGGTCATGTGCAGGAGCTGGAGTACCGGGAATCCCTAAGACTGGACCTGTGTGAGTTGCCATCCGATAGCGAGGGTCCTCCAACCGAGGAGCCGGTGTGGAGCCACAAGGTGCAGAACCAGACCACAAAGTTCAACTGTGATCTGCACATCAGCTGGCGGCGCGAGGAGGCGTGTGTCCTCAATCCGGAGCTAACGTACGAGCTGCAGATTCGCTGGGATAGCAATGCCTATGGGGCAGAATATCCTTGCAGCCTGCAATCGTGCCAAGCGGACGGAATTCGATTCACGGACAGCGACAGCTTTAGCGGCAGTCTCGTCAAAGGACTACGCTACGCTAACCTGGTTTAG
Protein Sequence: MERKDQARAENLLGRRYGQLFHGGKYTDCVFHVCEEQVKCHKLILTTASPVFEAMFYGPMQNHDPEPEIEIHDISAPIFKVLVEYIYTGSVDYNSLELVSCIELYYAAEKYLLEELISDSLMAVTCKLRFSNILPALELSVCMGLDSLLEVCMTFFMRCCANNGQYINHLKEHYVHVSKECVKAIIAACKEPHKLLIWYVYEWTRQECEQLGLDPGDSGLVAHELGGESTDWPVAAELKSPSPTMTPILSIERCYYKACRPFTVDADCPVFRLRLKCSRFISLMGLVLNSRLTPNRLGHVQELEYRESLRLDLCELPSDSEGPPTEEPVWSHKVQNQTTKFNCDLHISWRREEACVLNPELTYELQIRWDSNAYGAEYPCSLQSCQADGIRFTDSDSFSGSLVKGLRYANLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00539056;
90% Identity: iTF_00615660; iTF_00546061; iTF_00504085; iTF_00615000; iTF_00476023; iTF_00539056; iTF_00481634; iTF_00580070; iTF_00550343; iTF_00566187; iTF_00488111;
80% Identity: -