Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.55 7.6e+02 1.8 0.0 26 44 9 27 3 31 0.86

2 9 0.02 28 6.4 0.0 21 44 32 55 28 59 0.89

3 9 0.019 26 6.5 0.1 21 43 60 82 57 88 0.89

4 9 0.029 41 5.9 0.4 23 46 90 113 85 119 0.84

5 9 0.27 3.7e+02 2.8 0.1 21 43 116 138 113 142 0.89

6 9 0.0071 9.9 7.9 0.0 21 44 144 167 139 172 0.90

7 9 0.014 19 7.0 0.1 21 50 172 200 169 203 0.82

8 9 0.16 2.3e+02 3.5 0.0 21 44 200 223 197 228 0.89

9 9 0.0032 4.5 9.0 0.2 21 44 228 251 224 257 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.55	7.6e+02	1.8	0.0	26	44	9	27	3	31	0.86
2	9	0.02	28	6.4	0.0	21	44	32	55	28	59	0.89
3	9	0.019	26	6.5	0.1	21	43	60	82	57	88	0.89
4	9	0.029	41	5.9	0.4	23	46	90	113	85	119	0.84
5	9	0.27	3.7e+02	2.8	0.1	21	43	116	138	113	142	0.89
6	9	0.0071	9.9	7.9	0.0	21	44	144	167	139	172	0.90
7	9	0.014	19	7.0	0.1	21	50	172	200	169	203	0.82
8	9	0.16	2.3e+02	3.5	0.0	21	44	200	223	197	228	0.89
9	9	0.0032	4.5	9.0	0.2	21	44	228	251	224	257	0.90

Coding Sequence: ATGCACGCCGACGAGAAGCTCCTCAGATGTGCCGTCTGCGATTACAGATTCAAGGACACCGGAAAGCTGCGACGGCACATGATGtcacacaccgacgagaagccgttcggctGCGAACACTGCGACTATAAATGCCGAGACTCCACGAAACTGAAACGGCACATGTTGATACACAGCGACGAGAAGCCGTACTTCTGCGGcctctgcgattacaaatgccgcaCCGCCAGGAATTTAAAACTGCACGAGTTCATCCACACCGGCGACATGCCGTTCAGTTGCCAGCTCTGCGAATACAAGTGCCGGGATTCCACGAGGTTGAGACAGCACATGCTGgtgcacaccggcgagaagccgtacagttgcgatctttgcgattacaagtgtcgGGGGCCCAGGGATCTGAAACTGCACAAGTTGGTACACACCGGTGAAATGCCGTTCGCTTGTgaactttgcgattacaaatgccgcgAGTCGACGAAGCTGAAACGGCACATGCTAACGCACACCGgggagaaaccgttcagttgcgacTATTGCGATTACAGGTGTTTAACATCGGCGAACTTGAAGCGGCACATGTTGACGCACACCGCCGAGAAACCGTACGGTTGTGAGCTTTGCGGTTGTAAATTCCGACAGCTCCCGCATTTGAAGGGGCACATGTTGACGCACACCGGAGAGAAACCCTTCAGCTGTGACCTTTGTGATTACAAGTGCCGACAGTCCGCTCATTTGAAGCAGCACATGTTGACACATCAACGGCGAGGAGCTCTTCAAATTTAG
Protein Sequence: MHADEKLLRCAVCDYRFKDTGKLRRHMMSHTDEKPFGCEHCDYKCRDSTKLKRHMLIHSDEKPYFCGLCDYKCRTARNLKLHEFIHTGDMPFSCQLCEYKCRDSTRLRQHMLVHTGEKPYSCDLCDYKCRGPRDLKLHKLVHTGEMPFACELCDYKCRESTKLKRHMLTHTGEKPFSCDYCDYRCLTSANLKRHMLTHTAEKPYGCELCGCKFRQLPHLKGHMLTHTGEKPFSCDLCDYKCRQSAHLKQHMLTHQRRGALQI

Sequence clustering based on sequence similarity using MMseqs2