Basic Information

Insect: Drosophila acutilabella
Gene Symbol: Btbd7
Assembly: GCA_035046005.1
Location: JAWNOK010000020.1:33178123-33181254[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.5e-14 4.3e-12 46.4 0.0 10 102 150 244 142 251 0.85

2 3 2.7e-05 0.0078 16.6 0.0 22 45 286 310 282 357 0.68

3 3 4.3 1.2e+03 -0.1 0.0 75 106 379 411 375 413 0.83

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.5e-14	4.3e-12	46.4	10	102	150	244	142	251	0.85
2	3	2.7e-05	0.0078	16.6	22	45	286	310	282	357	0.68
3	3	4.3	1.2e+03	-0.1	75	106	379	411	375	413	0.83

Sequence Information

Coding Sequence: ATGGGGGCAAACACCTCTAGTAGTGGTTATCCTATAACCACACCTGCTCAAAACACGAGTGGACTTGGCACCGCAGACATGTCTATACATCATGCTACCACTACAAGTATAGGATCATCAGGATCTAATGAAAGCGGAGTAGTCCCTGCTTCGAGTGGATCCTACAGTGGCGTACATTACCATCGGGACCAAAGGCGAAAACGAGTTACTGGGTTTGCAACTCTAAAAAGGAAGTTTATTCGTCGGCGACGTTCATCGAAAGCATGCGACCATGCGCGTGTTCTCCGTGATTTTGTCTGTGACTGGACGCCTCTTGAATTGGCTGCACTTTGTGAGGAGTTTGAAGCTTTGGCAGCTTTAAAAGATTTATCGatgcAGGCCGAATTGGCGCGACCTCCGGCAACTACATTCAAACAAGATCTGGCTGCTCTTTATGATTTACGTTTGTGTACAGATTGTGACCTTGTGTTTCGTGGATCTATTTTTCCAGTGCATCGCTCTATTTTATCTTCTCGTTGTACATATTTTAGAGATTTGCTTTCTGGATGTCCTGGATTTGGAGCTCGCATTTGTCTCGAACTTCCTTCATCGCCAATtgatgtgcaaatatttgcctcATTGTTGCGATATCTTTATACAGGCGATCTTTGTCCACATGATCCTACCATCAATATTAACCTACTTCGTCAACTAGGGGATGATTTTGGAACACCTAATCCTCTTGAGCAAGATCTACGTTATTTGTTAGAAACCGGGGATTATGCTGATGCTGCTCTAGTATTTACAGCAGACGGTACAAATGACTGCTTACGTCAGGACTCGGGTAGTTCAGAGTACGGGTTCAGACCAAAGCTTGAGCTTCCATGTCATAAATCTATATTGAGTGCGCGTTCACCTTTTTTTCGTAATCTCATTGCCCGCCGAGCTCGAAACCTTGATGAGTATATAGAGCGGTCTATCCATGTACCCACTCGTATTGTTCTGGACGAATCCGTCATACCGAAGAGATATGCACGAGTTCTACTACAAGCTATATACTTAGACACGGTTGATTTGACACTTATATTGCGAGGAGCTGGAACCGGAAACTCTACTGGTTCACTTGGAGAGGTTCATGCATTAACAAACACTGGTCGTGTACGACCAACGACTCTCGAAGAAGCAATGGAATTATACCAAATCGGACGGTTTCTTGAGCTTGATATATTAGCGCAAGGCTGTGAAGACTTGATCCTAGAGTGGTTGTCAATTGACACATTATCAATGGTTTTAAAGTGGGGTTGTCAGCCCTACGGCTCTGCATGGGTTTTTAGGCAAGCGTGCCAATACTTACGTGAAGAATTTGCAACAGTCAGCACGTCACCTGTACTTTATCAGTTGGATAAGGAACAACTTTTACATATATTACAAAGCAATTTTTTGCAAGCATCAGAGCTAGAAGTATTACAGGCGGTTCTTAAATGGGGTGAGCAAGAGCTTATTCGGAGAATGGAAGATCGAGAACCAAATCTACTATCGCACACTGCGCATTCAGTGACAAGAAAAGGCGTCAAACGACGCGATCTAAGTGACATTGAGCTGCGCGAAATACTTTCCGAGCTACTGCCTTTGGTGAGGATGGACCATGTATTACCGCCAAATAGTGAAGTATTATGTCAAGCTATACGTCGTGGCCTTGTGAGTACTCCGCCCTCGCAAATGATAGGAGAGGAACGTGAACATTTACGTGTTAATGCTTGGATACGTGGAGGAAAAAATCAAGATCTCTTTGTACGCCCACGGCTCTTTATGCCGTATTTTGAGGAAGTAAAGGCATTACTTGAAGATCGTATGGCATCATCTCATCACCAAGTGGAACTCATGCGAATGCGTAGGTCACGGCACTTTCCAGATATCCCAGACACTCTTTACATGGTATCGCGTATGAATGCCGTTTCAAATAGAGATTTTGCTTCTGACGCTTCTTGCAGATTTGGTGGtaacagtttaaataaatctacaGTCATACCATCACCTGATAGTCACACAATATCAGCAATGAGAAAGCGTGAACATAAACTTCGACAGTCACCAATATGTCAAAGAGCAATGCTTCTTCCACTTTCATCAAAGCATGATATTATACAACAAATTCGCCTTCGAGTCGTAAGAGAGTTTAACTTTCCAGATGAAGTGTCTGATTTACTTGGAAATTTTCATATGACAAATCAAACTGATAGCAACAGTAAGAAAGAATGCGAAGGCGATCGTTCGATTACACATGAGGAGCAATGTTTGTTAGAGGATGAAGGCCGAAGCTCGCCTCCTTCACCAGCAACGACATCCGAAACAACTGTTGTATCGTCATTTTTGTCAACAACGCCAATGACTTCATCAACATCTTCTGTTTGTGGCTCTCGTGCAATGCAACCATGCTATAGTCGAAATTTAACCTATCCTCGGCATCAAACAAGCGGCCTACTAGGTGTTGAAACCCTTTTGGCATCTAACTCGGGTACACCACAACAGACAAATTTTACTCGTTTTTCTTCTTCAGCTCATCAACGACATGAACTGCCTGCTTTGATTACTGAAGGCGATTTTCGATTTCCACATGGTAATGTTTTGAACATAGACGGTGTATTTGAGGGCGGGTCTAGTGGATTAGAAACTGGAAATGGGCATCTTTCTGACATGATGCCCGATGTGGCAATGGCTACAGCATCCTTGGGTCAGCTACATCTGACCAATGGTTCTGGTTGTGTCACTAGTGTCGGTAATCGCATAATTAGCAGTAGCAGTGATATGTCTGAAAGTTTGGACCTAGACTTAGGGGATGGCCCCAATCCTCACATAATCAATAGTGCAGCCGGTGTAATGACATTGCGCAGCTTACAGCATCAATTGCCGCACAGAAATTATAACCACCTCATGCAGCGTTCGAGTTCACCATTTGATATTCTGCGACAGGGGCAGGACTCTCCTGTTCCTCAACATCCCCCTTCAGGTGCATTAAACTCTACGCCACCTAGATTTTTATAA
Protein Sequence: MGANTSSSGYPITTPAQNTSGLGTADMSIHHATTTSIGSSGSNESGVVPASSGSYSGVHYHRDQRRKRVTGFATLKRKFIRRRRSSKACDHARVLRDFVCDWTPLELAALCEEFEALAALKDLSMQAELARPPATTFKQDLAALYDLRLCTDCDLVFRGSIFPVHRSILSSRCTYFRDLLSGCPGFGARICLELPSSPIDVQIFASLLRYLYTGDLCPHDPTININLLRQLGDDFGTPNPLEQDLRYLLETGDYADAALVFTADGTNDCLRQDSGSSEYGFRPKLELPCHKSILSARSPFFRNLIARRARNLDEYIERSIHVPTRIVLDESVIPKRYARVLLQAIYLDTVDLTLILRGAGTGNSTGSLGEVHALTNTGRVRPTTLEEAMELYQIGRFLELDILAQGCEDLILEWLSIDTLSMVLKWGCQPYGSAWVFRQACQYLREEFATVSTSPVLYQLDKEQLLHILQSNFLQASELEVLQAVLKWGEQELIRRMEDREPNLLSHTAHSVTRKGVKRRDLSDIELREILSELLPLVRMDHVLPPNSEVLCQAIRRGLVSTPPSQMIGEEREHLRVNAWIRGGKNQDLFVRPRLFMPYFEEVKALLEDRMASSHHQVELMRMRRSRHFPDIPDTLYMVSRMNAVSNRDFASDASCRFGGNSLNKSTVIPSPDSHTISAMRKREHKLRQSPICQRAMLLPLSSKHDIIQQIRLRVVREFNFPDEVSDLLGNFHMTNQTDSNSKKECEGDRSITHEEQCLLEDEGRSSPPSPATTSETTVVSSFLSTTPMTSSTSSVCGSRAMQPCYSRNLTYPRHQTSGLLGVETLLASNSGTPQQTNFTRFSSSAHQRHELPALITEGDFRFPHGNVLNIDGVFEGGSSGLETGNGHLSDMMPDVAMATASLGQLHLTNGSGCVTSVGNRIISSSSDMSESLDLDLGDGPNPHIINSAAGVMTLRSLQHQLPHRNYNHLMQRSSSPFDILRQGQDSPVPQHPPSGALNSTPPRFL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00587493;
90% Identity: -
80% Identity: -