Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.32 9.4e+03 -0.6 0.0 26 44 46 64 41 68 0.81

2 5 5e-05 1.4 11.7 0.4 23 46 71 94 56 96 0.88

3 5 3.2e-06 0.093 15.5 0.0 21 48 97 123 93 126 0.89

4 5 0.0045 1.3e+02 5.4 0.1 21 47 125 151 123 156 0.90

5 5 0.016 4.6e+02 3.6 0.0 26 44 158 176 151 181 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.32	9.4e+03	-0.6	0.0	26	44	46	64	41	68	0.81
2	5	5e-05	1.4	11.7	0.4	23	46	71	94	56	96	0.88
3	5	3.2e-06	0.093	15.5	0.0	21	48	97	123	93	126	0.89
4	5	0.0045	1.3e+02	5.4	0.1	21	47	125	151	123	156	0.90
5	5	0.016	4.6e+02	3.6	0.0	26	44	158	176	151	181	0.87

Coding Sequence: ATGGATGAGGACAAAGCGAGAGAATTAAAACCAGTTTACTCCTGCCGGAGATGCAAAATTaattttgataCAAAACGTGAGTCTTTGCTTCACCGGAAAACTGTCCACGAAACTAATCCAGATGAATATAAATATGTGTGCGAAATATGCAACAAAGGATTTGCAAATCCTGGAAATATGTATCGCCACATAAAGGGTCACAGCGATGTAAGGCCACATTCTTGTAAGATCTGTGGGAGATCCTTTGCACAAGCGGCTAATTTACAAAGGCATTTATCCATTCACAATGGAGAAAGGCCATTCACTTGCTTAATATGTGACAAAGGCTTCACACAACAAGGGAATTTGAGAAGACATGAACTAACCCATACTGGAGAAAAGCCATTCCGATGCAAGAGATGTGGACGAATGTTTTCACAACGAGTAAATTTAAAGAAACATGTGATGCTGCATCAAGGATATAAACGCTTTAGCTGTGACATTTGCAACAAATCCTTTTTGCAAGTACAAAACTTTAAGAAGCACATGAGCAAGCATGAGAATACATATAAAACCGAAAAGACCGAACTatTCTATGAATGTGCTTTGTGTAGAGTAATATTTGCAAATCTGGAAGAATTCCAATCCCATGAAATATTCTGTGAAGTTGCTGGAGAAGAACAAATTGAAACCACTGAAATCACCACTGAAATTGTTGAAACTACATAG
Protein Sequence: MDEDKARELKPVYSCRRCKINFDTKRESLLHRKTVHETNPDEYKYVCEICNKGFANPGNMYRHIKGHSDVRPHSCKICGRSFAQAANLQRHLSIHNGERPFTCLICDKGFTQQGNLRRHELTHTGEKPFRCKRCGRMFSQRVNLKKHVMLHQGYKRFSCDICNKSFLQVQNFKKHMSKHENTYKTEKTELFYECALCRVIFANLEEFQSHEIFCEVAGEEQIETTEITTEIVETT

Sequence clustering based on sequence similarity using MMseqs2