Basic Information

Insect: Drosophila algonquin
Gene Symbol: zfh1
Assembly: GCA_035041765.1
Location: JAWNKY010000178.1:152039-156181[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 6e-05 0.005 17.4 1.9 1 23 143 165 143 165 0.97

2 15 0.0031 0.25 12.0 1.7 3 23 173 193 171 193 0.94

3 15 0.00019 0.016 15.8 0.4 1 23 342 364 342 364 0.98

4 15 0.00037 0.03 14.9 0.6 1 23 370 392 370 392 0.98

5 15 0.00064 0.053 14.2 4.2 1 21 422 442 422 444 0.93

6 15 2.1e-05 0.0017 18.8 1.5 1 23 482 504 482 504 0.96

7 15 0.017 1.4 9.7 1.3 1 23 510 533 510 533 0.97

8 15 0.025 2.1 9.1 0.4 3 19 542 558 541 559 0.95

9 15 0.00015 0.012 16.1 5.6 1 23 568 590 568 590 0.97

10 15 0.045 3.7 8.4 0.4 2 23 596 617 595 617 0.96

11 15 8.8e-06 0.00073 20.0 1.0 1 23 626 648 626 648 0.98

12 15 0.001 0.083 13.6 0.1 3 23 656 676 654 676 0.97

13 15 2.4e-05 0.002 18.7 0.5 1 23 682 704 682 705 0.96

14 15 0.0054 0.44 11.3 0.4 1 23 715 737 715 737 0.98

15 15 0.0054 0.45 11.3 0.2 1 23 1267 1289 1267 1289 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	6e-05	0.005	17.4	1.9	1	23	143	165	143	165	0.97
2	15	0.0031	0.25	12.0	1.7	3	23	173	193	171	193	0.94
3	15	0.00019	0.016	15.8	0.4	1	23	342	364	342	364	0.98
4	15	0.00037	0.03	14.9	0.6	1	23	370	392	370	392	0.98
5	15	0.00064	0.053	14.2	4.2	1	21	422	442	422	444	0.93
6	15	2.1e-05	0.0017	18.8	1.5	1	23	482	504	482	504	0.96
7	15	0.017	1.4	9.7	1.3	1	23	510	533	510	533	0.97
8	15	0.025	2.1	9.1	0.4	3	19	542	558	541	559	0.95
9	15	0.00015	0.012	16.1	5.6	1	23	568	590	568	590	0.97
10	15	0.045	3.7	8.4	0.4	2	23	596	617	595	617	0.96
11	15	8.8e-06	0.00073	20.0	1.0	1	23	626	648	626	648	0.98
12	15	0.001	0.083	13.6	0.1	3	23	656	676	654	676	0.97
13	15	2.4e-05	0.002	18.7	0.5	1	23	682	704	682	705	0.96
14	15	0.0054	0.44	11.3	0.4	1	23	715	737	715	737	0.98
15	15	0.0054	0.45	11.3	0.2	1	23	1267	1289	1267	1289	0.97

Sequence Information

Coding Sequence: ATGAACCACCAGGACTATGGCGGCATCCAATGGATACAGCAACACCCCGCCGCATCCGACTGCGGGGTGGATATACTGGACGGTGGGACGCCGGACGGGTATCATCTCGTGACCGATGAGGCGACGGGCGAGGATCTTGACCATATGGCGGCCGAGAATCTCATATTCATGGCCCGCGACGGTCAGCTGAGTGAGATCATAAGTGGCGGCAACGCTGTCATAGTCACTGCCGATGGCCACACCGTGACATACGCCGAGTCCTTTGAGGATGACGCCCAGGTGGTCACGGAGGAGGTCATCACGGACGATTGGGTGCAGCATCAGGGAGCCGAGCGTGTGGAAATCGCCGCGGAGCAAATAGCTGGAAATGGAAGCTCGCAGGAGCTGCTGGACATGGAGCAGGACGAGTACACGGCCCTGCGACCGTATCCCTGCGACTTTTGCAGCCGCCGCTTTAAGAAGAAGACCAGCCTGAACACCCACATGCTGGCCCACCAGAACGATCGTCCTCACCTTTGCAAGCTGTGCGGGTCACGCTTCTCTCGCCGTGCCGAGCTCATCAGTCATTTCAAGGCGCACGCCGAGGCTCAGGATGCAGCGGATGccgaggcagcagcggccacaTCCATTAAGTTCGAGCACCGCCCAATAGAAGATCATTACTACGAGCACGATTGGCCTTTATACCAGCAGGACCAGGGCGACGAGGaggcggagcagcagcagctggtatCCAGTAGCGAAACTCAGGACCTCAACCTGGTGCACCAGGAAAGCTACAATGTTGCCGCAGTTACTGTCGATGCTCCAGTGCCGACCCGTGGAAGGATCAGTCGCCTGAAGCCAAAGGAGGAAGCCACACAGTACATTGTGATTTCCGACAAGAGGGAAGCGCCCCAGATGCAGGACTATTTGCAAAGCGAGCCCATGCAGGCGGCGGTCACCACCTCAACACCGATTGAGCCCCAACCTAGAGCTGATCTTCCCCAGCCGAATTATCCTGTGCTGGACGACAGCAAGCCTTTCGTGTGTCAGCAGTGCGGCTTGGCTTTTGCCAGGGAGAAGGCGCTCTTCTCTCACACGAAGAACCACCGCGTGGACTCGCCCTTCGAGTGCAACCAGTGTCAGGAGATGTTCTGGGATAATAGCAGCTTGCTGGAGCATCAGAAGACGCATCAGTTTGAGGAGAGCAACTCCGAGTACGATCCAGCATCGGGGGACGACAGTGTCAGCGAGTCGGAAACGGAGCAGCTCTATGGCGACTTTTACTGCAGCGAGTGCGGCATTTCCTTTCACAGGCAGGACCTGCTGCGACGTCATGCCAAGTGCCATTTCAAGCAGCCAGACGCAAGTAACGTTGACCAAAAGCCGATtgtgggagagaggggagtCACCGACGAAGTGATGGCTGGAGATGCCGAAAATGCCAAAGAAGATGCTGCCCACCGGTGTCACACGTGCGGCAAGTGTTTTCCCGATGCCGTTGCGTTGAACGCCCATGCCGAAATCCACGCCCGTTTTCCGCCCTTCAAGTGTGTCTTGTGCGGTGTCAGCTTCTATGAAGAGCAGGCCATCAAGCGGCACTTGCACACGCGGCATCCGCACGAGCTGAAGGCCAACtcgtgtgtgctgtgtggaaAGGAGTGCCGGGATCGGAAGGCTCTCATCAAGCATGCCTGGGACCACTCGCGTGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTCCATAACAAGGCGCGTCTGAAGCGGCACATGGCCTCGCATCGGGACAAGTCGGTGGTGTGTGAGGTCTGTCAGGAGGAGTTCCCCGACGGACGCACGCTATCCAATCATCGCCACTCTCATAGCACCACCTCGCCGGGTAAACTTTTCCCGTGTCATGAGTGTGGCAAGACCTTCGGTTCGCGCAGCTCCCAGCAGATTCACGTACGCATTCATACGGGCGAGCGTCCGTACGGCTGTCGCTACTGCTGGAAGGCCTTTGCCGACGGCGGCACTCTGCGCAAACACGAGCGCATCCACACGGGCGAGAAACCCTACGTCTGCTCCGTGTGTCCACGTGCCTTTAACCAGCGAGTGGTGCTCCGCGAGCACATTCGCTCCCATCACTCCGGTATCGATGTAACACTAGGCACTTACCACTGCGGTTTGTGCTCCGAGGACCTGTCCTCGTCCAGTGAGCTCATCCAGCATCTTATCAAGCACAGCGACGCGAACACTGCCAATAAGCGTCAGCCCGTCacGGGACCTCGAAAGTACAAACGACGGCGCAAGCTGCAGCCGCATGAGATTGCCCACATGCGGGCCGAGAACAAGGAAGATGAGCTCTTGCAAGAGGCCGAAGAGTATAACAGTGACTTAGACATCTGCGACTTTGAATTGGAGAACGTGGACCAAATCTTCGAAATGGCAGAATCCCCCAAAAAGGAGAAACGCAAAAAGGGAGCAGCCAAGGAACCGAAGCCGGTTGCCAATGGAACGGCCAAGGCTGTTCCGGATAAGTCGAAAATGCGCTATGATTCCACCAGCAGTCAATCGGATCGCATGTGGGAGGAGAAGTTCCTGCACGACAGCCAGGTGTCGTTGTTTCAAATTGATTCGTTATCGGCTATGAATCAACAACAGTCACCGCTGCCTGCCAGCACCGCCAGTTCCTCTAGCGTTCAAAACACGCGACGCAGTGGCAAACAGCCGCCAGCCCAAGGGCTGGCCAAGACGATGCCACCAGTTCCGGTGAAAGCAAACGCCAGCGCATCATCCTCCTCTACGACTGCGAGctccagcagccgcagccgaaaGAAGGCGGGAACAAGTAAGGCGTCCAATAGCAAGTCGGCTGCTGCGGGAAGCTCGCGTCCGCGAATGATCCACACCGAGAAGACCAAGGCTCCGAAGGCTGCTGACAGCTCGGGCACTGCATCCGGATCTACCAAGAAGACGCGTGCCAAGAGTTACATTACTCGGACAGAGACCAGCAATCTGGATCTGCTTtccagcggcaacggcaagtCGCGAGCCACTGCGTCCAACATTGTCGACGACTATGAGATCATTTCCCCAGCCACGCATCCACCCAACCAGATCAGCTCCAGTCCGTTGCACATTaagcaggagcaagagcagcagcgcGTTCCGATGATGTACGACGACAATCTGCTTATCGATGCAGCGCTGCTGCGGGAGAAGACGTACGAGAGGTTCAATCCCAGCGTGGTCAACGATCTGGAGGAGATTCTGCGCTCTCCACTGAAGAGTGAGCGCAATTCCCGACTGCGTTTCACCAGCGAGTCGTCGACAACACCGCAGTTTCTGCCTGGGGAGGAACAAAACCTCATCAAGATCGAGCCAACTTCTCCCGATCTACGGGAAATGGTTGAGAGTCAGCAGCGTGTCACGGCTACCACTGGCAACACGCCCActtcctcgtcgtcgtcggcccGCACCTCGCGTCACCTGCGCCAGATAACTGCCAACAGTCCGCGTGTGGGCAGCAAACGttccaacaacagcaggcagGACTCTGCCTCCGGCGCGGCAGCCAAGAAGCCCAACacatcctcgtcctcctcttcGTCGGTGTCGGTTGGGAGCAAGACCAGAAGCTCCCAACACTCGTACCTCAGCTACGGTGTGGGCGTGGACTCCTACAATGTGAATGTACCTGCCAGTGCCAACACTGCAGATGTGAGCTCTgcattcttttccatttctgAGGTGGTTTCCGCCGCCGACGCAGCTGATGCTGCAGCCAAGGCTGCCGCGGCCAGTAAGCCTGACCGCAAGAAGCGCAGCTTCGAATGCGAGATGTGCTCGGCCATCTTCTATGATCGCGCGCAGCTGCTGGACcacgtccacatccacatctag
Protein Sequence: MNHQDYGGIQWIQQHPAASDCGVDILDGGTPDGYHLVTDEATGEDLDHMAAENLIFMARDGQLSEIISGGNAVIVTADGHTVTYAESFEDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMEQDEYTALRPYPCDFCSRRFKKKTSLNTHMLAHQNDRPHLCKLCGSRFSRRAELISHFKAHAEAQDAADAEAAAATSIKFEHRPIEDHYYEHDWPLYQQDQGDEEAEQQQLVSSSETQDLNLVHQESYNVAAVTVDAPVPTRGRISRLKPKEEATQYIVISDKREAPQMQDYLQSEPMQAAVTTSTPIEPQPRADLPQPNYPVLDDSKPFVCQQCGLAFAREKALFSHTKNHRVDSPFECNQCQEMFWDNSSLLEHQKTHQFEESNSEYDPASGDDSVSESETEQLYGDFYCSECGISFHRQDLLRRHAKCHFKQPDASNVDQKPIVGERGVTDEVMAGDAENAKEDAAHRCHTCGKCFPDAVALNAHAEIHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYVCSVCPRAFNQRVVLREHIRSHHSGIDVTLGTYHCGLCSEDLSSSSELIQHLIKHSDANTANKRQPVTGPRKYKRRRKLQPHEIAHMRAENKEDELLQEAEEYNSDLDICDFELENVDQIFEMAESPKKEKRKKGAAKEPKPVANGTAKAVPDKSKMRYDSTSSQSDRMWEEKFLHDSQVSLFQIDSLSAMNQQQSPLPASTASSSSVQNTRRSGKQPPAQGLAKTMPPVPVKANASASSSSTTASSSSRSRKKAGTSKASNSKSAAAGSSRPRMIHTEKTKAPKAADSSGTASGSTKKTRAKSYITRTETSNLDLLSSGNGKSRATASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQRVPMMYDDNLLIDAALLREKTYERFNPSVVNDLEEILRSPLKSERNSRLRFTSESSTTPQFLPGEEQNLIKIEPTSPDLREMVESQQRVTATTGNTPTSSSSSARTSRHLRQITANSPRVGSKRSNNSRQDSASGAAAKKPNTSSSSSSSVSVGSKTRSSQHSYLSYGVGVDSYNVNVPASANTADVSSAFFSISEVVSAADAADAAAKAAAASKPDRKKRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480991;
90% Identity: iTF_00601198;
80% Identity: -