Basic Information

Gene Symbol
-
Assembly
GCA_948098885.1
Location
OX402535.1:13778867-13783267[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.0063 0.51 10.7 0.3 2 23 197 219 196 219 0.93
2 22 0.00087 0.07 13.4 0.2 1 23 250 273 250 273 0.95
3 22 0.08 6.4 7.3 0.8 2 23 280 302 279 302 0.96
4 22 7.9 6.3e+02 1.0 1.8 1 23 316 338 316 338 0.93
5 22 4e-05 0.0032 17.6 0.6 2 23 374 396 373 396 0.95
6 22 0.27 21 5.6 0.7 2 23 424 446 424 446 0.94
7 22 0.17 14 6.2 0.6 3 23 454 476 452 476 0.93
8 22 0.76 61 4.2 0.1 2 23 485 507 485 507 0.93
9 22 3.3e-05 0.0027 17.9 0.3 2 23 547 568 546 568 0.96
10 22 0.012 1 9.8 3.2 1 23 614 637 614 637 0.95
11 22 0.0016 0.13 12.6 1.6 2 23 644 666 643 666 0.96
12 22 0.0061 0.49 10.8 1.6 1 21 689 709 689 710 0.91
13 22 1e-05 0.00081 19.5 4.5 1 23 725 748 725 748 0.97
14 22 1.4 1.1e+02 3.4 0.3 7 23 762 779 752 779 0.83
15 22 7.3 5.9e+02 1.1 3.8 3 23 787 809 785 809 0.91
16 22 0.21 16 6.0 3.9 1 23 816 839 816 839 0.96
17 22 0.1 8.3 6.9 0.1 3 23 878 899 877 899 0.86
18 22 1.7e-05 0.0014 18.8 0.2 2 23 905 926 904 926 0.96
19 22 0.0053 0.42 11.0 3.1 1 23 992 1015 992 1015 0.95
20 22 9.6 7.7e+02 0.7 0.9 1 23 1076 1098 1076 1099 0.81
21 22 0.05 4 7.9 1.0 1 23 1108 1130 1108 1130 0.96
22 22 0.025 2 8.8 1.2 1 23 1140 1162 1140 1162 0.96

Sequence Information

Coding Sequence
ATGTCGCGATTACATCATATTCAACCAGAAGTATCAATTTTTGCGGTTTCTCCTAATCCTCCATCTAAACCGAGAAAAATTAAGAGTCAACCTCCAGCTCTTAAACCAGCAATATGGCCCACCACCAAGCCACCTGTTGCATCTATGCATCTACAACAATTTTTGAAAGCTCATCGTTTAAGTCAAAAGCCACCGGTACAAAGAGAGCCTCCACCATTAAATAAAATGCAATATTTTGCTAATGATAGTCGTACAGAGTATCAAAAACAACAGCAGCAGATGCATCAAAAACTTGTGCAACAACGAATGGCTAACAATAATAGTATACGAGAAGATTCACCAAATCCAATGGATTTTCTTGAGATTGGTGTTCATGCTGGAAACAGTATCATTAACAATATTCCTAAAGAAGTAAAATCAAAAACTAATTTAAAATCGGGAGGAAGTAGTATTATATCACAAACGGATACTAGTAGCCGTCGGAAAAATGCTAATCCAAGAAAAGTGGCTCGAGAAAATGAAATCGAACCCCCAGGACCAAGTAATCATTTTCTATTGTCTCAAACTAAACCAGATAACCTCCGTCAATCCTGTTTACTGTGTGAACGAAATTTCGGCAATAAATATGATCTTAGCCAACATATATCTGAAGTGCATGGTATCGAACCATCTGATCTACATCAATTAAATGGAAATTTAGCTGATGATGATGAATTCGTTGAAAGTATGATGGAAGCTGAAACCGTATTCTTCTGTGAAGTATGTACTAGAGAATTTCAAGACAAAGCTAGTCTTTGGCTGCACATGGTTCGAGGTCATAAACAGGAAGCTGCGGTAACATGTGGCGTATGCATGAAAATTTGCAACGACAGTAAATCTCTTATGGAACATGTTAATACTCAACATCCTAAAAGTAGCGATACAGCTGATTCCATTCAACGTAGGTATAGGTGTCAGGTGTGTGCTCGGCAACATGATACTAAGAAAAAGATGATGAGGCATGTTGTCATTCATACAGTGTACGATAATGATGGCCAAATAATAGATCCTGATAAATTAATTATAATCAATAATAATTTTCATCCCACCAAAGCTTCAAATAATGAACACTATACGATTAGTTGTCAAGTGTGTCACAAAGTGTTTCCGAGTGAAGAAAAACTTTTACGGCATATGTCTTCGGTTCATTTGATGACTGTTTGTGATGATATGATAACTACGACGACTGTAACAACTACTGGAAATTCGTCTCAGAGCAGTTTTGTGAATCGTTGTGAATTATGTGGCGAATCGTGTGGTTCTCGTACTGAAAAATGGTGGCATGTGCTCAAAGAGCATGGCACTAATGAAGCTCTCATATGTCCGAAACCAGACTGTAGAAAGCTATTTGTGTCGCAATCTCTACAAATTGAACATCAATCTCATCACGAAGCTCAAGGCGATCTCCCCAATACCTGTGAAGTGTGTGGCCGGTTATGGCCCAATCGAAATGACTTTTACAAACACATTATGGCCGTGCACGCTGAATGTATGCCTTTGTTATGTGGTATATGTTTGAAAGTTCATATTGATGTACCGAAACTCAGAGAACATATAAAAGAAAAACATGAGCCTTTGGTTTCAAAAGAAAATGCGATTTACTGCGATATATGTGGACGAACTTACACAAAATGGTCGAAAATGATGAGGCACAGGGCAATACACAATGTAGAAGACCAAGTGTCTCATTTTGTAACAGATCAATTGACAGAAGTGAACCTTAAGTGCACACTGTGTCCCGATACCGAATTTAAAACTGTTGAAGAGATTTCTGAACACAGAAAAAATGACCATCAATTGCATGTGTGTGACTTATGTTCAAAATACTATAGTGGTAATAATCATTTATGGAAACATGTAAGCAGGCAACACAAAGGTCATCCGGACGTTACATGCAGTTTATGTGCTCGTACGTCAGCATCTAAAGTTCATCTCAAAAGACACATGATAAAATATCATTCTGATCCGGTAGATCAGCTTATAGATAAGTCAAATAATAGTAGCTGTGCAGAAATAAATTCCATTCATCAATGTATTAGGTGTGACAAAGTATTTAGGATTAGGAGTTTATTGAAAAAACATCTCAAGTATTGCAAGGGCAAAAAAGATGCGATGGCCAAAGAAAAGGGTCACTTTCCTTGTCCAAAATGTCCTAAAACATTTGATTATCACACTCATTTAAACAGACATTTAAGGCAAAGTCATTTAGTTCAGTACTGTGAGTTATGTTCAGAGGATAAAAGTGGTGAACATTTCGATAACAAAATGTTACTAATGGATCATATCAGAGAAAAGCACAGCAAAGATCCAGAGTTGTGTTGCGACGTTGAGGGCTGTGATAAAGTCATGAGAACAAAAACTGATTGCCAGAAACACAAACGAGATCATATTCGCAAAGTGTTTTCGTACGTGTGTGAATTTTGTGGCGATATGCACTCTAATAAGAAAAACTATAGAAAACATTTGCGGCAACGGCACAAAGGCAATACTCAGTATTTATGTGGTGTGTGTATGGAATTATGTGTTGATGTCGATGGTTTATCAAAACATCTGCACGAAGCACACCCGCAGACATTTACCAAATCTAACATTTGTCAAATCTGTGGGAAAATATTTACTGTTGGAAATAAGGTCGGAGAACACATTAACAAAATTCACGGGAATAATTTAAAACCTTGTAAAATATGTTGGAAAGTATTCAGCGATATGGACGAACTCAAAAATCATATTGAAAATCATCCGGTAAAAGAAGACTCTCCTAAAGCAACTACGCCTATTAAAAAAACGATTGAGCCTAAACCAAAAACTCCCAAACTATATGGACTTCCAAAAGAACTAGCTGAATTAGGTTTCAATGAAGAGCAACAGAAAAGTTTAAAACGAGACATAGACGACGTTACGTCCGATATAAACACAAAGAGACTGAGAAAATTACATTCTTGTACAGTTTGCTATAAAAGTTTTAGATTTGAAACAGACTTGTATGATCACAAAAGAGAAGAGCATTCTATTATTGAAGAGAACTATATGGAAGAAGAAACTGTTAGCAAGGAACCAGAGCCATCATCTGCACCGCCAAGAATTAAAAAGATTGTGTGCGATATTTGTATAGATATTTCTAAAGAATGGATTAGTTTGAAACATTTTTGGCAACATCTAATTAGAGCTCATCGTGCAGAGGCTGCTTTTGTTTGTGGCATTTGCTGTAAAACAAATGCGAGTTATGATGCTTTGGCCATTCATTTGGATAATCATCATCCTAACGCCACAATTATATCATCATTTGCCTGTGACGTATGTGGTCGCAATCACAATGCGTCTTCCAAACTTCAGAAACATCGTCTTATACATTCAAATGCACCTCTTGCATTCCCGAAATTTCATTGTGACGAATGTGAACTTGTGTTCAATTCAAAATCATTTGGGGAAAAGCATATTTTATCCCATGGTCCTGGCAGTAAATTATGCAAAGGCAAAGACTTATGTCAGGAAATGGATGATGACATGCTGGAAGAACaaatggaagaagaagaagaagatgaagaagtagttgaagacgccggagacccggaaacagaaactaaagacgacgatgatgatgatgaggaggaagaagaagaagttgaacaaaacgatgatgacgacgatgatgatgaagaagacgataatgaacaaaatgacgatgatgtagaagaagatgaagaggaaactgaacagaacgcagatgacgacgatgatgacgaacaaaacgacaatatagacgtcgaagaagataaagaacaggttgaaggagatgacgacgaagaagatatagaagaaaatggtgttgacgaccaagatgatgacgaagacgaagatcaagatgatgatgatgacgacgatgatgaagacgacgaagatgatgatgacgaggaagaACTTTAG
Protein Sequence
MSRLHHIQPEVSIFAVSPNPPSKPRKIKSQPPALKPAIWPTTKPPVASMHLQQFLKAHRLSQKPPVQREPPPLNKMQYFANDSRTEYQKQQQQMHQKLVQQRMANNNSIREDSPNPMDFLEIGVHAGNSIINNIPKEVKSKTNLKSGGSSIISQTDTSSRRKNANPRKVARENEIEPPGPSNHFLLSQTKPDNLRQSCLLCERNFGNKYDLSQHISEVHGIEPSDLHQLNGNLADDDEFVESMMEAETVFFCEVCTREFQDKASLWLHMVRGHKQEAAVTCGVCMKICNDSKSLMEHVNTQHPKSSDTADSIQRRYRCQVCARQHDTKKKMMRHVVIHTVYDNDGQIIDPDKLIIINNNFHPTKASNNEHYTISCQVCHKVFPSEEKLLRHMSSVHLMTVCDDMITTTTVTTTGNSSQSSFVNRCELCGESCGSRTEKWWHVLKEHGTNEALICPKPDCRKLFVSQSLQIEHQSHHEAQGDLPNTCEVCGRLWPNRNDFYKHIMAVHAECMPLLCGICLKVHIDVPKLREHIKEKHEPLVSKENAIYCDICGRTYTKWSKMMRHRAIHNVEDQVSHFVTDQLTEVNLKCTLCPDTEFKTVEEISEHRKNDHQLHVCDLCSKYYSGNNHLWKHVSRQHKGHPDVTCSLCARTSASKVHLKRHMIKYHSDPVDQLIDKSNNSSCAEINSIHQCIRCDKVFRIRSLLKKHLKYCKGKKDAMAKEKGHFPCPKCPKTFDYHTHLNRHLRQSHLVQYCELCSEDKSGEHFDNKMLLMDHIREKHSKDPELCCDVEGCDKVMRTKTDCQKHKRDHIRKVFSYVCEFCGDMHSNKKNYRKHLRQRHKGNTQYLCGVCMELCVDVDGLSKHLHEAHPQTFTKSNICQICGKIFTVGNKVGEHINKIHGNNLKPCKICWKVFSDMDELKNHIENHPVKEDSPKATTPIKKTIEPKPKTPKLYGLPKELAELGFNEEQQKSLKRDIDDVTSDINTKRLRKLHSCTVCYKSFRFETDLYDHKREEHSIIEENYMEEETVSKEPEPSSAPPRIKKIVCDICIDISKEWISLKHFWQHLIRAHRAEAAFVCGICCKTNASYDALAIHLDNHHPNATIISSFACDVCGRNHNASSKLQKHRLIHSNAPLAFPKFHCDECELVFNSKSFGEKHILSHGPGSKLCKGKDLCQEMDDDMLEEQMEEEEEDEEVVEDAGDPETETKDDDDDDEEEEEEVEQNDDDDDDDEEDDNEQNDDDVEEDEEETEQNADDDDDDEQNDNIDVEEDKEQVEGDDDEEDIEENGVDDQDDDEDEDQDDDDDDDDEDDEDDDDEEEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00340860;
90% Identity
-
80% Identity
-