Basic Information

Insect: Drosophila albomicans
Gene Symbol: Klhl18
Assembly: GCA_009650485.1
Location: NC:798589-805113[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.6e-33 5.7e-31 106.5 0.2 1 108 53 158 53 159 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.6e-33	5.7e-31	106.5	0.2	1	108	53	158	53	159	0.97

Sequence Information

Coding Sequence: atgCTACACACCATTTTGTTtagaaaaattgtttttggtcgtttgctgctggcattgtGCCCTGCGACCATAAACATGGATTTGAGCGATAACCAACTGGAGGATCAATCCTTTGTATACAAACACGAACAGCTATTTAGTGAAAGTTTTCCATTGTTCAAGGAGATACGGAGACTGGGTAAACTTTGTGATGTCACCCTGAAGGTTGAAGATCAAACATTCTCAGCGCATCGAGTTGTTCTTGCTGCCACTGTACCATATTTTTATGCGATGTTTACGAATAATATGGCAGAGAGCCGCATCAAGGAAATTACCATGAAGGAGATTGAACCTAGTGCATTAGAGAGTCTTATCAATTATGTTTATAGTGGACAAGTGCGCATCGATAACCAGAATGTCCAAAGCCTTATGGTAGGCGCCTCTTTTCTGCAGCTGTCCAATGTGCGAGATGCATGCGCCACTTTCTTGATATCCCGATTCCATCCACATAATGTTCTGGGCATTCGAACATTTGCCGATTCCATGATCTGCCGCCAGTTGATCGATGCTGCCGATAAATATATCGATCAGAACTTTGCCAAAGTGTCACAGTCCGAGGAGTTCCTTTCCCTAGACTGTGAGCAGCTGTTGGAGCTGATGCGCCGCGATGAGCTTAACGTGCGCAACGAGGAAGTTATCTTTGAGGCGTGCATGCGTTGGGTTAAATATGCCGAGGAGAAACGCTCTGAACTATTTCCACAAGTGTTGGCCGCAGTTCGTCTGCCGCTATTGTCTCCGCAGTTCCTAGCAGATCGTGTTGCTCGAGAGGAGCTAATACGCTCGTCGCATCAATGCAGAGATCTCCTCGATGAAGCCAAGGACTTTCATCTAATGCCTGAGCGTCGTGGCTTATTGCAGAGCTTTCGCACGCGTCAACGTTGTGGTGAATTCTTTACAGGTCAAATTTATGCCGTTGGTGGTCTTGCAAGTACCGGGGAGTCTGTTAGCACTGTAGAGATCTATGATCCCATCACcaagaaatggaaaatgggcGAACAAATGTCCATGATGCGTTCGCGAGTCGGTGTTGCAGTTTTAGATGGCAAACTGTATGCCTTTGGAGGCTTTAATGGCACTGAACGTCTGTCCACAGTCGAAGTGTACGATCCACGTAAGAACAAATGGTCTCAGGGATGTGCTATGCTGTGCAAACGCAGTGCCGTTGGGGTCGCTGCTTTAGATGATTGCATTTATGTTTGCGGTGGCTACGACGGCGTTACATCGCTTAATACTGTTGAGGTTTACTATCCCAAAGCAAATACATGGAAAACGGTTGCTCAAATGATGAAGTATCGATCAGCGGGCGGAGTTACACAGCTTAATGGTTACGTTTATGCCTTAGGTGGGCACGATGGATTGTCCATATTTGACTCTGTAGAGCGATACGATCAAAATGAAGACGTCTGGATAAAGATGTCACCGATGCTTAATCGACGCTGTCGTTTGGGCGTAGCTACGCTGAATGGCAAGATCTATGTGTGCGGCGGTTACTGCGGCAATTCATTTTTGCGTTCTGTGGAATGCTACGATCCGCTGACAGACGTTTGGAAGCTTGTTACGCCGATGAACTGCAAGAGATCACGAGTTGCTTTAGCTGCCAACATGGGAAAATTGTGGGCCATTGGCGGGTACGATGGTGAATCGAATCTGTCAACTGTTGAAGTGTACGATCCCGAGACAGACAAATGGACTTTTATGCCTCCAATGTGTGCACACAGTGGAGGCGTCGGAGCCGGCGTTATACGTATTGATTGA
Protein Sequence: MLHTILFRKIVFGRLLLALCPATINMDLSDNQLEDQSFVYKHEQLFSESFPLFKEIRRLGKLCDVTLKVEDQTFSAHRVVLAATVPYFYAMFTNNMAESRIKEITMKEIEPSALESLINYVYSGQVRIDNQNVQSLMVGASFLQLSNVRDACATFLISRFHPHNVLGIRTFADSMICRQLIDAADKYIDQNFAKVSQSEEFLSLDCEQLLELMRRDELNVRNEEVIFEACMRWVKYAEEKRSELFPQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRCGEFFTGQIYAVGGLASTGESVSTVEIYDPITKKWKMGEQMSMMRSRVGVAVLDGKLYAFGGFNGTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYYPKANTWKTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQNEDVWIKMSPMLNRRCRLGVATLNGKIYVCGGYCGNSFLRSVECYDPLTDVWKLVTPMNCKRSRVALAANMGKLWAIGGYDGESNLSTVEVYDPETDKWTFMPPMCAHSGGVGAGVIRID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00190029;
90% Identity: iTF_00359521; iTF_00548865; iTF_00551649; iTF_00575649; iTF_01321249; iTF_00498210; iTF_00518498; iTF_00562530; iTF_01552514; iTF_00495171; iTF_00563235; iTF_00589603; iTF_00599651; iTF_01321987; iTF_01356195; iTF_00335972; iTF_00478788; iTF_00525188; iTF_00528868; iTF_00542500; iTF_00566852; iTF_00473125; iTF_00478789; iTF_00523013; iTF_00531013; iTF_00573381; iTF_00616965; iTF_01326470; iTF_00338407; iTF_00521415; iTF_00601863; iTF_00501864; iTF_00509160; iTF_00511336; iTF_00516328; iTF_00533864; iTF_00553096; iTF_00804456; iTF_00832232; iTF_00558729; iTF_00564713; iTF_00586025; iTF_00588905; iTF_00593161; iTF_00595305; iTF_00614249; iTF_01554025; iTF_00497450; iTF_00587466; iTF_01324970; iTF_00508395; iTF_00549611; iTF_00556587; iTF_00579339; iTF_00598219; iTF_00519980; iTF_00554444; iTF_00561100; iTF_01559820; iTF_00535373; iTF_00544557; iTF_00569037; iTF_00583021; iTF_01320525; iTF_00336814; iTF_00582318; iTF_00585262; iTF_00803662; iTF_01553294; iTF_01554766; iTF_00476687; iTF_00528111; iTF_00540431; iTF_00557263; iTF_00597423; iTF_01319823; iTF_01327951; iTF_01551791; iTF_00500368; iTF_00510608; iTF_00512784; iTF_00552368; iTF_00567600; iTF_00534641; iTF_00538289; iTF_00493714; iTF_00513522; iTF_00526642; iTF_00586738; iTF_00495923; iTF_00506931; iTF_00607123; iTF_01548915; iTF_00479540; iTF_01551060; iTF_00470933; iTF_00496661; iTF_00509877; iTF_00520693; iTF_00532437; iTF_00530326; iTF_00572662; iTF_01557622; iTF_01558358; iTF_00482295; iTF_00498935; iTF_01323447; iTF_00490840; iTF_00517048; iTF_00519224; iTF_00522232; iTF_00570456; iTF_00576408; iTF_00608504; iTF_00609944; iTF_01322712; iTF_01324184; iTF_01556184; iTF_00339225; iTF_00499641; iTF_00557977; iTF_00560345; iTF_00610713; iTF_00619897; iTF_01327225; iTF_00493018; iTF_00502586; iTF_00545306; iTF_00568314; iTF_00547419; iTF_00901563; iTF_01559099; iTF_00337597; iTF_00514237; iTF_00546717; iTF_00577117; iTF_00506174; iTF_00541822; iTF_00559550; iTF_00583742; iTF_00802910; iTF_00485919; iTF_00543807; iTF_00574111; iTF_01549631; iTF_00475296; iTF_00616256; iTF_00805248; iTF_01325728; iTF_01550336; iTF_00580803; iTF_00478081; iTF_00490145; iTF_00600385; iTF_00474563; iTF_00487363; iTF_00561827; iTF_00565443; iTF_00574883; iTF_00581603; iTF_00613571; iTF_00486628; iTF_00536836; iTF_00548132; iTF_00602660; iTF_00471685; iTF_00512070; iTF_00605639; iTF_00917287; iTF_00483048; iTF_00503336; iTF_00527368; iTF_00533160; iTF_00592456; iTF_00515657; iTF_00514954; iTF_00604170; iTF_00480235; iTF_00536107; iTF_00555915; iTF_00607851; iTF_00619211; iTF_00531724; iTF_00492301; iTF_00593902; iTF_00918222; iTF_00919886; iTF_00517775; iTF_00612879; iTF_00578608; iTF_00483761; iTF_00603409; iTF_00609233; iTF_00612145; iTF_00618482; iTF_00494451; iTF_00504755; iTF_00588211; iTF_00916307; iTF_00541140; iTF_00617716; iTF_00569749; iTF_00594613; iTF_00606389; iTF_00914581; iTF_00473846; iTF_00525942; iTF_00484503; iTF_00523767; iTF_00555159; iTF_00915415; iTF_00611416; iTF_00485209; iTF_00488729; iTF_00501113; iTF_00491578; iTF_00507674; iTF_00919130; iTF_00529627; iTF_00571963; iTF_00577851; iTF_00505468; iTF_00524476; iTF_00543164; iTF_00571228; iTF_00591036; iTF_00480925; iTF_00489438; iTF_00591774; iTF_00590303; iTF_00601119; iTF_00481604; iTF_00537572; iTF_00550313; iTF_00477398; iTF_00475995; iTF_00563977; iTF_00580042; iTF_00566156; iTF_00546031; iTF_00488082; iTF_00539029; iTF_00504056; iTF_00615630; iTF_00614970; iTF_00595995; iTF_00598940; iTF_00584479;
80% Identity: iTF_00556587;