Basic Information

Insect: Drosophila anceps
Gene Symbol: ush
Assembly: GCA_035045945.1
Location: JAWNON010000190.1:8855684-8876024[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0066 0.46 11.1 0.0 1 20 212 231 212 233 0.90

2 9 0.00028 0.02 15.4 0.8 1 23 288 310 288 310 0.98

3 9 0.051 3.6 8.3 1.0 2 21 356 375 356 376 0.92

4 9 0.049 3.5 8.3 2.9 2 21 753 772 752 773 0.93

5 9 0.0091 0.64 10.6 0.0 3 21 821 839 819 840 0.91

6 9 0.019 1.3 9.6 0.0 2 23 899 920 898 920 0.98

7 9 0.0038 0.27 11.8 1.3 1 23 926 948 926 948 0.99

8 9 0.0013 0.095 13.2 1.9 1 23 1003 1026 1003 1026 0.96

9 9 0.3 21 5.8 0.7 2 20 1133 1151 1132 1153 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0066	0.46	11.1	0.0	1	20	212	231	212	233	0.90
2	9	0.00028	0.02	15.4	0.8	1	23	288	310	288	310	0.98
3	9	0.051	3.6	8.3	1.0	2	21	356	375	356	376	0.92
4	9	0.049	3.5	8.3	2.9	2	21	753	772	752	773	0.93
5	9	0.0091	0.64	10.6	0.0	3	21	821	839	819	840	0.91
6	9	0.019	1.3	9.6	0.0	2	23	899	920	898	920	0.98
7	9	0.0038	0.27	11.8	1.3	1	23	926	948	926	948	0.99
8	9	0.0013	0.095	13.2	1.9	1	23	1003	1026	1003	1026	0.96
9	9	0.3	21	5.8	0.7	2	20	1133	1151	1132	1153	0.91

Sequence Information

Coding Sequence: ATGGCAAACGAGATAATCGTCATTAAAGgcagcaagaacagcaacaacagcaatagcagcagcaaagGTGATTGTTCCGAGACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGATTTGGGTGCACACGAGCTGAGCGAggagaaacagcagcaacagctggagGAGCAACCCGAGGACGATCAGCTAGAACAGCAAGCTAGCAACGCCTCTGAGCAGCTCGAGGAGACCGACATGGATCAGGAAATGGTCGAGGAGGAGCAGACAGCGGCCCAGGAGGCCAgtgcacagcaacaaaaggtGGCCGACAGCTCGACGACTCCGCCGCGTAGTCCCACGCCCCCTGAGCTGGTGCCCAAGCTGGAGCGTGCCGATTCGCCGGCAACGCCGCCTTCAGTGGCAGCCACGCCCAGTCCGCCACCAACGCCCACGCCGCCGTTGGTGCTGCCCAAGCTGCGCCTCAATGCACTGCTCGCTTCCGATCCGGCTCTGAAACCCGATGCCAAGGAACTTAATCTCGAGCCACGTTTGCTCGGTCCGCCGCCACAGCTAGCAAAgcccgagcagcagcagcagagtttGCCCGATCCTAGCAGCCTAGTGGAGCCGCTGCTCAAGCCGGCGCGTTTCATGTGCTTGCCCTGCGGCATAGCCTTCAGCTCGCCCTCAACGCTGGAGGCGCACCAGGCCTACTATTGCTCGCATCGCAACAAGGATGCCGACGAGGAGTCGACTGCCGGCGacaaagcagcagccgcagctggtGGCGGCGCCAATtcaaatgccaacagcagctccagcgGCGGCAGCTCCGGCTCCGAGCCGCCCGCCAAGGTGGCGCGCACGGGCAAGCAATACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAATCGGCATATGCGCATGCATCAGACCTCGCCCGCCGCTCCCACTCTGAACAGCCTGTCCGGTCTGGCGGCCAATGGtgtagctgctgccgctgccgccgccgccgccgctgcggcCAGTGCTCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATACGCTTCAATAACATCAAGACCTATCGCGCCCATAAGCAGCACTACTGCAGCTCGCGTCGCAGCGATGGCCAGCTGACGCCCAAGCCCGAGGCaaacgccaacagcagcacgGCAGGCTCTGCAGTGGGAGTTGCTAGCGCTGCGGTCAAGCACAGCGGCGCTCACAGTCCTCAGACGCGCAATAAGACGCCCACGCCTGCAAtggtcgctgctgctgctgcggctgctgctgctgcagccgccgccTCGCTGCAGGTGGCACCGCCGCAACCCTTCCTGGCGCTGCCCACGAATCCCATCATTATAGTGCCCTGTTCGCTAATACGCGCCGCCAGCCTCATACCTGGACCACTCACCACCTCCACTTCAGGCATTGTCAATCCAGAGTCCACATGCTTTACACTTGACAATGGAGCACTCAAGCCGCTGGCCACGGCGCTCAACATAAATGCGCTGGCAGggaatgccacgcccacgccaacATCCACACCCATGCCCAGCAACAATCAGCTGAGCATGCCCGCATTGGAACCAGAGCGTCCCAGTGCCAGCAGCGTCCTGGAGGCGGAGTGCAAGAGCAGTCCGCCAGAGCCCAAGCGCAAGGAAGCGAGCGGCATGCGCGACACCACGCCCTTGGACTTATCGCTGCGTCGTTCGCCCATTTCtccgctgctgcagcgccagcGTCTGATGGAGGAAGCGTTGCTCAGCGCCGGCAAGGAGAACATGGAGAGCAGTGGCCGTACAGCTGGCAGCGTTACACCGGAACAGATTGTGTGCGCACCGTCGCTGCCTAGCAGCCCCTCTATGAGTCCCTCGCCCAAGCGACGTGCGATCAGTCCACGCAGCTCGGGCGCGGGTAGCGCTGCGTCCATGTCGCCACCAGCTTTGACAGTGCCTCATCTGCTGGACAATCTGCAGCCATTGCGCTCAATGCTGCCCGCCGACTTTGCACTATCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCGCTCAAGttggcagcagccgctgcagcagctgtggcgGGAAGCAGCAGTGCCGAGCTGGCCAGCAAGCTGGGCTTCAGCCCGGCAACTGGCGCTGTTCCTCCTCCGACTGTGGGGAACGTAGCACCCAATACGCCCAACAGCCAGCCGCAGATCTATGTGAAGCAGGGCGTCTCCAAATGCAAGGAGTGCAACATAGTTTTCTGCAAGTACGAAAACTATCTGGCACACAAGCAGCACTACTGCTCCGCTCGCAACCAGGACACAGGTGCGGATGGTGACTCCAAGAACGCTGTAACACCGCCCGCCGCTGTGGGCCCAGGCGTGCCTGCTGGCGCCTCCTCGTTGGAGACCACGCCCGTGGCCTACCAGCAACTGATCTGCGCCGCCTGTGGCATTAAGTACACCTCGCTGGATAATCTACGCGCACATCAGAACTACTATTGTCCCAAGGGTGGAGCGGCAGCCACGCCAGCCGAGGCAGCTACAccacagctgccgctgcccaaGGAGAAGTGCGTCAAGTGCAAGACGCTGCATGAACACGGCCAGCCCTGTCCTGCAcccccagccacgccccagcTGGCGCCGGCCACTGTGGCGAACAGCGTCAACAAGTGTCCCGTCTGTGGTGTAATCAGTCCCACTGCTGCACTGGCCCGCAAGCACATGGAAATGCATGGCACGGTCAAGGCATTCCGTTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGTGGCATGCGCACCCACATACGCACCCACTTCGATAAGAAGACCAGCGATGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGATAcggcagctgcggcagcaccGCCACCCCCCGCCATGGGCTTAGACCTGCCCGCTGTGACAGCGACCcaggagcagctggagcagcatgCGGCACAGATCTTCAACTGCGATCACTGCAACTATGCCTCCACCTACAAGGGCAATGTGCTACGTCATATGAAACTGTTGCATCCACACGTGGCAATTAGCTCGCCTTCCATATCACCCGAGTCCCGTGAACAGGATACCAATACCCATGCCCTGCCCGAGGTAGCTCTGGTAAATGGAGAACGTGAGGCGGCCAGTTTCCACATTAAGTCGGAGCCCTTGGAGCCACCTGTGGCCACATTGAGTCTGGTGCATGATAACAACAATTCGCCCATTGGCACACCGCATACGCACATCAAAGCCGAGCCACTGGACATGGGCCTAGAGTTAACCGCAGCTCCACTGCCTCCACCCATGGCCAATTCGCCGCTGGGACCGAGCGCTGCGGAAGCTATGAAGAAATACTGTTCCACCTGCGACATATCATTCAACTATGTGAAGACATTCTTGGCGCACAAACAGTTCTACTGCAAGAGCAAGCTGCATCGACCGGAAGCCAGCGATAGCCCCAGTCCCACTGTGGGCGTTGGTGGCACCGCCATGCCGCTGCAGTCGCCCagcgagctgctgttgctgcagaaGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MANEIIVIKGSKNSNNSNSSSKGDCSETTEEMTVDSRDSKDLGAHELSEEKQQQQLEEQPEDDQLEQQASNASEQLEETDMDQEMVEEEQTAAQEASAQQQKVADSSTTPPRSPTPPELVPKLERADSPATPPSVAATPSPPPTPTPPLVLPKLRLNALLASDPALKPDAKELNLEPRLLGPPPQLAKPEQQQQSLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEESTAGDKAAAAAGGGANSNANSSSSGGSSGSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVAAAAAAAAAAAASALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEANANSSTAGSAVGVASAAVKHSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNATPTPTSTPMPSNNQLSMPALEPERPSASSVLEAECKSSPPEPKRKEASGMRDTTPLDLSLRRSPISPLLQRQRLMEEALLSAGKENMESSGRTAGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSAASMSPPALTVPHLLDNLQPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSSAELASKLGFSPATGAVPPPTVGNVAPNTPNSQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDTGADGDSKNAVTPPAAVGPGVPAGASSLETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHEHGQPCPAPPATPQLAPATVANSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDTAAAAAPPPPAMGLDLPAVTATQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDTNTHALPEVALVNGEREAASFHIKSEPLEPPVATLSLVHDNNNSPIGTPHTHIKAEPLDMGLELTAAPLPPPMANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEASDSPSPTVGVGGTAMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -