Basic Information

Gene Symbol
-
Assembly
GCA_029229535.1
Location
CM055255.1:24061594-24075307[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3e-05 0.0027 18.5 0.7 1 23 158 180 158 180 0.95
2 15 0.0013 0.12 13.3 1.2 3 23 188 208 187 208 0.99
3 15 0.00011 0.01 16.7 0.5 1 23 314 336 314 336 0.98
4 15 0.4 37 5.5 0.2 1 23 343 366 343 366 0.89
5 15 7.1e-07 6.5e-05 23.7 3.6 1 23 392 414 392 414 0.98
6 15 0.012 1.1 10.3 0.0 1 23 427 449 427 449 0.94
7 15 4.2 3.8e+02 2.3 0.1 1 23 455 478 455 478 0.80
8 15 0.057 5.2 8.2 1.9 2 19 486 503 486 504 0.96
9 15 1.9e-05 0.0017 19.2 4.2 1 23 513 535 513 535 0.97
10 15 0.0045 0.41 11.7 0.3 2 23 541 562 540 562 0.97
11 15 9.6e-06 0.00088 20.1 0.4 1 23 570 592 570 592 0.98
12 15 0.0042 0.38 11.8 0.2 3 23 600 620 598 620 0.97
13 15 0.00013 0.012 16.5 0.3 1 23 626 648 626 649 0.95
14 15 0.053 4.9 8.3 2.7 1 23 663 685 663 685 0.96
15 15 0.00046 0.042 14.8 0.1 1 20 1056 1075 1056 1078 0.94

Sequence Information

Coding Sequence
ATGGAAGAATCATTTGACTTAACATGGGAGGATTCATCCACAGTAGTACAAACCGAAGAGGTAATTTGTGGTATAGAAAATGAAATCCTCCCATCGGAAAATGTCGAATTCACTGGAGTTCAAGAAGAGACAGTTACAGATGAAGTTatagaaatacaagaaaaagaggAAGTCATTGAATTACCGGATATACAAGAAACACAGGAAGTACAAGAAAATGTTGATCATGGTATTATGTACCTACCAGATGGTAATATGCTTGTAGTTAATGATCAAGGCAGAAGTGATTATCAAGGACAGATAATGGATTGTCAAGTTTCTGAAGAGATCATTACTGGGGAATGGGGGGAAAGTTGTGCAGAAGAAATTGttgTGGGTTCTGAAGAAGCAGTAGGTACAGAAGACGGTAACCGGGAAGATTTCGATATACCTCTACCGACTGACCAAGACGAATATACAGCAGCCAGACCTTACCCTTGCGATTTTTGCAGTAGGAGATTCAGGAAAAAAGCTAATCTCATGAATCACATGGTGGCACATCAAACTGATAGACCTCACGGTTGCAATTTGTGTGGTGTTCGGTATATAAGAAAATGCGATTTAATGAACCATCTCAAGATTCATGCTTATATACCAGACGCAGACGGTTTAGAAGAACAAAATATTCAACCGATGGACGAAATGGATGATAAtacagataaaaagaaaaaaactaaacagattaagaaaaagaagaaaatcaaaGAGGAATATGATCAATACGAAGATGATTTAGggGCGTCCAGTTCTCGCGGTTACAATTACGTCGAAGAAGACGTAAAACTGATGGAACAAATGTCTAATAACATAAAACACGATTACGATTATAtacacgaagaagaagaagaagtgcAACAACCTAGTGAATCCCGTTACCCCATTACGGATCCTAGAAAACCGTTCGTTTGTCAACATTGCGGCGTAGGATTCGCTAGAGAGAAAGCCATGATGTCCCATCTTAGGATGCATTCGGAAGGCGACAGTCCTTTCGAATGTCAAAGATGCGGCGAGATGTTTTGGGACTTGATTCAAATGAAGGAACACGCCAAAGAGAAACACGGCGACGTCGAAGGCTTCGATGACGACGAAGACGACGACGACGATTATTCCGAAGAGGATACCAAATACGGAACGTATTATTGTTCGACGTGCGGCTTATCATTTCACAGACAAGATAATCTTCGTAGACATCAAAGGATACACGTCAAAGAGGAATTCGTCAACGAACATGAATTCGGTCACATCTGCAACGTGTGCGGGGAATCCTTTCAGGAAGCTTTGGATTTGTTGGCGCACGCCGAAGTACACGCCAGGACACTCGAGTATAGGTGTATGATTTGCGGAGAATTGGCAGAGGATGAGCACGTTTTGGCGGTTCACGTACAGgctAAACACGGTAAAAATCTACCGCCAAATACTTGTATGTTGTGCGGAAGGTCCTGCAAAGACCGTAGGACCTTACTTAAACACTCCTGGGAACATTCTAAAGAAAAGatATTCGCTTGTACGAAATGCGACaaaacttttcataataaagCTCGATTGAAACGTCACATGTTATCGCACAGAAACAAAGTGGTAACGTGCGACGTGTGCGGCGAAGATTTCCCCGACGGTCGTTCGTTGATGAATCACCGACACAGTCACAGCAACGTTTCCGGTAGGCAATTTCCTTGCAGGGAATGCGGTAAAACGTTCGGTTCGAGAAGTTCCCAACAAATACACATCAGAATACATACGGGCGAACGACCGTACGGTTGTAGATTTTGTTGGAAAGCTTTCGCCGATGGCGGTACGTTACGCAAACACGAACGCATACATACTGGCGAGAAACCGTACGCGTGCGCCGTTTGTCCTCGAGCTTTTAATCAACGCGTCGTATTAAGGGAACACATAAGATCCCATCATTCCGGTCCCGATCCGAAATATTCCAATAGTATGACGCCGTATTGTTGTTCGGTTTGTTCGGATATGTTCACCACTTCGCAAGATTTGATATTACATTTGATACATCATTGCGATATGAATACAGCGATGAAACGTCAACCTCAAATCGGTCCTAGGAAATATAAAAGGAGAAGGAAATTGAAACCGCACGAATTGGAATTGATAACTAGAGTTGAAGAAGGGGATAACGATCAGTCAGAAGATTTAGGCGATAATTATACCGATTCGGAAgaggaaaaagaaagaaaaagaagatatataagaaaacaacAGCCGACGAAAAAGTCGCAATCGCCGGAATCTTCGAAAGAAATAGTTCCTGATACTTACGCCGAATTATATAATAGCGTTTCGTCGACCATAGaaaatatcaattctTTGGTAAATTCGAAATCGTCAACACCGAAGGCGAAACAGcaaatgaagaaattgaaaacagATCAATCGATACCGAGCCGACCGAAAATGATACACACGCAAAAGACGCGCGTGCCAGTTGAAGCCGGCGAAGACGGTCGCGTAAGACACAAGACGAAAACTCTAATCACCAGAACCCAACCGGCGGAAATAAAATCGGCTACTGgTGAACGTATTCGTCCCCGAACGAAAAACGTCAACTATCACGTTCTGCAAGAGAAATTTCCCGTCGCGACGTTCGCCGACGTCGCCACCGATAAAGATACCACCCAAGAAGCCGTCGATAATCTATTGAAACAAGAAAACGTTATAGTCCAACCGGAACACGTTATAGAGGAAACCGCAACGCCGCAACACAATAACGGAGTCATATACATGGATCAATTCGAACATCCGACAGAAGTCGGCGCCGAACAGACCGTCGAAAGCGAAACGGTTCCGCCTCCACCGGTCGCACAGGAACCGGAAAGATTTTACGAAATACGGAGAGTAACGACGAGATCGAGGAGTGGGAATCTTGGTAACAGTAATAGTTTGAAACCGGGTAGGCACGTCATCGGACCCGGAAGTAAAGTGAGACTCGTCAAAGAAGGTATGATAGTATCGAAGGCTCGTAACAAAAAATCCGAATCGGAAAACGAATCGCCGGCGGATCAGATCCAATTACAACAACCGGTGAAACAAGAAATATTAGATCCGAGTCCGTTGCACGAATTGGCCGAAATATCGATGCAACACGCCAACGCGACTTCGCAGAGTCTTTTTAAATGCGAAATGTGTAGCGAAGTGTTTACAGATAGGGCTCAATTACTCGTCCACGTACCGATACACATTTGA
Protein Sequence
MEESFDLTWEDSSTVVQTEEVICGIENEILPSENVEFTGVQEETVTDEVIEIQEKEEVIELPDIQETQEVQENVDHGIMYLPDGNMLVVNDQGRSDYQGQIMDCQVSEEIITGEWGESCAEEIVVGSEEAVGTEDGNREDFDIPLPTDQDEYTAARPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGVRYIRKCDLMNHLKIHAYIPDADGLEEQNIQPMDEMDDNTDKKKKTKQIKKKKKIKEEYDQYEDDLGASSSRGYNYVEEDVKLMEQMSNNIKHDYDYIHEEEEEVQQPSESRYPITDPRKPFVCQHCGVGFAREKAMMSHLRMHSEGDSPFECQRCGEMFWDLIQMKEHAKEKHGDVEGFDDDEDDDDDYSEEDTKYGTYYCSTCGLSFHRQDNLRRHQRIHVKEEFVNEHEFGHICNVCGESFQEALDLLAHAEVHARTLEYRCMICGELAEDEHVLAVHVQAKHGKNLPPNTCMLCGRSCKDRRTLLKHSWEHSKEKIFACTKCDKTFHNKARLKRHMLSHRNKVVTCDVCGEDFPDGRSLMNHRHSHSNVSGRQFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACAVCPRAFNQRVVLREHIRSHHSGPDPKYSNSMTPYCCSVCSDMFTTSQDLILHLIHHCDMNTAMKRQPQIGPRKYKRRRKLKPHELELITRVEEGDNDQSEDLGDNYTDSEEEKERKRRYIRKQQPTKKSQSPESSKEIVPDTYAELYNSVSSTIENINSLVNSKSSTPKAKQQMKKLKTDQSIPSRPKMIHTQKTRVPVEAGEDGRVRHKTKTLITRTQPAEIKSATGERIRPRTKNVNYHVLQEKFPVATFADVATDKDTTQEAVDNLLKQENVIVQPEHVIEETATPQHNNGVIYMDQFEHPTEVGAEQTVESETVPPPPVAQEPERFYEIRRVTTRSRSGNLGNSNSLKPGRHVIGPGSKVRLVKEGMIVSKARNKKSESENESPADQIQLQQPVKQEILDPSPLHELAEISMQHANATSQSLFKCEMCSEVFTDRAQLLVHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01047655;
90% Identity
-
80% Identity
-