Damb000454.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ambigua
Gene Symbol
RREB1
Assembly
GCA_018150905.1
Location
JAECWS010000027.1:4120993-4127120[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.029 2 8.8 0.8 1 21 252 272 252 274 0.93
2 11 0.0002 0.014 15.6 0.2 1 23 284 306 284 306 0.98
3 11 1.7 1.1e+02 3.3 3.7 2 19 447 464 447 466 0.97
4 11 0.03 2 8.8 0.1 1 23 618 640 618 640 0.97
5 11 1e-05 0.00068 19.7 0.7 1 23 650 672 650 672 0.99
6 11 0.00067 0.046 14.0 2.0 1 23 678 701 678 701 0.97
7 11 0.0024 0.16 12.2 2.0 1 23 986 1009 986 1009 0.95
8 11 7e-05 0.0047 17.1 0.3 2 23 1403 1424 1402 1424 0.97
9 11 0.12 8 6.9 6.3 1 23 1430 1453 1430 1453 0.97
10 11 0.0097 0.66 10.3 0.6 3 23 1654 1674 1652 1674 0.95
11 11 0.0011 0.073 13.3 4.8 1 23 1680 1702 1680 1702 0.99

Sequence Information

Coding Sequence
ATGTTGGCAGCACAGCAACAGCAGCAGCCCCAGCCTCAGCCACACAGCACTGCCACAGCCAGCGCCACCGCCGCCGCCGCCACCGTAGTCACGCAGGCAGCGATGGAGCGTCAGCGGCGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCATCTCGACCTCGGCCGCACACCAAAGAAGCTGAGCAGCAGCAGCGGCCCACAGCCCACGTCGACGCCGCACGACACGGCCCCAGCAACGGCGGTGATGTCAGCGTCGCGCAAGCGCAAGCTGCGACAGCACCAACAGCACCAGCATCAGCAGCAGGATCTGCACAGCGACGACGAGGAGGAGGAGGAGCCACGTCCGCTGGAGGAGACGATGGCTGCTGTGCAGCGGCCGCGACACAAGCAGCGACGCAATGCCAACGCCTCGGCGGCGGCCAGCGCCAGCATCGTGATGGACTACAGTGCCGGCGACGCCAGTTCGCTGCGCAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAGTCCGGCATCGGGGCCGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACCTGCCGCATCTGCTCCAAGGTGCTCTCTTCGGCATCGTCGCTGGACAGACACGTGCTGGTGCACACGGGCGAGCCGAACAACAACAACAACCACAACAGCCACAAGGAGATGCAGCAACAGCAGCAGCAGATCCAGGAGCGGATCAAGCAGCGTCGCCCCAAGACCACCATCAACAACAACAACATCATCGACGAGGGCTCCCCGCCAGCGGCGGAGGAGGAGCACGAGGAGCAGGACATGAAGGAGGAGCAGCCCGATGCAGACAGCGACGAGGATGTGGCCATGCCGCTGTCCATCACCAGCACCCCGGATGTGGCCACCCTGCTGGCCGGAGTGAATGCATCCTCGCGCGCTGAGTCGCGCTCCCGCTCCCCCTCGCCGGGGATGCCACTGCTGAGCTGCCCCGCCTGTGGCGCCGCCGACTTTGACACGCTGCCCGGCCTGTGCGCCCACCTGGACGCCCGCCACTCGGACATACCCGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGACTGGCGGGGGTGGATCTGCCGCCGATGCTGGGTGCCAGCAGCTCGCCGCTGCACCAGGGCGAGGACGACGAGGATGAGGAGGACGCCGAGGACGGGGACGAGGCCAGGACCGAGCGCGAGGCGGAGCAGCGCGATGAGTTTTTCCAGCAGCTGTACCTCAAGGGCAAGGCAGCCGCTGCCGCAGCAGCTGCCGCCGGGGCATCCATTGGGGCATCGTCGCCGCCGTCCCCCATCAAGCACGAGCCCGCGGACAGCAAGGATCTGGCGGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTGCACCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGATGGGCGCGACCAGGAGGAGGAGGCCCAGGACGTCTTCACCTCCGAGTTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCGTGGCCGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCATCTCGGCTCCGTGGGCCCCTCGGGCCCGTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCCGCCCTCGTGCGCCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGATGCCAGCTGCGAGGACAGCAAGTCCCGGCTGGGGCTCGGCGACGATCTGGCCGATCTGAGCTTCCGCTCCATCTCGCCGCCACCACCGCCGCCGCCGCCAGCCAGTGCCCCGATCGCCGAGGGCGGCTCTCAGCTGAAGCACATGCTCCTGGGCGAGCCATCGCCATCGACATCGCATACTCCCACAGCAGTCGCCGCTGCAGCTGCTGTTGCCGGGCCACCGTCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAGAAGCCTGCCGCAGGCGGCAGCCCGGCGCTCGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACAGCGGGAGGATCTGCATCTGCCTCCGCCTCCGCCTTGGCGGCATCGCCAGCCGCAACGGTGCCAGAACTGTCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAGGCGATGCTGCCTCCCAGTACATGCAGCAGCTGTTCCGCAACCTCATGTTCCAGTCGCAGACGCCGGGCTTTCCCTTCTTCGGGTTCATGCCGCCGCCGCCCCCACAGGGCAATGCCGAGAAGCAGCCGCAGCTGAGTCCACCCACGCGCATGGGCGGCCTGCCGCTGCCGATGCCGGTGGGCGTGCCCGTGCCGCCCGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCGCGCTTCACCCTGCGCTCGAACATGGAGCGGCACGTGAAGCAGCAGCATCCCCAGTTCTACGCCCAGCGCCAGCGCAGCGGACACCATGTGATGCGCGGCCGTGGAGCCTCCAATGCCGCGGCAGCTGTGGCCGCAGCCGCCGCCGCAGCGGCAGCCATGAGCCAGGGCGGATCCGGAGCGGGCCACGTGCACGGCCATGCCCCCATTTCGGAGCAGGTCAAGTACGCCATCCTGGCGCAGCAGCTGAAGGCGCACAAGAACACGGATCTGCTGCAGCAGGCGCTGGCCCACGGCTCCAGCAGCGTGGCCGGCGGCAATCCCCTGCTGCACTTTGGCTACGGCCCCCCGCCCCAGGCGCAGGCCCACGCCCACTCGCACGGCCACGCCCACTCGCACGCGCACGCCCAATCGTCCAGTTCTGGCGCCCATCTGCCGCATCTGGTGAACGGGCTGCACAACGGGAACGGGAATGGAAGCAGTGGGATCGGTGGACAGGCGAGTGCCATCGATGACGACGAGCCCAAGCTGATCATTGACGAGGACGAGGATGGCGAGGGCGATGTGGAGGAGTTTGATGACGATGAGGAGGAGGAGGAGGATGAGCCCGAGGACGAGGAGCCGGAGCCAGAGCCAATGGACGAGTCGGAGCAGCCGGAGGACGAGCAGGAGCTGCCCAAGCCCCTGGAGCAGCCGAGTGCTGCTGCCGCTGCTGCATCGGCCAATGAGGCGGCCAAGAAGATGGCCGATACCATCCTCGAGCAGGTGATCAAGGCGGGCAAGGGCAGGGCCACGCCCACAGGCACCGTTACGCCAATGAGCACGCGCACGCCGTCTCCCTCGCCCAGTCCGTCGGAGGAGCCGATGCCGAGCAACGCGATGCCGGAGCCGAGTCCCCCGAATCCCACCATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCGCTGAAGGAGGTGGCCAGCTCCCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGAAGCGCCAGCGAGAGCAACAACTCCGGCACGGAGGACGTGACCAGCAGCAGCTCCGGCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGGCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTACTCTTCACCACGAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGTCGCCGCCAGGAGGCGGAGCGGGAGCGCGAGCGCGAACGGGAGCTGCAGCTGGAGCGGGAGCGCGAGAAGGAGCTGGAGCGCGAGCGGGAGCTGGAGCGGGAGCGCGAAAAGGAGCGCCTGGTGCTCATCCAGAAGCTGGCGGCGCAGATGAATGCCGCTGCAGCTGCTGCCGCCGCCGCTGCTGCCTCTGCCTCGGCCTCGTCCGATCCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAGGGCTCGTTCGCCGAGCGGCTGCACTGCCTCGAGCACATCAAGCAGTCGCACGCCCACGACTTTGCCCTGCTGCTGGCCAAGGGAGCCATCGAGCCGGAGTCGACCCCGGCCCGTGGTGCCGGCGAGTCCAACCACCAGCAGCAGCAGAGCACCCCGGGCGCCGGCTCCGACGATGAGGCGAGTGGCGGCGGTGGCCGCGGTGCCTCCGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCCTGCGCCGCTTCTGGTCCACCGAGGATCTGCGCCGTCACATGCGCACCCACTCCGGGGAGCGGCCGTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGCGCCCACAACGGCGACAATCCTGGCTCCGACTGCTCCGACGATGAGCAGGTCGCCACACCGCCGTCCACCCCAGGTCCCCAGATGCCTTCGGCACCGGCCACACCCAACACCAACAACAACAACAGCTGCCAGAACAACAACAACAACAGCAGCAACACCAATGCCAATTCGAAGTTGGGTCTGCGTCTGCCGAAGCTGCACGAGCTGCTGGACAAGTCGAGCGAGTGGCGTGCCAGCCGGCTGGGCGAGCACAAGGAGAACATTGGGGAGGCGGCAACACCGTCGGTGGCCGCCTCGGTGGCCAGCTCCGATCTGATCGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTGCTGGGCGTGGACAACAAGTAG
Protein Sequence
MLAAQQQQQPQPQPHSTATASATAAAATVVTQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTAPATAVMSASRKRKLRQHQQHQHQQQDLHSDDEEEEEPRPLEETMAAVQRPRHKQRRNANASAAASASIVMDYSAGDASSLRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGEPNNNNNHNSHKEMQQQQQQIQERIKQRRPKTTINNNNIIDEGSPPAAEEEHEEQDMKEEQPDADSDEDVAMPLSITSTPDVATLLAGVNASSRAESRSRSPSPGMPLLSCPACGAADFDTLPGLCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGLAGVDLPPMLGASSSPLHQGEDDEDEEDAEDGDEARTEREAEQRDEFFQQLYLKGKAAAAAAAAAGASIGASSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSISPPPPPPPPASAPIAEGGSQLKHMLLGEPSPSTSHTPTAVAAAAAVAGPPSKIQVKSLDQLVDKKKPAAGGSPALDFSMDVLDLSKKPTAGGSASASASALAASPAATVPELSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGDAASQYMQQLFRNLMFQSQTPGFPFFGFMPPPPPQGNAEKQPQLSPPTRMGGLPLPMPVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGAGHVHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGGNPLLHFGYGPPPQAQAHAHSHGHAHSHAHAQSSSSGAHLPHLVNGLHNGNGNGSSGIGGQASAIDDDEPKLIIDEDEDGEGDVEEFDDDEEEEEDEPEDEEPEPEPMDESEQPEDEQELPKPLEQPSAAAAAASANEAAKKMADTILEQVIKAGKGRATPTGTVTPMSTRTPSPSPSPSEEPMPSNAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELQLEREREKELERERELEREREKERLVLIQKLAAQMNAAAAAAAAAAASASASSDPGAGGDLPYKCHLCEGSFAERLHCLEHIKQSHAHDFALLLAKGAIEPESTPARGAGESNHQQQQSTPGAGSDDEASGGGGRGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPQMPSAPATPNTNNNNSCQNNNNNSSNTNANSKLGLRLPKLHELLDKSSEWRASRLGEHKENIGEAATPSVAASVASSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00611595;
90% Identity
-
80% Identity
-