Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:5668944-5672113[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.1e-05 0.0042 17.8 4.8 1 23 175 198 175 198 0.97

2 16 0.00029 0.024 15.4 2.0 1 23 233 256 233 256 0.96

3 16 0.0052 0.43 11.4 5.9 1 23 321 344 321 344 0.96

4 16 0.00069 0.057 14.2 1.1 2 23 402 423 401 423 0.97

5 16 7.1 5.9e+02 1.6 1.1 1 20 536 555 536 557 0.88

6 16 0.015 1.3 10.0 0.5 1 23 566 588 566 588 0.94

7 16 0.00019 0.016 16.0 0.7 1 23 595 618 595 618 0.96

8 16 0.00079 0.066 14.0 0.8 2 23 627 648 626 648 0.95

9 16 0.0038 0.31 11.9 0.1 2 20 675 693 674 698 0.90

10 16 0.0069 0.57 11.1 0.7 1 23 733 756 733 756 0.95

11 16 3.1 2.6e+02 2.7 1.2 3 22 765 784 763 784 0.95

12 16 0.0066 0.55 11.1 1.5 1 23 793 816 793 816 0.97

13 16 4.1e-05 0.0034 18.0 0.1 1 23 838 861 838 861 0.97

14 16 0.039 3.2 8.7 0.2 1 23 871 893 871 893 0.94

15 16 6.6e-05 0.0055 17.4 3.7 1 23 899 921 899 921 0.99

16 16 6.9e-06 0.00057 20.5 3.2 1 23 927 949 927 949 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.1e-05	0.0042	17.8	4.8	1	23	175	198	175	198	0.97
2	16	0.00029	0.024	15.4	2.0	1	23	233	256	233	256	0.96
3	16	0.0052	0.43	11.4	5.9	1	23	321	344	321	344	0.96
4	16	0.00069	0.057	14.2	1.1	2	23	402	423	401	423	0.97
5	16	7.1	5.9e+02	1.6	1.1	1	20	536	555	536	557	0.88
6	16	0.015	1.3	10.0	0.5	1	23	566	588	566	588	0.94
7	16	0.00019	0.016	16.0	0.7	1	23	595	618	595	618	0.96
8	16	0.00079	0.066	14.0	0.8	2	23	627	648	626	648	0.95
9	16	0.0038	0.31	11.9	0.1	2	20	675	693	674	698	0.90
10	16	0.0069	0.57	11.1	0.7	1	23	733	756	733	756	0.95
11	16	3.1	2.6e+02	2.7	1.2	3	22	765	784	763	784	0.95
12	16	0.0066	0.55	11.1	1.5	1	23	793	816	793	816	0.97
13	16	4.1e-05	0.0034	18.0	0.1	1	23	838	861	838	861	0.97
14	16	0.039	3.2	8.7	0.2	1	23	871	893	871	893	0.94
15	16	6.6e-05	0.0055	17.4	3.7	1	23	899	921	899	921	0.99
16	16	6.9e-06	0.00057	20.5	3.2	1	23	927	949	927	949	0.98

Sequence Information

Coding Sequence: ATGACCCGGACCTGCAGAATCTGTGGCGATGCAAATGGACGCTACTGGGTCGAGACGCCGGTGGAGAAGTATGCCGGGAAGACCTTCAGTCAGATTTTGCTGGAGCTAACCAAGATTGAGTTGACCATGGTCCAGGCCGAGAAGTTGCCCCACTGGCTGTGCTCCAGTTGCTCCCAGAAGCTGGAGAGCGCCTACGATTTTGTGTTACAAGCCAAACAGACGCACAAACTGTGGCTGCAACAGCTGGAGGATACGGGGCAGATAATGAGCTCTGGGGGATCCTTGGAGTGCCTGCGGGAAACCCCCATACAACTGTTTGAGATCGAGGGAGCTGCCATCAAAACCGAAGCGTTAGAGTCAACGGTAGCAGATGCCGGGGAAAGCTCCTGCGATCCACTAGTCCGCACACGCATCAAAAAGCGTACCATCTTTCACTTCAGCGATACGGAAGATGACCAGGATGATGTACCGCTTCGGCAACGCAGGACGGGCAGCCAAGCGAACAGCTCATCACCAAAGCTGCACAAGTGCAATCTGTGCGGCAAATCCTTCAGATATATCACGAATCTCTATCGCCACAAGAAAAGAGATCACGGCTATCCAGGCCAACCAAAAAGCGAGAGCACCGAATCATACCCGGAAAAGACAAGTTCCAATTTGGAAAAaaacgatgatgatgaggatgatgacaGCTACTACAAATGCGATCAGTGCGACAAATCCTACAAGCACATAATTCTGCTTATCAAGCACAAGCAAAATGCCCATGAAGCTAGCCAACAGCCAATCCAATCTGGGTCCAAGCGAAGAAACAGAAGAGACGTGGGTGAGCCAGGAAGTCCAGCTCCTTCCGGGAAATACACACAACGAGCCAGAATCAGCACCGATACCCTGGTCCATAGCCTCATCAAAGAAGTGGAGCTGTCGGATGAGGATGGAAACAGCGGCAGCGATAACTACTACAAGTGCGATCAGTGCCACAAATCGTACAAATACATTGTAAGCCTCatcaagcacaagcacaaggaACATTCGGAAGCTGACAAAAACTGGGACGACGAGGACAATCAACCATTGGCCTCCACATCTGCCTGCGCCACTGCCACCTCTGGCTCAGGCTCTCCCACGAAGGCCTCGCGAATCAATCGTCGCGTTCAGGGCTTCGACCTGCATCGCTGCCAGCCGAATGGTGCGAAGGAAATTCAGTGCATGATCTGTCTGCGGAAATTCACTAAATTGCGTGAGCTGAGAGATCACCTCAGGTCGCATCCCACGGACTTCAATTTCCAGGCGCACGGTGAGCCCATCGAACGCATTGCCGAGGGTTTTTTTAAGACGGCTGTGGAGTCCACTGTGGAGGGTTTGAAGAGCAGAATTCTGCACGATCTAAGGATAGGTGCTTTCGGACGCTTCTATTCCATTACCAACGAGGCGCGCTACGAGATGAGTCTGGACAGCTCGGACACGGATAGTGATGGCGATGCAGATGTTGTACTGAGACGAAGCTATGCCTGCGAGCTATGCGACTCTCCGGAGGCCAGGTGGCCGCGCAAGTATCAGCTGCACGAGCATCACAGACAGCAGCACACCTGGGAAGAGGCTCCCCATGTCTGCCAGCGCTGCGACTCGCGTTTCCTCAGTCTCCAGCTGCTGGAGCATCATACCCTACAGCTCTGCCAGAACACTCTGAAGCGATACATGTGCGACAAGTGCCCGCAGCGCTTCTTCTGGCGAAGAAATCTGCGTGCCCATCTGGTGGAGCACAAGAGCAAGCAAGACAGCTATCCGTGCGACCAGTGCCAGCGTAGTTTTCAGGACAAAAGCGCCGTGACCAAGCACAAGCTGATGATGCATCGCGATGAAAAGAATCAGCTTATTCCCTGCCGCTGGTGCTCACGGACCTTCTATCGTCCCGCCCTTCTGCACAAGCATGTCGAACGGCATGGCTTCACCGGCGACGATTTGCCCCTGGCAGAGACATTGCTGGCCGATGCGGCCAAGCCATCGGGCCCAAAGACTGTCCAGTGCAAGATCTGTGACCTGCAGTTCGTAAGCGTGGCAGATCTGCGCCGCCACAATGCCATGCTGGGCCACAGTGAGCGTCTAACCGAGTACATGATCAGCACCGAGGCTGGCTTCGAGCTGTTGTTGGAGGACACAGATGACAGCGATGACGACACTACGGGGGGCAGGTCCTACTCCTGCGATCTCTGTCAGATGGCGTTCCGTCGCCGCAGGGAGATAAGCGAGCATCAGTATTCACTGCACGCCTTTGACAAGTTGCCATACGGGTGCAAACATTGCATTTATAAGACCGTCGATAAGCTCATGCTGGAGCATCATCTGCGCACACAATGCCTGAACAACGAGAAGCCGTTCAGCTGCTCCCGCTGCAAATACAAGTTCATGTGGAAGGAGAACCTGGAGCAGCACATGGCCACTCAGCATCCCAAGCAGCCGCCCACCCAAGAGCAGTCGGCCATGCCCTTGAGGAGGAGACGACGCTTCAGATATCAATGCCCACAGTGCTGGCGATCGTTTGTTGTGCAGCCCAGCCTCGATAAGCATATAAGGGACATGCATGTGGCCAAGAGGAATCCGGGCAAGAAATACCTCTGTTCCCTCTGTGGCTTGGAGTCGCTGACGCCCAACAAGCTGAACATCCATATGCGTCGCCACAACGGCGAAAAGCCCTTCAAATGCGATCTCTGCGACATGCGCTTCACAGTCCACTACGAGCTGAAGGTCCATCGACGGAAGCACACCGGCGAGCGGCCCTACCAGTGCACTTTCTGTGACAAGCACTTTGCGCGACCCGACAAACTCAGACGGCATGTCTACATGCACAGTGCTCGTCGCTAG
Protein Sequence: MTRTCRICGDANGRYWVETPVEKYAGKTFSQILLELTKIELTMVQAEKLPHWLCSSCSQKLESAYDFVLQAKQTHKLWLQQLEDTGQIMSSGGSLECLRETPIQLFEIEGAAIKTEALESTVADAGESSCDPLVRTRIKKRTIFHFSDTEDDQDDVPLRQRRTGSQANSSSPKLHKCNLCGKSFRYITNLYRHKKRDHGYPGQPKSESTESYPEKTSSNLEKNDDDEDDDSYYKCDQCDKSYKHIILLIKHKQNAHEASQQPIQSGSKRRNRRDVGEPGSPAPSGKYTQRARISTDTLVHSLIKEVELSDEDGNSGSDNYYKCDQCHKSYKYIVSLIKHKHKEHSEADKNWDDEDNQPLASTSACATATSGSGSPTKASRINRRVQGFDLHRCQPNGAKEIQCMICLRKFTKLRELRDHLRSHPTDFNFQAHGEPIERIAEGFFKTAVESTVEGLKSRILHDLRIGAFGRFYSITNEARYEMSLDSSDTDSDGDADVVLRRSYACELCDSPEARWPRKYQLHEHHRQQHTWEEAPHVCQRCDSRFLSLQLLEHHTLQLCQNTLKRYMCDKCPQRFFWRRNLRAHLVEHKSKQDSYPCDQCQRSFQDKSAVTKHKLMMHRDEKNQLIPCRWCSRTFYRPALLHKHVERHGFTGDDLPLAETLLADAAKPSGPKTVQCKICDLQFVSVADLRRHNAMLGHSERLTEYMISTEAGFELLLEDTDDSDDDTTGGRSYSCDLCQMAFRRRREISEHQYSLHAFDKLPYGCKHCIYKTVDKLMLEHHLRTQCLNNEKPFSCSRCKYKFMWKENLEQHMATQHPKQPPTQEQSAMPLRRRRRFRYQCPQCWRSFVVQPSLDKHIRDMHVAKRNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSARR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575022;
90% Identity: iTF_00481028;
80% Identity: -