Basic Information

Insect: Drosophila aldrichi
Gene Symbol: ush_1
Assembly: GCA_035045965.1
Location: JAWNOM010000007.1:3367101-3387260[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0064 0.47 11.1 0.0 1 20 202 221 202 223 0.90

2 9 0.00028 0.02 15.4 0.8 1 23 279 301 279 301 0.98

3 9 0.049 3.6 8.3 1.0 2 21 346 365 346 366 0.92

4 9 0.048 3.5 8.3 2.9 2 21 747 766 746 767 0.93

5 9 0.0089 0.66 10.6 0.0 3 21 815 833 813 834 0.91

6 9 0.0064 0.47 11.1 0.0 2 23 895 916 894 916 0.98

7 9 0.0037 0.28 11.8 1.3 1 23 922 944 922 944 0.99

8 9 0.0013 0.097 13.2 1.9 1 23 1002 1025 1002 1025 0.96

9 9 0.3 22 5.8 0.7 2 20 1132 1150 1131 1152 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0064	0.47	11.1	0.0	1	20	202	221	202	223	0.90
2	9	0.00028	0.02	15.4	0.8	1	23	279	301	279	301	0.98
3	9	0.049	3.6	8.3	1.0	2	21	346	365	346	366	0.92
4	9	0.048	3.5	8.3	2.9	2	21	747	766	746	767	0.93
5	9	0.0089	0.66	10.6	0.0	3	21	815	833	813	834	0.91
6	9	0.0064	0.47	11.1	0.0	2	23	895	916	894	916	0.98
7	9	0.0037	0.28	11.8	1.3	1	23	922	944	922	944	0.99
8	9	0.0013	0.097	13.2	1.9	1	23	1002	1025	1002	1025	0.96
9	9	0.3	22	5.8	0.7	2	20	1132	1150	1131	1152	0.91

Sequence Information

Coding Sequence: ATGATCAGCAGCCATTCAACGGCAACAAAAGGTGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGATTTGGGCGCACACGAGTTGAGCGAggagaaacagcagcaacagctggagGAGCTGCCCGAGGACgagcaactggagcagcaggCTAGCAACGCCTCTGAGCAGCTGGAGGAGACCGACATGGATCAGGAAATGATCGAGGAGGAGCAGGCAGCGGCACAGGAGGCCAGTGCGCAACAGCAGGAGGTGGCGGATAGCTCGACGACGCCGCCGCGTAGTCCCACGCCTCCTGAGCTGGTGCCGAAGCTGGAGCGCGCCGATTCGCCGGCAACGCCGCCTTCTGTGGCCGCCACGCCCAGTCCGCCGCCAACGCCCACGCCGCCGCTGGTGCTGCCCAAACTGCGTCTCAATGCGCTGCTCGCTTCCGATCCGGCTCTGAAACCTGATGCCAAGGAGCTCAATCTCGAGCCACGCTTGCTCGCTCCGCCGCCACAGCTGGCCAAgcccgagcagcagcagccgcagcagagtTTGCCCGATCCCAGCAGTCTGGTGGAGCCGCTGCTCAAGCCGGCGCGCTTCATGTGCCTGCCCTGCGGCATAGCTTTCAGCTCGCCCTCGACGCTAGAGGCGCACCAGGCGTACTACTGCTCGCATCGCAACAAGGATGCCGACGAGGAGTCGGCCGCCGTGGACAAGGCCACAGGCGCAGCTGGCGCCGGCAGCGCCAATCCGaatgccaacagcagctccaGTGGCGGCAGTTCCGGCTCGGAGCCACCCGCCAAGGTGGCGCGCACGGGCAAGCAGTACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTGAACCGACACATGCGCATGCATCAGACCTCGCCCGCCGCCCCCACCCTGAACAGCCTCTCCGGGCTGGCGGCCAACGGTGTGGtggctgccgccgccgccgcagctgctgcggccggTGCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGGCGCAGCGACGGCCAGCTGACGCCCAAGCCGGAGGCgaacgccagcagcaacaccgGAGGCTCTGCAGCAGGAGTTGGCTCGGCCGCAGGAGCTAAGCACAGTGGGGCCCACAGTCCGCAGACGCGCAATAAGACGCCGACTCCTGCCATGgtcgctgctgcggcggctgcggcggccgctgctgcagctgccgcctcACTGCAGGTGGCGCCGCCGCAACCCTTCCTGGCACTGCCCACCAATCCCATCATCATTGTGCCCTGCTCGCTAATACGCGCCGCCAGCCTCATACCCGGACCACTCACCACCTCCACGTCGGGCATTGTCAATCCGGAGTCCACATGCTTCACCCTGGACAATGGCGCCCTCAAGCCGCTGGCCACGGCGCTCAACATCAACGCGCTAGCGggcaatgccacgcccacgcccacaggcACGCCCATGCCTGGTGGCAATCAGCTGAGCATGCCCGCCCCGGAACCAGAGCGTCCCAGCGCCAGCAACGTCCCGGAGACGGAGTCCAAGACCAGTCCGCCGGAGCCCAAACGCAAGGAGGCCAGTGGCATGCGCGAAACCACGCCCCTCGACCTATCCCTACGTCGCTCGCCCATTTcaccgctgctgcagcgccagcgcctGATGGAGGAAGCGCTGCTCAGCGCCGGCAAGGAAAACCTGGAGAGCAGCGGCCGAACCGGTGGCAGCGTCACCCCGGAGCAGATTGTGTGCGCGCCTTCGCTGCCCAGCAGCCCCTCGATGAGTCCGTCGCCCAAGCGACGTGCGATCAGCCCGCGCAGCTCCGGTGCGGGCAGCGCTGCCTCGATGTCGCCGCCAGCGTTGGCCGTGCCCCATCTGCTGGACAATCTGCAGCCATTGCGCTCCATGTTGCCCGGCGACTTTGCGCTATCCGAATCGCTGCTGGCGAAGACCAATCCGGAGCTGGCGCTCAAgctggctgctgccgctgcagcagctgtggcgggcagcagcagcagcgccgagCTGGCCAGCAAGCTGGGCTTTAGTCCAGTCCAGTCCGGCGCTGCCCCTCCCCCGGCTGTGGCCACTGTTCCGACCAATGCGCCCAACAGCCAGCCACAGATCTATGTGAAGCAGGGTGTGTCCAAGTGCAAGGAGTGCAACATAGTCTTCTGCAAGTACGAGAACTACTTGGCGCACAAGCAGCACTACTGCTCCGCCCGCAACCAGGACACAGGCGTGGATGGTGACTCCAAGAACGCAGTGACACCGCCCGCCGCAGCTGGCCCCGGCGTGACTTCTGGCGCCTCTTCCTTGGAGACGACGCCCGTGGCCTATCAGCAGCTGATCTGCGCCGCCTGCGGCATCAAATACACCTCGCTGGACAATCTGCGCGCGCACCAGAACTACTATTGTCCCAAGGGCGGAGCGGCAGCCACGCCCGCGGAGGCAGCCACGccacagctgccgctgcccaaGGAGAAGTGCGTCAAGTGTAAGACGCTGCACGATCACGGCCAGCCGTGCCCGACGcccccagccacgccccagcTGGCGCCGGCCAGTGTGGCTGCGGCGAACAGCGTGAACAAGTGCCCGGTGTGCGGCGTGGTCAGCCCCACCGCTGCTCTGGCCCGCAAGCACATGGAAATGCACGGCACGGTCAAGGCATTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGTTGCGCGGCATGAGGACCCACATACGCACCCACTTCGATAAGAAGACCAGCGATGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGgatgcggcggcagcagctgcagcagccgcaccgCCACCCCCAGCCTTGGGTCTGGACCTGCCCGCTGTGACAGCGGCCCAGGAGCAGCTGGAACAGCATGCGGCACAGATCTTCAATTGCGATCACTGCAACTATGCCTCCACCTATAAGGGCAATGTGCTGCGCCACATGAAACTGTTGCATCCACACGTGGCAATCAGCTCGCCCTCCATCTCGCCCGAATCCCGTGAGCAGGACGCCAATGCCCATGCCCTGCCCGAGGTGGCGCTGGTGAATGGCGAACGCGAGGCAGCCAGCTTCCACATCAAGTCGGAGCCCTTGGAGCCAGCTGTGGCCACGCTGAGTCTGGTGCACGATAACAACAATTCGCCCATTGGCACGCCGCACACGCACATCAAAGCCGAGCCACTGGACATGGGCATAGAGCTCACCCCAGCCACACTACCGCCCCCCATCGCCAATTCGCCGCTGGGGCCGAGCGCTGCGGAGGCCATGAAGAAATACTGCTCCACCTGCGACATATCGTTCAACTATGTGAAGACCTTTTTGGCGCACAAACAGTTCTACTGCAAGAGCAAGCTGCACCGACCGGAGGCCACTGATAGCCCCAGTCCCACGGTGGGCGTCGGTGGCGCCGCCATGCCGCTGCAGTCGCCCAgcgagctgctgttgctgcagaaGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MISSHSTATKGDCSDTTEEMTVDSRDSKDLGAHELSEEKQQQQLEELPEDEQLEQQASNASEQLEETDMDQEMIEEEQAAAQEASAQQQEVADSSTTPPRSPTPPELVPKLERADSPATPPSVAATPSPPPTPTPPLVLPKLRLNALLASDPALKPDAKELNLEPRLLAPPPQLAKPEQQQPQQSLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEESAAVDKATGAAGAGSANPNANSSSSGGSSGSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVVAAAAAAAAAAGALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEANASSNTGGSAAGVGSAAGAKHSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNATPTPTGTPMPGGNQLSMPAPEPERPSASNVPETESKTSPPEPKRKEASGMRETTPLDLSLRRSPISPLLQRQRLMEEALLSAGKENLESSGRTGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSAASMSPPALAVPHLLDNLQPLRSMLPGDFALSESLLAKTNPELALKLAAAAAAAVAGSSSSAELASKLGFSPVQSGAAPPPAVATVPTNAPNSQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDTGVDGDSKNAVTPPAAAGPGVTSGASSLETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHDHGQPCPTPPATPQLAPASVAAANSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAAAAAAAPPPPALGLDLPAVTAAQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDANAHALPEVALVNGEREAASFHIKSEPLEPAVATLSLVHDNNNSPIGTPHTHIKAEPLDMGIELTPATLPPPIANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEATDSPSPTVGVGGAAMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -