Dhop007286.1
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- LZTR1
- Assembly
- GCA_033060865.1
- Location
- CM065419.1:52831471-52834012[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 7.9e-08 5.3e-05 24.9 0.2 3 107 360 496 358 499 0.79 2 4 0.25 1.7e+02 4.0 0.2 77 109 498 530 490 531 0.86 3 4 3.3e-17 2.2e-14 55.1 0.0 8 95 590 677 584 693 0.84 4 4 0.64 4.3e+02 2.6 0.1 76 101 692 717 682 725 0.81
Sequence Information
- Coding Sequence
- ATGAGTGGAAGTATTAGTGCAGAATCATCTTACAGTGCACTAGACAACGGGTTAACTTTGGAATTCGGGCCTTCGGAAACTGTACACCGTTGGAGACGTATGCCAGAATGTGATGAATTTGTTGGAGCTAGGCGAAGCAAACATACAGTCGTTGCTCAAAACGGGGGCATTTATGTATTCGGTGGCGACAACGGGAAGAGCATGCTAAATGATTTGCTGCGCTTTGACGTGAAAGATATGTCTTGGGGTCGAGCGTTTTCAAATGGTGGCCCCCCTGCACCCAGATACCATCACTCCGCAGTCGTTCATAATAATTCGATGTATGTCTTCGGAGGATACACCGGAGATATACATTCCAATTCAAATCTTACTAATAagaacgatttatttcaatataatttCCATTCGGGACTGTGGACGGAATGGAAATTTACCGGAAAGAAAACTCCCGTTCCAAGGTCAGCACATGGTGCAGCCGTTTATGACAATAAATTATGGATTTTCGCCGGATACGATGGGAATGCACGATTGAATGATATGTGGACAATTTCTTTAACTGGTGAAAACCGAGTGTGGGAAGAAATAGATCAGAAAGGAGAACGTCCACCAACCTGTTGCAATTTTCCTGTTGCTGTAGCAAGAGAATGCATGTTTGTTTTCAGTGGACAAAGCGGAGCAAAAATCACCAACTCGCTCTTCCAATTTAGCTTCAACGACAAAACATGGACACGCATATCAACCGAGCACATTTTACGAGGGGCTCCTCCACCACCTGCTCGAAGGTACGGTCACACAATGGTGGCATTTAATCGTCATCTTTACGTATTTGGGGGCGCTGCTGATAGCACATTGTCTAACGACCTACACTGCTTTGACTTGGACTCTCAGACTTGGTCTGTAATCTTACCAGCAGCCGATTCTTTTGTTCCTTCAGGTCGGTTGTTTCACGCCGCTGCTGTTGTTGGAGATGCGATGTTTATTTTTGGAGGGACAGTCGATAACAACGTTAGAAGCGGAGAAATGTACAGATTTCAGTTCTCCTGCTATCCGAAATGCACTCTGCATGATGACTACGGAAAGCTACTAGAATCTCGACAGTTCTGCGATGTCCAGTTTGTTGTCGGTACTGAAGAACAGAAAATTTTGGGGCATTTGGCGTTAGTAGCCGCGCGTTCGTTGTTTCTGAGAAATAAAATTCGAATTGCAAAAGAAGCCAGAGATGAACACCTGGAGAGGCTGTTTGGAACTATTCACGTGCCGTTTAAAGACGTTCCTTTACTCGACGTTGTCTTGCCTGATGCTAATCCCGAGGCTTTCGAAATGGTTTTGAATTACATTTACATGGACTGCATTGACCCGATTAAAAAGGCTAAACCCGGTGAAGACCCGTTTAGTAATCGCATTGTGCTACTCATGATGGATGTCTATAGATTAGCCTGTACTTTCGACATGGCCCGCTTAGGACATCTTTGCGTGCAGTATTTAAACGCAACAATTTGTTTGAAGAACGTACTCGTTGCTCTGCACAATGCAGATGCGTTACAACTCgattttattaaagaattctGCCTGCGATTCATCGTTAAAGAATCTAATTATAATCAGATCGTAATGAGCACTGAATTTGAGACTTTAAAGCGGACTCTTATGATTGAAATCATAAGGCGAAAACAGTTGCCTCAAGCCAAGGTACAAGTAGATCCACACTTTGACACTGCTGGGTCGTCATTGGAACAGGATATGGCAATGTTCTTGAAGACCACTGGAGAGGAATTCTGTGACATTAATTTATTGTTGGATAGTAGTGTCATTCCTGCACATAAAACGATATTAGCTGCGAGGTGCGGATATTTTGAAGGCATGTTTCGATCTTTTATGCCATCGGATAACACAGTCAGAATTCAAATAGGTGAAATGACTCCGTCAAGAGAATCCTTTGATTCTTTACTGCGTTACATATATTACGGAGATGTGAATATGCCGCCTGAAGATTCGTTATATCTGTTTTCTGCGCCATTCTTCTACGGCTTCAGCAATAACCGCCTGCAAGCGTTCTGCAAACAGAATTTAGAGATGAACGTCACATTTGAAAACGTCATACAAATTCTCGAAGCAGCAGACCGAATGCAAGCGACCGACATGAAGAAATATGCACTCGATTTGATCGTCCATCACTTCACGAAGGTTGCTAAATTACCACGGCTGAAGATGCTAAGCAAGGAGTTGATATTGGATATATTAATGGCCCTTGCAAATGATATGAGCGACATGAAAATGTGCCAAGATATGTCGTCAGTAAGTCTGAACAGCGATTCCTGA
- Protein Sequence
- MSGSISAESSYSALDNGLTLEFGPSETVHRWRRMPECDEFVGARRSKHTVVAQNGGIYVFGGDNGKSMLNDLLRFDVKDMSWGRAFSNGGPPAPRYHHSAVVHNNSMYVFGGYTGDIHSNSNLTNKNDLFQYNFHSGLWTEWKFTGKKTPVPRSAHGAAVYDNKLWIFAGYDGNARLNDMWTISLTGENRVWEEIDQKGERPPTCCNFPVAVARECMFVFSGQSGAKITNSLFQFSFNDKTWTRISTEHILRGAPPPPARRYGHTMVAFNRHLYVFGGAADSTLSNDLHCFDLDSQTWSVILPAADSFVPSGRLFHAAAVVGDAMFIFGGTVDNNVRSGEMYRFQFSCYPKCTLHDDYGKLLESRQFCDVQFVVGTEEQKILGHLALVAARSLFLRNKIRIAKEARDEHLERLFGTIHVPFKDVPLLDVVLPDANPEAFEMVLNYIYMDCIDPIKKAKPGEDPFSNRIVLLMMDVYRLACTFDMARLGHLCVQYLNATICLKNVLVALHNADALQLDFIKEFCLRFIVKESNYNQIVMSTEFETLKRTLMIEIIRRKQLPQAKVQVDPHFDTAGSSLEQDMAMFLKTTGEEFCDINLLLDSSVIPAHKTILAARCGYFEGMFRSFMPSDNTVRIQIGEMTPSRESFDSLLRYIYYGDVNMPPEDSLYLFSAPFFYGFSNNRLQAFCKQNLEMNVTFENVIQILEAADRMQATDMKKYALDLIVHHFTKVAKLPRLKMLSKELILDILMALANDMSDMKMCQDMSSVSLNSDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01186316;
- 90% Identity
- iTF_01258198;
- 80% Identity
- -