Basic Information

Insect: Diloba caeruleocephala
Gene Symbol: Hr39
Assembly: GCA_947459985.1
Location: OX381607.1:5668518-5699067[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.073 6.4e+02 0.0 3.1 79 192 230 342 167 372 0.60

2 3 4.3e-08 0.00037 20.6 0.1 1 21 445 465 445 478 0.91

3 3 1.1e-64 9.4e-61 207.0 0.0 151 408 497 763 470 763 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.073	6.4e+02	0.0	3.1	79	192	230	342	167	372	0.60
2	3	4.3e-08	0.00037	20.6	0.1	1	21	445	465	445	478	0.91
3	3	1.1e-64	9.4e-61	207.0	0.0	151	408	497	763	470	763	0.84

Sequence Information

Coding Sequence: ATGGTGATGAGTACCGCGATGAACAGTGAGGGCGAAGCGGTGAAGGTGGAGGGGGGACACGTATCTGTCACCACTATCAGCATGTCGGGCCCAGAGACTAGTAACGGTCAGTTCTCGTACAGTTCGAGCGGCGTGCGTATCAGTGTTTCTTCAGAGCCTCATGATGAAGACTCTACTGACGCCGAGATCTCCAAGATCGACTTCAACCAACATCAATACGAGGTCAACATGCGTAATAAGAAGAAGCGTTCATCCAGCGGTGCGCACTGCGAAGTATCCAGCAATGAGCGCGAACGACCCATGTCGTGGGAGGGAGAGCTTTCTGACTCGGACATGGTCATAGACACCAGTGTTATTAACGACGAGAACAGCAGTTCCCTCGACCTCCAATCATCGAGAGACTCGATCGATACTCTCCGCAATGTGAGCATCAAGACGGAGCCTCTTAAAAGCGAGGGCTTCCAGGGCGTGGACGAGCAGCGCGTGCTGGATCTCAAGTACAGCGCACCGCTGCAGCCGCACCAGCGGAGCCTTAGTATGAATAGGATATCAGTGCTAACAGACGGCACCTCACTATCTTTAGCGAGACGACCGTCCTCTCCGACAAACAGTGCCAAGTCCCTCGTACTCAGTGACCAGGTGTCCGCTCTTGTACCACACGCTGGACTCGACCAAGTACATAACCTTACCATCAAGAAGGAGACGCAGTTATCTGAATTGAAATGCGAGCAGTCCGTGGGCATGGACAAGTTGATCGGTGCACTGCACGGGTCGCCGCTGCTGGGGCGGCTGCCGCGCGTGCAGTCCAGCGCCAGCACCGACTCCGCCGTGCACTCCATGTACACGCACAGCGTGTACAGCAGTCCGTCGGCGAGTCCTCGCGCGTCGCGGCACTACACGCCGTCGCTGTCGCGAAACAATAGCGACGCTTCGCACTCCTCCTGCTACTCGTACAGCTCAGAGTTCTCGCCCACGCACTCGCCAGTACAGGGCCGTCACCCCCACGTGATGTACCGCGAAGCGGCGGTGGCGTACGACGGAACACACGATGACGAGACCGACGCGCCTGAAGACAGGCTGCATCATCATCAGGGTATCAGCAGACAGCAGCTTATCAATAGCCCATGTCCGATATGTGGTGACAAGATCAGCGGGTTCCACTACGGGATCTTCTCGTGTGAGTCCTGCAAGGGTTTCTTCAAGCGGACGGTGCAGAACCGCAAGAACTACATGTGCTTGAGGGGGGGCAACTGTCCAGTAACCGTTACCACGAGGAAGAAGTGTCCCGCGTGTCGGTTCGACAAGTGTTTAGGATGCGGGATGAAGCTTGAAGCTATAAGAGAGGACAGAACTCGAGGCGGTCGTTCCACCTACCAGTGCTCGTACACATTATCCGGCGCCGCGTCAACCGGCTCCCTGCTGTCTGCGCACGCGCCTACTACGCTGCGGCACGCCTCCAGCCTCACTTGTGTAAATGGTCCTGGGTCATATAGCAGCCGAGGGGAGTCCAGCAACAGTCAAGTAACGCCAGATATACCGGCATTATTGCAGGAAATAATGGATGTGGAACATCTCTGGCAATACAACGAGTCTGAACTGAGCAGGCTGGGCAAATCAACCGGCAGTCCATCTGCCAACCCCCTGTTGGCCGCCAGCGGGATTACCGCTCACAACTCCAGCCCCGACTTCTTGGCAGACCTGTGTAATATTGCCGACCATCGGCTGTACAAGATTGTCAAGTGGTGCAAAAGCTTGCCACTCTTTAAGAATATTTCGATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGTTGCTACCGCGGCGTGAGCACACCCGGCGAGGTGCGCGTGGGAGGCGGACGCGGCATCACGCTGCACCAGAGCGCTAAGTTGGGGTTGACGCCGTGTATAGAACGCATGCTCAGTTTCACCGACCACTTGAGAAGATTGCGGGTGGACCGATACGAATACGTAGCGCTCAAGGTCATCGTACTACTCACTTCAGACGCGCCGGATCTGCGTGAAGTGGAGAAAGTACGAGCTTCCCAAGAAAAAGCGTTGGCGGCGCTCCAGGCGTACATCGCGACGCATTCGCCCGGCACGCCTGCCAAGTTTGGAGAGCTGCTGTTACGCATACCCGAACTGCAGAGAACTTGCCAGTTCTTCATGCAAGTCGGAAAAGAAATGCTGAACCCAGCTAACAAAAGTAAAGATGGCGACGGACCAAGTTTCAACCTGCTCATGGAACTTTTGCGGGGCGACCACTGA
Protein Sequence: MVMSTAMNSEGEAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFNQHQYEVNMRNKKKRSSSGAHCEVSSNERERPMSWEGELSDSDMVIDTSVINDENSSSLDLQSSRDSIDTLRNVSIKTEPLKSEGFQGVDEQRVLDLKYSAPLQPHQRSLSMNRISVLTDGTSLSLARRPSSPTNSAKSLVLSDQVSALVPHAGLDQVHNLTIKKETQLSELKCEQSVGMDKLIGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVMYREAAVAYDGTHDDETDAPEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYSSRGESSNSQVTPDIPALLQEIMDVEHLWQYNESELSRLGKSTGSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPGTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_00806824;
80% Identity: iTF_00450269;