Basic Information

Insect: Dione vanillae
Gene Symbol: Hr39
Assembly: GCA_037178615.1
Location: JAZFAU010000030.1:43331-52970[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 3.7e+04 -5.7 11.8 34 192 139 333 123 360 0.53

2 3 3.1e-08 0.00057 20.4 0.1 1 20 437 456 437 464 0.91

3 3 3.7e-66 6.9e-62 211.2 0.0 138 408 476 755 462 755 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	3.7e+04	-5.7	11.8	34	192	139	333	123	360	0.53
2	3	3.1e-08	0.00057	20.4	0.1	1	20	437	456	437	464	0.91
3	3	3.7e-66	6.9e-62	211.2	0.0	138	408	476	755	462	755	0.84

Sequence Information

Coding Sequence: ATGAATACCGCGATGTCGAATGAGGTAGAGCCAGTGAAGGTGGAATGCGGTCACGTCTCTGTTACTATTTTCAGCATGTCAGGTCCAGAGACTAGCAATGGACAATTCTCGTACAGTTCGAGCGGGGTGCGCATCAGTGTTTCTTCGGTACCACAGGACGAAGATTCAACTGATGCTGAAATCTCTAAGATTGACTTTACACAACACCAGTATGAGGTtaatatgagaaataaaaagaaacgttCTGCAAGCGGTCAGTGCGAACAAACCAATGAACAAGAACGGCCGATGTCGTGGGAAGGAGAGCTTTCTGACTCTGAAATGGTTATCGATACTAGTGTTAATAATGATGAAAACAGTAGTTCTCTTGACTTACAATCGTCCCGGGATTCTATCGACACACTTCGCAACGTCACTATCAAGACGGAAACAGTCAAAGCTGAAGCTTTCCAAAGCTTAGACGACCAGCGAGTGTTGGATCTTAAATATGCAGCTTTACAGTCGCATCAGAGGAGTCTAAGTATGAATAGGATACCAGTGCTAACAGAGACATCACTATCACTAGCGAGACGACCCTCCTCACCAACGAGTAGTGCCAAATCACTACACTCAGACTATGAAACACAGCTTATGCAAAACCCCGCCATCGAAGTACAgaatttaactattaaaaagGAAACTCAGTTATCTGAATTAAAATGCGAACCAACAGGAGGTATGGACAAACTATTAGGACTACATGGGTCGCCGTTATTGGGGCGGTTGCCCAGGGTTCAATCCAGTGCCAGTACAGATTCTGCGGTTCACTCTATGTATACTCATAGCGTATACAGCAGTCCTTCGGCAAGTCCTCGTCCATCACGACACTACACGCCATCTCTGTCGAGAAACAATAGTGATGCATCACATTCCTCCTGCTATTCCTATAGTTCAGAGTTTTCGCCTACACATTCTCCAGTACAGagTCGACATCCCCACGTGGTGTACCGCGAGACCGCCGTTTATCCAGCCTCACCTGCCCACGACGAAGATACGGATGCTGCGGATGAACGACTTCATCATCATCAAGGGATTAGTAGGCAACAGCTTATTAATAGtCCTTGTCCCATATGCGGTGACAAAATAAGCGGTTTTCACTATGGCATATTCTCTTGTGAGTCTTGCAAAGGGTTCTTCAAAAGAACAGTACAGAATCGCAAAAACTACATGTGTCTTAGAGGCGGCAATTGTCCAGTAACTGTAGCGACAAGAAAAAAGTGCCCCGCGTGTAGATTTGACAAGTGCTTAGGATGTGGGATGAAACTGGAAGCAATAAGAGAAGACAGGACCCGAGGCGGCCGCTCCACATACCAATGCTCGTACACGCTGTCGGGCGCGTCGTCGACCGGCTCGCTGCTGTCCGCGCACGCGTCGCCCACCTTACGACACGCTTCCAGTCTTACTTCTGTAAATGGTCCCGCTTCTTACAACAGTCGAGGGGAATCGAGTAACAGCCGACTCACGCCCGATATACCGCCGTTATTGCAGGAAATAATGGACGTGGAACACTTATGGCAATACAACGAGTCGGAATTGAGTAGAATGAGTAAATCCACTGGTAGCCCCTCAGCGAACCCACTGTTGGCAGCCAGTGGCATCACTGCGCAGAACTCCAGCGCAGATTTCTTAGCAGATTTATGTAACATTGCTGACCATAGACTTTATAAGATAGTCAAATGGTGTAAGAGTTTGCCGCTGTTTAAGAACATTTCTATCGACGACCAAATCTGCCTACTAATAAACAGCTGGTGCGAGTTGCTCGTGCTGTCGTGTTGCTACCGGGGCGTCAGCACGCCGGGGGAGGTGCGCGTTGGTGGAGGACGCGGTATTACTTTACATCAAAGTGCCAAGTACGGTTTAACGCCGTGTATAGAACGAATGCTGAGTTTCACTGATCACTTGCGAAGACTGCGAGTGGACCGATACGAATATGTTGCTTTGAAAGTCATCGTGCTTCTCACTTCTgatgccCCAGAACTTCGTGAAGCAGAAAAAGTGAGAGCGTCTCAGGAAAAAGCGCTTGCAGCGCTTCAAGCGTACACCGCAACGCATTCGCCGGACACTCCTGCTAAATTTGGCGAATTGTTATTACGTATTCCTGAATTACAAAGGACTTGCCAGTTTTTCATGCAAGTCGGTAAAGAGATGCTGAACCCGGCAAACAAGAGCAAAGATGGCGACGGTCCCAGCTTCAATCTCCTCATGGAACTACTTAGAGGCGACCATTGA
Protein Sequence: MNTAMSNEVEPVKVECGHVSVTIFSMSGPETSNGQFSYSSSGVRISVSSVPQDEDSTDAEISKIDFTQHQYEVNMRNKKKRSASGQCEQTNEQERPMSWEGELSDSEMVIDTSVNNDENSSSLDLQSSRDSIDTLRNVTIKTETVKAEAFQSLDDQRVLDLKYAALQSHQRSLSMNRIPVLTETSLSLARRPSSPTSSAKSLHSDYETQLMQNPAIEVQNLTIKKETQLSELKCEPTGGMDKLLGLHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPSRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHVVYRETAVYPASPAHDEDTDAADERLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGASSTGSLLSAHASPTLRHASSLTSVNGPASYNSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELSRMSKSTGSPSANPLLAASGITAQNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKYGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTATHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00642460;
90% Identity: iTF_01018623;
80% Identity: iTF_00458147;