Dhop007963.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dorcus hopei
Gene Symbol
Klhl17
Assembly
GCA_033060865.1
Location
CM065420.1:3523021-3529037[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2e-33 1.3e-30 107.3 0.7 3 109 59 163 57 164 0.97

Sequence Information

Coding Sequence
ATGAGTTCCGACTCAGGAGAATCCTCGGATTCGCCCCCTGCGGCGGCCAGCGCCGTCCTGGAAGCCTCAACGCAAACGCCCACGAACGAACACTGCGATTCGCCCATGTTCACCCCGAAGGGGTATTCACTGAAGACGTCGGGGCACAGCAGCCACGCCCTCACCAACATCTTCAAGATGAGGCAACACGGACAGTTATGCGACGTCACCCTAAAAGTAGGGCTGGAGACCTTCAAGGCCCACAGGGTCGTCCTGGCCTCGGTCAGCCCCTACTTCTTCGCCATGTTCAATGGTGAGATGAAGGAGCACGCCAGCTCTGAGGTGGTCTTACACGACGCCGACGCCACCGCCGTCGAGCTCCTTCTCGATTACGCCTACACCGGCCAAATCGTCATCACCGCAGACAACGTTCAGGTCCTCCTCCCCGCCAGTAGCCTCCTGCAAATGCAGGAAGTCCGCGAGGCCTGCTGCAAATTCCTCATGAAACAGTTGCACCCCACCAATTGCCTGGGCATACGCAGCTTCGCAGATACACATTCCTGCACCGAGCTCCACCTGAAATCGCATTGCTACGCCCTGCAGAATTTCCAGCAGGTCGTCGCGACCGAGGAGTTCCTGCTTTTACCCTTCGCGGAGGTCGAAGAGCTGATCTCCAACGGTCAACTGAACATCTCGTCCGAGGAAGACGTCTTTACGGCCGTCCTCAATTGGCTGAAGCACGATCTGGCCAATAGGAGCCAATACGTTTCAAATTTGATGGAACACGTTAGGTTACCCTTGGTGAACAGAGACTTCCTCATGACGAGGGTGGACAACGAGAGGTTGGTGAGGGAGAACAGCCAATGTCGCGAGCTCCTGTTGGAGGCCATGCGGTATCACTTGGCCCCCGAGCGCCGGTGCGCCCTCTCGACCCCGCGCACGATGGAGAGGAAACCCAAAGGAGCTGAGCCATACCTCTTTGCAGTTGGTGGTGGGTCTCTCTTCGCCATCCACTCCGAATGCGAGGTGTACAACCCCCGGACGGACACGTGGTCCCCAATTTCACCAATGCAGTGGAGAAGGTCCAGATCTGGTGTCACAGGCCTCAGAAAGCTATTGTACGTCGTTGGGGGGTACGATGGTGCTTCCGATCTCGCGACGGCCGAATACTACAACCCCCTGGTCAACAACTGGACGTCGATTACTCCAATGGGGACGAAACGTTCCTGCCTAGGGATTTGCTCGTTCGATGGCTTGATTTACGTTTGCGGGGGGTACGACGGGGCGTCGTGTTTGAGCAGCATGGAACGGTACGACCCCCTAACGGGGGTTTGGTGCAGTTGCCCCGCCATGAATACCAGACGACGGTATTGCAGGATCGCCGTTGTTGACAATTGCGTTTTCGCCCTCGGGGGTTTCGACTCGACCAACTACCAAGCATCAGTAGAAAGATTTGATCCTCGCGTTGGTAATTGGTCGCCTGTACCGTCCATGTCTTCAAGGAGGAGCAGCTGTGGAGTGGCCGCCCTAAACGGCCATTTGTATTGCATTGGAGGCAACGATGGTACCATGTGCATGTCGAGTGGTGAGCGCTTCAACGTAAGGAGAAACGCCTGGGAGCCGATCACGGCGATGCACAACAGACGGGCTACTCATGAGGTGGTGGCCATAGACGGTTCGATCTACGCCCTCGGGGGCAACGACGGTTCTTCGTCGCTCAATTCGGTGGAGAAGTACGACCCGAAGGCCAACAAGTGGATCATCGTGTCGTCCATGGTGACCAGGAGGAGTTCGGTGGGCGCCGCCATCTTGGAATGCATCAACATCGAGCAGGTCCTGAGACGAACGAAGAGTTGA
Protein Sequence
MSSDSGESSDSPPAAASAVLEASTQTPTNEHCDSPMFTPKGYSLKTSGHSSHALTNIFKMRQHGQLCDVTLKVGLETFKAHRVVLASVSPYFFAMFNGEMKEHASSEVVLHDADATAVELLLDYAYTGQIVITADNVQVLLPASSLLQMQEVREACCKFLMKQLHPTNCLGIRSFADTHSCTELHLKSHCYALQNFQQVVATEEFLLLPFAEVEELISNGQLNISSEEDVFTAVLNWLKHDLANRSQYVSNLMEHVRLPLVNRDFLMTRVDNERLVRENSQCRELLLEAMRYHLAPERRCALSTPRTMERKPKGAEPYLFAVGGGSLFAIHSECEVYNPRTDTWSPISPMQWRRSRSGVTGLRKLLYVVGGYDGASDLATAEYYNPLVNNWTSITPMGTKRSCLGICSFDGLIYVCGGYDGASCLSSMERYDPLTGVWCSCPAMNTRRRYCRIAVVDNCVFALGGFDSTNYQASVERFDPRVGNWSPVPSMSSRRSSCGVAALNGHLYCIGGNDGTMCMSSGERFNVRRNAWEPITAMHNRRATHEVVAIDGSIYALGGNDGSSSLNSVEKYDPKANKWIIVSSMVTRRSSVGAAILECINIEQVLRRTKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00466491; iTF_01258178; iTF_00807715; iTF_01295299; iTF_00153602; iTF_00838756; iTF_00151816; iTF_00003860; iTF_00049349; iTF_01371425; iTF_00740932; iTF_00981254; iTF_01252935; iTF_01186345; iTF_01058506; iTF_01126538; iTF_00083979; iTF_00429964; iTF_01400492; iTF_00848429; iTF_00137070; iTF_00627342; iTF_00434288; iTF_00620690; iTF_01120946; iTF_01196850; iTF_01244242; iTF_01059189; iTF_00626299; iTF_01498972; iTF_00070205; iTF_00904190; iTF_00032134; iTF_00030309; iTF_01284841; iTF_01518161; iTF_01240950; iTF_01307329; iTF_01123834; iTF_00308113; iTF_00422757; iTF_00789446; iTF_00399692; iTF_00873162; iTF_01040230; iTF_00029482; iTF_01225936; iTF_00767314; iTF_01039378; iTF_01041010; iTF_00470067; iTF_01104851; iTF_00768891; iTF_01290506; iTF_00249062; iTF_00886566; iTF_01290505; iTF_00166187; iTF_00388812; iTF_00395568; iTF_01014741; iTF_00110682; iTF_00260763; iTF_01013563; iTF_00722205; iTF_01227424; iTF_00903404; iTF_01098639; iTF_00956389; iTF_01097641; iTF_00138172; iTF_01121811; iTF_01216046; iTF_00413633; iTF_01351874; iTF_01369956; iTF_00169644; iTF_00830510; iTF_00387413; iTF_00841939; iTF_00987233; iTF_00349347; iTF_00647303; iTF_00792295; iTF_01047527; iTF_01480231; iTF_01106473; iTF_00056714; iTF_00415210; iTF_00852938; iTF_00026187; iTF_01410092; iTF_00870669; iTF_00929679; iTF_00330832; iTF_00244369; iTF_00735921; iTF_01163281; iTF_00423986; iTF_00911186; iTF_00394643; iTF_01128627; iTF_01329907; iTF_01481011; iTF_01568115; iTF_00753076; iTF_00391989; iTF_00459061; iTF_01366424; iTF_01283513; iTF_01345081; iTF_00639642; iTF_01310682; iTF_01311647; iTF_01566336;
90% Identity
iTF_01258178;
80% Identity
-