Basic Information

Insect: Drosophila ananassae
Gene Symbol: RREB1
Assembly: GCA_017639315.1
Location: CM029945.1:7838995-7845123[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0048 0.37 11.3 0.6 1 21 236 256 236 258 0.96

2 12 0.00027 0.021 15.2 0.2 1 23 268 290 268 290 0.98

3 12 1.7 1.3e+02 3.2 3.7 2 19 547 564 547 566 0.97

4 12 0.0069 0.53 10.8 0.1 1 23 716 738 716 738 0.97

5 12 1e-05 0.00077 19.7 0.7 1 23 748 770 748 770 0.99

6 12 0.00068 0.052 13.9 2.0 1 23 776 799 776 799 0.97

7 12 0.0024 0.19 12.2 2.0 1 23 1071 1094 1071 1094 0.95

8 12 7.1e-05 0.0054 17.0 0.3 2 23 1458 1479 1457 1479 0.97

9 12 0.12 9.1 6.9 6.3 1 23 1485 1508 1485 1508 0.97

10 12 1.4 1e+02 3.5 2.1 1 23 1630 1653 1630 1653 0.91

11 12 0.0069 0.53 10.8 0.5 3 23 1720 1740 1718 1740 0.96

12 12 0.0052 0.4 11.1 5.7 1 23 1746 1768 1746 1768 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0048	0.37	11.3	0.6	1	21	236	256	236	258	0.96
2	12	0.00027	0.021	15.2	0.2	1	23	268	290	268	290	0.98
3	12	1.7	1.3e+02	3.2	3.7	2	19	547	564	547	566	0.97
4	12	0.0069	0.53	10.8	0.1	1	23	716	738	716	738	0.97
5	12	1e-05	0.00077	19.7	0.7	1	23	748	770	748	770	0.99
6	12	0.00068	0.052	13.9	2.0	1	23	776	799	776	799	0.97
7	12	0.0024	0.19	12.2	2.0	1	23	1071	1094	1071	1094	0.95
8	12	7.1e-05	0.0054	17.0	0.3	2	23	1458	1479	1457	1479	0.97
9	12	0.12	9.1	6.9	6.3	1	23	1485	1508	1485	1508	0.97
10	12	1.4	1e+02	3.5	2.1	1	23	1630	1653	1630	1653	0.91
11	12	0.0069	0.53	10.8	0.5	3	23	1720	1740	1718	1740	0.96
12	12	0.0052	0.4	11.1	5.7	1	23	1746	1768	1746	1768	0.99

Sequence Information

Coding Sequence: ATGCTGGCAGCACAGCAGCAGCAGCAGCAGCACAATACCAGCAACAACACCAACACAAACACCACAGAGAACGAGATGGAGCGCCAGAGGCGGGACTCCACCACCTCGGAATCCTCGCTGGAGCACCTGGACTTGGGACGCACGCCCAAAAAGCTCAGCGCAGTCAGCAGCGGCGGCGGCGTCGGCGGCAGCGGCAGTCTGGTGCTGCAGCCGACGTCGACGCCACACGAAGTGGCGACAGCGACGTCGCGCAAACGTAAACTGCGCCAGCTCCAACATCACCACCAGGACCTGCTCAGCGACGAGGACGAGGAGGAGGAGGAAGCATCAGCGCCCGGGGCCCGCCCCCACGGTCGCCAAAAGCAGCGACGCAACGCCAGCATCGTGCTGGACGGCAGCGGCAGCGACGCCAGTTCGCTGCGCAAGAAGTTCCGTTTAAATCGCTCGGCAGCTGCGGTGGCGGCTGTCTCCAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGGATCCGGTGGATCTTCGCCGCAAGGTGGCCTGTGCCTCTCCAGCGGCGAGTCCGGCATCGGGGCGGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCAGTGCCACGCCCCACGAGTTCACCAATCACATTCGGTGCCACAACTACGCCAACGGGGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCCGCCTCATCCCTGGACCGACACGTGCTGGTGCACACCGGCGAGCGTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCCAACCACAACCACAAGGACATGGAGCTGGACCTGGAGCTGGAGGAGGAGGTGAAGCATCACCACCAGAACCGTCGCGGCCTCAAGACCACCATCAACAACAATGTCATCGAGAGCGAGCACGAGCAGGAGGAGGAGGAGGAGGACCAGGATCACGACGATGTCGATGAGGAGGCGGATGTGGCCATGCTGACATCCACCCCGGATGTGGCCACTTTGCTGGCCGGTGCCAGTGCCTCGGGAGCTGCCTCCCGCTCTGTGTCCCCCTCGTCGGCCGCCTCGCCGGCGCTCCTGCTCAGCTGCCCCGCCTGCGGAGCCGGGGACTTCGAGACCCTGCCATCGCTGTGCGACCACCTGGACGCCCGGCATTCGGACATCCCGGCCAAGTGTCGTGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGTTGCAGGCCCACTGCTGTCGTGGGGGACTAGGACGTCCAGTGGGAGTGGGACTGCCGCCTCTTCTGGGCGCCAGCAGCTCCCCGCTCCACGGCGACGACGATGCCGAGGACGAGGATGATGAGGATGCGGAGAGACGTCTGCGGATGGAGAAGCAACGTTTGGCCGACCAGCGCCGACCAGCCGACCAGGACTTCTTCCAGCAGCTCTACCTCAAGGGCAAGACCTCTGGCGAGCATCCGCCGTCGCCCATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTGCACCAGCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGCCGTGACCAGGAGGAGGAGGCCCAGGATGCCTTCACCTCGGAGTTCCGGCGGATGAAGTTGCGGGGAGAGTTCCCCTGCAAGCTCTGCACCGCCGTATTCCCCAATCTGCGCGCCCTCAAGGGCCACAATCGTGTCCATCTGGGTTCAGTGGGTCCGGCCGGGCCGTTCCGGTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCCGCCCTGGTGCGGCACATGCGCACCCACAACGGAGATCGTCCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTGCGGAACCGGCACGGCAAGACCAGCCGGGAGGAGGTGAAGCGCGCCATCATCTACCATCCGGCGGAGGACGCCGGCTGCGGCGAGGACGGCAAGTCCCGGCTGGGCGAGGATCTGGACCTGAGCTTCCGCTCGATCAGTCCGACTCCGCCGCCACCACCGCCACCGCTCCCGGAGAGCAGCTCCCAGCTGAAGCACATGCTTCTCGGCGAGAATCAGCCAGCGGGTGGATCTGTCGGAGGAGCAGCTGCCCCCCAGCAGCCCCCGCTGAAGATCCAGGTGAAGAGTCTGGACCAGCTGGTGGACAAGAAGCCCAGCCAGGAGAAGAGCTCGCCCAGCGCCGCCCTGGACTTCAGCATGGACGTGCTGGATCTCAGCAAGAAGCCATCGAGCGGATCGGCGGCCATTACCCCGACACCCACACCGAATCCGGCTCCGCTGGTGCCTCCGCCGGGAGTGCCTGGCACCCCGGACTTGGCCGCCGCCCTGGAGCAGCAGCAGTTGCTCCTCGCCCAGCAGCAGCTCTTCGCCGGAGTCGCCGGTGATGCCGCCTCCCAGTATGTCCAGCAACTTTTCCGCAGCCTCATGCTCCAGTCCCAGGGTCCTGGCTTCTCGTACCTCTATGGTGCCTTCATGGCTCCGCCGCCGCCGCAGGCCAATCCGGAGAAGCCCTCACCGCTGGTGAGTCCGCCTACCCGGGGCCTGAACCCTCTGCCAATGGGTGGTGTGGGCGTGCCAGTGCCTCCGGGCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCGAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACCCTCCGCAGCAACATGGAGCGCCACGTGAAGCAGCAGCACCCCCAGTTCTATGCCCAGCGCCAGAGGAGCGGCCACCATGTGATGCGCGGACGTGGCGCCTCCAACGCCGCTGCCGCTGCCGCCGCCGCAGCTGCTGCCGCTGGCATGGGAGTTCCCGGCGTGTCATCCTCTGGCGTCGGCTCCGGAGCTCATCATCATCCCGGCCATGGTCACGGACACGGTCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATTCTGGCCCAGCAACTGAAGGCCCACAAGAACACAGATCTGCTGCAGCAGGCCCTGGCCCACGGATCAAGCAGTGTGTCCGGCAATCCCCTCCTGCACTTCGGCTATCCGCTGGCCACTCCGCCGCCCAACTCTGCACTGCACAACGGCGGCAGCGGACAGACGGGAAACGGAGTGCCCATGGTCTCCATGGACGACGATGAGCCCAAACTGATCATCGACGAGGACGAGAACGACAACGACGTGGAGGAGGTGGACGACTTCGAGGAGGACGACGAGGAGGAGGAGGAGGATGAGCCGGAGGACGAGCCCGAGATCATTGCCGACGAGGAGCCACTGCCACGCGACGAGGAGGAGGACCAGCCGGAGGTCAAGATGGAGGAACTGGAACTGCCGAAGCCACTCACAGAGCAACTGCCTCTCGAGGCGGCCCAGAAGACCGCTGAGACCATCCTGGAGCAGGCCATCAAGGCCGGCAAGCCCATGACCACGCCCCCGCCTCCGGCGAAGGAGCAGCAACTGGAGCAGATCGCTCCGCCCGCTCCCAGCACCCTGAAGACGATGATCGCCCAGGCGGAGTCCGTGGCCAAGTCCCTCAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTAGTGGCCTCCGGCAGCGCCTCCGAGAGCAACAACAGCGGCACCGAGGACGTCACCAGCAGCTCCTCCAGCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAACAGGGTCTCCTGCCCGTACTGCCAGCGCATGTTCCCGTGGAGCAGCTCCCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATTCCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGTCGCCAGGAGGCGGAGCGCGAGCGTGAACGCGAACTGGAGCGTGCCCGGGAGCGGGAGCTGGAGCGGGAGCGCGAACTGGAGCTGGAGCGCGAGCGGGAGCTGGCCGAGAAGGAGAAGGAGCGCGAACGCCAGCAGCTCATCCAGAAGTTGGCTGCCCAGATGGCCGCAGCCGCCGCCGTGGCTGCCACTGTCCCCGGCACCCCGGGAGTCGTCACGCCCGGCGGACTAGATGCTCAAGCTGGCGGAGATCTGCCCTACAAGTGCCACTTGTGCGAGGGCTCCTTCGCCGACCGGCTGCAGTGCCTCGAGCACATCAAGCAGGCCCATGCCCACGAGTTCGCCCTGCTCCTCGCCAAGGGCGCCATCGAGAACGAGCCCGTGCTGGGCGAGTCGGCTTCGGGGAACCCCAACCAGCCCCCACCAGCCAGCCAGCAGCCCCACTCCGACGATGAGGCCACCAACGGCGTGGTCGGTGGAGCCGGAGGCCGTGGCAAGTACCCGGACTACAGCAACCGGAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGCCACATGCGCACCCACTCCGGAGAGCGCCCTTTCCAGTGCGAGACCTGCCTCCGGAAGTTCACCCTCAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGTGGACGTGCCCATAACGGCGATGCCCCCGGCTCTGACTGCTCCGATGATGAGCAGGTGAGCAGCAGCCCACCTGGCACTCCGGCTCCGCCCACATCCACCACCGCCAACAACAACAACAGCTGCCACACCAACAACAACAACAACAACACGGTGAGCGGCAAGTTGGGCCTGAAGCTGCCGAAGCTGCACGAGCTGCTGGACAAGGCGACGGAGTGGCGGGCCAGCCGGCTGGCGGGGGAGCACAAGGAGAACCTGGGCGAGGCGACGGCCCCCTCGGGCTCCAGCACGGATCTGATCGGGAATCTGTTGGGGATCAGCGACCAGGGCATCCTCAACAAGCTGCTCTCCTCGGCCGACGAGGCGGCCAAGCTCCTCGGGGTGGACAACAAATAG
Protein Sequence: MLAAQQQQQQHNTSNNTNTNTTENEMERQRRDSTTSESSLEHLDLGRTPKKLSAVSSGGGVGGSGSLVLQPTSTPHEVATATSRKRKLRQLQHHHQDLLSDEDEEEEEASAPGARPHGRQKQRRNASIVLDGSGSDASSLRKKFRLNRSAAAVAAVSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSGGSSPQGGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANHNHKDMELDLELEEEVKHHHQNRRGLKTTINNNVIESEHEQEEEEEDQDHDDVDEEADVAMLTSTPDVATLLAGASASGAASRSVSPSSAASPALLLSCPACGAGDFETLPSLCDHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGGLGRPVGVGLPPLLGASSSPLHGDDDAEDEDDEDAERRLRMEKQRLADQRRPADQDFFQQLYLKGKTSGEHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGSVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIIYHPAEDAGCGEDGKSRLGEDLDLSFRSISPTPPPPPPPLPESSSQLKHMLLGENQPAGGSVGGAAAPQQPPLKIQVKSLDQLVDKKPSQEKSSPSAALDFSMDVLDLSKKPSSGSAAITPTPTPNPAPLVPPPGVPGTPDLAAALEQQQLLLAQQQLFAGVAGDAASQYVQQLFRSLMLQSQGPGFSYLYGAFMAPPPPQANPEKPSPLVSPPTRGLNPLPMGGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAGMGVPGVSSSGVGSGAHHHPGHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVSGNPLLHFGYPLATPPPNSALHNGGSGQTGNGVPMVSMDDDEPKLIIDEDENDNDVEEVDDFEEDDEEEEEDEPEDEPEIIADEEPLPRDEEEDQPEVKMEELELPKPLTEQLPLEAAQKTAETILEQAIKAGKPMTTPPPPAKEQQLEQIAPPAPSTLKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERARERELERERELELERERELAEKEKERERQQLIQKLAAQMAAAAAVAATVPGTPGVVTPGGLDAQAGGDLPYKCHLCEGSFADRLQCLEHIKQAHAHEFALLLAKGAIENEPVLGESASGNPNQPPPASQQPHSDDEATNGVVGGAGGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCETCLRKFTLKHSMLRHMKKHSGRAHNGDAPGSDCSDDEQVSSSPPGTPAPPTSTTANNNNSCHTNNNNNNTVSGKLGLKLPKLHELLDKATEWRASRLAGEHKENLGEATAPSGSSTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504177;
90% Identity: iTF_00580189;
80% Identity: -