Basic Information

Insect
Dorcus hopei
Gene Symbol
-
Assembly
GCA_033060865.1
Location
CM065419.1:41825048-41827296[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.57 63 5.8 0.7 2 20 165 183 164 185 0.94
2 16 0.00058 0.065 15.2 2.2 1 23 189 211 189 211 0.97
3 16 0.027 3 10.0 0.7 2 21 265 284 264 285 0.93
4 16 0.012 1.4 11.0 1.0 1 23 289 311 289 311 0.96
5 16 0.43 47 6.2 2.0 2 21 374 393 373 394 0.95
6 16 0.013 1.4 11.0 3.0 1 23 398 420 398 420 0.97
7 16 9.4e-05 0.01 17.7 1.6 1 23 428 450 428 450 0.94
8 16 1.7e-05 0.0018 20.1 7.9 1 23 456 478 456 478 0.99
9 16 0.00057 0.063 15.2 0.6 1 23 487 509 487 509 0.97
10 16 4.5e-05 0.0049 18.7 2.2 1 23 515 537 515 537 0.97
11 16 2.2e-05 0.0025 19.7 2.1 1 23 543 565 543 565 0.98
12 16 4.6e-05 0.005 18.7 2.9 1 20 571 590 571 594 0.95
13 16 9.1e-05 0.01 17.7 0.1 1 23 600 622 600 622 0.92
14 16 5.7e-06 0.00063 21.5 4.2 1 23 629 651 629 651 0.98
15 16 4.5e-05 0.005 18.7 5.0 1 23 657 679 657 679 0.97
16 16 0.00051 0.057 15.4 6.5 1 23 685 707 685 707 0.98

Sequence Information

Coding Sequence
ATGGCTAAAGTATGTCGCCTTTGCCTGCAAATAATAGGAGATGCGTATTATTCCATCGATGAGAACGCTGTAGTAAGAAGTCGAAACAAAATTATGATTTTAATGCCAGAACTGGAACTGAATGTTGTTGCTGAGCCTATTCTTTGCCCTTTATGCTATGGCACATTACATGCTGCATACGAATTCAAGTGCATCTGTCTAGCTAACGAACAAAGAATCGTCGAGTATTTGAAGAACGATAAGCAACCCCCGATAAACTTATGCGACTTATTAGAAGAAACTGATTCAAAAACTGTAATTCCAGCGAGCTTAATGGGTGAAAATTTTGGAATAATTGTCAATGATTTGGAGACTGTGAAGAAAGAAAGTATATTAAAGCCAGAGCCATTAGAAGTTTTATGTGAGGTTGACAATGTATTCACTGACTCATTTAAAGAAGCAGAAAGGAACGAGGCAGATAAAAAGAATGAGACACTTGTTAAAGGTGGCatgaaatgttcaaagtgttccaGTGAATTTACAGTTTTCAAGGAATATCGAAAACACTTGGCCCAATGTACAACCTATGAATGTAACATatgcaataaacaatttaaattaaagagtAGATTTGTAAAACATAAGGCGATGCATTGTACAGAAACTGGGAAAGACGTGCAAGTTGCACAAAAAGATTCGGATAGGGAAACGAGTGCAAGTCCTGAACCAGAACAAGATAAAAGCATGAATCTAGAAAATAATGAATGCGAAAGTCTCACTCCAAAAGAAGAGAAAAGCACTGCAGGAAGTGTCAAGTGTTCAAATTGTTCCACGGAGTTTACAGTCTCCAAGCTGTATAGgaaacatttagaaaaatgttccCCCTACGAGTGTGACATCTGtaacaaaaaatttatgttagagGGAAGGTTTTTACGTCACAAATTATCACATAAAACCAGCGGAAAGAAAGGTAAAGGTGGCAGTGCGCACGTTAATacatcaaataaattaacaCAAAGCATAGGTGAAGAAGAAAGTGTAAAAGAAGAATCAGAAAAGGAAGTGAGTGCGAATCCCGAGGCAGACGCGGACGATACTACAGAGAAAAACAGTGAGACTGAAATTAAACTTGGGattaaatgttcaaagtgcCGCAATAAATTTATGCTTAAAAAAGATTATAAAAGACATGTAAGACAATGTGCTCCGTACCAGTgtgacatttgcaataaaaaatttatgttggaaaatagatttaaaaagcaTAAGTTATCGCATAGCACAACTACAGAACAAACATTTTTGTGTGAAGTGTGTAGTAAGACATTTCGAAATTCATATCTCTTTCGACAACACCTCCTGCTGCACACAGGGCTGAAGCCCTTCAAGTGTCCGACGTGTGATAAAATGTTTGCAACGAAACATCATTTATGTGCACATAAACAAACGCATTTGAACAAGATAAGAGAGAGGCGACATGTGTGTGAAATCTGTGGGAAGAAGTTTGCAGCTTTTGTGGTATTGCGAAGGCACAGAATTACACACTCGCAGGAGAAGAAGTTTTTCTGCAAAATCTGTGATAAGGGTTTCAACATCAAAATGTATTTACAACAGCATATGAAGAGGCATGTAGGTGAAAAACCATATGTGTGTGACACTTGCAATTCGTGTTTTGCCTCGAAAAGTAATTTGGCAGAACACTATCGCAGTCACACTGGAGAAAGACCTTATAAGTGTAAGATGTGTGAAAAGAGCTTCGCACAAAGCAGCACATTAAGGGTGCATGTCCAATGCACACATTCTGACGAGAAGCCCTTCGCTTGTGAAGTGTGTGGAAAAAGATTTCCTCTGAAAGGCAACCTTCGAGCACATTCGGCTTTGCACATGGAAAATGTCGAAAAATTTTCTTGTCCGTACTGTGACAAAATTTTTCACAAGAACAGTTATCTGAAGCAGCACATTAAAAGGCATACAGAAGAGCCGACGCATATGTGTACTTTATGTGAGAAAGGTTTTTTTACATCGCATGAATTGAAGAAACATATGAGGATCCATACTGGAGAAAAGCCTTTTGAGTGTGAAATCTGCCATCAAAGGTATAGTCAGAGGCATAATATGCATGTGCATATGAAAGTGCATTCGAAAGGCCCATGA
Protein Sequence
MAKVCRLCLQIIGDAYYSIDENAVVRSRNKIMILMPELELNVVAEPILCPLCYGTLHAAYEFKCICLANEQRIVEYLKNDKQPPINLCDLLEETDSKTVIPASLMGENFGIIVNDLETVKKESILKPEPLEVLCEVDNVFTDSFKEAERNEADKKNETLVKGGMKCSKCSSEFTVFKEYRKHLAQCTTYECNICNKQFKLKSRFVKHKAMHCTETGKDVQVAQKDSDRETSASPEPEQDKSMNLENNECESLTPKEEKSTAGSVKCSNCSTEFTVSKLYRKHLEKCSPYECDICNKKFMLEGRFLRHKLSHKTSGKKGKGGSAHVNTSNKLTQSIGEEESVKEESEKEVSANPEADADDTTEKNSETEIKLGIKCSKCRNKFMLKKDYKRHVRQCAPYQCDICNKKFMLENRFKKHKLSHSTTTEQTFLCEVCSKTFRNSYLFRQHLLLHTGLKPFKCPTCDKMFATKHHLCAHKQTHLNKIRERRHVCEICGKKFAAFVVLRRHRITHSQEKKFFCKICDKGFNIKMYLQQHMKRHVGEKPYVCDTCNSCFASKSNLAEHYRSHTGERPYKCKMCEKSFAQSSTLRVHVQCTHSDEKPFACEVCGKRFPLKGNLRAHSALHMENVEKFSCPYCDKIFHKNSYLKQHIKRHTEEPTHMCTLCEKGFFTSHELKKHMRIHTGEKPFECEICHQRYSQRHNMHVHMKVHSKGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00466650;
90% Identity
iTF_00466650;
80% Identity
-