Basic Information

Insect: Dorcus parallelipipedus
Gene Symbol: GFI1B
Assembly: GCA_958336345.1
Location: OY284475.1:2412920-2421553[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.00047 0.043 15.7 5.1 3 23 169 189 167 189 0.98

2 24 1.4e-05 0.0013 20.4 3.9 1 23 195 217 195 217 0.98

3 24 3.2e-06 0.00029 22.5 5.7 1 23 222 244 222 244 0.99

4 24 7.8e-05 0.0072 18.1 1.1 2 23 251 273 251 273 0.96

5 24 0.029 2.7 10.1 0.2 1 23 278 300 278 300 0.97

6 24 6.9e-05 0.0064 18.3 1.3 1 23 310 332 310 332 0.97

7 24 0.00045 0.042 15.7 0.1 1 23 338 360 338 360 0.98

8 24 0.00033 0.03 16.2 4.6 1 23 366 388 366 388 0.97

9 24 1.5e-05 0.0014 20.4 2.0 1 23 394 416 394 416 0.98

10 24 0.0035 0.32 12.9 1.9 5 23 425 443 422 443 0.95

11 24 0.0059 0.54 12.2 0.9 1 23 463 485 463 485 0.98

12 24 4.9e-05 0.0045 18.8 1.6 1 23 491 513 491 513 0.99

13 24 0.051 4.7 9.3 3.8 1 23 529 551 529 551 0.99

14 24 0.13 12 8.0 2.8 1 23 557 580 557 580 0.97

15 24 0.031 2.9 10.0 4.5 1 23 586 608 586 608 0.94

16 24 0.6 56 5.9 0.2 2 23 734 755 733 755 0.91

17 24 0.017 1.6 10.8 5.0 1 23 761 783 761 783 0.97

18 24 0.0061 0.57 12.2 1.9 1 23 789 811 789 811 0.91

19 24 0.001 0.093 14.7 3.2 1 23 817 840 817 840 0.98

20 24 0.0014 0.13 14.2 3.0 1 23 852 875 852 875 0.95

21 24 0.018 1.6 10.7 0.8 3 23 886 906 885 906 0.98

22 24 1.8e-05 0.0017 20.1 4.2 1 23 912 934 912 934 0.98

23 24 4.3e-06 0.0004 22.1 0.8 1 23 940 962 940 962 0.98

24 24 0.23 21 7.2 0.1 1 21 968 988 968 989 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.00047	0.043	15.7	5.1	3	23	169	189	167	189	0.98
2	24	1.4e-05	0.0013	20.4	3.9	1	23	195	217	195	217	0.98
3	24	3.2e-06	0.00029	22.5	5.7	1	23	222	244	222	244	0.99
4	24	7.8e-05	0.0072	18.1	1.1	2	23	251	273	251	273	0.96
5	24	0.029	2.7	10.1	0.2	1	23	278	300	278	300	0.97
6	24	6.9e-05	0.0064	18.3	1.3	1	23	310	332	310	332	0.97
7	24	0.00045	0.042	15.7	0.1	1	23	338	360	338	360	0.98
8	24	0.00033	0.03	16.2	4.6	1	23	366	388	366	388	0.97
9	24	1.5e-05	0.0014	20.4	2.0	1	23	394	416	394	416	0.98
10	24	0.0035	0.32	12.9	1.9	5	23	425	443	422	443	0.95
11	24	0.0059	0.54	12.2	0.9	1	23	463	485	463	485	0.98
12	24	4.9e-05	0.0045	18.8	1.6	1	23	491	513	491	513	0.99
13	24	0.051	4.7	9.3	3.8	1	23	529	551	529	551	0.99
14	24	0.13	12	8.0	2.8	1	23	557	580	557	580	0.97
15	24	0.031	2.9	10.0	4.5	1	23	586	608	586	608	0.94
16	24	0.6	56	5.9	0.2	2	23	734	755	733	755	0.91
17	24	0.017	1.6	10.8	5.0	1	23	761	783	761	783	0.97
18	24	0.0061	0.57	12.2	1.9	1	23	789	811	789	811	0.91
19	24	0.001	0.093	14.7	3.2	1	23	817	840	817	840	0.98
20	24	0.0014	0.13	14.2	3.0	1	23	852	875	852	875	0.95
21	24	0.018	1.6	10.7	0.8	3	23	886	906	885	906	0.98
22	24	1.8e-05	0.0017	20.1	4.2	1	23	912	934	912	934	0.98
23	24	4.3e-06	0.0004	22.1	0.8	1	23	940	962	940	962	0.98
24	24	0.23	21	7.2	0.1	1	21	968	988	968	989	0.94

Sequence Information

Coding Sequence: ATGTTCAACCGGCAACTTTTTAACCCAATTCAATTGAATGATTATGATCAACAGTTCAGTGCCATCTATCACAACACCTTATACAACGCAAACTACAACTTCCAACAGCCAACCGAGTCTCTCAACTTGCAATCAAAGTACTTCCTGATGATGGTCAACAAAGAACAGGCGCCCGTACTGCCAGAGAACAACCTGCTCGAGTCCGCCGTTGACCAACTGAACGACACGGACGCGGAGCTTTTAAATCTGTTGGCCGACGAGGGCGATTGCACCGACATACTGCAGAACATAGCGAACAATGAGCAGTTCGAACAGCTGATCAACGACGGCGCAGATTTCGGCGCCGCGGATAATTTGGCGCGCGAGCTCATGGGGCCGGAAAATTACGACGGGTTGTGCCATACGATCCAAGAAGCTGACCTGAACGAGATCATCCTGGACGACATGGCACCTGCGGTGAAGACGCCGCCGGATGAAAGCAAGCAGCCGCAGCAAGGTTTCGGATGTGAGCACTGCGATAAAGTCTGCACGACGAAGAAACTGCTGAAGTATCACCTGATGACGCACACGGGCGCGAGGCCCTACTCCTGCGACGTTTGCGGCAAGACGTTCAAGCATAATTACGAGGTGAAGACGCACAAGCGAAGTCACAATCGGCCGACCTTCCAGTGTGATATCTGCTCGAAGATGTTCATACACAAGTCACACTTGACCGCGCACAGGCGGAAGCACCTCGGCGATTTCGTCGCTTATTGCAAGGATTGCAACAAGGGTTTTATATCGCAGAGCACATACAAGAACCACGTCAAAGTCCAGCACGAGAAGGTCCTGCACGTTTGCGACGTTTGCGGCGCGCAGTTGAGCTCCATGTCGGCCTTGAGCGAGCACAAGCTGACGCACGATCCGAACTATAAGAACCAACGGACGCACGTGTGCGAGATTTGCGGTAGGAGTTACCTGACGGCGAGGAACCTCCGCAGCCACATGAAGAGCCACACGCAATTGCACAATTTCATTTGCAACATCTGCGGCAAGGCGCTGAGCGGAAAGAAGGTGCTGGAGACGCACATTAagatacacaccggcgagaaggaCTTCGCCTGCCAGTACTGCAGCAAGTGTTTCAGTTCGAAGAAGTACGTGACCATACACGAGAGGACGCACACCGGAGATAAGCCTTTCAAGTGCGAGATTTGCAGTAAGTTATTTACCCAGAAGACCTCGCTCAACGTTCACCTGAGGTACCACAGCGGAGAAAGACCGTACAAGTGCCAGTGTGGTAAGGCGTTTGTCACCAAGACGCACCTGGTGGGGCATTATAAAACGCACGAAATCGAAACTAAGATAGTCGGAGAGGAATTCCCGACGAAACGGCTTGCCAAGTTGTTCATCTGCAGCGTCTGCAATTACCAGTCGGCGCACATCGCTAATTTCAGGCTGCACATGCgcatacacaccggcgagaaaccgttccaGTGCGCCACTTGCCCCTACAGCACCGGCAACAAAGGCAACTTCCGCAAGCACATGCgcaagcacaccggcgagaaaccctACAAGTGTACCCTTTGCAAGTTTAAGAGATACCGATGCGTCACCTGCGCCTACCAAACCGACCGCAGGGAGCATTACAAGCGACACCTTATGACGCACACGGGCGAGTGTCCGTACAAGTGCAAGTTCTGCAGCTACGGCACGATCCACCGCTGGCTTCTGTTGAGTCACGTGCGGAATAAGCACACCGGCGAGGCGCGATACCGGTGCGATTCCTGCGATTACAGGTGCGACACGCTTTACCATCTAAACAGGCACAGCGTCGTCCATAAGTCACTGCCGGGGAGTGGTTACCCGGTCGACTTTTCGGTACAGTACGATTTAGCCGGACTTAACCCGCCGAAAACGGCCGGGGAATGCCTGAGGGTTAAGACTGAATTGTTCCCATCGAAAACGGCCGGGGAATGCCTGAGGGTTAAGACTGAATTGTTCAAATCGATCGAAAGCGACCCGATTTTGAGGAAACTAATATTCGGGCCGTCGATGTCGATTACGATTAAGCAACGACCCGCGAAACCGTCGGCGGTCATCGACGAAGAAGATTCGGAGTTGAAACGGCAGCAGCAGCACCTCAAGCGGAAGCGCTCGAAGGAAAACATTGACTTGGGCGAGGGGCACAACGCCGGCGACTTCAGCGAAGCGATCGAGTGCGAGATCTGCGAGAATACTTTCAAGGACAACCTCGAATTCGGACTGCACTCGATTAAGCACAGCGCCAACCAGAAGTTCTCCTGCCACATGTGCAAGTACTCGAGCGCTTCGAAGTACCATTTCGAGATGCACGTCCGGGCGCACGAGGGCACCACCAAGTACAAGTGTGAGATTTGCAACAAGGCCTTCACCGTCAGCACGCACGCCATCGAGCACAAGTACTtccacaccggcgagaaaccgttccaGTGCGAGATTTGCGGAAAACACTTCATGTTCTCCTGGTTCTTGTCTTCGCACCGTCGGTCGCAACACTGGGAGATAATGACCGGAATGCCTTTGGTTAAATACGACTGCCTTATCTGCAACAAGCATTACACGAGCTCCACGGGTCTGAAGCGCCACAAGATCAGCAAGCACAACGACGGCTGCGCCGAGACTTCCGTGCTGTGCGATATCTGCGGGAAAAGGCTTGCCAGTAAGGAGAAGCTGAAGTTCCATCGCAGAATCCACACGGGTTATAAACCGTATTCGTGCGAGTTTTGCAGCAAGTGCTTCTCGCGCAAGGAGCAGCTCAAGGAGCACGAGAGGATCCACACGGGGGAAAAGCCGTACATCTGCAAGTTTTGCGGAAAGGGCTTCACGCAAAGAAGCCCGCTGAGGATACATGAGAGGACTCACACCGGCGAGCGGCCTTACGTGTGCAGGCTGTGCAACAAGGGCTACATCTCTAAAGGTGTGATGGACACTCACATGAAAAACTGCCAAGGTTTACTCTGA
Protein Sequence: MFNRQLFNPIQLNDYDQQFSAIYHNTLYNANYNFQQPTESLNLQSKYFLMMVNKEQAPVLPENNLLESAVDQLNDTDAELLNLLADEGDCTDILQNIANNEQFEQLINDGADFGAADNLARELMGPENYDGLCHTIQEADLNEIILDDMAPAVKTPPDESKQPQQGFGCEHCDKVCTTKKLLKYHLMTHTGARPYSCDVCGKTFKHNYEVKTHKRSHNRPTFQCDICSKMFIHKSHLTAHRRKHLGDFVAYCKDCNKGFISQSTYKNHVKVQHEKVLHVCDVCGAQLSSMSALSEHKLTHDPNYKNQRTHVCEICGRSYLTARNLRSHMKSHTQLHNFICNICGKALSGKKVLETHIKIHTGEKDFACQYCSKCFSSKKYVTIHERTHTGDKPFKCEICSKLFTQKTSLNVHLRYHSGERPYKCQCGKAFVTKTHLVGHYKTHEIETKIVGEEFPTKRLAKLFICSVCNYQSAHIANFRLHMRIHTGEKPFQCATCPYSTGNKGNFRKHMRKHTGEKPYKCTLCKFKRYRCVTCAYQTDRREHYKRHLMTHTGECPYKCKFCSYGTIHRWLLLSHVRNKHTGEARYRCDSCDYRCDTLYHLNRHSVVHKSLPGSGYPVDFSVQYDLAGLNPPKTAGECLRVKTELFPSKTAGECLRVKTELFKSIESDPILRKLIFGPSMSITIKQRPAKPSAVIDEEDSELKRQQQHLKRKRSKENIDLGEGHNAGDFSEAIECEICENTFKDNLEFGLHSIKHSANQKFSCHMCKYSSASKYHFEMHVRAHEGTTKYKCEICNKAFTVSTHAIEHKYFHTGEKPFQCEICGKHFMFSWFLSSHRRSQHWEIMTGMPLVKYDCLICNKHYTSSTGLKRHKISKHNDGCAETSVLCDICGKRLASKEKLKFHRRIHTGYKPYSCEFCSKCFSRKEQLKEHERIHTGEKPYICKFCGKGFTQRSPLRIHERTHTGERPYVCRLCNKGYISKGVMDTHMKNCQGLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00465180;
90% Identity: iTF_00465180;
80% Identity: -