Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:8562601-8564571[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.092 7.7 7.5 0.3 1 21 299 319 299 320 0.95

2 10 3.4e-06 0.00028 21.5 0.2 1 23 328 350 328 350 0.98

3 10 0.0016 0.14 13.0 0.3 1 23 353 376 353 376 0.93

4 10 1.3e-06 0.00011 22.8 1.0 2 23 383 404 382 404 0.98

5 10 2e-07 1.7e-05 25.3 1.3 1 23 410 432 410 432 0.95

6 10 2.4e-06 0.0002 21.9 0.9 1 23 438 460 438 460 0.99

7 10 0.017 1.4 9.8 4.0 1 23 466 488 466 488 0.98

8 10 0.001 0.085 13.7 0.3 1 23 494 516 494 516 0.98

9 10 0.00023 0.019 15.7 3.9 1 23 522 544 522 544 0.99

10 10 0.0018 0.15 12.9 0.0 1 23 550 572 550 572 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.092	7.7	7.5	0.3	1	21	299	319	299	320	0.95
2	10	3.4e-06	0.00028	21.5	0.2	1	23	328	350	328	350	0.98
3	10	0.0016	0.14	13.0	0.3	1	23	353	376	353	376	0.93
4	10	1.3e-06	0.00011	22.8	1.0	2	23	383	404	382	404	0.98
5	10	2e-07	1.7e-05	25.3	1.3	1	23	410	432	410	432	0.95
6	10	2.4e-06	0.0002	21.9	0.9	1	23	438	460	438	460	0.99
7	10	0.017	1.4	9.8	4.0	1	23	466	488	466	488	0.98
8	10	0.001	0.085	13.7	0.3	1	23	494	516	494	516	0.98
9	10	0.00023	0.019	15.7	3.9	1	23	522	544	522	544	0.99
10	10	0.0018	0.15	12.9	0.0	1	23	550	572	550	572	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATTTGCCTGACCTGCTTAAGTCTGAATGGGCCGTTTCTATCCATTTATGAGGGCGGAGTAGGCAGCTGCCTGGCCGATATGCTCAAACAATTCACAAAAACCAAGCCGCGCCCCGAGGATAATCTTCCCAAACGGGTGTGTCTGAGCTGTCTGAGCGAAATCAACCACTGCTACACGTTCAAGATCAAGTGCGAGAACTCAAGTCGAACTCTTCGCCAGCTGCTGCCAAATGCCTTGCCGGAGGAGCCTGATTTCGCCCCCACGAAGTCTGTGGACTCTGCCGAGAAGGCCGTACAGACCACCGAATCCTGTGCCCCGacaacagccacagctgcAGTGCAGACCACAACGGTGCCCACCACAGATGCCGCGCAGAACACCAGCCTGGATaggtctgcctctgcctccgaaGACGAGGATGCAGACGAAGACGGTGAAGGGTGCGAGGTTTTTGATTACGAGATACCCGTAGAGGCTGCTGAAAAGGAAGATGATAAAGACACCACCGAGCCCGAGAGTCAGAAGATAACAGAATGTAATATAGCTCTATTCGAGGCTGCCGACAGCGACACAGAGACACCAGAACCCGCACAGGCTACCAAACCACAGTTGAGGACACGAAAAAGTGTCGCCAAACTGCTGCTTcaaaagcaggagcaggagcaggtgAAGCAGTCACCCAAGCGGGAAATAGAAGACTCACAGCCaccgacagagacagagccagaggcagaatCTCAGACAACACCCGCCAAGAGAACCTCACGACGTCGCCCAGCCGAAAAACAAACTGAAGATCAATCCGCAGTACAAATGGTGGCTCCGGTGCCAAAACTGATGAAACTCAGCATCACCCATGGAGAAATAATGGATCTAAAGTATCATTGTGATCGCTGCAATGCTGGTTTTGCCTTGGAGAAGTCCCTAATGATACATCGTCGACAGAAGGGTTGCATCAATCGTAATTTTCCCTGCAACGAGTGCGAGCGGGTGTTCGTTTCCTCCGAACATCTTGCCGAGCATCAGGCCACCCATGGAACGTTCAATTGCCAGGAGTGTGACCTGCAGTACGACTCCAAGGAGCAGCTGGGTAAGCACATGGTGCAGGGTCACAAAAGGAATCTGCGCAATCAGTGCAATGTTTGTAAGAAGGTTTTTACCATGCTATCGACCCTGCGGGATCACATGCGCATCCACACCGGGGAGAAGCCATTCCTGTGCAACATTTGTGGCAAAAGCTTCACCCAAAATGCCAATCTGCGGCAGCACAAGCTCCGCCACTCAGACATCAAGCGTTTCAAGTGCGCCGAGTGTCCGCATTCGTTTGTGACCAAAGCGGAGCTGACATCTCATGCCCGCACCCACTCCGGCGTCAAGCCGTTCGAGTGCGAGGTGTGCATGTCCAGGTTTACGACAAGCTGCTCACTGGCCAAGCACAAGCGTAAACACACCGGGGAGCGACCCTATGCCTGTGACTTGTGTCCCATGCGCTTTACTGCGCTCAATGTGCTCAAGAATCATCGACGCACCCACACCGGAGAGCGTCCCTATGTGTGCCCCTTCTGCTCGAAGACCTTCACACAACGCGGCGATTGCCAGATGCATCAGAAGACCCATCAGGGCGACAAGATCTACATTTGTCCGGTGTGCAGCGAGGAGTTCAAATCAATGCCAGAGATGCGCACACATTTGGCCATACACGAGCAGGAGGACAAGCGCTTAATGCACTTTACGCTGCTCAGCAACAAGGAGAATGGGAGTGGGGGGGCCCTGGACGATGAGCTCACTGAAGTGACTGATTCGGCATTGATGCTATAA
Protein Sequence: MDVEKICLTCLSLNGPFLSIYEGGVGSCLADMLKQFTKTKPRPEDNLPKRVCLSCLSEINHCYTFKIKCENSSRTLRQLLPNALPEEPDFAPTKSVDSAEKAVQTTESCAPTTATAAVQTTTVPTTDAAQNTSLDRSASASEDEDADEDGEGCEVFDYEIPVEAAEKEDDKDTTEPESQKITECNIALFEAADSDTETPEPAQATKPQLRTRKSVAKLLLQKQEQEQVKQSPKREIEDSQPPTETEPEAESQTTPAKRTSRRRPAEKQTEDQSAVQMVAPVPKLMKLSITHGEIMDLKYHCDRCNAGFALEKSLMIHRRQKGCINRNFPCNECERVFVSSEHLAEHQATHGTFNCQECDLQYDSKEQLGKHMVQGHKRNLRNQCNVCKKVFTMLSTLRDHMRIHTGEKPFLCNICGKSFTQNANLRQHKLRHSDIKRFKCAECPHSFVTKAELTSHARTHSGVKPFECEVCMSRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQKTHQGDKIYICPVCSEEFKSMPEMRTHLAIHEQEDKRLMHFTLLSNKENGSGGALDDELTEVTDSALML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00484572;
90% Identity: iTF_00580913; iTF_00536203; iTF_00574992; iTF_00517879; iTF_00484572; iTF_00473949; iTF_00481001;
80% Identity: -