Daff013198.1
Basic Information
- Insect
- Drosophila affinis
- Gene Symbol
- Trl
- Assembly
- GCA_037356375.1
- Location
- CM074802.1:48916536-48922023[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 5.8e-43 6.6e-39 132.1 5.9 1 54 322 375 322 375 0.99
Sequence Information
- Coding Sequence
- ATGTCGTTGCCAATGAATTCGCTGTACTCGCTCACCTGGGGCGATTACGGCACGAGCCTGGTATCGGCCATACAATTGTTGCGCTGCCATGGCGACCTTGTCGATTGCACTCTGGCCGCCGGGGGACGCAGTTTTCCGGCCCACAAAATAGTACTCTGTGCCGCCTCGCCGTTCCTCCTGGATTTGCTAAAGaaCACACCATGCAAACACCCTGTGGTAATGCTGGCCGGCGTCAATGCCAACGACTTGGAGGCACTGCTTGAGTTCGTCTACCGTGGCGAAGTGAGCGTCGACCATGCCCAGCTGCCCTCTCTTCTGCAGGCTGCCCAGTGCCTGAATATCCAAGGACTGGCGCCTCAAACCGTCACCAAAGACGACTACACCACGCACTCGATCCAGCTACAGCACATGATACCCCAGCACCACGACCAGGACCAGTTGATAGCGACCATTGCCACGGCTCCCCAGCAGACGGTGCATGCCCAGGTTGTCGAGGATATTCACCACCAGGGACAGATTCTGCAGGCGACCACCCAAACCAACGCAGCGGGACAACAGCAAACGATTGTGACCACGGATGCGGCAAAGCACGACCAGGCGGTAATTCAGGCCTTCCTACCGGCACGTAAACGGAAACCCAGGGTTAAGAAAATGTCACCTACGGCTCCGAAAATCAGCAAAGTTGAAGGAATGGATACGATTATGGGCACACCGACCTCATCCCACGGCGGCGGTGGAGTGGTACAACAGCAGCAAGTTCTCGGAGAGAACGGATCCGAGGGCCAGATGATCACGTCCACGCCGATCATCAAAAGCGAAGGACAAAAGGTGGAGACGATTGTGACCATGGATCCGAACAACATGATACCGGTAACGTCGGCCAATGCAGCCACAGGCGAAATCACGACGGCAACAGGCACCACGGGCACGTCCGGAGGTAATACAAGCGGCACGACATCCACGCCAAAGACCAAGCGCACCAAACACCCGCCCGGGACAGAAAAacctcgctctcgctctcaatcGGAACAACCTGCTACGTGCCCCATTTGCTATGCCGTCATACGTCAGTCGCGGAACCTGCGGCGTCATCTAGAGCTGCGGCACTTCGCCAAGCCCGGTgtgaagaaggagaagaaaaCATCCAGTGGCAAAAAGTCGGGCAGCGGCACCTCCGGCTCGGGTTCGGGATCGGGCCCTGGTTCGGGTGCGGGTGCAGCGCTGAGCTCGAGTGGAGGAGGAGTGCCCCAGGTACAGACGGTGCAGTCCCTGCACACGCTGCAAGGTGTGCAGGTGAAGAAAGATCCCGatgcccagcaacagcagcagcagcagcaacaacaacagcagcaacagcagcagcagcagcaacaacagcagcagcaacaggcaaTGACAGTGACCACCACCTCGTCGGGAGGAcaagtgcaacagcagcaacagcagcagcaggttcaGGTGCAACAACAGTTGCAGCATCATCAGATCATAGACTCGTCCGGCAATATAACAACAGCCACGACGAGTGCCCAGGCGGCGGCAGTGCAGCAACAGGCGGGCGGTCAACAGCAGCTGGTGGCCCAGGCGGCGGATGGCAGCGAGAGTGGGGCGCCGATGTCGATTGCCCAGGTGCAGACACTGCAGGGGCATCAGATCATAGGCAATTTGAATCAGGTGAATATGACTGATttccaacaacagcagcaacagcagcagccaccacaacagcaaacacaaccCCAACAGACGCTCTGA
- Protein Sequence
- MSLPMNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKNTPCKHPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTNAAGQQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTSSHGGGGVVQQQQVLGENGSEGQMITSTPIIKSEGQKVETIVTMDPNNMIPVTSANAATGEITTATGTTGTSGGNTSGTTSTPKTKRTKHPPGTEKPRSRSQSEQPATCPICYAVIRQSRNLRRHLELRHFAKPGVKKEKKTSSGKKSGSGTSGSGSGSGPGSGAGAALSSSGGGVPQVQTVQSLHTLQGVQVKKDPDAQQQQQQQQQQQQQQQQQQQQQQQQQAMTVTTTSSGGQVQQQQQQQQVQVQQQLQHHQIIDSSGNITTATTSAQAAAVQQQAGGQQQLVAQAADGSESGAPMSIAQVQTLQGHQIIGNLNQVNMTDFQQQQQQQQPPQQQTQPQQTL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00474878;
- 90% Identity
- iTF_00471701; iTF_00536114; iTF_00536424; iTF_00487380; iTF_00487666; iTF_00474172; iTF_00473864; iTF_00474878; iTF_00474580; iTF_00517792; iTF_00518102;
- 80% Identity
- iTF_00471701;