Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.35 1e+04 -0.7 0.0 26 44 61 79 56 83 0.81

2 5 5.5e-05 1.6 11.5 0.4 23 46 86 109 71 111 0.88

3 5 3.9e-06 0.11 15.2 0.0 21 48 112 138 108 140 0.89

4 5 0.0049 1.5e+02 5.3 0.1 21 47 140 166 138 171 0.90

5 5 0.017 5.2e+02 3.5 0.0 26 44 173 191 166 196 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.35	1e+04	-0.7	0.0	26	44	61	79	56	83	0.81
2	5	5.5e-05	1.6	11.5	0.4	23	46	86	109	71	111	0.88
3	5	3.9e-06	0.11	15.2	0.0	21	48	112	138	108	140	0.89
4	5	0.0049	1.5e+02	5.3	0.1	21	47	140	166	138	171	0.90
5	5	0.017	5.2e+02	3.5	0.0	26	44	173	191	166	196	0.87

Coding Sequence: ATGGCATCAGCTTACCCCTTAAAGAATTTCGTTGCCCACATACAATTGGTTTCAATATATCTTAATAGCTTGTTAAGTGATGGTAGTATTTTGTATTATGTAAGGaattttgaTACAAAACGTGAGTCTTTGCTTCACCGGAAAACTGTCCACGAAACTAATCCAGATGAATATAAATATGTGTGCGAAATATGCAACAAAGGATTTGCAAATCCTGGAAATATGTATCGGCACATAAAGGGTCACAGTGATGTCAGGCCACATTCTTGTAAGATCTGTGGGAGATCCTTTGCACAAGCGGCTAATTTACAAAGGCATTTATCCATTCACAATGGAGAAAGGCCATTTACTTGCTTAATATGTGACAAAGGCTTCACACAACAAGGAAATTTGAGAAGACATGAACTAACCCATACTGGAGAAAAACCATTCCGATGCAAGAGATGTGGACGAATGTTCTCACAACGAGTAAACTTAAAGAAACATGTAATGCTGCATCAAGGATATAAACGCTTTAGCTGTGACATTTGCAACAAATCTTTTTTGCAAGTACAAAACTTTAAGAAGCACATGAGCAAGCATGAGAATACATATAAAACCGAAAAGACCGAACTaTACTATGAATGTGCTTTGTGTAGAGTAATATTTGCAAATCTGGAAGAATTCCAATCTCATGAAATATTCTGCGAAGTTGCTGGAGAAGAACAAATTGAAACCACTGAAATCGCCACTGAAATTGTTGAAACTACATAG
Protein Sequence: MASAYPLKNFVAHIQLVSIYLNSLLSDGSILYYVRNFDTKRESLLHRKTVHETNPDEYKYVCEICNKGFANPGNMYRHIKGHSDVRPHSCKICGRSFAQAANLQRHLSIHNGERPFTCLICDKGFTQQGNLRRHELTHTGEKPFRCKRCGRMFSQRVNLKKHVMLHQGYKRFSCDICNKSFLQVQNFKKHMSKHENTYKTEKTELYYECALCRVIFANLEEFQSHEIFCEVAGEEQIETTEIATEIVETT

Sequence clustering based on sequence similarity using MMseqs2