Daff000910.1
Basic Information
- Insect
- Drosophila affinis
- Gene Symbol
- -
- Assembly
- GCA_037356375.1
- Location
- CM074799.1:7391280-7397876[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00074 0.062 14.1 1.5 1 23 143 165 143 165 0.97 2 13 4.3 3.6e+02 2.3 0.8 1 23 171 194 171 194 0.89 3 13 8.7e-05 0.0072 17.0 0.8 1 23 379 401 379 401 0.98 4 13 1.8 1.5e+02 3.5 0.1 1 23 445 468 445 468 0.92 5 13 0.0046 0.38 11.6 2.1 5 23 776 794 773 794 0.92 6 13 0.053 4.4 8.3 1.4 1 23 800 823 800 823 0.98 7 13 0.001 0.085 13.7 0.7 1 23 903 926 903 926 0.97 8 13 0.0044 0.36 11.7 0.2 1 23 1190 1213 1190 1213 0.92 9 13 0.014 1.2 10.1 1.1 2 23 1226 1247 1226 1247 0.97 10 13 0.0042 0.35 11.7 1.0 1 23 1252 1275 1252 1275 0.93 11 13 0.0021 0.17 12.7 3.9 1 23 1281 1306 1281 1306 0.95 12 13 0.0043 0.36 11.7 4.1 1 23 1311 1333 1311 1333 0.97 13 13 0.0012 0.096 13.5 0.8 1 23 1339 1362 1339 1363 0.95
Sequence Information
- Coding Sequence
- ATGGCATCAAACAATAGGCTGAAAACGGGCTCAGGATCATCCGAAATTAACTACAAGTTTACATGTCGCTGCTGTCTGAAATCCGATGCGGAGTTCCTCAAGTTGGACTCGCAGTCGGTGGCGCGCAATCTGGATCAAAGCGAATCCGATAAAATACCCCTGCTGCGTTGTTTGCTGTTCTGCATACGCGCGGAAAATTCGCCGGAGCTGCCGCAATACATATGCGTTGAATGCAGCAAGAGCCTGCAAATAGCCTACTATTTCATGCAGAATGCACTACGCGCACACGAAATACTCTGCCGCAAACTGTGTCCGGGAAAACAGCGTCCTACGCTGGCACAGCGCTTCAATGGTTCCATCAAACAATCAGAGGTGGCGCCGCGGCAGGCGGGTGACGACAAGACGAAGCCACATAAGGCATTTCGGCACGAGTGCAAACTCTGCGGCTTTGTCGTCTACAATCGGATGGAACTAAAGCAGCACATTCGTCAGCACGTTGATGGGAGCTCCTACAGCTGCAAGGTCTGTAGCTTCGTTACCCTGAAGCAGCGTCTCCTGCAAGAGCACTACAGTGCGACCCATGGAATGTCAGGCAATCATGCGGATGGGCAAGGTAAACCCAAATCATTCTACAGTGCGGCCACATCCACTTCATCCGCATCCGCTGCGGCTCCCAAGGAGGAGGTTAAGGTGTGCACCCTGGAGGACATGGAGCTGTTGATTCCCACAGTTCTCACGCCCGGGGACTACATGCAACCGTCCATCGACGAAGAGCAGTTGCGCGACATCGAACAGCAATTGGCCGTTAGCATGGGAGAGCCCGTTGTCGGTGGCGAGACTCTGGCCTCCAACCTGACACAAATGGAGGGCAACAATATGAGCATCGGCACCGAGTATGTCGTGATGCCCGATGGTACCTTGCAGATCAACGGAGGCGGTGTGGTCATAGAATACATTGATGACAGTAGGCCAAATACCAACGCCACTGGGAACGTGAGTCTGCAAAATCTCCTTGGCAGCAGTCCCGAAAACGAGCCCATGGACATCGATGTCAGTGAGCTGATTGTGGAGGATGTGGTGCCGCAGATAAAAGTCAAGCCAAAACCAATATCCATTGGATCCGCTCCCCTCAAgtacaaatgcaaatcctGTCCCAAAGCATTTGTCACCCTGGCGCGTCTGAAATCTCACCAGTTAAGCCACAGCCATTTGCCCAAGTTCTACTGCGATCAGTGCCCCTTCTACTCGCTGCGCTCTGCCGATCTCTGCCAGCACTACAAGGCAAAACACCTGAAGAACGAACAGAATGGAAAGGTGACCGGCGATGTGACCTATGCCTGCGACACGTGCCTTTTCGAAGCGAGGACCGCCACACAGCTAGCGGTGCACATAACTGAAAAGCATAAGACTAAACCCTCGGATATAGATCTGCGCCCCACTTGGCAAAGCGAGTCGGGCACCTCCGGTGGCGCCATCAGCTCGGCCAGTACCAGTGGCCAGGAGCAGGGCCGTCAGCCACAGCAACCCGATATTCCCATGGGCATTCAATATCCATCTGCAGcgctggcggcggcggtgacAGTTGAAAATCAGCCATtgcatcagcatcaacagcaacagcagcaggagcaacagcagccgcaggagcAAAAGCAACTGCCAGCGACAGCAACGGAAACATCCACGATAACGCAGTCGGGCGAAATCAATGTGGTGGTAGATGCCACACCTTTGTTCTATACGACACCAACAACGACAGGGCCTAGCACTGGGACTGATACTGTGACTGGTACTGTGACTCGAACAGAATTAGAGGGCCAGGGTCAGGGAGATCCGGGTGCAATATCTGCGGAAGCAATGGCCAACGGAGAAGGGCTGCACATCGGCAGCACATATGAAATCTTTCCAGAAATCTCAACGAGCAGTCTGGCAGTGACTCAGCCCGTACCGGCGTTGCCAACGACAACGTCGGCGAACATCTCGATGTTTGGGGATATGCAGGATTTTATTGACAACACAGATGTGGCCGCCATATGCACCATACCCGCTGATGATATGCCCGTGGTAGATGGTGACGATATTGTAATTGATAATAACAACATCAGCTTGGACTTTGATGCTGAGAATCTGTTTGAGGACTTTGAGGATGACGAAGAGGCCGTTGGCGAGGAGgaagacgaggacgacgacgacgctgaGAATGAGGATGAAAATGACAACAATGATGCAGCAGCCGATCAGAATCTGCTGCTAAcaagcgacgacgacgatgtgGATGACTTTGACGACGAGCAATCCAAGCATCTGCAAAAACCCTACTGCATATTTTGCAACAAAAAGTTTACGAGCCAATACAAGTTCGAGAATCACATGTTTGTACATCGAGGCCTGGCCCCCTACCGCTGTGAGCTCTGCACCAATCTGTACAACATGAAGCGTCTCCTCATCAGGCACTACAAAACCGTACACAGGCGCATGCCCACGCGCGATATGGTCCAGGCGAAGGGCGACAAGGTATCGGTGGCCCGTACCAATATTGAGACAATACAATTGGATCAAGACAGGAAGCCCATGCTGATGTGTGCCAAGTGTCCGTTCGAGTGTGAATTGGATGCGGAAATGCGAAAGCATTTGAATGCCCATCACGGCATCAATGATGGTGTATCCGTGCATGCCAACGAGGTGTTCATTATCCGCAAACTACCCTTTGAGTGTCCGCGATGCATTCGCTCATTTGCGGCCAAGAGCACACTGACCCGCCATCTGCAGCGTAGCCATTTGGTGGACACGATAATTGAGATGCAATCcaaccaaacaacaacaaactcGGCAGCCACAACCACAAGTACCACGTGCACAGCCACCAACTCATTGCCGGCGAACACGGCTGACGATAATGGGAATAAAGGGCAGCAGCTCGAGACAGATCGACCGGCAACGTCGGACACGGAGACGGTTGGTTATGGCGATGGGGAATGCGAGGTAGCTGTCAAACCTGAAGGCGCAACGACAACAGCAGCCGGAGCTAAAGAAGAGCCAACGACTAGTTCAGCCGCATCCGCATCATCATCCATAAGATCAACCATAAAAGCAGATCCAGCATCAGAAAGAATTCCGAATCCCCCCGACGAATCGTCAGAGCCACGAGCCATGAACAGCATAGATTATATTCCAGTCAAGGGCGAGACAGGATCTGCGGGAGAAAAAGCATCACCACATACCGCCACAATGGCGTCATCGTCATCCACACCAACGccatttgattttgattttgattttatgGGGGAAGCACGAAAAACTCGGCTTACGCCTACTCCCACCAAGCACAGTACGCCCAACAGTAAGGGCAACAAACAAATCGTCAGCACCACAGAACAGTTCCCTTGCACCACCAATCCGAGCACGAGCACCACCATCGttagcaccagcaccagcattAGCACCAGCACCATCACCAATGACTTTGCATCGAGCGTCCTACTGAACGGCAGCGACAAACTGTTGACTGCCGCAATGGAGCCATCGCCTATTAAAGGCCTACGTCCGCGCCTCCCTCGTGCCCCAAACTACGCGTGCAAGCTCTGCAAAAAGAGTTTTGATGAGCTGGGAAAGCTGGTAAAGCATGAGATGGATGCGCATACCATTGGCCAATCGCCACGCTTGGGCTATGAGAACAGGTGTGGCACCTGCGGAACAACGTACCGCACAGTAGCGCTGCTTAAGTTCCACATGAAGCGGCATTTGAACCGCAAGTTTCAGTGCAAGCTTTGTGCAAAGGAATTCGTATACAAAACTGAATTGGACAGGCACAAGCTGGCCAAACATGCCACCGAGAAGTCGTTCCGATGTACTCTGGATGGCTGTCGCAAGATGTTCGCCTTCAAGCATCATCTGGTGCGGCATCAGAATGCATCTCATCTGAAGTTGCGCCATGTGTGCGCGATATGCCAGAAAGAGGTGAAGACCAGCCTGCATCTGAGGCACCACATGACCGTGCACAGAGGCATGACAGCCTACAAGTGCCCCAAATGTGACCGCACATATTTACGTCGAGGAGCCCTTCGTGTCCATGCACTGTCCGTGCATCATGTGCAGCTTACGGAGACAGAACTGGCAGAAGTCTTTCGCAACAACGTGGGCTATACCAATCCGCACGACATGAAGGTATTCACACGCAATGGGCAATTGGTGCGCCGCAAGGAGCTGGAGGCCGGAAGAGAAAGGGAAATGCAGATGGGCGACGAATCATCCACGGCAGTGGcgaatatttcaaaataa
- Protein Sequence
- MASNNRLKTGSGSSEINYKFTCRCCLKSDAEFLKLDSQSVARNLDQSESDKIPLLRCLLFCIRAENSPELPQYICVECSKSLQIAYYFMQNALRAHEILCRKLCPGKQRPTLAQRFNGSIKQSEVAPRQAGDDKTKPHKAFRHECKLCGFVVYNRMELKQHIRQHVDGSSYSCKVCSFVTLKQRLLQEHYSATHGMSGNHADGQGKPKSFYSAATSTSSASAAAPKEEVKVCTLEDMELLIPTVLTPGDYMQPSIDEEQLRDIEQQLAVSMGEPVVGGETLASNLTQMEGNNMSIGTEYVVMPDGTLQINGGGVVIEYIDDSRPNTNATGNVSLQNLLGSSPENEPMDIDVSELIVEDVVPQIKVKPKPISIGSAPLKYKCKSCPKAFVTLARLKSHQLSHSHLPKFYCDQCPFYSLRSADLCQHYKAKHLKNEQNGKVTGDVTYACDTCLFEARTATQLAVHITEKHKTKPSDIDLRPTWQSESGTSGGAISSASTSGQEQGRQPQQPDIPMGIQYPSAALAAAVTVENQPLHQHQQQQQQEQQQPQEQKQLPATATETSTITQSGEINVVVDATPLFYTTPTTTGPSTGTDTVTGTVTRTELEGQGQGDPGAISAEAMANGEGLHIGSTYEIFPEISTSSLAVTQPVPALPTTTSANISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDDEEAVGEEEDEDDDDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHRRMPTRDMVQAKGDKVSVARTNIETIQLDQDRKPMLMCAKCPFECELDAEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLTRHLQRSHLVDTIIEMQSNQTTTNSAATTTSTTCTATNSLPANTADDNGNKGQQLETDRPATSDTETVGYGDGECEVAVKPEGATTTAAGAKEEPTTSSAASASSSIRSTIKADPASERIPNPPDESSEPRAMNSIDYIPVKGETGSAGEKASPHTATMASSSSTPTPFDFDFDFMGEARKTRLTPTPTKHSTPNSKGNKQIVSTTEQFPCTTNPSTSTTIVSTSTSISTSTITNDFASSVLLNGSDKLLTAAMEPSPIKGLRPRLPRAPNYACKLCKKSFDELGKLVKHEMDAHTIGQSPRLGYENRCGTCGTTYRTVALLKFHMKRHLNRKFQCKLCAKEFVYKTELDRHKLAKHATEKSFRCTLDGCRKMFAFKHHLVRHQNASHLKLRHVCAICQKEVKTSLHLRHHMTVHRGMTAYKCPKCDRTYLRRGALRVHALSVHHVQLTETELAEVFRNNVGYTNPHDMKVFTRNGQLVRRKELEAGREREMQMGDESSTAVANISK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575090;
- 90% Identity
- iTF_00484653;
- 80% Identity
- -