Dame014331.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila americana
Gene Symbol
Hr39
Assembly
GCA_018152915.1
Location
JAECXQ010000582.1:4451201-4455442[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2 1.4e+04 -5.6 6.7 144 144 210 210 18 274 0.55
2 3 2e-10 1.4e-06 27.7 0.0 1 40 410 450 410 478 0.81
3 3 8.2e-84 6e-80 269.4 0.4 182 408 490 707 432 707 0.91

Sequence Information

Coding Sequence
ATGCCCAACATGTCGAGCATAAAGACGGAGCAGAGCGCGTCACCCGGTGCCACCGGCTGCAGCTATCAGCTGCCGGTGAACATGTCCACAACGACAGCGGCGCCCACTGTGCGCCACAATGTGTCCGTGACGAACATCAAGTGCGAGGTGGAGGAGCTGCCCACGCCGAATGGCAACCTGGTGCCGGTTATAGCCAACTACAATAATCATAATCATAATCACAATCACAATCATAGCGGGGGCAACAGCAGCAGCAGCCTGCGCATACCGCTGGGCGGCGGCGGCAAGGACGAGGATGAGTCCGACTCGGAGGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGCCGACGGGCAGCCGACAAGAACGGGCCGCGACCCATGTCCTGGGAGGGTGAACTCAGCGACGCCGAGACGAACGGCGGCGAGGCGCCGGACGAGGAGCTCATGGAAACGGAGACGGTGGTCAAGAGCGAGGCCAGCAGCGGTGCCACAAGCACCACATTGGCCGGCCGCCAATACGAGCCGGCGTCTGCGCTGTGCGATCGCAGCAAGTCGAGCAGCGGCGGCCATCTGCCGCTGTTGCCCGCCAATCCCAGTCCCGACTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACCTCGCGCCATGCCCCCTACACACCATCGCTGAGCCGTAACAACAGCGACGCCTCGCACAGCAGCTGCTATAGCTACAGCTCCGAGTTCAGTCCGACGCACTCGCCCATCCAGGCGCGCCATGCGCCGCCCGCGGGTGCCGCTCTCTTTCCCGGCCATGCCAATGGCGGCGGCGGCGGACTGCATCATCATAGCGTGCTGTATCCGCCGCTGAATGTGGACGCAACCGTTGCCGGACAGGAAGCGCAAAATCTCAGCATGGATGGCAGCAGCAGCAGCGGAGGCGGCGGTGCCCTGGATGCGATTGCCACGCTGCCGGCCTCGCCGGCGGGCATCTCGCGGCAGCAGCTCATCAATTCGCCGTGCCCAATTTGTGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTACAGAATCGCAAGAACTATGTGTGCGTGCGCGGCGGCCCCTGCCAGGTGAGCATCTCGACGCGCAAGAAGTGTCCCGCCTGCCGCTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCCATACGCGAGGATCGCACACGCGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCAATGCTCAGCCCCCTGCTCACCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATACGGAACTGGCGCGCATTAATCAGCCGCTGTCCTCATTTGCATCTGGCGGCAGTTCGTCGAGCGCCGCGGGCGGTTCGAGCACCGCCGGACAGCCAGCTGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCGTCCAATGGCGAGAACGCCAATCCCGATCTGATTGCCCACCTCTGCAACGTGGCGGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAATATCTCGATTGACGATCAGATCTGCCTGCTCATCAATTCGTGGTGTGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCCATTGATACGCCCGGCGAGATCAAGATGTCGCAGGGCCGCAAGATTACCCTGGCGCAGGCCAAAACCAATGGCTTACAGGCCTGCATTGAACGCATGCTGAATCTGACGGATCATTTGCGGCGCCTGCGCGTTGATCGTTACGAATACGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGATACCACGGAGTTGCACGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGCCTGCAGGCCTACACGTTGGCCCATTATCCCGATACGCCGTCCAAATTCGGGGAGCTGCTGCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGCCAAGGAGATGCTGACGATCAAGACGCGCGATGGCGCAGATTTCAATTTGCTGATGGAACTGCTGCGCGGAGAGCATTGA
Protein Sequence
MPNMSSIKTEQSASPGATGCSYQLPVNMSTTTAAPTVRHNVSVTNIKCEVEELPTPNGNLVPVIANYNNHNHNHNHNHSGGNSSSSLRIPLGGGGKDEDESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSDAETNGGEAPDEELMETETVVKSEASSGATSTTLAGRQYEPASALCDRSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGAALFPGHANGGGGGLHHHSVLYPPLNVDATVAGQEAQNLSMDGSSSSGGGGALDAIATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLTLLQEIMDVEHLWQYTDTELARINQPLSSFASGGSSSSAAGGSSTAGQPAGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLAKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00506139;
90% Identity
iTF_00475264;
80% Identity
iTF_00475264;