Dacu005664.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila acutilabella
Gene Symbol
RREB1
Assembly
GCA_035046005.1
Location
JAWNOK010000020.1:3792560-3799215[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.014 1.1 10.1 0.9 1 21 247 267 247 269 0.93
2 13 0.00034 0.027 15.2 0.2 1 23 279 301 279 301 0.98
3 13 8.3e-05 0.0064 17.1 7.3 1 23 307 329 307 329 0.98
4 13 0.13 10 7.0 1.1 2 20 542 560 542 562 0.93
5 13 0.51 40 5.2 0.1 1 23 721 743 721 743 0.97
6 13 1.3e-05 0.00098 19.7 0.7 1 23 753 775 753 775 0.99
7 13 0.00085 0.066 13.9 2.0 1 23 781 804 781 804 0.97
8 13 0.003 0.24 12.2 2.0 1 23 1085 1108 1085 1108 0.95
9 13 8.8e-05 0.0069 17.0 0.3 2 23 1447 1468 1446 1468 0.97
10 13 0.15 12 6.9 6.3 1 23 1474 1497 1474 1497 0.97
11 13 4.6 3.6e+02 2.2 3.6 1 23 1628 1651 1628 1651 0.79
12 13 0.0086 0.67 10.8 0.5 3 23 1720 1740 1718 1740 0.96
13 13 0.0014 0.11 13.3 4.8 1 23 1746 1768 1746 1768 0.99

Sequence Information

Coding Sequence
atgctggccacacagcaacaacacacaacagcgacagcagcgacaacaacaggcagcaacagcagcagcgctgccagcgTCGTCGAAATGGAACGCCAGCGTCGCGACTCAAGCACATCCGAATCGTCGCTAGAACATCTCGACCTAGGACGCACACCAAAGaagctcagcagcagcaacggtgCACCGCAGCCGACGTCAACGCCGCACGAAATAACAGcgacgacagcgacgtcgCGCAAGCGTAAGCtacgccagcagcagcagcaacaacacttgCTCTCcgacgaagaagaagagcaaaagcaacaacaacaacaacagccatcGGAATTGTCTGCGCAGCGACCGCGTCACAAGCAGCGACGCAATGCCGCTGCCAGCGCCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCTAGTTCACTGCGCAAAAAATTTCGTCTGAATCGTAGCAGCGCTGTCGGTAGCGAACTGTCCGAATCGGGTTTTGTTGATGGCAGCGCACATAGCGGTTATTTGCTCAGCAGCAGCGgtagtggcagcggcagcagcagtgccGGTAGCAGCGCACAATCAGCGGCCATCGCTGCCGCTGTGGTAGCAGCGCAgcaagtagcagcagcagccgcatcGGCGTCAGCGTCAAGCAGTTCGGGTGGCTCATCGCCAAACGGTAATTTGTGTTTATCGAGCGCCGAATCGGGTATTGGTGCCGGCGAggatcaaatgaaatttttatgcCCCATTTGTGACGTCGTCTCGGCCACGCCCCATGAGTTCACCAATCACATACGTTGTCACAACTACGCCAACGGCGACACGGAGAATTTCACCTGTCGCATCTGCTCAAAGGTGCTGTCCTCTGCTTCATCACTGGACCGACACGTGTTGGTGCACACGGGCGAGCGGCCTTTCAATTGCCGTTATTGCCATTTGACATTCACAACGAACGGCAACATGCATCGTCACATGcgaacacacaaacagcatcagacaacacagcagcaacagcagcaaacacagcagcagcagcaacaacagcagcagcagcaacagtcgcaATCACAACCACAgtcccagcagcaacagtcacagcagcaacagttgtcgTCGCGCCGCCAGCAACAGTCGGCGACAGCAATTGCTGTGCGTTCCGAGAGCTACGAAAGTGACGCAAGTTGCTCAACGGACGTGTCCAGCGCCCAAAGTCACAGCAGcaatcacagcagcagcagcaatcactccaacaacaacaacaacaataacaagctaagtaacaacaacaacaatactgAGGAGCAGCTGGCAACTCTAGGCGGCAACTCTAAGCGACGCCATAAAaccaacatcaacaacaacaacatcatggAAAAAGAGGAGCTGGAAGCggatgaggaggaggaggagctgGACAACTTGAGTGATGATGTGGCACAAATGATCACCTCCACACCAGATGTGGCAACGCTGCTCGCCTCAAATGCCACCACACCGAGTCCCTCGCCAGCACCAGCTGCCATGATGCTGCTCAGCTGTCCCGCCTGCAATGCCGATGATTTCGAGACATTGCCAGCACTGTGGCAACACCTGGATGAGCAGCACGCGGATATACCCGCCAAGTGTCGCGAATGCGAGGTTATTTTTGCTACACACCGACAATTGCAGGCACATGCGTGCAATGGCATGCAAATGTTGCCGCTACTAGGAGTTAGTTCCAGTCCGAAGCGGGAAGAGTTGggcgaggaggaggaggagcgcgaggcggaggaggaggagcgTGAGCAGGATGAAGAGGAGGAGCTGGAGGAAGCTGAGCGTGAGCAAACGAAACGCGATGATTTCTTTCAACAGCTGTACCTCAAGGGCAAGCACAGCGCACCCGCCGGCAACAATCAAACGCTGcccatgttgctgctgtcccCCATCAAACGTGAACCCTCGGAGCGTGCTGATAACCGACAGGATCTGGCTGACATACAGAGCATACTCAACATGACCAGCTCCAGCTGTACCTCCAGTTTTCTGCGCAACTTTGAGCAATCGGTCAACACTCCCTGCTCCTCCAGTCAGTACAGTCTGGACGGTCGTGATGCCGATGAGGAGGCACAGGATGTGTTCACCAGCGAATTCCGTCGCATGAAACTGCGCGGTGAATTCCCCTGTAAACTATGCATTGCAGTGTTTCCCAACCTGCGTGCCCTCAAAGGTCACAATCGTGTGCACCTGGCGGCAGTGGGACCCGCAGGTCCATTCCGCTGCAACATGTGCCCCTATGCGGTGTGCGATAAGGCGGCGCTGGTGCGGCACATGCGCACGCATAACGGTGATCGACCTTATGAGTGTGCCGTGTGCAATTATGCATTCACCACCAAGGCTAATTGTGAGCGACATTTGAGGAATCGTCATGGTAAGACCAGTCGCGAGGAGGTTAAACGTGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGTGAGGAGTCCAAGGCGTTGGGCGGACAACGTATGGGTGATGCCGACTTAGCTGAGTTGAGTTACCGCTCGATTTCACCGCCGCCCGTGGAGCCAGTGTCGCAGCTGAAGCACATGTTGCTCGCAGAGGCCACAACAACATCGGGTGCAGCGAGCAACAGCGTGAGCACAGCTGCTGTTAAGACGGCTCCCTCGAAAATACAAGTCAAGAGCTTGGATCAGCTGGTGGATAAACCTTTGGCGCCTGTTCTGGACTTGAGCATGGACGTCTTGGACTTGAGCAAGAAGCCCACAGCAACACatgagctgcagcagcaacagcagcaagaacagcaacagcaactgcagcagcaacgcgCACACGAGCGTGAACTTGAGCGTGAGCATGAATTGCTGttgtcacagcagcagcaggtacatcagcagcagcaacaggcacagcagcaacagcaactgtttgGCGCTGGCGATGCTGCCACGCAGTACATGCAGCAACTGTTTCGCAATCTGATGTTCCAACAGTCGCCAGCATTTCCGTTCTTTGGTTTCATGCCacccacagcagcagcggaaaagtctgcagcagcagccttGCCCGCCACGGCAGCAACATCGAGCGTTACGCCAGCAATTGCTGCCGCTAACTTGGCACTGCCGCTGCCCACGGGCGTGGGAGTGGGTGTgcccgtgcccgccggtggtccCGTCAAAATGGTCATCAAAAATGGCGTCTTGATgccgaaacaaaaacagcgtCGCTATCGCACCGAACGACCCTTTGCCTGCGAGCATTGCTCGGCGCGTTTCACGCTGCGCTCGAACATGGAGCGTCATGTGAAGCAGCAACATCCACAATTCTATGCACAGCGACAACGCAGCGGTCATCATGTGATGCGCGGACGTGCAGCAGCTTCCTCcacggcagcagcaaatgccgccgctgcagcagcagcagcagccgccgcggcagccgcagcagcaatgTCCAACCTcagccagcagcaacatggcCATCATGCGCACATTTCTGATCAAGTAAAGTATGCGATATTGGCACAGCAGCTAAAGGCACGCAAGGATACGGATTTGCTGCAACAGGCGCTGGCCAACGGTTCGAGTAGCGTTGCTGGGAATCCGTTGCTGCATTTTGGCTACAAGCAGCAGACGAGTGGGCTGAGCAACGGGCAGGCTGTGATCagcaatgatgatgatgagcccAAGTTGATAATCGATGAAGAtgatgaggaggaggaggaagaggagccCGAACTGGAGGAGGACGAGGAGGATGAGGAGCTCGAGGAGCTGGATGAGGAGCCAGAAAGGCAGGAGCGCGAAGTAGTGCCACCCACACGCAGCTCCACGCCCATTGAGGCCGCCAAGAAGGTGGCCGAAACCATACTCGAGCAGGCCATCAAGGCGGGTAAACCCCAGGACAGCGACAACATGTCCAAAAAGTCAgcaacagccacgcccacagccaaCACAACCACAGTGACGGCAACacccactgccacgcccacacccacaGCCAACAGCATGAAATCACTGATCGCACAAGCCGAATCCGTAGCCAAATCCCTCAAAGAAGTGGCCAGTTCGCCGTTTAAAGATGAATCTCAGGATCTGGTGCCAGTGTCCAAGCTGGTAGACAATGCCACCAGCAATCAGGTGTCATTCAACAGCTACTTTCGTCCCAGCGACACAGCCAATCACATGGAGCAATCCGATGAGGAGGGTCTGGTGGCCTCCGGCAGTGCCAGCGAGAGCAACAACTCCGGCACCGAGGACtttaccagcagcagcagcagcagcaatgagCCCAAAAAGAAATCTGCCTACAGTTTGGCACCCAATCGTGTCAGCTGTCCCTACTGCCAACGCATGTTTCCCTGGAGCAGCAGCCTAAGGCGTCACATACTCACCCATACGGGACAAAAGCCCTTCAAGTGCTCCCACTGTCCGCTGTTGTTCACCACCAAAAGCAACTGCGATCGTCACTTGTTGCGCAAACATGGAAATGTGGAGAGCGCCATGTCGGTGTATGTGCCCACAGAGGATGTGAGTGAACCGATACCAGTGCCCAAGTCGGTGGAGGAGATAGAGCTGGAGGAGCAGCGACGACGCAAGGCCGAGCAGCTGGAAAGAGAGCGCGAGAGGGAGCGAGAGCGTGAGAGAGAACGTGAAAGGGAGCGGGAGCGTGAGCGGGAACGTGAGCGGGAGCGTGAaaaggagcaacagcaacagcagcagcaacaacagcaactcatGCAACAGCTGGcggctgcggcacaaatagttgctgctgctgcctgcagCACTGCACCCACAAACGCCACCAACTCCTCGCCCATCGCTGCACTGGGCAGTCCAGCCAACAGCGAACTGCAGGCCAATGAGCTGCCCTACAAGTGTCATCTCTGCGAGTACTCCTTCGGTGAGCGTTTGCAATGCTTGGAGCACATCAAGCAGCAACATGCACAAGAGTTTGCACTGCTGCTGGCCAAAGGTGCTATCGAAACGGATGAGCAGCAGCTCACAGCAGCCACGGCCGccacaccagcagcagcagcagcagccaccagcagcagcaacaccaacaccaatgCCATTTCGGATGATGAAAACGGTTTGAACTCACGTACCGTCAAGTATCCCGATTACAGCAATCGTAAGGTGATTTGTGCCTTCTGTGTGCGTCGCTTTTGGTCCACGGAGGATCTGCGTCGTCACATGCGCACCCACTCCGGTGAGCGACCCTTTCAGTGCGAGATTTGCCTGAGGAAGTTCACACTAAAGCACAGCATGTTGCGTCACATGAAGAAGCACAGTGGACGCAGTCACAATGCCTTGGATTTGGCTGGACAATCGGATTGCTCCGATGATGAGCAGTCTGCCACGCCACCCAGCACACCCACACCTACGCCCATGGTCATGCCACaagcccacaacaacaacaacaataacaacaccagcaataacaacaacaacaacaacagttgtcacaacaacaacagcaaacagaatCTGCGTTTGCCCAAACTCCATGAGCTGCTGGACAAGGCCAACGAATGGCGCAGCAGTCGTTTGGGTGAGCACAAGGAGAACATTGCTGAGAGCGCtacgccaacagcagcaacagctgcggccgctgcagcagcagcagcagttgctagCGGTGATCTGATTGGCAATTTGTTGGGCATCAGTGATCAAGGCATACTCAATAAGTTGCTGTCGTCGGCGGATGAGGCAGCCAAGCTGTTGGGGGTGGAGAAGTAA
Protein Sequence
MLATQQQHTTATAATTTGSNSSSAASVVEMERQRRDSSTSESSLEHLDLGRTPKKLSSSNGAPQPTSTPHEITATTATSRKRKLRQQQQQQHLLSDEEEEQKQQQQQQPSELSAQRPRHKQRRNAAASASIVVDYSASGDASSLRKKFRLNRSSAVGSELSESGFVDGSAHSGYLLSSSGSGSGSSSAGSSAQSAAIAAAVVAAQQVAAAAASASASSSSGGSSPNGNLCLSSAESGIGAGEDQMKFLCPICDVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTTQQQQQQTQQQQQQQQQQQQSQSQPQSQQQQSQQQQLSSRRQQQSATAIAVRSESYESDASCSTDVSSAQSHSSNHSSSSNHSNNNNNNNKLSNNNNNTEEQLATLGGNSKRRHKTNINNNNIMEKEELEADEEEEELDNLSDDVAQMITSTPDVATLLASNATTPSPSPAPAAMMLLSCPACNADDFETLPALWQHLDEQHADIPAKCRECEVIFATHRQLQAHACNGMQMLPLLGVSSSPKREELGEEEEEREAEEEEREQDEEEELEEAEREQTKRDDFFQQLYLKGKHSAPAGNNQTLPMLLLSPIKREPSERADNRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDADEEAQDVFTSEFRRMKLRGEFPCKLCIAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEESKALGGQRMGDADLAELSYRSISPPPVEPVSQLKHMLLAEATTTSGAASNSVSTAAVKTAPSKIQVKSLDQLVDKPLAPVLDLSMDVLDLSKKPTATHELQQQQQQEQQQQLQQQRAHERELEREHELLLSQQQQVHQQQQQAQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFGFMPPTAAAEKSAAAALPATAATSSVTPAIAAANLALPLPTGVGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAAASSTAAANAAAAAAAAAAAAAAAAMSNLSQQQHGHHAHISDQVKYAILAQQLKARKDTDLLQQALANGSSSVAGNPLLHFGYKQQTSGLSNGQAVISNDDDEPKLIIDEDDEEEEEEEPELEEDEEDEELEELDEEPERQEREVVPPTRSSTPIEAAKKVAETILEQAIKAGKPQDSDNMSKKSATATPTANTTTVTATPTATPTPTANSMKSLIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDTANHMEQSDEEGLVASGSASESNNSGTEDFTSSSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLEREREREREREREREREREREREREREREKEQQQQQQQQQQLMQQLAAAAQIVAAAACSTAPTNATNSSPIAALGSPANSELQANELPYKCHLCEYSFGERLQCLEHIKQQHAQEFALLLAKGAIETDEQQLTAATAATPAAAAAATSSSNTNTNAISDDENGLNSRTVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNALDLAGQSDCSDDEQSATPPSTPTPTPMVMPQAHNNNNNNNTSNNNNNNNSCHNNNSKQNLRLPKLHELLDKANEWRSSRLGEHKENIAESATPTAATAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00569185;
80% Identity
-