Basic Information

Insect: Drosophila acutilabella
Gene Symbol: -
Assembly: GCA_035046005.1
Location: JAWNOK010000095.1:816762-821365[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00086 0.067 13.9 2.1 1 23 211 233 211 233 0.97

2 25 0.00045 0.035 14.8 1.4 1 23 239 261 239 261 0.98

3 25 0.081 6.3 7.7 0.6 2 23 293 314 292 314 0.96

4 25 0.32 25 5.8 4.0 1 23 391 414 391 414 0.89

5 25 6.2 4.8e+02 1.8 1.4 1 20 455 474 455 476 0.91

6 25 0.0046 0.36 11.6 0.3 2 23 489 510 488 510 0.97

7 25 0.0042 0.33 11.7 0.5 1 23 586 609 586 609 0.96

8 25 0.085 6.6 7.6 0.0 1 22 618 639 618 639 0.95

9 25 1.1 86 4.1 6.3 1 23 648 670 648 671 0.95

10 25 8.6e-05 0.0067 17.1 0.3 2 23 698 719 697 719 0.97

11 25 1.9e-05 0.0015 19.1 5.4 1 23 727 749 727 749 0.99

12 25 0.015 1.1 10.0 1.6 1 23 898 921 898 921 0.95

13 25 0.05 3.9 8.3 2.3 1 22 928 949 928 949 0.95

14 25 0.0088 0.69 10.7 1.0 1 23 958 981 958 981 0.94

15 25 1.6e-05 0.0012 19.4 1.2 1 23 1006 1028 1006 1028 0.97

16 25 0.00014 0.011 16.4 0.9 1 23 1035 1057 1035 1057 0.98

17 25 0.0032 0.25 12.1 0.0 2 20 1084 1102 1083 1104 0.93

18 25 0.013 0.99 10.2 3.9 1 23 1149 1172 1149 1172 0.96

19 25 0.037 2.9 8.8 0.5 2 23 1210 1232 1209 1232 0.94

20 25 0.00099 0.077 13.7 3.5 1 23 1257 1280 1257 1280 0.97

21 25 1.4e-05 0.0011 19.5 0.1 2 23 1309 1330 1308 1330 0.95

22 25 4.7e-05 0.0037 17.9 2.9 1 23 1336 1358 1336 1358 0.99

23 25 2.3e-06 0.00018 22.0 2.0 1 23 1364 1386 1364 1386 0.97

24 25 5.9e-08 4.6e-06 27.0 2.4 1 23 1392 1414 1392 1414 0.99

25 25 0.00074 0.058 14.1 0.3 1 22 1420 1441 1420 1444 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00086	0.067	13.9	2.1	1	23	211	233	211	233	0.97
2	25	0.00045	0.035	14.8	1.4	1	23	239	261	239	261	0.98
3	25	0.081	6.3	7.7	0.6	2	23	293	314	292	314	0.96
4	25	0.32	25	5.8	4.0	1	23	391	414	391	414	0.89
5	25	6.2	4.8e+02	1.8	1.4	1	20	455	474	455	476	0.91
6	25	0.0046	0.36	11.6	0.3	2	23	489	510	488	510	0.97
7	25	0.0042	0.33	11.7	0.5	1	23	586	609	586	609	0.96
8	25	0.085	6.6	7.6	0.0	1	22	618	639	618	639	0.95
9	25	1.1	86	4.1	6.3	1	23	648	670	648	671	0.95
10	25	8.6e-05	0.0067	17.1	0.3	2	23	698	719	697	719	0.97
11	25	1.9e-05	0.0015	19.1	5.4	1	23	727	749	727	749	0.99
12	25	0.015	1.1	10.0	1.6	1	23	898	921	898	921	0.95
13	25	0.05	3.9	8.3	2.3	1	22	928	949	928	949	0.95
14	25	0.0088	0.69	10.7	1.0	1	23	958	981	958	981	0.94
15	25	1.6e-05	0.0012	19.4	1.2	1	23	1006	1028	1006	1028	0.97
16	25	0.00014	0.011	16.4	0.9	1	23	1035	1057	1035	1057	0.98
17	25	0.0032	0.25	12.1	0.0	2	20	1084	1102	1083	1104	0.93
18	25	0.013	0.99	10.2	3.9	1	23	1149	1172	1149	1172	0.96
19	25	0.037	2.9	8.8	0.5	2	23	1210	1232	1209	1232	0.94
20	25	0.00099	0.077	13.7	3.5	1	23	1257	1280	1257	1280	0.97
21	25	1.4e-05	0.0011	19.5	0.1	2	23	1309	1330	1308	1330	0.95
22	25	4.7e-05	0.0037	17.9	2.9	1	23	1336	1358	1336	1358	0.99
23	25	2.3e-06	0.00018	22.0	2.0	1	23	1364	1386	1364	1386	0.97
24	25	5.9e-08	4.6e-06	27.0	2.4	1	23	1392	1414	1392	1414	0.99
25	25	0.00074	0.058	14.1	0.3	1	22	1420	1441	1420	1444	0.91

Sequence Information

Coding Sequence: ATGTTGCCGCACGACATATGTCGTACTTGTGCGCTGCACAATGCAGACTTGTTTGCGCTCTCAACGCTCACCGagaaatatgcaaacaaaAGTTATTGTGACATGTTGCATGAGTTAACACAAAACGATCCCTTGATGGAAAACTTGCCTGAGAATTTACCACAGCACTTGTGCGGCGAGTGCCTGTGTAAGCTGGAAAGCGCCTATGCCTTTGTGCTGCAAGCACGTCAGGTGCAGGAGCAACTGTTGCACAAAATAAGCAAGGGACTGGACTGTCTAAAGGAAACGCCCATTGACATATCCACGCAGCATATCAAGACGGAAACAGACATTACTTTGGCGGTGCCGACAGACGACGCCGAAGATGACAACGCCGCTATGTCGATAGCAACTCTAAAGGTACAACCAGAGAGCGACACCGACAGCAGTCAAGCAGCAGAAGATGAAGCCGACAATGATGTGCTAGATCTTAAGCCTCTGCAGTTAAGACGCAGCTGCCGCAGGCCAAAACTTTCCACAGACAGCGAAAATGAAGCGGCCATTGAAAACCCGAGTGCAGTGCCGCCAAAGCGACGTCGGGGACGCCCAGCGCGTCTACCCCGTAAGGAAACCGTAAATAAGGAAGGACGACATGTGTGCGAGGTGTGTGGCAAGACCTTCTCATGGCATCGGGACATGCAACGTCACGCACGCGTGCACTTCGAGCAGGCTGGCTATGTGTGTGACAGCTGTGGCAAGGAATTCATCCGCAAGGATAAGTACATGTTCCATATGAGATCCCACGAGAAGCGTCAAGCCAAACAGCAGGCTCTGCAACTAAGCCAAGAGTGGCGCTTCGCTGAGCGTCTCTACAGCTCCGGAAGTCTCAAGCGCATCGAGTGCAAGCTCTGCGGCCTGAAGTGTGAAAAGATTCAGGAGCTGCGCGATCATCTCTCCATACATGCCAACATAGAAACCCTATCAAATCTCAGCCACCATAATGATGTGGTTTTGGAGCACTTTGCCAACGACGCCAGTCCATTGGACTTGCTGGGTATAAGGCAGCAGGTGAGCGCGGACATAGGCCAGGGACGAGCTTGCCTAGATAAGTACTGCTCTGTAGTGAATGCCCTTGGTTACGAGCTGTGTCTCAGTGACTCGGATGAGGAATGCGCAGAAGAGACGCCTCCATATCATTGCCTGCCTTGTAACACTAGCTTTTCCAGGAAGCATCGACTGATGAGCCACACGCTGGAGGAGCACACTCAGCCTACCAGTCAGACGTTTCCCGGCCAGCGTTGTAGTCACTGCCAGATTGGCTTTGTTTGCGCCAAGCTCATGGAGCAGCATCAGCGCACACAGTGCCACAATCCTTTAAAACGCTTCACTTGCTTCAACTGTCCAGGAAAATTTATGTGGCCAGAGAATCTGAGGCATCATGCGTGCTCCAGATCAGCAGAGGACGTGGATCAACGACGAAAGATTCAGTGTTGTCTCTGCGGTGAGCAGCTCCCAAGAATGTCCGCTTTACGCGCTCATCTGCTCACCCACGATGATGGAACCAGTGGCATCAGCTGGGACCAAGCTACTAGCTTCATTCGTGATCAGTGCCCCGATGCTGTCAGCTGGGATCAGAACGAGATCAGCAGACGGATTGTCAGTGACTTTGAAGCACAGGATTATGGAAGGTATTTCAATGCCTGCACAGGCAGTGGTCAGGAGTTAGATTTCTTGGATTCCGACACGGATTTAAGCGACCCCTCAGCTCCATCTGTGCACTCCTGTGAATTGTGCGGTATGAGGACTCCACGCCTAGCTCAGCTCTTGGAACATCAGCAGAAGCTTCACTCAGAGCAGCTTGATACACTGCCTCATGTGTGCGTCACGTGTGGACTGGGATTTGTAGCGGAGGCGCTGCTGCAACAGCATCGACGCCGCTGCTGCGCCAAGCGACATGCCAAGTACCAGTGTGAGCACTGTAATCTTCGCTTTATCTGGAAGTCCAACCACGAGCGGCACGTGAAACTACACCACGAGCAGGAGACAGGAGCTACACCCGAGGACTTGCCCAACACAAGGCTAAGAAGCAAACGCCAAGAAGCTGCCAAACTGCAGTGCAGTGAATGCGATAAGGTCTTTATCTGGCCCAAGGATCTGACGCGACACAAGCGCATCCATCAGCCGCAGGCATCGGCACAGTACGAGTGCAGTCACTGCGAGCGCAAGTTCCACCGGAAGGATGGACTCAAGTCGCACATGCGCGTCCACGGGGAGCTGCCATTGGAGACTGCTGGAAGCATGGCTAACAGCGAACCGGATCTGTCTGTATGGCCATTGGTGTGGACACAGTTGTGCCAACCGAATGGCTGCAAGCAGATCCAGTGTATGATTTGTCTCTCTCGGCACTCAAAGATCGCTGATCTTCGCACGCATCTCCTGAAGCATCAGTTTGTAGTGGACTTCGTTGAGGAGCGTGCCCAGCCGGCGGGCATTGCTACCATTTGTCGTGCTCTCTATCCGGAGCTGGTGACCACGTTGGACAGGCAGCAATTGATTGAGCGCATTCAAAGAGATGTGAGCGAGGGTATTGAGTTGGGTAGATTCGTTTCCATCACCAATGAGGCGAGCCTTGAACTCAGCCTGGACAGCAGTGAAACCGATACGGATTCGGACACAGCCTTAAGCTTAGACGATGTGGTTGCCAACTCCCAGTACAGCTGTAATCTTTGCCAGCTGAAGCTGCCGCGGAAACATCAGCTCTATGCCCACCAGCTAGAGCAGCACACTTGGCAACAGGCAACGCACATCTGTACACATTGCCAAGCCAGATTTATCAGTGATCAGTTGCTGGAGCATCATTATAGAACACTCTGTCGCAATTCCCACAAGCGTTTCCTCTGCCGGAAATGCCCATTCCGCTTCCGCTGGCGGGACAATCTTAAACTGCACATGGATACAGCTCACCAGGAGGTAACGGGGGAGCAGACGAGCTTGGCACTCCAGCTGAATGGATCAAGTCTGTTGCCAGTGGTCAGCTACGACTGCGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTTACAAGGCACACTCTGATGCACGCTAAGGATTCGAGCATTTATCGGTGTCGCTGGTGTGCTCGACGCTTCTATCGTCAGGCAAATCTTCTGCAGCACATCGAGCGGCACGGCATCCATGCCTCCCAGCTACCCTATGCTGAGACCCTGCTCAACGCCAGCCGGCACCCTAATGGCCAAAAGTGCATCCAGTGCAAGGTCTGCGACTTAAACTTTCCCACAATCTCTGCACTGCGCGCCCACTTGACCTCCACTCCTCAGGGGACTCATCATGCCATGGATTCAATGTTAAACTACTCGATCACCAATCAACAGGGCTACGAGCTCCATCTAGACGACTCTGAAACAGACGTCGAGGTAAAGTCACCCGGCACACCCACGCACTACACCTGCGGCATGTGCCAGCTCAGGTGCGTGCGGAAGTATGAGCTGCACCAGCATCAACAAGCCATGCATCGTCTGGAACGCATCACCGAGGGCTGTAATCAGTGCATTTTTAAAAGCGTTTGCCCCAATCTCATTGCTCATCACCATCGGACGCAGTGCGGCAACACGGAGAAGCAGCTCAAGTGCGTCCACTGTGGCTACAAGTTCATGTGGGAGGCGAATCTTCAGCTGCACATACAGCTGCAGCACTCCAGCCAAGATGGCCACGAGGTGGGTTCAACTGCCCCACTTCCAGATGACTCAGCCACAGAGTGCCACATCTTTCAGTGTGGTCAGTGTCCACGCAAGTATAATCGTAAGGATAGGCTGACGGCACATGTTAAGAAATGTCATGCCTCAGGAGCAGTTGGTTCTGCTCTCCAGAGTCCAACGAAGACAACGACGCCTCCAACTGTGGCCAAGCAGCAGAAGAGCTTCCTCTGCGCCTTCTGTGGCAAGGCGGTGAGCTCCTCCTCCAATCTGATCATTCACATACGTCGGCACACAGGAGAGAAGCCTTTCAAGTGCGACTACTGCGACATGGCATTTCCACGCTCCTCTGATCTGCAGTGCCATCGACGCACCCACACGGGCGAGCGTCCTCATGTGTGCACTGTGTGCCAGAAGGGATTCGCCCGCTCCTAcaagctgcagcagcacaTGCGCATCCACAACGGAGAACGGCCCTACAAGTGCACCTACTGCGACAAGAGCTTCACCCAGTCCAATGATCTGACCCTCCACATACGAAGACACACCGGGGAGAGACCATATCAGTGCGACACCTGCGGGGAGCGTTTTATACAGGGAACCGCGCTCAAGAATCACCGTCAACAGAATGGACATTTCGAAGCTAGCGGGGGACTGGCtgcagataaataa
Protein Sequence: MLPHDICRTCALHNADLFALSTLTEKYANKSYCDMLHELTQNDPLMENLPENLPQHLCGECLCKLESAYAFVLQARQVQEQLLHKISKGLDCLKETPIDISTQHIKTETDITLAVPTDDAEDDNAAMSIATLKVQPESDTDSSQAAEDEADNDVLDLKPLQLRRSCRRPKLSTDSENEAAIENPSAVPPKRRRGRPARLPRKETVNKEGRHVCEVCGKTFSWHRDMQRHARVHFEQAGYVCDSCGKEFIRKDKYMFHMRSHEKRQAKQQALQLSQEWRFAERLYSSGSLKRIECKLCGLKCEKIQELRDHLSIHANIETLSNLSHHNDVVLEHFANDASPLDLLGIRQQVSADIGQGRACLDKYCSVVNALGYELCLSDSDEECAEETPPYHCLPCNTSFSRKHRLMSHTLEEHTQPTSQTFPGQRCSHCQIGFVCAKLMEQHQRTQCHNPLKRFTCFNCPGKFMWPENLRHHACSRSAEDVDQRRKIQCCLCGEQLPRMSALRAHLLTHDDGTSGISWDQATSFIRDQCPDAVSWDQNEISRRIVSDFEAQDYGRYFNACTGSGQELDFLDSDTDLSDPSAPSVHSCELCGMRTPRLAQLLEHQQKLHSEQLDTLPHVCVTCGLGFVAEALLQQHRRRCCAKRHAKYQCEHCNLRFIWKSNHERHVKLHHEQETGATPEDLPNTRLRSKRQEAAKLQCSECDKVFIWPKDLTRHKRIHQPQASAQYECSHCERKFHRKDGLKSHMRVHGELPLETAGSMANSEPDLSVWPLVWTQLCQPNGCKQIQCMICLSRHSKIADLRTHLLKHQFVVDFVEERAQPAGIATICRALYPELVTTLDRQQLIERIQRDVSEGIELGRFVSITNEASLELSLDSSETDTDSDTALSLDDVVANSQYSCNLCQLKLPRKHQLYAHQLEQHTWQQATHICTHCQARFISDQLLEHHYRTLCRNSHKRFLCRKCPFRFRWRDNLKLHMDTAHQEVTGEQTSLALQLNGSSLLPVVSYDCGECNRSFKMQKDLTRHTLMHAKDSSIYRCRWCARRFYRQANLLQHIERHGIHASQLPYAETLLNASRHPNGQKCIQCKVCDLNFPTISALRAHLTSTPQGTHHAMDSMLNYSITNQQGYELHLDDSETDVEVKSPGTPTHYTCGMCQLRCVRKYELHQHQQAMHRLERITEGCNQCIFKSVCPNLIAHHHRTQCGNTEKQLKCVHCGYKFMWEANLQLHIQLQHSSQDGHEVGSTAPLPDDSATECHIFQCGQCPRKYNRKDRLTAHVKKCHASGAVGSALQSPTKTTTPPTVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRQQNGHFEASGGLAADK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00569115;
90% Identity: iTF_00478873;
80% Identity: -