Basic Information

Insect: Dorcus hopei
Gene Symbol: BAZ2B
Assembly: GCA_033060865.1
Location: CM065426.1:27300207-27351996[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.4e-17 6.5e-13 49.6 0.0 5 74 670 740 667 743 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.4e-17	6.5e-13	49.6	0.0	5	74	670	740	667	743	0.91

Sequence Information

Coding Sequence: ATGGATAAGGAAAATGGGAAGAGCAGTGAAGGTGGTTCAGGCTCAAGCAAACTTTCCAACCCTCCGGATCCTGCAGCCCTTCTCGATGCTGCCAGTCTTTTCGCTTATTGGCCAAGAAATGATGCAAATTCTGCCAACGCGGCGAACCTGTTCGCAGCGGCCGGTGGCGCCTATGGTCTCAGTCCGCACCCGGCAATGCCTTTTGGTATACTTCCCCCAACACCGACGCGCGGCGTCGCGGCGTATCCACCGGCGTCCAGCGCGGCGGCGGCGTACAACAGCGCCTACACGAATACTCTCTCCGTCGCAGCTAGCCAAGCAGCCAGCCTAGGAATACCAGCAGCGAGTGCAGCATGGTGGTCAATGGCATCACACCTGGCTGCCCAAGATTACCTTGCACGTCTCCAGGCGTCTGGTTTAAACTTCCCGGGCCTGGGAAACCCCGCCGATCCGTACTCGTCGCTGGGCATACCCTCGCTGAGCGCACATCACAAGTCCACGAAGTCCGGCAAAGCTTCGACCGCGTCATCCTCAGCATCCTCACTGCCAAAATTGCAGCAAGCGCAAGGAAATACCTCAAAGGAAAAGTCGTCGTCTTCGTCCTCGTCCTCGTCGTCCTCCTCGTCGGGGGGCTCCAAATCGGACGGCCGCCTCGACCTCAACATCAAGGCCAGTTCGCCCATGCCACATAGCAAGAATTCCAGCGCGAAGTACTCCAACGTCGGCGGCCTGACCATCCATCCCTCGAACATGAAATTGCCCATCTCTTCTGCGAGCGCTGCGAACGCCAGTAGTGAGAAAAAGACGCTCAAATCCAACGACGCCAGTTACTTGAAAAGCTTGGATAAGCCCAAGTGCACGCAGTCTTCTTCTAGCATTTTCACCAGTCCACTCAGCATGGCCAGTAACATCGACAAAACCATGGTCAGTACTTCATCGACGACGCAATGCTCCAGCACCACAGTACCGAGCATACCATCTAGTATTTTAAGTGCTGCTTTAGAAGGGAACGGtgaTCCAAACTCGATCCTCGGCGGAGTCAGATTGCCGCCGGATACGGAAATTATCAAGTACACCTCGTCGATCGTCGGGCCGAAAATACCAGGGACGACGAACCGTGGCCGGAAGAAAACCATTTCGCTGGATCCGCCTTGCGTCAGCGTACATCCGACGCATTCCAGTACGGGAATGCTCATAGAGAGGACCAGTAAACGTCCAAAACTGGATCCCATAGAGATGGGCGCATCGAGTCCACCGAACGACAGGGTGGAAGTCATCAAACTGCCTGCGACCAACGGCAGCCCTTCAGGAATCTCAATACCGTCTTTGGCCGGCAACAGCAGTGGCGAAGCATCCAGCGACGGCCCCCTCAATCTATCCCTCAAGCCGAACTCGAGCTCAGTGAATCACACCAGCTCTTCTCTTAACTCGTTAAGCAACATGTCTGCGAATATCGGAATCGAAAGGATCTCTCGAAGAAAGCCGGGCCCGAAACCTCGCAAAGTGGTTCAGTCTTCTTCGTCTTTGCCTCCGGGTGCACCGAGTGCTTCTCTCGTGCAATTATTTGCAACGGCTGACTCACCGAGGCCTCCCAGTCGAAACGACGGCTTAGAGAATCTAAGCTCGAGTCAGAACCACAAAGACGGAAGGCCAAGAAATTTAGGCCGTGGCGTAAGCAAACCCAAAAAGAACACGGTCGCTTCACTCCTCGCACAAAGCAGAGCTTTAGGTATTAAGCCAATGCCAATATTGGACCCTAATGTTCCAATGACTCAACAGATGTCGCTGCTGAAATCGAACATTTTGGCCGCCCAACAGTACATAGCGGAATCAGGTGGTgatgaaaaaacattaaataaatttttgcaggAAAAATTCAGGGGTACCTTAAGTGACTCAAGCACAGTTGATGCTTCAACAGATTCTGATAACCTTACAGATTCTAATCACACAGATTCCGAGTTGGAAACCGAGATCGTCGCCAAAAAACCTAAGCAGTACGACGAGCAGGCGTTGAGGTTACCTCTGGAAAAAGGTTGGAAGCGAGAGACAGTGATCAGGGGGGTGTCGAAGAACGGCGGCATTAAAGGTGACGTTACTTACGCGGCGCCCGACTCCAGCAACAAGTTCAAGCAGATGTCGGACGTGACGCAGTATTTAGACTATCAAAAGACTAGCGAGCTCAGCCGGGAGAACTTCACGTTTAGCAGTAGGATAATTTTAGGAGATTACCTTCAGCCGATGCTCACCGAGTTCGGGGCCGAGGCGGAAGTCGTTAGACTCACGGAGGACGACGTGCAACGAAGGCTTGAGGATATCAAGGCAGCAATGCGAACTAGTTTGCCAGTGGAACAAAGGATTGAGGTGGCTCGAAGGCAGCAGGCTGCGAGAGCCGCAGCTCGGTTAGACAGGGAGCAGGCGAGGATAGCGAGGGAAATCGAGAAGTCGGAAAGGCAGGAAGCCGCTAGGCGTGACAGGGAAGCAAGATCGCAGCAGATGCTGGAGGGCCGAAAACGTCTAGCGTTCACTTTAGAGCAGAAAGTACAGATAATAACTGAGATAGAAGGTGGCAAGACGAAATCTGACGTGTCTAGAAAGCTGGGCTTGGCCAGTTCGACTGTGGCGACAATCTGGAAGAACCGTAACCACATTATTCACGCGTACGGTTCTGAGAGTGTTGCCTGCAAAAGCCCACCCGTTTCAGATTACGATAcatatgtaaaaaataactttgataGTTCCGTGTCGGGTTCGGATAGCTTTATGGCCAAAAGAAAAAGGCAGGAGGAGATGGAGAAACACAAACAGGAAGAGCAGCAACGCAAGCAACAGGAGAGGGAACTGAAAAGGCAGCAGAACGCGATCTTGAAAGAACAGATGTACATACAGGAGATCAGTAAACAGCGAGAAATGCTCTACACTGTCGAATTGGAGAGAGAGCGAAGAAGACAGCACATGTCACTAGTCAAGGCGCTGGAGAATCGGCGGAAACTGGAGGAGCGCGAGCGCAAGAAGCAGCAGATGCTGGCCGAGAAGCAGGCCAACAAAGAGAAGAAGCTGGAGCAGAGGCGAATGGAAATGGAGATACTGGCGGAGCTGAGGAAGCCCTGCGAGGACCTCGAGTTGGCCCAAAAGCCCCTGCCCGAGTTGAATAGAATTCCGGGGTTGAAACTGCCGGGGAATGCCTTCTCCGATATACTCATGGTGTTTGAGTTTTTGCACAACTTCGGGGAGACTTTAGGTTTCGACATGGAGAGCCTGCCCACGTTGGACTCCCTGCAGCAAGCCCTGCTGCATAACGAGACGACCTCGGAGGCCGAAGAGGAGTTACTCTCGGTCATGACGCACCTAATAGTTTGCGCAATCGAAGACCCCGGCATTCCGAACCCGGCGAGGCACACCACGGTCCTGGGGCAGAGCCTGAGACAGGCGGACATCACCCACACCAACCTCTCGGAGATTCTGCGCATTTATCTGTACGCCAACGCGACGGGGGAAGTCAAAGCTTTGACCGgCGTCCATTTTGAAAGAGATCGAGAGAAACGAGTGGCCGATCACCACCAGAACAATTGCGAAATGCAGCAGACGCAGTCGGGGAAGAACTCGACCTACTACGAGCTCCTGCACGAGAACGCAACGTGGAAAATGTCGGACATGCTGAAGGACAAGCCGTTCCTGGCCCTCTCAGCCACCGATAAGGCAGCGATCCTGGCCTTCATATGCAACGAGCTGCTTCAAAACAAGGCGGTCATCAGGCAAATTGAAAACTCCCTCGAGACCGTGACTCAGTGCAAGAAAGAAAAGTGGATGTTGGATGCCAAGATAAGAAAGTTGAGGATATTGCACAGCCGTAAGGTGAGATCGGAAGCCGCAGAGAAGGCCCACGCGAAGCTCGATGGTGAGACCGGGGAGGCCACCGTCGATTCCCCCGCCATAATCCACCACAAGGACGACCTCCTGGACGATGAGGAGAATGAGATGAGCGAGAACGAAAGCGTCGGGACGCAACCGGAAGAGGAGGAAGACAATAAGTTATCCGGGGAAGAACTGGGCAAGAAGCTGGAGAAATTCATGAAGTCTTCGGAAATCCAACTGCACTCGTTGAACGCGTCGGTCCATCAACTGCGCGCCACCTGTTACGGCCAGGATCGTTACTGGAGGAGGTACTGGTCGCTGCCGAAGGCCGGGGGGGTCTTCGTCGAGGCGATGGAGTCCGCCCAGCCGGATGTTATAGAAGAGCAAGAGGCAGCCGACAAGGCGAGCAACCTGGGCATAAAAAGCATAGACGACATCAAACGCATCATACACGACGTCGACGCGTTGCACGACCCCAACACCGACAAGGAGGTCTCCAACATCGTCGGGATCGAAGAGCCCAGCGAAGAGATCCTCTACAAAGACAATAACGCCAACGAGCGCAACAGCAAGTACACGACGAGCACCAATCGTTTGGGCGTGATAGAAAACGGCGAGATCATGATGGACAGTCGCGAGCGTAACCTGGACGAGCTCAGGAAGAGCGTGGATAGGATAGTACAAAGCCTGGAGAATTCCGAAAACAAAAAGCAGGACGATGTCTTGAATAACCACATCGATTCTCCGCTGATCAAAAAGGAGCAAAGCGAAAGCGAGCTCATCTCGAACAAAAAGTTCAACCTCTTCGAGAAGCTGGGGGAATGCATGGAGCGAGAGAACAAGAGCGAGGAGGACCTCAAGGCGGAAGTCAAGGCCGAAGTTAAGGAAGAGCTGAAGAACGAGATCCTCAACGAGCTCAAGAACGACATTAAGAACAGCTGCGAGGATGAGAAGGGCGATTTCGAGAGGAAGTGGTTCAGTATACTGCCGAAGGATGGGGCCACTTGCGAGGGGGTCCACTTGACTGCTGGGAATCGCTGGGACAACGGAGTGGGGGCTTGCACCCGTGATAATCTCACCGAGCTGAGGATTCCTGTGTTTCCCCCCCCGAATTGCACCTCGTCCGGTTACTTATCGAACAACTGCGATAGCCCTGCGCCTTTACAGATGACTGCGGAAGAGAGTGCGCAGCTCGAGTACATCAAGATACACGGCCTGCCTAAATCGTGTGAGCGAACAACGGTGCCTGCGGATAAAAGATTCGGGTGGTGGAGGATCACGGACACGGAGCAACTGCAACAGCTTCTAGAAGCCTTGCACGTTCGGGGCGCGAGGGAAAGGGAACTTAAGCGCAGCTTTGTCACGTTGATGCAGACGATGTACGAAGACCAGGGGAAGTTGCACATCGAGGAGGGGCAGAAGGATGCCACGGATTTGACGGTGACTGAGAACGATGCTGAGGAATTGGCTGAAGCGAGTGCCAACACTTGGAGCTCGGCTGTTGCGCAACGCGTGGACCTTTTTCTTTTGGAACAGGTCGAAGCCCTTGAAGATAAAGTGGCGAATGCCAGCATGCAAGTTAAAGGCTGGCGCGTGCCTAGTCGTGATGGGGTAGACATCCCCCCCGGTGATGTCGTCAACATTGCTAAAGAACGACTGGCCTCTTTGGAAGCGGCCATCGAAAGGCGATACCTGAAACCCCCTTTAGGAGCCAGCACCGGAGACCCAAATTTAGCAGCGATAGCTCAGGAAGCGACGGGCGTCCCAGTGACTGCCCAGCCCGTCACAAATTTCGATGAGGTTCCTAAAGGCCTGACCGTATGGCGGGAGGCCATAAACAGATCACAGACGTCTGCACAGCTCGCGATGTGCCTGTACACACTGGAGGCTTCCATCGCTTGGGACAAGAGTATAATGAAAGCTGTGAGCCCCTCTCTTGTCTTTAATAAACAGAGAGCTCGCAAATATAACAGCAAGCTGAGTAATTGCCAGTTTTGCAACAGCGGCGACAACGAGGACAAGCTCTTGCTGTGCGACAGCTGCGACAAGGGCTACCACACTTACTGTTTCAAGCCGAAAATGGAGAACATCCCCGACGGCGACTGGTACTGTCACGAGTGCATGAACAAGGCCACGGGCGAGCGAAACTGCATAGTCTGCGGGAAGAAAATGTCCAACACCGGCACGAAACTCATCCTCTGCGAGGTCTGCCCGCGTGCTTACCACACGGACTGCATAAGACCTGTACTTAATAAAATCCCCCGGGGGAAGTGGTACTGTTCGAATTGCATCTCGAAGAAACCACAGAAGAGGACGGTGCGCAAGAACTACAAAAAGCATACGTGCGACAGCGAATCATCAGATCACCATCCGGCAAGTCCTGCGCCCTCTCATAGTTCGGTGACAACGAACGAGGATGCCCCATCGAACGCCTGCAATCAGAGCGACGTCTCGAATTCGAGCTTGCCGAATTCCGGCTCTCCTTCCACGCAGGCGGCCAAAAAGGACCGCATAAATAAGAAACTGATTAAAGAGCTGGCGCCCTGCAAGGCCATCCTGGAGGACCTCGAGTGTCACGACGACGCCTGGCCCTTCCTGTTGCCTGTCAACACGAAACAGTTTCCTACTTACAAGAAGATCATCAAGAACCCCATGGATTTGTCTACTATAAAGAAGCGCCTTCAGGATTTGTATTATAAATCGAAAGAGGAATTCTGCATGGACGTCCGACAAATTTTCAACAACTGCGAGACCTTCAACGAGGACGACAGTCCGGTCGGTAAGGCGGGTCACTGCATGCGTCAGTTCTTCGAAGCCAGGTGGAACGAGTTGTGCATGTCCCACAGTTGA
Protein Sequence: MDKENGKSSEGGSGSSKLSNPPDPAALLDAASLFAYWPRNDANSANAANLFAAAGGAYGLSPHPAMPFGILPPTPTRGVAAYPPASSAAAAYNSAYTNTLSVAASQAASLGIPAASAAWWSMASHLAAQDYLARLQASGLNFPGLGNPADPYSSLGIPSLSAHHKSTKSGKASTASSSASSLPKLQQAQGNTSKEKSSSSSSSSSSSSSGGSKSDGRLDLNIKASSPMPHSKNSSAKYSNVGGLTIHPSNMKLPISSASAANASSEKKTLKSNDASYLKSLDKPKCTQSSSSIFTSPLSMASNIDKTMVSTSSTTQCSSTTVPSIPSSILSAALEGNGDPNSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPCVSVHPTHSSTGMLIERTSKRPKLDPIEMGASSPPNDRVEVIKLPATNGSPSGISIPSLAGNSSGEASSDGPLNLSLKPNSSSVNHTSSSLNSLSNMSANIGIERISRRKPGPKPRKVVQSSSSLPPGAPSASLVQLFATADSPRPPSRNDGLENLSSSQNHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPMPILDPNVPMTQQMSLLKSNILAAQQYIAESGGDEKTLNKFLQEKFRGTLSDSSTVDASTDSDNLTDSNHTDSELETEIVAKKPKQYDEQALRLPLEKGWKRETVIRGVSKNGGIKGDVTYAAPDSSNKFKQMSDVTQYLDYQKTSELSRENFTFSSRIILGDYLQPMLTEFGAEAEVVRLTEDDVQRRLEDIKAAMRTSLPVEQRIEVARRQQAARAAARLDREQARIAREIEKSERQEAARRDREARSQQMLEGRKRLAFTLEQKVQIITEIEGGKTKSDVSRKLGLASSTVATIWKNRNHIIHAYGSESVACKSPPVSDYDTYVKNNFDSSVSGSDSFMAKRKRQEEMEKHKQEEQQRKQQERELKRQQNAILKEQMYIQEISKQREMLYTVELERERRRQHMSLVKALENRRKLEERERKKQQMLAEKQANKEKKLEQRRMEMEILAELRKPCEDLELAQKPLPELNRIPGLKLPGNAFSDILMVFEFLHNFGETLGFDMESLPTLDSLQQALLHNETTSEAEEELLSVMTHLIVCAIEDPGIPNPARHTTVLGQSLRQADITHTNLSEILRIYLYANATGEVKALTGVHFERDREKRVADHHQNNCEMQQTQSGKNSTYYELLHENATWKMSDMLKDKPFLALSATDKAAILAFICNELLQNKAVIRQIENSLETVTQCKKEKWMLDAKIRKLRILHSRKVRSEAAEKAHAKLDGETGEATVDSPAIIHHKDDLLDDEENEMSENESVGTQPEEEEDNKLSGEELGKKLEKFMKSSEIQLHSLNASVHQLRATCYGQDRYWRRYWSLPKAGGVFVEAMESAQPDVIEEQEAADKASNLGIKSIDDIKRIIHDVDALHDPNTDKEVSNIVGIEEPSEEILYKDNNANERNSKYTTSTNRLGVIENGEIMMDSRERNLDELRKSVDRIVQSLENSENKKQDDVLNNHIDSPLIKKEQSESELISNKKFNLFEKLGECMERENKSEEDLKAEVKAEVKEELKNEILNELKNDIKNSCEDEKGDFERKWFSILPKDGATCEGVHLTAGNRWDNGVGACTRDNLTELRIPVFPPPNCTSSGYLSNNCDSPAPLQMTAEESAQLEYIKIHGLPKSCERTTVPADKRFGWWRITDTEQLQQLLEALHVRGARERELKRSFVTLMQTMYEDQGKLHIEEGQKDATDLTVTENDAEELAEASANTWSSAVAQRVDLFLLEQVEALEDKVANASMQVKGWRVPSRDGVDIPPGDVVNIAKERLASLEAAIERRYLKPPLGASTGDPNLAAIAQEATGVPVTAQPVTNFDEVPKGLTVWREAINRSQTSAQLAMCLYTLEASIAWDKSIMKAVSPSLVFNKQRARKYNSKLSNCQFCNSGDNEDKLLLCDSCDKGYHTYCFKPKMENIPDGDWYCHECMNKATGERNCIVCGKKMSNTGTKLILCEVCPRAYHTDCIRPVLNKIPRGKWYCSNCISKKPQKRTVRKNYKKHTCDSESSDHHPASPAPSHSSVTTNEDAPSNACNQSDVSNSSLPNSGSPSTQAAKKDRINKKLIKELAPCKAILEDLECHDDAWPFLLPVNTKQFPTYKKIIKNPMDLSTIKKRLQDLYYKSKEEFCMDVRQIFNNCETFNEDDSPVGKAGHCMRQFFEARWNELCMSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00740835; iTF_01258026; iTF_00466199;
90% Identity: iTF_01258026;
80% Identity: -