Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0008 2.5 10.2 0.5 21 48 117 143 110 146 0.88

2 7 0.00059 1.8 10.6 0.1 21 46 145 170 143 174 0.91

3 7 0.001 3.1 9.9 0.0 21 47 181 207 171 212 0.85

4 7 0.051 1.6e+02 4.4 0.1 21 45 209 233 206 239 0.86

5 7 0.049 1.5e+02 4.5 0.0 22 47 238 262 235 265 0.86

6 7 0.00075 2.3 10.3 0.1 21 49 265 292 262 297 0.82

7 7 0.83 2.6e+03 0.6 0.9 22 43 294 315 291 323 0.67

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0008	2.5	10.2	0.5	21	48	117	143	110	146	0.88
2	7	0.00059	1.8	10.6	0.1	21	46	145	170	143	174	0.91
3	7	0.001	3.1	9.9	0.0	21	47	181	207	171	212	0.85
4	7	0.051	1.6e+02	4.4	0.1	21	45	209	233	206	239	0.86
5	7	0.049	1.5e+02	4.5	0.0	22	47	238	262	235	265	0.86
6	7	0.00075	2.3	10.3	0.1	21	49	265	292	262	297	0.82
7	7	0.83	2.6e+03	0.6	0.9	22	43	294	315	291	323	0.67

Coding Sequence: ATGGATGATTCTGATGTAAAGAGCGAAATTGGTGAGCCAGATATTCCTGGAAAAAAGAAGCAAGAAACTGAAAAAGTCCTGATCAAAGAAGAATTAAATATATCCGAAAATGATGTTGAAGATACAGAACAAGCAGATAATTCTTGTTCAAAAACAGAAAGTGAAGAAGAATATAGCGAAGATGATATAAGTTTGCAAGAAAACGATCCGCTAGAAAATTTCTTGGAAGTAATGATAGTCGAAGGAAAACAAGATGAACATTCTGGAGTGATACCACTCAAATGTCCTTTCTGTCCGAAAACATTCAACGGCTTGCAACCTTTGAATTGTCACAAACGCATCCACGGGAGTAAAGAACCACGTACTTgtaatatttgtcaaaaaacattCGCACGAGGCTGTGATTTACGGAGACATGAACTTATTCACAGCGGAGAAAAACCACATGTATGCGATGTCTGTCAGAAATCTTTTGCACAGAGCAGTAGTTTAAAAAGACACAAACAACTTCACACTGGTGAGGTTAAACGTGTTCACAATTTAGAAAAACCATATGTTTGTAATATCTGTTTAAAAACATTCGTTCGGAGCAGTGATCTAAcaagacatttatttattcacagcGGCGAGAAGCCGTACGAATGTAATGAATGTCAGAAAAAATTCTATCGGAGTAGTAATTTAAACAGACACAAGTTACTTCACCTTGGTGAAAAAACATATACGTGTAGTTACTGCAATAAAGCATTTGCAGAGAGCGGCAATTTGAAGAAACATGAACTTATACACAGCGGTGAAAAACCATTTGCGTGTGATATTTGTCCTAAATCATTTGTACAAAGTAGTCATTTAAAGAGACACAAACTTATTCACAGCGCGCGGAAACCATTCTCCTGTGATATATGTCACGAAGCATTCGCTCGGAGATGTCATTTAAAGAATCATAGACGTATTCACATTGTTTTGAAAAGATAG
Protein Sequence: MDDSDVKSEIGEPDIPGKKKQETEKVLIKEELNISENDVEDTEQADNSCSKTESEEEYSEDDISLQENDPLENFLEVMIVEGKQDEHSGVIPLKCPFCPKTFNGLQPLNCHKRIHGSKEPRTCNICQKTFARGCDLRRHELIHSGEKPHVCDVCQKSFAQSSSLKRHKQLHTGEVKRVHNLEKPYVCNICLKTFVRSSDLTRHLFIHSGEKPYECNECQKKFYRSSNLNRHKLLHLGEKTYTCSYCNKAFAESGNLKKHELIHSGEKPFACDICPKSFVQSSHLKRHKLIHSARKPFSCDICHEAFARRCHLKNHRRIHIVLKR

Sequence clustering based on sequence similarity using MMseqs2