Basic Information

Insect: Drosophila acutilabella
Gene Symbol: -
Assembly: GCA_035046005.1
Location: JAWNOK010000095.1:813281-816437[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6.4e-05 0.005 17.5 5.8 1 23 170 193 170 193 0.97

2 16 0.012 0.92 10.3 2.4 1 23 240 263 240 263 0.97

3 16 0.00064 0.05 14.3 3.3 1 23 323 346 323 346 0.96

4 16 0.003 0.24 12.2 0.4 2 23 398 419 397 419 0.97

5 16 2.7 2.1e+02 2.9 0.9 1 20 532 551 532 553 0.76

6 16 0.02 1.6 9.6 0.6 1 23 562 584 562 584 0.94

7 16 0.00026 0.02 15.5 0.6 1 23 591 614 591 614 0.96

8 16 0.0014 0.11 13.2 1.9 2 23 622 643 621 643 0.96

9 16 0.031 2.4 9.0 0.2 3 19 671 687 670 693 0.93

10 16 0.0021 0.17 12.7 1.3 1 23 730 753 730 753 0.96

11 16 1.9 1.5e+02 3.4 3.0 1 22 760 781 760 781 0.95

12 16 0.0033 0.26 12.1 1.0 1 23 790 813 790 813 0.97

13 16 1.6e-05 0.0013 19.3 0.5 1 23 832 855 832 855 0.97

14 16 0.099 7.7 7.4 0.2 1 23 865 887 865 887 0.94

15 16 1.1e-05 0.00088 19.8 1.7 1 23 893 915 893 915 0.99

16 16 5.3e-05 0.0041 17.7 0.9 1 23 921 943 921 943 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6.4e-05	0.005	17.5	5.8	1	23	170	193	170	193	0.97
2	16	0.012	0.92	10.3	2.4	1	23	240	263	240	263	0.97
3	16	0.00064	0.05	14.3	3.3	1	23	323	346	323	346	0.96
4	16	0.003	0.24	12.2	0.4	2	23	398	419	397	419	0.97
5	16	2.7	2.1e+02	2.9	0.9	1	20	532	551	532	553	0.76
6	16	0.02	1.6	9.6	0.6	1	23	562	584	562	584	0.94
7	16	0.00026	0.02	15.5	0.6	1	23	591	614	591	614	0.96
8	16	0.0014	0.11	13.2	1.9	2	23	622	643	621	643	0.96
9	16	0.031	2.4	9.0	0.2	3	19	671	687	670	693	0.93
10	16	0.0021	0.17	12.7	1.3	1	23	730	753	730	753	0.96
11	16	1.9	1.5e+02	3.4	3.0	1	22	760	781	760	781	0.95
12	16	0.0033	0.26	12.1	1.0	1	23	790	813	790	813	0.97
13	16	1.6e-05	0.0013	19.3	0.5	1	23	832	855	832	855	0.97
14	16	0.099	7.7	7.4	0.2	1	23	865	887	865	887	0.94
15	16	1.1e-05	0.00088	19.8	1.7	1	23	893	915	893	915	0.99
16	16	5.3e-05	0.0041	17.7	0.9	1	23	921	943	921	943	0.98

Sequence Information

Coding Sequence: ATGACAAGGACATGCAGAGTCTGTGGAGAAGCAGACGGACGCTTCTGGATTGAAACACCCGTCAACAAATACGCAGAGAAAACCTTCAATCAACTGCTGTCTGAGTTAACCAGACTTGAGGTCGCTACAGATCAAGCAGACAAGCTGCCACCCTGGCTTTGCCGCAGCTGTGCACAACAGCTGGAAAATGCCTACGATTTTGTGCTGCGAGCGCGTGAAACCCACGAATTGTGGATGCAGAAACTGGCGACGGATGCGGCTCTGGAAGATGCCGAGAAAGGCACCTTGGAGTGCCTGCGAGAGACACCAATACAACTGCTGGAGATCGAGGGAGTTACAATCAAAATGGAGGAGCCCTCGTCGGAACCAGCTCTGCCCCAAGTGGATCCAGCGGTTTCGGTTGATCCGCTAAtcaaaaaaaacttgtatgACACCagcgacgatgacgatgacgacgatgttCCGCTAAAGCAACGCAAGGCACAACATGACAAGCAGTCCATGCTGCACAAGTGCAACAAATGTGACAAATCCTTCAGATACGTGACGAATCTCTTCAGGCACAAGCAGCGAGACCACAGTCCACCCAAGCTCAAATCCAAGGGGGAAAAGTCACACACCGATGGCACTGAATCGTTCTCACACAACCTGCTCAAGAACTCCATGGCAGGCCAGAGCAGCGCCAACTCAGACTTGGACAGTGAAGCTGACAACTACTACAAGTGCGATCAGTGCGAGAAGTCCTACAAGTACATCATGGTGCTCATCAAGCACAAGCACACGGCCCACGGGGTAAACCAGTTGCCAGCGGAGCCCAGGCCAATCCGACGCACTGAATCTGGTGTGGAGCAAGCAACCAAGGTCAGAACAAAGCCACCCAGCACTGATTCCTTAGTGCACAGCATCATCAAAGAGGTCAAAATCCCGGAGGAAGATGAGCTAGACAGCACGGGAGGCGACAACTACTACAAGTGCGATCAGTGTGACAAGTCCTACAAGTATATTGTGAGTCTTATCAAGCACAAGCACAAGGAGCACAACGCGTACAAGGATTCCCACGATTGGGAGGAACAGGAAGAGGCAACTGCCTCCACCTACGCCACGGGAACAAACTCCAAGCCCTCCCGCATCGATCGCCGGGTAAAGGACTTCGATGAGCATCGCTGCAAGCCAAATGGTTCTAAGGAGATTCAGTGCATGATCTGTCTGCGAAGATTCGTTAAGCTGCGGGAGCTACGCGAGCATCTGCGAGCACATCCCCGGGACTTTAAGTTTGATGGCCACGGGGAGCCCATCGAGCGCATTGCCGAGGGATTCTACAGGACCGCCGTGGAGTCCACGGAGACGGGCTTGAAGATACGCATCCTAAACGACCTCAAGCTAGGCATGTTTGGTCGCTACTATTCCATTACCAACGAGGCGCGTTACGAGATGAACCTAGACAGCTCTGATACGGACAGCGATGGCGAGGCAGGAGTCGTGCAGCGACGGAGTTACTCCTGCGAACTGTGTGATTCACCTACAGCCGTTTGGCCACGCAAGTTCCAGTTGCACCAACATCATCGCCAGCACCACACCTGGCTGGAGGCGCCCTATGTCTGTCAGCGCTGTGACTCCCGCTTCCTAAGTGCACAACTGCTCGATCATCACACCAAGAAGCTTTGCCAGAACACTCTGAAACGCTTCATGTGTGACAAGTGCCCGCAGCGATTCTTCTGGCGCCGGAATCTCCGTGCTCATCTCGTGGAGCACAAAAACAAGCAAGAGACTTACCCGTGTGACCAGTGCTCACGCAGTTTCCAGGACAAGAGCGCCGTTACGAAGCACAAACTGATGCTCCACGATGTAGGCAACGAGCTGATCCCCTGTCGATGGTGCACACGCACCTTCTACCGCCTGGCACTGCTCCACAAGCACGTAAAGCGTCATGGCTTCAGTGGCGAGGATCTGCCCTTGGCGGAGACCCTGCTCGCTGATGCGGCCAAGTCTTCCGGACCCAAGACGATTCTTTGCAAACTCTGCGACATGCAGTTCGTGACCATTGCTGATCTGCGCAGGCATAACTCTCTGCAGGCACACAGCGAGGAGAGCAGCAACTACATGATAAGCACCGAGAACGGCTTTGAGCTGCAGCTCGACGAGACGGATGACAGCGATGAGGAGTCTACTGGTGCCACTGGCAGATCTTACAGGTGTGATCTGTGCGACATGACCTTCCAGCGCAGGAGGGACATGAGCGAACATCAGTACTCCCTGCACACTTTCGACTCTCTGCCCCATTCCTGCGAACACTGCATTTTCAAGTCGGTGGACAAGAAAATGCTGGAGCACCATCTGCGCACCCAGTGCCTAAACCAGGAAAAGAAGTTCAAGTGCTCGCGCTGTGGCTACAAGTTCATGTGGAGCGCCAATCTGGACAAACACATGGCCAAGCAGCATGCGAAATCATCGAATCCCACGCCTGCTGTGACCAAACGAAGTCGCCGCTTCAGATACCAGTGTCCACACTGCTGGCGCTCCTTTGTGGTGCAGCCCAGTTTGGACAAGCACATAAGGGACATGCATGTGGCCAAGAAGAATCCCGGCAAGAAGTATCTATGCTCTCTCTGCGGCCTGGAGTCACTCACGCCCAACAAACTGAGCATCCACATGCGACGCCACAACGGCGAGAAGCCCTTTAAGTGCGATCTCTGTGACATGTCCTTCACGGTCTACTACGAGCTGAAAGTCCATCGGAGAAAGCACACGGGTGAGCGACCCTATCAGTGCACCTTCTGTGCCAAGGACTTTGCGCGCCCGGACAAGCTGAGGCGACATGTCTACATGCACAGCGTGAAGCGGTAG
Protein Sequence: MTRTCRVCGEADGRFWIETPVNKYAEKTFNQLLSELTRLEVATDQADKLPPWLCRSCAQQLENAYDFVLRARETHELWMQKLATDAALEDAEKGTLECLRETPIQLLEIEGVTIKMEEPSSEPALPQVDPAVSVDPLIKKNLYDTSDDDDDDDVPLKQRKAQHDKQSMLHKCNKCDKSFRYVTNLFRHKQRDHSPPKLKSKGEKSHTDGTESFSHNLLKNSMAGQSSANSDLDSEADNYYKCDQCEKSYKYIMVLIKHKHTAHGVNQLPAEPRPIRRTESGVEQATKVRTKPPSTDSLVHSIIKEVKIPEEDELDSTGGDNYYKCDQCDKSYKYIVSLIKHKHKEHNAYKDSHDWEEQEEATASTYATGTNSKPSRIDRRVKDFDEHRCKPNGSKEIQCMICLRRFVKLRELREHLRAHPRDFKFDGHGEPIERIAEGFYRTAVESTETGLKIRILNDLKLGMFGRYYSITNEARYEMNLDSSDTDSDGEAGVVQRRSYSCELCDSPTAVWPRKFQLHQHHRQHHTWLEAPYVCQRCDSRFLSAQLLDHHTKKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMLHDVGNELIPCRWCTRTFYRLALLHKHVKRHGFSGEDLPLAETLLADAAKSSGPKTILCKLCDMQFVTIADLRRHNSLQAHSEESSNYMISTENGFELQLDETDDSDEESTGATGRSYRCDLCDMTFQRRRDMSEHQYSLHTFDSLPHSCEHCIFKSVDKKMLEHHLRTQCLNQEKKFKCSRCGYKFMWSANLDKHMAKQHAKSSNPTPAVTKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVYYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00478898;
90% Identity: iTF_00569143;
80% Identity: -