Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:14646428-14649499[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.7e-08 8.1e-06 26.3 1.8 1 23 212 235 212 235 0.97

2 17 0.0033 0.27 12.1 0.4 1 23 242 264 242 264 0.98

3 17 0.23 19 6.3 0.1 2 23 296 317 295 317 0.94

4 17 2e-05 0.0017 19.0 1.7 1 23 409 432 409 432 0.97

5 17 0.29 24 5.9 0.5 1 19 439 457 439 460 0.94

6 17 0.027 2.2 9.2 5.2 1 23 469 491 469 491 0.95

7 17 2.2e-05 0.0018 18.9 0.7 1 23 498 521 498 521 0.97

8 17 0.00044 0.037 14.8 2.6 2 23 529 550 528 550 0.96

9 17 0.01 0.85 10.5 0.0 2 21 577 596 576 597 0.94

10 17 0.012 1 10.3 3.8 1 23 646 669 646 669 0.98

11 17 9.4 7.8e+02 1.2 3.4 1 23 706 728 706 729 0.90

12 17 0.00014 0.011 16.4 1.6 2 23 759 781 758 781 0.95

13 17 0.00012 0.01 16.6 0.2 1 23 795 817 795 817 0.95

14 17 0.00014 0.012 16.4 1.1 1 23 823 845 823 845 0.99

15 17 3.6e-07 3e-05 24.5 2.3 1 23 851 873 851 873 0.98

16 17 4e-05 0.0033 18.1 3.8 1 23 879 901 879 901 0.97

17 17 0.0005 0.042 14.6 0.4 1 22 907 928 907 931 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.7e-08	8.1e-06	26.3	1.8	1	23	212	235	212	235	0.97
2	17	0.0033	0.27	12.1	0.4	1	23	242	264	242	264	0.98
3	17	0.23	19	6.3	0.1	2	23	296	317	295	317	0.94
4	17	2e-05	0.0017	19.0	1.7	1	23	409	432	409	432	0.97
5	17	0.29	24	5.9	0.5	1	19	439	457	439	460	0.94
6	17	0.027	2.2	9.2	5.2	1	23	469	491	469	491	0.95
7	17	2.2e-05	0.0018	18.9	0.7	1	23	498	521	498	521	0.97
8	17	0.00044	0.037	14.8	2.6	2	23	529	550	528	550	0.96
9	17	0.01	0.85	10.5	0.0	2	21	577	596	576	597	0.94
10	17	0.012	1	10.3	3.8	1	23	646	669	646	669	0.98
11	17	9.4	7.8e+02	1.2	3.4	1	23	706	728	706	729	0.90
12	17	0.00014	0.011	16.4	1.6	2	23	759	781	758	781	0.95
13	17	0.00012	0.01	16.6	0.2	1	23	795	817	795	817	0.95
14	17	0.00014	0.012	16.4	1.1	1	23	823	845	823	845	0.99
15	17	3.6e-07	3e-05	24.5	2.3	1	23	851	873	851	873	0.98
16	17	4e-05	0.0033	18.1	3.8	1	23	879	901	879	901	0.97
17	17	0.0005	0.042	14.6	0.4	1	22	907	928	907	931	0.90

Sequence Information

Coding Sequence: ATGAGGCTGCCAGTAGTTTGTCGGACCTGCGATTCGACAGATGCTGATAATCTTTTGAAGCTGGCCACTCCCACCAAAAAGTACCCAGACAAATTGCTTTCGGACCTCTTAAGCGAGCTCACCGACATTAATCTGGACACATCTGCTAACCAGAGGCTTCCACAGTGCTTGTGTAGCAGTTGCACCAAGAAATTGATGGGTGCCTATTGCTATGTTAGGCAGGCGCTGGCCGCCAATGACCTCTTGCTAAAGCACCTGAAAACTGACTGCTTGCAAGAAACGCCTATGGAACTGTGTGCGGAGCAGCATGTGATGGTGAAACTAGAAACAGAGGACGAGGATGGGGGGGAAACTGAAAAAGACATAAATTGCTCCGGGCTACCTGAAATGGTCCCAGAAGAAAGTCCAGACGAAAAAGACTTCGACAACAAGAAATCTGTTGATCCATTAATAATGATCGATTCTGTCAAGCAGGAAACTACTGTCCAGGCCAGGATAGAAAAGCATGTAGATGACGAAGCCGTGTCGGACTTTGAGGACGAAGACTCGCTGGATGACTTGCCACTGGGGCAACGCATACAAAAATGGAAGACGAGAAATGGTGATTCCCTGCGAAGCTTGAACCTGCCGATTTACAAGTGCAGTAAATGCCCAAAGAGTTTCAAACGAGCCGATTATCTGAAACGACATCAAATCAGAGCTCATAAGCCAGAATTGCGTTGGTTCTCCTGCTCACTCTGCATCCGAAAGTTCAATAGCAGTGAAGCCTTGGAAATGCATCTCAAAGTTCATCGAAATTCCAAACGCTCGGCGAATATAAGTGAGCATAAAAAGGCCAAGGCTGTGGATCTAAATCTTTGCAAACCCCATGGTTACAAGCTCATCGAGTGCATGATCTGTCAGAGTCAGTACAACAAGATTGCTGATCTGCGACGCCATTTGGAGGAGCACCCGGAAATCATTTCCATGGGATTGCGCCCGAATATGGAACCCAATGAGCTGGCCGAGTTGTTCTACCCCGATAGGTCCGATGCCAAGGATGTTGGCGAGGATCAATTAATTGACTTGATTCGCAAAGATTTGGAAGGCGGCATTTATCATCGCTTCTATTCAATAACTAATCAGTGTGGTTATGAAATGAACCTAGACAGCTCTGACACTGACAGTGAGCTAGACGTGGATGCCGAAGATCAACAGAAGAAGCGAAAAACTAGAAAGGCGCAGTACAGCTGCGAGCTGTGCCAACAGAGCTTTACCAGGAAGTATCTACTCTATGATCATCAGCGCCTATTGCACAGCTGGTCCGAGGCACCTCATGTTTGCGGCCGTTGCGATGGGCGCTTTGTCAGCTTGCAGATGCTGAGGCATCACAATGAGTCCCAATGTAGAAATTCGCAGAAACGATTTCTTTGCCACAAATGCCCTCTGCGATTTCGGTGGAAGCACAACCTAAGAGCCCACTTCCGAGAACATCGAATCACTAATCAAACATTTGAATGTTCCGAATGCAAGCGTGTTTTTGACAAGAAAAAATCTCTGACTGTTCATTTACTCAGCGCCCATGCTGAGGAATCGAAGCTCATTCCGTGTCAGTGGTGTACGCGCAAGTTCTATCGCCATGACTACCTGGTGAAACATCTAAAGCGGCATGGACTCAAGGAGCAGGACATTCCGTTGGCCGAGACCCTGATTGCAGCCACATCGAAGCGAAATGGAGCCAAGCGCATTACCTGCAAAATTTGCAACCTGGATTTTGAACGCGTTATAGATTTGCGTGCCCACATTCAACTGGAATTAAAGCTATCTCTCTCGCTGCACCATAGCTACGAATCCCCGCATAACTACTCTATAACCAATGAATCCGGCTTTGAGATGCAGCTTGACGACTCGGAAACAGAAGACGAAATACAGCCTGGGTCTAGCAACCGTCCTCCCTACGTCTGCGAGCTTTGCAGTGTCCAGTGCAAGCGCAAATTCGAAATGTTTCAACATCAACGAACCATGCACCGATTCGACAAAATGCCTCATGAGTGTGATAAATGCGTTTTTAAGTGTGTGTCCAAGaatattATGGATCATCATCTTCTTTGGCAATGCAGCAGCACAGAAAAGAAGCATGCGTGTAGCAAGTGCTCCTATAAATTCATGTGGCCTGAGAATAGGGATAAGCATGTGCGGCTCCACCATAGCGAAGTCTCCGAAAGCAGCAAAGCAGCCAAGCCGACGAGTGGTCTTGCCGATATGGACGCCTCAGAGGACGGGGTCCAGCTGCTACAATGCCCGCACTGTGATCGCACCTATCAAATGAAGTCGCGATTGAACAACCACATTAGGGACGTTCATGTAAATGGCGATCGAAAGCGCAAGGATGCGATCAAGAGATTCCTTTGCTCGCTTTGTGGCAGAGAAACACGTTCAGCTGCCGCTCTGGTTACCCACATGAGACGCCACACCGGCGAGAAACCCTTTAAATGTGATCTATGTGAAATGGCTTTTCCGAGACACTCGGAAATGGCTTCGCATCGCAGGATGCATACGGGGGAGAAACCATTCCACTGCACAGTTTGTGGCAAGGACTTTGCCCGGTCCGACAAACTGACGCGGCACATGCTCACCCACAGCGGATTGAAGCCGCACAAGTGCACGTACTGCGAGAAGAGCTACCGGCAAGCCAAAGATCTGAAGCTCCACTTGCAGCAGCACACAGGCGAATGTCCGTTTATCTGTGGCACTTGTGGCGAACGCTTCATACAAAATATCACTCTAGAGAAGCATCGACTAATGCGCCGCCATTTCGATTGGAGTTTGTCATAA
Protein Sequence: MRLPVVCRTCDSTDADNLLKLATPTKKYPDKLLSDLLSELTDINLDTSANQRLPQCLCSSCTKKLMGAYCYVRQALAANDLLLKHLKTDCLQETPMELCAEQHVMVKLETEDEDGGETEKDINCSGLPEMVPEESPDEKDFDNKKSVDPLIMIDSVKQETTVQARIEKHVDDEAVSDFEDEDSLDDLPLGQRIQKWKTRNGDSLRSLNLPIYKCSKCPKSFKRADYLKRHQIRAHKPELRWFSCSLCIRKFNSSEALEMHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIISMGLRPNMEPNELAELFYPDRSDAKDVGEDQLIDLIRKDLEGGIYHRFYSITNQCGYEMNLDSSDTDSELDVDAEDQQKKRKTRKAQYSCELCQQSFTRKYLLYDHQRLLHSWSEAPHVCGRCDGRFVSLQMLRHHNESQCRNSQKRFLCHKCPLRFRWKHNLRAHFREHRITNQTFECSECKRVFDKKKSLTVHLLSAHAEESKLIPCQWCTRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSKRNGAKRITCKICNLDFERVIDLRAHIQLELKLSLSLHHSYESPHNYSITNESGFEMQLDDSETEDEIQPGSSNRPPYVCELCSVQCKRKFEMFQHQRTMHRFDKMPHECDKCVFKCVSKNIMDHHLLWQCSSTEKKHACSKCSYKFMWPENRDKHVRLHHSEVSESSKAAKPTSGLADMDASEDGVQLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKDAIKRFLCSLCGRETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSEMASHRRMHTGEKPFHCTVCGKDFARSDKLTRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQNITLEKHRLMRRHFDWSLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487433;
90% Identity: iTF_00611484;
80% Identity: -