Basic Information

Insect: Diplazon laetatorius
Gene Symbol: Hr39
Assembly: GCA_963662125.1
Location: OY759155.1:18246195-18258621[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.62 5.5e+03 -3.6 1.8 143 160 27 44 14 67 0.40

2 5 0.22 1.9e+03 -2.1 19.4 33 165 232 361 224 377 0.54

3 5 2 1.8e+04 -9.6 13.7 82 150 410 464 366 501 0.41

4 5 3.7e-08 0.00033 20.2 0.0 1 21 569 589 569 593 0.92

5 5 4.3e-72 3.8e-68 230.8 0.0 91 408 629 937 609 937 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.62	5.5e+03	-3.6	1.8	143	160	27	44	14	67	0.40
2	5	0.22	1.9e+03	-2.1	19.4	33	165	232	361	224	377	0.54
3	5	2	1.8e+04	-9.6	13.7	82	150	410	464	366	501	0.41
4	5	3.7e-08	0.00033	20.2	0.0	1	21	569	589	569	593	0.92
5	5	4.3e-72	3.8e-68	230.8	0.0	91	408	629	937	609	937	0.84

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCACGGAGGGCCCGGGCTGGTGGCCTCCGGCGCAATCGTGGAAGTCATCCACCATCGCATCatccacgtcgtcgtcgtcgtcgtcctcgtcgactTTACCATCGTCCCGCACACTTGAGACTGGAAAAAACGTTTCCGTCACCACGATCAACGTACCGCCGGCTCAGGACATGCACGATGGTAAAAGCGTGTGCAAGTTCCTGGGAGGTCAGAACGGCGTGACCGTGTCGGTTGTCTCGAGTTGCGGAAGCGGTCCTGGTAGCGTAATGGGTACCGGACCAATCAGCGGAGTCGGCGGAGTCGGTGGAACGTCTTCATCGTTACCGGATCCGAGTTCGTACGACGATCTCGAGGACAGCGACGGTGAAGTCAGCAAGATAGACTTTCGGGGTGTCAATCtgcgaacgaagaaaaagcgCGATGGATCAGCAGGCGCAACGGAGAACGACTGCGGTGCTTTGGGCACGGAAAATCTGGAGCAGCAGCAACCCGAGAGACCGATGTCGTGGGAGGGCGAGTTGTCCGATCAGGAAATGTCTTCCAATACCATCACAAATCAGGACCACGAGGAGACCTCGATGGAAGGTGTCCAGGTGTGCGGTGCGAGTCCAGGCCCCGCGGACCAAAAATTTCCGATAAAACCCGAACCGGATTTTCGTTTGAGTCCGAATCAAGCCCAAAATTCCCAAAACGACGTTAACCCCACATTGTCCCACTCCCACCAGCTCCACCATCACCACAACCACCCCCACCAGCATGCCCCCCATCCCCACCCGCAACAGCAGcatcaccagcagcagcaacatcatcatcagcaCCCCCAGCAACGATCAACAGACACAACCGACCAACAGACCCAACAAAACGACCTTCCACTGCTAGTGGGCAAGCTTCTAGGCGGTTACAACAGTTCAACCCCCAATCACAGTCCGATAATGAATCCCCGTCATCATCTGACAAAGCACAGTCATACTAGATCCCAAGTTCCGTCACCGGATTCAGCGATCCATTCGGCATACAGCGTTTTCAGTTCCCCAACCCAAAGTCCACACGCTGCACGTCATTCGGCACTGGGACCCGGAAGTCCGATACCATCGtcgtctctctcactttccCGTCACAGTTTCAACAATTCCACGTCGTCGTTGTCACTGTCATTGTCCCATTCGCTGTCGCGAAACAATTCCGACGCTTCGAGCAGTTGTTACAGTTACGGTTCATTGAGTCCTCCGACTCATTCGCCGGTTCAGCAGCCCAGACACTCTCAGCATcatcaccagcagcagcagcatcagcagcagcagcagcatcaacaCCAGGTGGCGCAGGGTGCGCCTCTGCATCTGCCTCCAACCACGAGTCCGTACTCCAcccaaaattccgaaatttCGGACGCACATCCGGACGATCACGACGATTGCAAGATTCCCACAGCCCCATCTGGCATATCAACCCGCCAACAACTCATAAACAGTCCTTGCCCAATATGCGGTGACAAAATAAGCGGTTTTCATTATGGAATATTTTCCTGCGAATCTTGCAAAGGTTTTTTCAAACGCACAGTGCAAAATCGCAAGAATTACGTTTGTCTGAGAGGCGCAGGGTGTCCAGTGACTGTGGCAACGCGGAAAAAGTGTCCGGCCTGTCGTTTCGACAAGTGTTTGAATATGGGAATGAAGTTGGAGGCGATTAGGGAGGACAGGACTCGGGGAGGTCGTAGCACTTATCAGTGCACTTACACTTTGCCGGCTAATTTGATGGGAGGGGGATCTGGTAGCTTGCCGGGTGATAAAATCATCGGTGGCAATTGCAGTCCGGCTCCCGCGGGTTCCGAGCATCATCATTCGGTTCGTCATCATTGGAATCATTCGCACAAGTTGCAAGCCGTACCGCAATTGCTTCAGGACATAATGGACGTGGAACATCTTTGGCACTACAACGATAATGATCGCACGACCGCTGTTGGGGCACAAAATTCGGGTTCCAATTCCGTTGACGACGCGACCATGTCCAATGACATTGGATTGTCGAATTCCGGTGGAAATTCCACGATCAACAATGGCAacgttgaaattaaaaacgatCCTGGACGTGAGAATTCAGCGACATCTGTCGGCGATGATATTCATCGACATAATACGTCCAACGATAATACGTCCGGTGTCAATAATTCGAATCCCAATGGGAGTTCCACGCAGAATCCggattttttgtcgaatttgtGCAATATAGCGGATCATAGATTGTACAAGATTGTCAAGTGGTGCAAAAGTTTGCCGTTGTTCAAGAATATATCCATTGACGATCAGATATGTTTGTTGATCAATTCTTGGTGCGAATTGTTGCTTTTTTCGTGCTGCTTTCGAAGCATGAGCACGCCCGGGGAGATAAGGGTTTCGTTGGGGAAATCGATTACCTTGGAACAGGCGAGACAGTTGGGATTGGCCACTTGTATCGAGAGAATGCTCGCTTTTACGAATAATCTGAGGAGATTGAGGGTCGATCAGTACGAATACGTCGCGATGAAGGTAATCGTTCTGTTGACTTCGGACACGAGTGAGTTGAAGGAACCCGAAAAAGTCCGAGCCTCCCAAGAAAAAGCTCTTCAAGCGCTTCAGCAATACACGATAGCGAGGTATCCGGAAATGCCAGCTAAATTCGGGGAGTTGCTTCTGCGAATACCGGATCTTCAGAGAACTTGCCAGGCCGGCAAAGAGTTGCTGAGCGCCAAGCGGGCCGAGGGCGAGGGCAGCTCTTTCAATCTTTTGATGGAATTGTTGCGGGGAGATCACTGA
Protein Sequence: MSEQNGPTEGPGWWPPAQSWKSSTIASSTSSSSSSSSTLPSSRTLETGKNVSVTTINVPPAQDMHDGKSVCKFLGGQNGVTVSVVSSCGSGPGSVMGTGPISGVGGVGGTSSSLPDPSSYDDLEDSDGEVSKIDFRGVNLRTKKKRDGSAGATENDCGALGTENLEQQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCGASPGPADQKFPIKPEPDFRLSPNQAQNSQNDVNPTLSHSHQLHHHHNHPHQHAPHPHPQQQHHQQQQHHHQHPQQRSTDTTDQQTQQNDLPLLVGKLLGGYNSSTPNHSPIMNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGPGSPIPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSQHHHQQQQHQQQQQHQHQVAQGAPLHLPPTTSPYSTQNSEISDAHPDDHDDCKIPTAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLMGGGSGSLPGDKIIGGNCSPAPAGSEHHHSVRHHWNHSHKLQAVPQLLQDIMDVEHLWHYNDNDRTTAVGAQNSGSNSVDDATMSNDIGLSNSGGNSTINNGNVEIKNDPGRENSATSVGDDIHRHNTSNDNTSGVNNSNPNGSSTQNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00059522;
90% Identity: iTF_00459857;
80% Identity: iTF_00459857;