Basic Information

Insect: Drosophila anceps
Gene Symbol: Trerf1
Assembly: GCA_035045945.1
Location: JAWNON010000140.1:4063356-4073289[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00014 0.0097 16.4 0.2 2 23 333 354 332 354 0.97

2 6 4.3e-06 0.0003 21.1 1.3 1 23 360 382 360 382 0.98

3 6 0.00041 0.029 14.9 2.5 1 23 388 412 388 413 0.94

4 6 0.00071 0.05 14.1 0.8 2 23 680 701 679 701 0.97

5 6 0.002 0.14 12.7 0.1 1 23 1832 1856 1832 1856 0.98

6 6 9.5e-05 0.0067 16.9 0.8 1 23 2008 2030 2008 2030 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00014	0.0097	16.4	0.2	2	23	333	354	332	354	0.97
2	6	4.3e-06	0.0003	21.1	1.3	1	23	360	382	360	382	0.98
3	6	0.00041	0.029	14.9	2.5	1	23	388	412	388	413	0.94
4	6	0.00071	0.05	14.1	0.8	2	23	680	701	679	701	0.97
5	6	0.002	0.14	12.7	0.1	1	23	1832	1856	1832	1856	0.98
6	6	9.5e-05	0.0067	16.9	0.8	1	23	2008	2030	2008	2030	0.98

Sequence Information

Coding Sequence: ATGTGCAACGCATCTGTGGGCAGCGAGGGTTCCGTAACACTGCAACTAAGAGATGCGAGTGCTTTGGAGGCAGCCGCCAGCAGCACaagtacagcaacaacaacaactgcagcaacagcagcaacatcgtcATCAGGCCAAGCCAGCCAAGCGAATGCGTCAGGACTAACGTCAGCATTAGAGAATGCGCTGACTATTGGCTATCCGGATCCGGACATGTTAGCAGATGTCTTGGGCACCATACAGACAGCCTCTCTTAAGAACAAACAAAGcagcaacaccaccaccaacaccaataccaacagcaatagcaacagcatcagcaacagcaaacgaaGCATTAATGgtagcagcagccgaagcaaCTGCACTACTGCTCCAACAATTTTGAACAATACGATTGGAGCAACGAGCTCTGGCGTTCGCCTGAACAGTCCCAATAGGATAACAATTACGCGACGCAGCGCTAGCAATAAGATTAGCGTACAAACTGTGAGCGCTTCAACAAACACAACCATTAGTAGCATTGGTGGCAGCAAGACCAACTACATTAAGAACTGTCTaatacgcagcagcagctgcagcaacacgGCCACCAATGTCACAACGCTGGCACAGATtatgagcaacagcagcaccagcagcgccGCCAGTTTACTCAGTCAgcacaacaataatagcaactgcagcaacagcagcaactttaGCAACGCCTCGTCTGTGGGTAGCAGCATTAGTATtaacagcaccaccagcagcagcaccaccagcagtcACAGTagcagccatagccatagcaacagcaacagcaacgacagcaacagcagcagcggtcaCAGCCTAAGTTTCAAGAGCAACGGCCGACATGTTGCTAGCAtagtaacaacagcagcatccacGAACACCACTGCAACTGGCATTGGCATAATCACTGTCGACCACGCTCCCCGAAAGAGCCGACCCAAGTTATCCTCACCCACGCGTCACGGCCCCCAACAGTGTCAGaTTTGTAGCAAGATCTTTGGGAATGCCTCGGCACTAGCCAAGCACAAACTGACGCACAGCGACGAACGGAAATATATTTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGGAACAAGAAACCTTACGAATGTAAGGCGGAAGGCTGCGGAAAGTCCTATTGTGATGCCCGCTCTCTTCGCCGACATTCGGAAAATCACCATGGAGGCGTGGCCACTCCGAATAACAACTCGCTCTCGCCAACGACTAGCACCAACTGCGGCAGCGTGAGCAGtggcagtagtagcagcagcagcagtgtgggcgtggccaccAACTCGCTTAGCCTGTCGCCGGCTACGGCGAGTGGTGATGCCAGCTCACCAGACGGTGCCACCTGCATTCGCACCTACATTTCCACAGGCAGCACAGTGGTGGACGCAGCCACTGGCATTGCGCTATCCGACGAGCAGATCAAGGCCATGAATTTGCCCATTAAAACTGGCGTTACATTGTTGTCGCCCACCACATCGACATCGTCGAACGCATCGTCCACAGCATCCTCGGCATGCTCCACATCGGGCAGCAACAccagcggcaatggcaacggcaacggcaacggcaatggcaatgctaTTGTTACTAGCTCACCCACAATTACGCTTAGCGATGGCACCACGCTCGAGGGCGATGGATTGACGCGCGAGCAACTCGATCTCATAAGCAAGATCATGCAGCAGACAAAGCAGACCAGTGCACAGGTCACTGTCTCCTCTCCCACCAGCGTCAGCTCCTACAAAATCAATACAGAGACAACGCAAGTTTCGTCGCGACCGCGCACCTGGAACATGCAATTGcTTAATAATGCACAAAACGTGACAGTAACTGTGGAGGATGGCACAGAGTTGGCTGGCTCGACTTCAGTTTCACCCGATGAGGTCAAGGACGATGAGATGAGCCAGCAGTTGGTGGCCGCCATTAATCCCCATCTGCTCAACATTGTTAAGATCGACAAGCCGGTCGAGTGCAATCTATGTCATCGCAAATTCAAGAATATACCCGCCCTTAATGGGCACATGCGTCTGCATGGCGGATACTTCAAAAAGGATCCGGAAACTAAACGCAGTGAGAAGAAGGACTCGAACGGACCTCCTTTACAGACAGCCAGCATTGGAGTGCGCGCCCTCATCGAGGAGAAGATCATCAGCAAGCGGAAGGACATAAATAAGGGCGCCTTCGTGGTGCCTGCTCCACCGAGTACCACAGGCAACAGCGGAGGCGTAGGagcctgcagcagcaacagcaacacactgCGACGCTCGATAAGTGACCTGGAGAGTTTTCTCAATCCGaagtgcagcagcaccagcttGAGTCAGGCACTctccaccagcagcagcaccaccacagCGGTGCTGCCGGCAGCGACCACAATCAAGAGCAGCAATGGGCTAAGCATACAGCAGATTGGTCTGCCGCAAAGCATCGAAATCTTCAGCGGAGGTCACAGGCAGCCAAAAACCCTTAGTTTAGGCAGTGGTGCCAATACAATAACCATAACCACCAATAACGTGCCTACCACAACCACCATGAGCGCCCTAACGGCATTGAAGGGCGGCGGCACCATCAATGGCATCTCCAGCAATGTGGATCCCAAGGACTCGACATTAATTGAGCTGCTTAAGCGTGGCACGCGTATCGCCGTCGCCTCCAAGAAGACTCACTTGCAAACGCAGAGCAGCACAAATCTGTTGCTGAGCAATGTGACGGGCACGGAGCTCACAACCATTGGCAGCAGCGTCCAGACAGCTGGCCGACAGATAATAACCAACAACAATCGCACAGTCATCATACCCTCGGATGTGCATGTGGTGTCCACTAAAAGTAAGCTCATCTCGACACAAGCCATCGCagccaacgacaacagcaacatcaacagcagcagcaacaatgcaacaTGTTCGACAAGCAGCATCTCTTTGCCGGATGGCACTCCGCTCTCAGTGGCCATTGCGAATAGCCAAGAGAATTTGGGCGTTAGCGAGGCAAGTAGCATTACGGGCGCCGGCGGTGTTTACACTGTGACCTACACTAGCGATGCGGATGCATCGGACCTCTTCGACGACGCTGAGGTCTACAATGTCTCGGATACGGAAATGCTACTGCAAACGGTGGATACCATGGAATTACTcaatgatgatgaggatgtgGTGCACAAGAGCGAACATTCCGAGGACTTTTCGCTGCTCAGCGAGGCCGGCGAAACTGTGCATACGCAGCTGGTCAAGACGGAGCCGGGACTACCTAGCACAACTAACAGCATAAATAAGACGACGCCGTTGCCCACCTTCCAGCAATTCCATTCCAAAGAGATTATCATGCAGAACAGTTCGCAAATTCAAGCCATTGCCAACATGCGTAACGGCAGCAATCTGGGCGTGCTCGCCTCACCCTTACATTCGCCAATAGCCTATCCGACGCCGCCGTCCAGCCACGAGAATATGGCACAGTCCTCACCTTTCATAGAGGATGCTGCGGCTCAGTTTGTGGACTCCAGTCACACATTCTTTGGCGACAAGACAGACTTCTCGCACGTCTATTTTAAAACAGACGAGGGCGATTCCATGCAGCAACTCACTGAGAACGACAACGAGAAGATACTCAAACTGAAGACGGTGCTTGAGGAGAGCAGCTTCGATCCGTCTATCAAAGTGGAAGATCTGTTGAGTAGCACTGAAGACGATGCTGAGTGCGATTTGCGCGAGTTTGCTGAGACAAATCTCTCGTTCCTGGATGAGGATCAGGAGTTCCTGAATGACTCACGAAATGCCACCTCTCCGTTGTCCGAATCCTTTTTTACCAGTGGCATCGGTTCGGCCGAGGATGTCAAACAAGTGCTGCGTGAGGTGTTGCCCGAGGAAAATATACAATTGCAGttgagcagcgagcagcaggGCGAGAACATCATTGATCTTTACTATTTGCCCGGTCTTGGCCTGCAATCCCAAATGATGCCCAACTCCGACGACCCGCTGTTGTCGTCCTCGCCACGAGAATTCGGCCAACAGCGTCAAGTTCTGCATGCAACATCTGCGACTACGACTGCACAACCTATCGAACAGTTGCAGTCTACGACTGTGCTTTAcgaccaacagcagcagcaacagcaacaacaattgcaactgcaattgcaaatgcaaccccagcatcagcaacagtcacaggaacagcaacaagcgcaagaacagcaacagcagcagcagcaacatcagcagcaacagcagcagcaacagcagcagcaacagcaacagctagaagctcaacagcaacagctgcaattgcCTCAGCTACCTGCCATGCAAActgaacaacagcagcaacaaactgaTTTTGTGCTCACTAACTTTACGCCCGTAAACTGTCAACCTCAATATATGGATGCCAATCAGCAGCCGATGATGCTGCAGCCATTGAATAGCCTGCTGCAGCCAATACTttacggcaacagcagcactggGAATAATAAGCCCGCATTTAGCACGCTTCTCAACGGCAATACGGTTCAGGCAACAGCACTCGATGCGAGCCTGCTCTTTGCCTGCGATGACTCCAAAAATAACTGCAACAAACCAATGCTAGCCGCTTTACCCGCAGCAATTCCGACGCCCGTAGTTACTGCTGCACCAAGTGTTGCTAATCTGCAGCCGTTGTCCAATCAAACGAATTCCATACTAAAGCGTCGACTGCGATCCAATGGAGCGCAGGATGTGCACAAGTTTTCGAAATTCCATACACTTTCGCCGCATCGTTCGAAGCTGCGCAAGCCATCGCGAACCCACTACACCCCTGCCCCAATACTCAATCCGGATCGCAAGGGCACTGGGCTCTACTGCAATGTGCGCAAACAGCTTGGCCAGGGCATGTTCGACGTATTTGACGATGACTTTGGCGATCCTGTGGGCTTGGTGGACTTCTGCGACGAGTCGAAGGTGAATCTTGGCTCCACCTATCAAGCGCAGATCCCAGCATGCAAGGCGCAAGACGAATCTCTTAAGGAACCCATGTGCGCCGACCTCATGTGGGATCCAAGTGTCCAGTTGGACGATAAGATACTGATGCGTTATATAGATCTCAGCAAATCATCGGCCGTACCCATGGGCAGCCATTCCGAGGAGGTAGCCTTACAGACGCTACTCGACGCAAAGGGCAACTCGGCGGCAGCGGTGCTTACACTACTGCAGATGCAGTCTAGCGCATTCCAAATGAAGTGGACTGCCTACGAGCTGGAGCAATTTCTACGTGGCCTCGAAAAGCATGGCAAAGATTTTGGCAAAATCGCAAGCGAGCTTCATACAAAGACTTCAGGCGAATGCGTgcaaatgtattatttttggaaGAAACTCTGTGTGGACTACAAGGTATCGCACCTTAAAATGGAGCCAGTTCCTGCGAGCATCCCAACGGTGGAGCAGAAGCCCTACGTTTGCGAGATTGCCGACTGCTCGGCGAGCTTCAGTTCTAAGGCGGCGCTGCATGGTCATGTTCGCATACACGCTTATGGTAgaaatgccagcaacaataatagcaacaacagcaacaacaacagcaacaaccagcaTGCCACGGCAACTagtgccaacaacaaccataattccagcaacagcaacaacaacaacaacaccaatagCAACAACGCATGCACACCCCTGACTAGCAGCAGTCAACAGactagcaacagcaacaacaacaatgcaacaacaaccataacGCACACTAATGGCAATAACAACACCAccgcgaacaacaacaataatatgaacaacaacaacagcatcgcTGGCATTTCCACAAACCCAACGATGCTctcagtagcaacaacagcaatagcaacagctgccgctgcagccgcaacaacagctgttgcagcagtaGCCACATCAACAGCATCGACAGCAATGAAagacagtagcaacagcaacaattccAACATACCCAAGGACAGTGAATTTCCCTGCAAGGTGTGCGGCAAAGTCTTCAATAAGGTGAAGAGCCGCAGCGCACATATGAAAACGCATCGAGTACAAGAAGCGGAACAACTAGCCAATTCCAAACAGCAATCATCcacacttgttgttgctgtcgcagcaacagcttcagcagcagccgcagcagcagcaacatcctcagcagcagcaacagcaatggccaCAGCAATTTCCTAG
Protein Sequence: MCNASVGSEGSVTLQLRDASALEAAASSTSTATTTTAATAATSSSGQASQANASGLTSALENALTIGYPDPDMLADVLGTIQTASLKNKQSSNTTTNTNTNSNSNSISNSKRSINGSSSRSNCTTAPTILNNTIGATSSGVRLNSPNRITITRRSASNKISVQTVSASTNTTISSIGGSKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSNASSVGSSISINSTTSSSTTSSHSSSHSHSNSNSNDSNSSSGHSLSFKSNGRHVASIVTTAASTNTTATGIGIITVDHAPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKAEGCGKSYCDARSLRRHSENHHGGVATPNNNSLSPTTSTNCGSVSSGSSSSSSSVGVATNSLSLSPATASGDASSPDGATCIRTYISTGSTVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSACSTSGSNTSGNGNGNGNGNGNAIVTSSPTITLSDGTTLEGDGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTETTQVSSRPRTWNMQLLNNAQNVTVTVEDGTELAGSTSVSPDEVKDDEMSQQLVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETKRSEKKDSNGPPLQTASIGVRALIEEKIISKRKDINKGAFVVPAPPSTTGNSGGVGACSSNSNTLRRSISDLESFLNPKCSSTSLSQALSTSSSTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGHRQPKTLSLGSGANTITITTNNVPTTTTMSALTALKGGGTINGISSNVDPKDSTLIELLKRGTRIAVASKKTHLQTQSSTNLLLSNVTGTELTTIGSSVQTAGRQIITNNNRTVIIPSDVHVVSTKSKLISTQAIAANDNSNINSSSNNATCSTSSISLPDGTPLSVAIANSQENLGVSEASSITGAGGVYTVTYTSDADASDLFDDAEVYNVSDTEMLLQTVDTMELLNDDEDVVHKSEHSEDFSLLSEAGETVHTQLVKTEPGLPSTTNSINKTTPLPTFQQFHSKEIIMQNSSQIQAIANMRNGSNLGVLASPLHSPIAYPTPPSSHENMAQSSPFIEDAAAQFVDSSHTFFGDKTDFSHVYFKTDEGDSMQQLTENDNEKILKLKTVLEESSFDPSIKVEDLLSSTEDDAECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPEENIQLQLSSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQVLHATSATTTAQPIEQLQSTTVLYDQQQQQQQQQLQLQLQMQPQHQQQSQEQQQAQEQQQQQQQHQQQQQQQQQQQQQQLEAQQQQLQLPQLPAMQTEQQQQQTDFVLTNFTPVNCQPQYMDANQQPMMLQPLNSLLQPILYGNSSTGNNKPAFSTLLNGNTVQATALDASLLFACDDSKNNCNKPMLAALPAAIPTPVVTAAPSVANLQPLSNQTNSILKRRLRSNGAQDVHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGMFDVFDDDFGDPVGLVDFCDESKVNLGSTYQAQIPACKAQDESLKEPMCADLMWDPSVQLDDKILMRYIDLSKSSAVPMGSHSEEVALQTLLDAKGNSAAAVLTLLQMQSSAFQMKWTAYELEQFLRGLEKHGKDFGKIASELHTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVPASIPTVEQKPYVCEIADCSASFSSKAALHGHVRIHAYGRNASNNNSNNSNNNSNNQHATATSANNNHNSSNSNNNNNTNSNNACTPLTSSSQQTSNSNNNNATTTITHTNGNNNTTANNNNNMNNNNSIAGISTNPTMLSVATTAIATAAAAAATTAVAAVATSTASTAMKDSSNSNNSNIPKDSEFPCKVCGKVFNKVKSRSAHMKTHRVQEAEQLANSKQQSSTLVVAVAATASAAAAAAATSSAAATAMATAIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00573254;
90% Identity: iTF_00476558; iTF_00573254; iTF_00573548; iTF_00493896; iTF_00493580; iTF_00559720; iTF_00559425; iTF_00516500; iTF_00516191; iTF_00545172; iTF_00545472; iTF_00544724; iTF_00544427; iTF_00540601; iTF_00540304; iTF_00599518; iTF_00599816;
80% Identity: iTF_00476558;