Dhop036641.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Dorcus hopei
Gene Symbol
-
Assembly
GCA_033060865.1
Location
CM065425.1:75648569-75661340[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 48 0.048 5.3 9.2 1.5 1 23 28 50 28 50 0.97
2 48 5.8e-05 0.0065 18.4 3.3 1 23 54 76 54 76 0.99
3 48 0.0095 1 11.4 6.0 1 23 82 104 82 104 0.98
4 48 0.0097 1.1 11.4 0.3 1 23 110 132 110 132 0.94
5 48 0.00017 0.019 16.9 4.1 1 23 138 160 138 160 0.98
6 48 0.0072 0.8 11.8 0.1 1 21 166 186 166 187 0.95
7 48 0.083 9.2 8.4 2.7 1 23 188 210 188 210 0.98
8 48 9 1e+03 2.0 5.8 2 23 217 235 216 236 0.74
9 48 0.00019 0.021 16.7 0.7 1 23 248 270 248 270 0.97
10 48 0.0012 0.13 14.2 1.0 1 23 281 303 281 303 0.97
11 48 0.0065 0.72 11.9 7.0 1 23 309 331 309 332 0.96
12 48 0.00084 0.093 14.7 0.6 1 23 344 366 344 366 0.97
13 48 0.0016 0.17 13.9 0.4 1 23 377 399 377 399 0.98
14 48 0.00031 0.034 16.1 1.9 1 23 405 428 405 428 0.96
15 48 4.4e-05 0.0048 18.8 1.8 1 23 436 458 436 458 0.98
16 48 0.041 4.5 9.4 3.0 1 23 463 485 463 485 0.97
17 48 0.0012 0.13 14.3 0.4 1 23 498 520 498 520 0.98
18 48 0.00029 0.032 16.2 1.5 2 23 533 554 533 554 0.98
19 48 0.00078 0.086 14.8 2.9 1 23 560 582 560 582 0.97
20 48 0.0012 0.13 14.3 1.2 1 23 595 617 595 617 0.98
21 48 0.002 0.22 13.5 1.2 1 23 623 645 623 645 0.98
22 48 0.025 2.7 10.1 1.1 1 23 651 673 651 673 0.95
23 48 0.013 1.4 11.0 0.2 1 23 679 701 679 701 0.98
24 48 0.0033 0.37 12.8 6.1 1 23 707 729 707 729 0.98
25 48 0.0038 0.42 12.7 6.3 1 23 735 757 735 757 0.98
26 48 0.0024 0.27 13.3 2.8 1 23 763 786 763 786 0.96
27 48 0.0021 0.24 13.4 1.0 1 23 840 862 840 862 0.97
28 48 2.2 2.5e+02 3.9 3.7 2 23 867 888 866 888 0.95
29 48 0.0026 0.28 13.2 0.3 1 23 894 916 894 916 0.99
30 48 0.001 0.11 14.4 0.4 1 23 922 944 922 944 0.99
31 48 0.0027 0.3 13.1 1.8 1 23 950 972 950 972 0.99
32 48 0.25 28 6.9 3.5 1 23 978 1000 978 1000 0.96
33 48 0.012 1.3 11.1 0.2 1 21 1006 1026 1006 1027 0.95
34 48 0.0019 0.21 13.6 1.7 1 23 1077 1099 1077 1099 0.98
35 48 0.013 1.4 11.0 0.1 2 23 1118 1139 1117 1139 0.97
36 48 1.4e-06 0.00015 23.5 0.8 1 23 1143 1165 1143 1165 0.99
37 48 4e-05 0.0044 18.9 1.0 1 23 1171 1193 1171 1193 0.99
38 48 0.012 1.4 11.0 3.3 1 23 1199 1221 1199 1221 0.97
39 48 0.67 75 5.6 6.4 1 23 1227 1249 1227 1249 0.99
40 48 7.3e-07 8.1e-05 24.3 1.7 1 23 1255 1277 1255 1277 0.98
41 48 0.0067 0.74 11.9 3.3 1 23 1283 1306 1283 1306 0.96
42 48 0.00023 0.025 16.5 0.4 2 23 1379 1400 1378 1400 0.96
43 48 2.8e-05 0.0031 19.4 2.8 1 23 1404 1426 1404 1426 0.99
44 48 0.057 6.3 9.0 4.8 1 23 1432 1454 1432 1454 0.98
45 48 0.0005 0.055 15.4 1.3 1 23 1460 1482 1460 1482 0.98
46 48 0.00058 0.065 15.2 4.0 1 23 1488 1510 1488 1510 0.98
47 48 2.8e-06 0.00031 22.5 1.0 1 23 1516 1538 1516 1538 0.97
48 48 0.002 0.22 13.5 2.9 1 23 1544 1567 1544 1567 0.96

Sequence Information

Coding Sequence
ATGAAGAAGCATGTCTTAACGCATACCAAGAGAAATCCACTCGAACACACGAAGAAGCTTACGACGAAAGTTAAAAAGCAATTCGTCTGTGAGATTTGCGGTTTTAAAACAGATAAACATTGGCGTCTCAGGAAGCACCTCAACGGTCACGAGAGACCGTATCAGTGTGATCGCTGCGGCCACACGTTCGCCGCACTTGCCCATTTGAAGACGCATATGAGGCGACACACCGGCGAAAAACCGTACAAGTGCAACgcttgcgattataaatgcactCAGTCCTGTCAGCTCTGGACGCATATGAAGCTACACACCGGCGCGAAGCCGTTTCTGTGCGACAAGTGCGATTACAGAGCCGCCCTGAAAGGTAACCTCACGAAACATATGGTCTCACATTCCACGGAAAAGCCGTTCAAGTGTAACATCTGCGATTTTGAGACGAAAACTTCCAAACATTTAAAGAGACACGTAAAAGTACACACGGGCGTGAAGGAATTCGAATGTAGCGTTTGCACTATGAGATTTAATGATTCGCAGGGCATAAAAAGGCATATGTTAGTTTTCAAATGCCGATATTGCGATTACAAGGCGAATCGTGCCAGCATTCTCGAGAAACATGTTTGcacgcacaccggcgagaaaccgtacGAATGTAAATTGTGCGACTACAAGCCCGGAAACCTCAAGAGGCACATGAGGCTACATCATGCTAAGAAAAAAGACGAAGGGACAGAACCTGAGTTCGCATGTGAGGTTTGTAACTTTAAGACGGCGCAAGCCGATTATTTGAGGAGGCACATGAAAAGACACAGTGAACAGAAACAGGTCCAGAGCTTGAAGTACAAATGTCAGTACTGTGATTACGAGGCGAGTCGGGCCAGTACTCTCAAGGATCATGTTTTTAGgcacaccggcgaaaagccgCACAAATGTAAATTGTGCGAGTACAGGTGCTCTCTGCCTGGAAATCTCAGGAGGCACGTGAGGCGACATCACGTTAAGAAAAAAGACGAAGTGGCAGAATCCGAGTTTGCATGCGGGGTTTGTGATTTTAAAACGACGGAGGCCGATTATTTGAGGAAGCACATGAAAAGGCACAGCGAACAGAAGCCGGTTCAGAGTTCGAAGTTCAAATGTCAGTATTGTGATTACGAGGCGAGTCGGGCCGGCACTCTCAAGGATCACGTTCTTAggcataccggcgagaagccgcaCGAATGTAAACTGTGCGATTACAGGAGCACTCTGCCCGGAAATCTCAAGAGGCACATGAGGCTACGTCATGCCAAGGAAGCCGAATCCGGGTTCACGTGTGAGGTTTGTGATTTTAAAACGACGCAAGCCGATTATTTGAGGAAGCACATGAAAAGACACGGCGATCAGCGGTTCGCCTGTAAATTGTGCGATTACAAATGCGTCGAGTCCCGAGACTTCAAAAGGCACACGATAATGCATGAGGTGAAGGAAAAAGGCGAGGAGTACGAATATAAATTCACGTGTGATATCTGCGGTTTTAAAACCATTCTAGCTGGTTACTTGAACAAACACATGAAGCAACACGCCGGTCAAAAACCACCGTCTAATTGTGTGTGGCGTAAATGTAATTATTGCGATTATAAGTCGAATTCCCCCGCCACTCTTCGAAAACATATGTTTACCCATagcggcgagaagccgttcgcaTGTAAATCGTGCAGTTACAGGAGTAGCACGTCCAGGAACCTCCAGAGGCATTTGAAAACGCACATGGCGAAAGAAAAGGTCCAGGACGCTGACAAGAAATTCATGTGTGAGGTCTGCAGTTTTAAAACCACTACGGCCAGATATCTGAGGAAACACATGTTGATACACAGCACCGAGAAGCCGTTTCAGTGCGACCGCTGCGGCCAAAAATTCTCGTCGAACACCATCTTAAAGATGCACATGGTGCGACATACCGGGGAAAAACCGTACGAGTGCGACATCTGCGGCTATAAGTGTTATCAGGGCGGCACAATGAAGCGTCACCTCGTGCTGCACACCGGCGTGAAAACCTTTCAGTGCAACAAGTGCGATTATAAGGCGGCCGTAAGAGGTGCCATCACGAAACACATGGCCACGCATTCCACGGAGAAACCGTTCGAGTGCCACGTTTGTAAATACAAGACGAAAACCCCGAATTGTTTAAAAAGTCACATGCTAACGCACACAGGCGAGCGGTTGTATAAATGTAGCACTTGCTGCAAGAGGTTCTCGCGTAGCAAGGACTTGAAAAAGCACACGTTGATACACACGGGGGAGAAACCGTTCGCGTGTAACTTGTGCGATTACAGATCGACCCAGAAGTCAAATGTGACGATACACATGAAGCACAGACATAAGGAAGTTACTGCAAAAAGCGTTGGCATTGAAGAGAACAAAACCGTCTCTCTTACCACAAGACCGCAAACGAAAGAAACGAAAAGACACGTTTTAACATGCGAGTTGAAATATAGCAAATGTTTAAAAGCGCAGCACACGACGGAAGATCAAAAACGATTCGCATGTGAGATTTGCGGTTTCAAAACAGAGAAACGTAGAAATCTCAAGAGCCACGTCAACAGGCACGGGAAATCGTGCCAGTGCGATTGCTGCGGCAATATTTTCAAGTCGCTTGCCATTTTGAAACTACACATGAGGCGACATACCGGCGAAAAACCGTACAAGTGCAACCTTTGCGATTATGAATCTACTCAGGCAGGCACCCTCTTGTCTCACAGTAGGGTACACACCGGCGCGAAACCTTATCAGTGTGATAAATGCGATTACAGGGCTGCGCTAAAAGGTACCCTCACGAGACATATGGTTACGCATTTCGCAGAAAGGCCGTTCAAGTGTGACATCTGCGATTTCGATGCGAAAAGCTCCAGAACTTTAAAGAAACATGTAAAGAAACACACGGGCGAGAAGGAATTCGAGTGTAGCGTTTGCAGTAAGAGATTGGCGTGCTCCAAGAGCCTGAAAAGGCATATGTTCTTACACACGGGGGAAAAGCCGTTTGCCTGTAATTTATGCGATTACAGATCTACTGAACAGTCAAATGTGAAAGTACACATGAAgTTACCTACACAAAGCAACGCAAGTGCGGCTTTTGAAGAGGACGAGACAGTTTCGTGGGTCTCCCCTACCGCAGACATGGGTTCTCTGAATCAGCTGTTTACGAATGAAACATACTTGTTGAAATACTCGTATAGCGTACCTGAAAAGCTATTTAAATGTGAATACTGCGATTACAAATCCGACCGTTCTGCTTCTATGAAGAAACATGTCTTGAGGCATACCAGGAGGAAGCTACTTGAATCCGGGTTGAAATATCCCGGCTTTGAAACTTTGGTGTGTGAGATTTGCGGTTATCAAACAGATGAAGCCGCATATCTCAAGAGCCACCTCAATAAACATGAGAAGTCGTACCAGTGCGATCGCTGCGGCGGTACATTCTCCACGCTTGCCAATTTGAAATCGCATATGCGCCGACATACCGGGGAAAAACCGTACAAGTGCAacgtttgcgattataaatgtatTCAAGCCTCCCAGCTCTGGGTGCATCTTAAGATACACACCGGTGCGAAGCCTTTTCACTGCGACAAGTGCGATTACAAAGCTACTCTGAAGCGCAGCCTCACGAGACACATGGTCACGCATTCCACAGAGAAGCCGTTCAAGTGTAACTTCTGCGATTTCGAGACGAAAACCTCCAGGGATTTAACGTGTCACAAGAGAACGCACACGGGCGAGAAGTCGTTCGTATGTAGTGTTTGCACTAAGAGATTCACCAGGTCCAGAAACTTGAAGAGGCATATTTTAATACATGCAGGAGAGAAACCGTTCGCGTGTAATTTGTGCGATTACAGATCTACTCAGCGGTCAAACGTGAAATTACATATGAAACACAGACATAAGGAATGCGCCGATGGTACACGTTTTGGAGAGAACGAATTTCTTTTGAGGATATCCCCCATCACAGAAACGGAACCGAAGGAAACAGGCTCTGCGAATCAGCTGGTTAAATGCGAACGTGGCGATTCTATGAAGAAACATGTTTTAACGCGTACGAATCTGTCCGTATATCAAATATGCGAGTTCAaatacgttaaaaaaattaaaagacaaagCGTATGCGAGATTTGCGGTTTTAAAACAGATAGAACTGGAAACCTCAAGAGGCACATGAAAGCACACGAGAAATCGTATCAGTGCGATCGCTGCGGAAACACCTTCACCAGAACTACCACTTTGAAATCGCATATGAGGCAACATACCGGGGAAAAGCCGTATAAGTGCAacgtttgcgattataaatgctcTCAGTTCTGTCTCCTCTGGGCACATAATAAGATACACGCCGGCGCAAAGTCCTATCGGTGTAACAAATGCGACTTTAGGGCTACCTTGAAGGGTAACCTCACGAAACATATGGTTACGCATTCCACAGAGAAGCCGTTCAAATGTAACGTCTGCGATTTCGAGACGAAAACCTCCGCACATTTAAAGCGACACGAGAAAAAGCACACAGGCGAGAAGGCGTTCGAGTGCAGCGTCTGTACTAAGAGATTCACTACTGCCAGAAACTTGAAAAGGCACGTTTTAATACATGCAGGGGAAAAACCATTTGCTTGCAATTTATGTGATTACAGATCTACTCAGCGGTCAAACGTAAAAGCGCACATGAAACACAAACATAAGGAATGTGAAAATGCTGCACATAAAATTGAAGCGACATAA
Protein Sequence
MKKHVLTHTKRNPLEHTKKLTTKVKKQFVCEICGFKTDKHWRLRKHLNGHERPYQCDRCGHTFAALAHLKTHMRRHTGEKPYKCNACDYKCTQSCQLWTHMKLHTGAKPFLCDKCDYRAALKGNLTKHMVSHSTEKPFKCNICDFETKTSKHLKRHVKVHTGVKEFECSVCTMRFNDSQGIKRHMLVFKCRYCDYKANRASILEKHVCTHTGEKPYECKLCDYKPGNLKRHMRLHHAKKKDEGTEPEFACEVCNFKTAQADYLRRHMKRHSEQKQVQSLKYKCQYCDYEASRASTLKDHVFRHTGEKPHKCKLCEYRCSLPGNLRRHVRRHHVKKKDEVAESEFACGVCDFKTTEADYLRKHMKRHSEQKPVQSSKFKCQYCDYEASRAGTLKDHVLRHTGEKPHECKLCDYRSTLPGNLKRHMRLRHAKEAESGFTCEVCDFKTTQADYLRKHMKRHGDQRFACKLCDYKCVESRDFKRHTIMHEVKEKGEEYEYKFTCDICGFKTILAGYLNKHMKQHAGQKPPSNCVWRKCNYCDYKSNSPATLRKHMFTHSGEKPFACKSCSYRSSTSRNLQRHLKTHMAKEKVQDADKKFMCEVCSFKTTTARYLRKHMLIHSTEKPFQCDRCGQKFSSNTILKMHMVRHTGEKPYECDICGYKCYQGGTMKRHLVLHTGVKTFQCNKCDYKAAVRGAITKHMATHSTEKPFECHVCKYKTKTPNCLKSHMLTHTGERLYKCSTCCKRFSRSKDLKKHTLIHTGEKPFACNLCDYRSTQKSNVTIHMKHRHKEVTAKSVGIEENKTVSLTTRPQTKETKRHVLTCELKYSKCLKAQHTTEDQKRFACEICGFKTEKRRNLKSHVNRHGKSCQCDCCGNIFKSLAILKLHMRRHTGEKPYKCNLCDYESTQAGTLLSHSRVHTGAKPYQCDKCDYRAALKGTLTRHMVTHFAERPFKCDICDFDAKSSRTLKKHVKKHTGEKEFECSVCSKRLACSKSLKRHMFLHTGEKPFACNLCDYRSTEQSNVKVHMKLPTQSNASAAFEEDETVSWVSPTADMGSLNQLFTNETYLLKYSYSVPEKLFKCEYCDYKSDRSASMKKHVLRHTRRKLLESGLKYPGFETLVCEICGYQTDEAAYLKSHLNKHEKSYQCDRCGGTFSTLANLKSHMRRHTGEKPYKCNVCDYKCIQASQLWVHLKIHTGAKPFHCDKCDYKATLKRSLTRHMVTHSTEKPFKCNFCDFETKTSRDLTCHKRTHTGEKSFVCSVCTKRFTRSRNLKRHILIHAGEKPFACNLCDYRSTQRSNVKLHMKHRHKECADGTRFGENEFLLRISPITETEPKETGSANQLVKCERGDSMKKHVLTRTNLSVYQICEFKYVKKIKRQSVCEICGFKTDRTGNLKRHMKAHEKSYQCDRCGNTFTRTTTLKSHMRQHTGEKPYKCNVCDYKCSQFCLLWAHNKIHAGAKSYRCNKCDFRATLKGNLTKHMVTHSTEKPFKCNVCDFETKTSAHLKRHEKKHTGEKAFECSVCTKRFTTARNLKRHVLIHAGEKPFACNLCDYRSTQRSNVKAHMKHKHKECENAAHKIEAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00465624;
90% Identity
iTF_00465624;
80% Identity
iTF_00465624;