Basic Information

Insect: Dorcus parallelipipedus
Gene Symbol: Hr39
Assembly: GCA_958336345.1
Location: OY284482.1:32551953-32559376[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.14 3.5e+03 -1.5 6.5 72 192 156 273 110 327 0.46

2 3 4.7e-09 0.00012 23.1 0.1 1 69 403 472 403 528 0.67

3 3 3.1e-74 7.7e-70 237.8 0.3 201 408 513 733 457 733 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.14	3.5e+03	-1.5	6.5	72	192	156	273	110	327	0.46
2	3	4.7e-09	0.00012	23.1	0.1	1	69	403	472	403	528	0.67
3	3	3.1e-74	7.7e-70	237.8	0.3	201	408	513	733	457	733	0.86

Sequence Information

Coding Sequence: ATGGCCGCCGACATGAGGTCACCCAACGTTTCCGTAACCCCCATCAACATGGAGCCCTATCCCCCCGCTGTATCCTTGGCTAATGGCGACCTCCAGGGACATACCCACCTCATCGGAGACCGCGGAGATCTTTCGCAAAACGGGCCGCACATGTCAGTAATTTCCAAACATGAACCTCTGGATAGTTCCGATGCGGAGGTGGCCCAAATCGATTTCCAATCCAGCGTCAACATGAGATCGAAAAAGAAAAGGGGCGGCGAGGGTTGCGAAATTCCCCGACCCATGTCCTGGGAGGGGGAGTTATCAGACGGCGAGAGGGATATGTGCATCGATGAAGATCATCATAACGCATCACAGATTCCTGAAAATTTATCGTTATCACAAAACAAGCTGGCACAAGTAAACGCCCGCGATTCGAAAGAAAGCCCCATTCTGCGACTGAAACAGCCACCGGTGAGCAACTACTCTTTACACAGCACCCCGAGCAATTCGCCTTTGCTTAGCCAGCGACATCCTGTCACGGGAGTCCCCATTTTGGGACACAAGGATCTCATCCACAAGGAAATCATGCACAAGAGCCTCAACGTCCCGCCGACACCGAGCCCCGACTCGGCCATTCATTCCGCCTATAGCGTCTTCAGTTCCCCAAATCAGAGCCCTTTGACTCAAAGGCATGTTACTTTGACGCCGAATTTGAGCAGAAATAACAGCGATGCGTCACATTCGAGCTGTTACAGTTGCTCCAGTGTGTCTGTATCAGTATCGCCCACTCAACAGTTCTCACCTACTCATAGTCCTATTCAGGGTCGGCATATGCCGAACCTTCACAACAGTCCCTTACATCACAACGTCCTTTATCGCAGTGTCCAGGAAGACCCGGGCATTCAGTACAACCCGGATCAGGAAGGCATCGAAGAAACCGAAGATAAGACTGGTCTAGTACATACCCCGCTTACAGCCCAAACTGGCATCTCGAGACAGCAACTCATCAACAGCCCTTGCCCCATCTGCGGCGACAAAATATCGGGCTTCCACTACGGCATCTTTAGTTGTGAATCTTGTAAGGGTTTTTTCAAACGAACTGTTCAGAACAGAAAAAATTACGTGTGTTTGCGCGGAGCGGTTTGTCCCGTCACGGTGGCCACTCGAAAAAAATGCCCCGCCTGTCGCTTTGATAAGTGCTTGAACTGCGGAATGAAACTAGAAGCTATCAGGGAAGATAGGACTCGAGGAGGAAGATCGACATATCAGTGTTCATATTCTTTACCCCCGTCACTCGCCAGTCACTCAGAATTGCGAGCTAGCTCCGGTGATCTACGACATTCGGTCAACGAATCACATCCGGGTTTAACTGTCAAGTTAGAACCGTCTGATTCTGGAATCTCATCTTATTCGAAACGGATCAATTCTAATTCTAGACATAGTGTCCCACCATTATTGCaaGAAATAATGGATGTGGAGCATTTGTGGCATTACAGCGAGTTAGAGTTGAACAAGCTGAATTCCGAAGGAAATTTCACAAAAGAAGGCTCGAGCGGGGGAGTCCACAGTTTATCCACACATCCTTTACTGGCAGGAACAGGACTGGCAGGTTCGACCGATACCAATCCGGATTTCGTTGCGAATTTGTGCAATATCGCCGATCATCGGCTgtacaaaattgttaaatgGTGCAAGAGTCTGCCCCTATTCAAAAATATATCCATCGATGATCAAATTTGTTTACTCATAAATTCCTGGTGCGAATTGCTCCTGTTCTCGTGTTGCTTTCGCTCGATGTCTTCTCCCGGTGAAATCCGGATTTCCCTGGGGAAGAGCATCACGTTAGCGCAGGCCAGGGAAATGGGCATGCAGGCATGCATAGAGCGCATGCTCAACTTCACAGAGCAGCTGAGGAGATTACGCGTCGATAGATACGAGTACGTCGCAATGAAAGTAATCGTATTGCTTACGTCGGatacaTCGGAATTGCGTGAAGCAGAGAAAGTGCGGGCGTCACAAGAGAAGGCTCTTAAAGCTTTGCAGGATTATACGTTACTACACTATCCGGATAGTCCTGCGAAATTCGGTGAACTCTTGCTTCGAATACCAGAGCTGCAAAGAACTTGTCAGGTTGGAAAAGAAATGCTGACAATAAAAACGAAAGATGGTGAGGGGCCGAGTTTTAATCTTCTCATGGAGTTGCTCCGAGGGGACCACTAG
Protein Sequence: MAADMRSPNVSVTPINMEPYPPAVSLANGDLQGHTHLIGDRGDLSQNGPHMSVISKHEPLDSSDAEVAQIDFQSSVNMRSKKKRGGEGCEIPRPMSWEGELSDGERDMCIDEDHHNASQIPENLSLSQNKLAQVNARDSKESPILRLKQPPVSNYSLHSTPSNSPLLSQRHPVTGVPILGHKDLIHKEIMHKSLNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHVTLTPNLSRNNSDASHSSCYSCSSVSVSVSPTQQFSPTHSPIQGRHMPNLHNSPLHHNVLYRSVQEDPGIQYNPDQEGIEETEDKTGLVHTPLTAQTGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAVCPVTVATRKKCPACRFDKCLNCGMKLEAIREDRTRGGRSTYQCSYSLPPSLASHSELRASSGDLRHSVNESHPGLTVKLEPSDSGISSYSKRINSNSRHSVPPLLQEIMDVEHLWHYSELELNKLNSEGNFTKEGSSGGVHSLSTHPLLAGTGLAGSTDTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSSPGEIRISLGKSITLAQAREMGMQACIERMLNFTEQLRRLRVDRYEYVAMKVIVLLTSDTSELREAEKVRASQEKALKALQDYTLLHYPDSPAKFGELLLRIPELQRTCQVGKEMLTIKTKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01498957;
90% Identity: iTF_01258164;
80% Identity: iTF_00466472; iTF_00466240;