Basic Information

Insect: Drosophila albomicans
Gene Symbol: ftz-f1
Assembly: GCA_009650485.1
Location: NC:26692217-26750736[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 3 1.3e+04 -9.8 18.9 44 176 34 192 10 198 0.40

2 4 3 1.3e+04 -10.7 16.3 76 160 165 282 106 350 0.38

3 4 3.4e-19 1.5e-15 57.1 0.6 1 79 529 606 529 626 0.75

4 4 9e-73 4e-69 233.6 1.0 157 408 745 989 718 991 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	3	1.3e+04	-9.8	18.9	44	176	34	192	10	198	0.40
2	4	3	1.3e+04	-10.7	16.3	76	160	165	282	106	350	0.38
3	4	3.4e-19	1.5e-15	57.1	0.6	1	79	529	606	529	626	0.75
4	4	9e-73	4e-69	233.6	1.0	157	408	745	989	718	991	0.91

Sequence Information

Coding Sequence: ATGGATACCTTTAATGTACCTTTGCTGGCggagaacagcagcagcaacattgtgAGCTATGCAACCAGCAACAATGACACCAGCAACCATCACCAgcaccaccagcaacagcaaacacagcaCCTGCAACATcatcaccaacaacaacaacaacagcagcagcagcaacagttgttgcCGCATCATCACAAGGATCAAATGCTTGCCGCTGGCAGCACACCAATGATACCGTTCATCAACTACACACAACTGCAGAAGGATGTGGTGCAACAGAATTCAAACTCGAATCCTCCGCCAGTCGATAGCTTTAGCACATTGCAGGCCATCGATGCCAGTCAATTGGATGGCGGCGTCTCGTTGAGTGGCCTCTGTGATCGGATCTTTGCCAGTCCCAATCcgcacagcaaccacagcaatcccaacagcagcaaccacaataataacaacaatcacagcaacaacaacaacaacaacaatagcaatagcaataataacaatgtgGAGAAGACagcagcgccatctagcggTGCAGTTATAATTGAATCAGTCACAATGCCATCATTTGCCAATTTGTTgttcaacaacaaccgcaacggcaacagcagcagcaaccacaacaacaacaacaacggcaacagcaacaatcagACTGTGGAATATCATCAACTGAAACCACTTGAAAATGGTGCAAGTTCTGCAGTTAGCACTTCTAGTTTTCTCAGCTCATCGACAGCACAGTTGCTGGACTTTGAGGTGGTTGGCAGCAAGGATGCAAATGCggttgccacagccacagtcacagttgGTAATGGCCTCGccgatacaacaacaacagcagcaacaccatctactgctgctgctgctgttgcaataacaaccacaacgagCACTGCCAATCGACGATCGTTGCATAGTATTGAGGAGCTTGCTGCCAGCTCATGTGCcacatcacaacaacaacaacaacatcaggcTGGCAATCTAAGCGGTTCCAATCTCAGTTCAGAGGATGAGTCCAATTCGGAGGATGAATTTGGTCTAGAGATTGATGATCAAGGGGGCTACCAGGAGACTAACTCCTCGCACTCGCAGCAGAGTGGCAACGGCAATGGCGGTGGCAATGCCACAGCCGGTGGCAACTCGTCGCAGCTGCTGAATGGCGGCAGCACTGGCGGCAACGGTTATATGTTGCTGCCACCAGCTGGTGGCACCTCAGCCACATCGGGTCACATGTCTGGCGGCAATGTTGGCGGTGGCTCTGGCGGTGGCGCCACTGGCACCTCGgctggcggcggtggcaacCATCATGGTGGCACTAGCGCCAGCTCGGGCGGCGGGGGGGAGGCCATCGATTTCAAGCATCTGTTCGAGGAGCTGTGTCCCGTGTGCGGCGACAAGGTGAGCGGCTATCATTACGGCCTCCTCACCTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAAAAGGTTTACACTTGCGTCGCGGAGCGATCCTGCCACATCGATAAGACGCAGCGCAAACGCTGTCCATACTGCCGATTCCAAAAGTGCCTCGAAGTGGGCATGAAGCTGGAGGCTGTTCGAGCGGATCGCATGCGTGGGGGTCGAAACAAGTTTGGGCCGATGTACAAGCGGGATCGGGCGCGGAAGCTGCAGGTGATGAGACAGCGTCAGTTGGCGCTTCAAGCACTGCGCAGTTCAATTGGGTCGGACATCAAGCCGACGCCGCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcaagaaatacaaatacctCAGgtatcCTCACTCACACAGTCGCCGGACTCATCGCCCAGtcccattgccattgccttgGGGCAGGTGAATGCGAGCGGGGGCGGCGGTGTGATAGCCACGCCCATGAATGCCGGCAATGTGAGTGGCGGCGGCAATGGCAGCTCCTCCTTGggcggtggcaacaacaacagcaacaacaacaacaatggcaacaacaacagcagcagcagcacaggcagcaacagcagcctcGGCGGCGGAGGTGGCAACAACGCTGGCggtggcagcggcggcggcggcggtggtggcaacaacaacagcaccgaTGGCCTGCAACGCAACGGAAACggcggcaatggcaacagcaacagcagctgccacgAAACCGGCAATGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTCGATTCTGGCACACATCCATCAAGCACAGCCGACGCGCTCATTGAGCCACTGAGGGTATCGCCAATGATACGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAACTGTTTGCGCTGCTGCAGAAGCAGACGTACAATCAAGTAACCGTGGATCTCTTTGAGTTGATGTGCAAAGTGCTCGATCAGAATCTGTTCTCGCAAGTTGATTGGGCAagaaacaccgtcttctttaAGGATCTGAAgGTGGACGATCAGATGAAGCTGCTGCAACACTCATGGTCCGATATGCTTGTGCTGGACCATCTGCATCATCGCATACACAACGGTTTGCCCGATGAGACGCAACTGAACAATGGTCAGGTGTTCGATTTGATGAGTCTCGGCCTGTTGGGTGTGCCCCAGTTGGGTGATTATTTCAACGAGATACAGAATAAGCTGCAGGACCTTAAGTTCGATATGGGCGATTATGTGTGCATGAAATTCCTAATACTGTTAAATCCAGATGTACGCGGCATTGTCAACAAGAAGACCGTTACGGAGGGGCACGAGAGTGTGCAGGCAGCGCTGCTGGATTACACGCTTACGTGTTATCCCTCAGTCAATGACAAATTCAGGAGGCTATTGAACATACTACCAGAGATCCACGCCATGGCCTCACGTGGCGAGGAGTATCTGTACACCAAGCACTGTGCGGGCAGTGCGCCAACGCAGACGCTGCTCATGGAGATGCTGCACGCCAAGCGGAAGGTGTAA
Protein Sequence: MDTFNVPLLAENSSSNIVSYATSNNDTSNHHQHHQQQQTQHLQHHHQQQQQQQQQQQLLPHHHKDQMLAAGSTPMIPFINYTQLQKDVVQQNSNSNPPPVDSFSTLQAIDASQLDGGVSLSGLCDRIFASPNPHSNHSNPNSSNHNNNNNHSNNNNNNNSNSNNNNVEKTAAPSSGAVIIESVTMPSFANLLFNNNRNGNSSSNHNNNNNGNSNNQTVEYHQLKPLENGASSAVSTSSFLSSSTAQLLDFEVVGSKDANAVATATVTVGNGLADTTTTAATPSTAAAAVAITTTTSTANRRSLHSIEELAASSCATSQQQQQHQAGNLSGSNLSSEDESNSEDEFGLEIDDQGGYQETNSSHSQQSGNGNGGGNATAGGNSSQLLNGGSTGGNGYMLLPPAGGTSATSGHMSGGNVGGGSGGGATGTSAGGGGNHHGGTSASSGGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGGVIATPMNAGNVSGGGNGSSSLGGGNNNSNNNNNGNNNSSSSTGSNSSLGGGGGNNAGGGSGGGGGGGNNNSTDGLQRNGNGGNGNSNSSCHETGNGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVTVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFDLMSLGLLGVPQLGDYFNEIQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVTEGHESVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMASRGEEYLYTKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00472411;
90% Identity: iTF_00472411;
80% Identity: iTF_00472411;