Basic Information

Gene Symbol
-
Assembly
GCA_949775195.1
Location
OX459195.1:7536734-7541179[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.008 1 11.3 1.6 3 23 89 110 88 110 0.96
2 23 0.023 2.9 9.9 0.6 1 22 504 525 504 525 0.95
3 23 6.3 7.9e+02 2.2 0.4 1 22 567 588 567 590 0.82
4 23 0.0029 0.37 12.7 4.0 2 22 600 620 599 620 0.93
5 23 0.89 1.1e+02 4.9 0.0 3 23 629 650 627 650 0.89
6 23 0.015 1.9 10.5 0.2 3 23 671 692 669 692 0.96
7 23 0.0015 0.19 13.6 1.7 1 23 698 721 698 721 0.95
8 23 0.11 13 7.8 0.0 1 23 747 770 747 770 0.90
9 23 0.035 4.4 9.3 3.3 1 23 775 797 775 797 0.97
10 23 0.0069 0.87 11.6 0.1 1 23 803 826 803 826 0.95
11 23 0.0077 0.97 11.4 1.1 1 23 839 861 839 861 0.97
12 23 0.00015 0.019 16.8 1.8 1 23 913 936 913 936 0.97
13 23 0.0011 0.14 14.1 1.3 1 23 996 1019 996 1019 0.96
14 23 0.0017 0.21 13.5 2.0 2 23 1046 1068 1045 1068 0.95
15 23 0.033 4.2 9.4 0.1 2 23 1074 1096 1073 1096 0.94
16 23 0.0083 1 11.3 0.2 1 21 1140 1160 1140 1161 0.95
17 23 0.00035 0.044 15.6 1.0 1 23 1171 1193 1171 1193 0.93
18 23 9.4e-05 0.012 17.4 0.3 2 23 1286 1308 1286 1308 0.93
19 23 3.3e-07 4.2e-05 25.1 1.4 3 23 1315 1335 1314 1335 0.98
20 23 0.018 2.3 10.2 0.3 1 23 1353 1375 1353 1376 0.95
21 23 0.15 20 7.3 0.0 1 23 1399 1421 1399 1421 0.97
22 23 0.023 2.9 9.9 0.6 1 23 1427 1450 1427 1450 0.95
23 23 0.00021 0.027 16.3 0.4 1 23 1458 1481 1458 1481 0.96

Sequence Information

Coding Sequence
ATGTTGCAATACAGCATAAATTTTGAtcatatttttgattttataagaATCTATTGTTGTTATACTTGTAACTATTTCGAATTTTATCATCAATTACAGGGTGCGGAGAGTGAGAACAATGAAGAAGACGAGGAAGAAAGTAGCGAACCCGCACAAAATTTCCCAAAAATGCCCAACATGCCCGAGGTGTCTATCACGGTCATGAGGCCTACTGGTGAGACCCTGCACGCTCGCCAAGGTATTCACCAACTCGCTTCGAAACTGTGCCTCGTCTGCGGCCGCTCGTACAGGTACTCTCACAACGCACGCAGACATGAACTTACCTCTCACAGCTTCGACAGATATACAAACAAAATTACTCCTAAAAAAACCCTCAGTCATCTACAACCCAAATTGAGACCGAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAACAAGAACATGTCATCAAAAATAATGCCCATAAACAAAGTTATAACACCACAGAAACCCATTCCAATAAAGACGTCGTCAAAGACACAAAATAATTTGCCTTATCCTCTACGCATTAAAGCactcaaagatttacaaattaaGAAGAAGGAGCCTCAGATTCTTAAGACATTATTAACCACTAAACCTGAAGTTCTGGTCTCAGAACCAGAAATTCTAAATTCTGGGCCTGAAAGTCCAGAAACATTGATATCTGAGCCTGAAATTGCATCTTTTCAAGTTGAAACTATTCTTACGGAACCGGATGCCGATGCATACGATGATCTACAGCAAGGCGACGAAGAAGTCGATGAAGAAATGCAgaacaatcaaaatcaaaactatgACACTGTCGATATGGACTCTGAGAACGAAATAGAGATTGCTCGTCAGCAAAGCAGTGAACACGACGGCGATGAAAATGCTGATGGGGACGAGAATATGGACCATGATGACGACAATAACATGGAAGGCGGTCAGAGCGATAAcgagaaagatgccaatgacgATACAGCCGACAGTCAAGAGAACATAGAAGAAGATAGTGTTGATATTAAACCTGAAGACCAAATGAAGGAAGAAGACGGCCAAGAGGAGGGAGAACACGAAGAAGAAGTAGAAATGAATCATAATGATAACGAAGAAGAAGACGATGATGACCTGCCTATGTCTATAGCGCCCGTAGTGGAAATAAGTGAGGGATTGCAAGGCGACTCGTTCAACAGCGAAGTCGTAGAGGAAGAGGACGAGCTCGACGAAACTGTCGATCCGAATGATCCCAGTGATCCCAATGATCCCAATGACACCATTCAAGAGGAAGAACAGGTTAAAGAACTTGACCCTGACAAAACGTATGTTACGAAAACCCAAAGAGACTTCATCCAAAAATTCCGTGATATCATACAGCAAATCAACACTAAACGTTGTTTATGTTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGACACAAGGTACCAAAACACACATGCTACAATTGTGTCATCACATTTAGTCATATTGGCGCACTACTCAGCCATATGAGGTCGAACTCTTGCACCAATCTGTGGAAGATTATTTACAATGAAAATGGCATTACGGACGACCAGGTTCTCGAAGATGAGCCGAAAGAAGTCAAGGTTGCTTACAAAGATATTTTCAATGCCAGGTCATATGCTTGCAAACTCTGCCCAGCTAAATTCCAACTGAAACAGTTTATAATGAAGCATGTTTTGGATACCCATGAGGATGGACAGTCAAGGATACCACTTTGTTGTGTCCACTGCCGCGCTAGATTCAAAGATAAGAGTTTACTAAAGAAACATATCCGTAAAGGGGATTGTACAGTTTATATTGCTTGCGATTTGTGCTCAGAAACGTTCGGGAACATGCAGGACTTCAACGACCATGCGCTAGCAATCCACGCCGGCAGTTTCGATCAGTCGGATAATCAAAGCAAATGTGTTGACGGTCGACCAACAGACTGTCCTTTGTGTGGAAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAGATTATACATGCTGAGGAAAAACCTCACTACTGCCAGCATTGTGACGCGAAATACGAACAAGCTGCTGATCTGAACAAGCACATTTACATGGAGCATTCTGACAGAACACTAGGCATGCCGCCTGCTGAACCGGATATGTCCATAGTGAAGGAGGAAGCTGAGGAGTACCACTACTCCTGCACGGAATGTAATGCCATATTCGAAACTGTTGATGCGTGGACTGATCACCAAGTCGCTGAACATAACCAAGTTGCCCACCACTGTGATCAGTGTGAGAGAAAATTCCTTCGTCCTTCCGAGCTAGCAGAGCACAAAAACACTCACTTGAGGGTTAAGTTTTATCCTTGTAGTGTATGTCCCAACTCTTACAGCACTCCACAGAAACTGTCTGAGCATGTGCAACAGGCACATCCAGGAGTTGGCGCGGTCGCGGCAGGAGAGTCAGAATTCTTCTGCGACATGTGTATCAGAGCATTCAAGAGTCGCCAAGCTTACTCAAATCATATGCGTATTCACTCGaaaatacctactactaacAGGAAACCGGCTCCAATCAAGGGGGAGGGGGGATTCGCACCTCAAATTATCGGGAAACCAATCAAGCAGTATCCTATGGTTCAACCAGGTTTTGTATCATTTAAATCTAATTACAACATCCCTAACGCTCCGTATTCTTGTGACATTTGTGGTAAAGGATTCATGCATAAGAAAAATATATGGAAACACAAGAAAGTGTTGCATGCCGATATTTTAGTCGATAGACATGATAGTGAAGAGAACACTATGCAAGCTTCCACTGAAGAGGATGAATTTAACCCTGATGAGAATGGTGCCATTCTCTCGACGCCacaatttaatagttttaactttATGAACTTACCGAACAATGCTCAACAACCAACACCAGAACCATTGCCATACTCGTGTGAGTTATGTAGCAAACGGTTCCCGCTTAAAAACAGTTTATGGAAACACAAGCGCGCAAAACACGGTATTGTAAACCCTAGCACTAGTGGTAACAACGATACGTCAACGCCTTCCGCCAGCGGAGAAAGCAGTAGTCGATCTAGCTGCACTATATGCAGAATATCATTTTCAGATAAGAAATCTTACTATCGCCATCGAAAGAATGTTCACAAATCTACCGTTCAAATGTGCAAAATATGTGGCAAACCGCTAAGTTCAACTTTGGAATTATACGAGCACTTGAAAGCTGCTCATGCAAGGGAGTTACTGGGGTATAACGCTAACCAAGGCTCCAGTAAATCACAAGACATGTCACTAGAGATGGAACcagattatgaaaatgatcAGGAGTCTATCGACCCCAGCGTTGATTACCAAGCGCGGTATCCATGTGATACTTGTGGCAAACAGTTTGTTGGTTTGCTAGCTTTGCAAAACCACCAGTGCATCAATCAGATATCATCACAGCCACAGACGTTTGACTGCGAGATTTGTCACAAGAGTTACACTTCAATATCTGCGCTAAAAAGCCATCGTGGGTGGCATTTACGTTCACCCGATGGAAAAGCTGCCGCCAACAATTCTGGCCTGTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGCAAACATGAGGTTGTGGACGCGTCTCAACTGGCTAAGGTCACACACACCCCCACTCCCCCACCTGTAACTGCTACCGTAGCGAAAAGAAGACTACCGCCAGAGGTCGAAGTGACAGTCGTAAACCCGAACAAGAAACTGCGCTCAGACGACTCGGTGGACTTGGATATGCAAAGTGCTGGTGCCATCGAGGATAGGTACTGTACGATTTGCGATAAGGAATTCACAAAACGAGCGGCGTACCAGCGCCACATGGACGAGGTACATCAACCGAACTCTGTGTTTTGCCCGGTTTGCGATAAGAGTTTTACAAGGAAGTCCACATTGCTCATTCACATGAAAAAACATTATGAGAGTGGTGAGGGCAGTTCTTCTGCTACAGGTCAAGGGGACGATGATTACTCCTGTGATCTGTGTGGAGCTCAGTATGACAATGATCAGGCATTGAGGGCGCACCGAGCGCGGCACCACGGAGAAGACGAAGAGTCGGCCGAAGAGAGTGACGACGGAAATGTTCCTATTGCTCCTCCCGGTGAATTCACATGTGCGCAATGTGGCGATGGCGTCGCCACTCCCAGGGACCTCATCGCCCATCGCACAATGCACGCTACTCCCACCAAATTCTTCTGTAACATATGTAAAGTGTACTTCGCTCGGGCGCTCGATCTCTCGTCGCACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGGTTTTACATGAACAAGAAGAGCTTACAGCGGCACATTGAGATGGCTCACTGA
Protein Sequence
MLQYSINFDHIFDFIRIYCCYTCNYFEFYHQLQGAESENNEEDEEESSEPAQNFPKMPNMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTSHSFDRYTNKITPKKTLSHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMSSKIMPINKVITPQKPIPIKTSSKTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTTKPEVLVSEPEILNSGPESPETLISEPEIASFQVETILTEPDADAYDDLQQGDEEVDEEMQNNQNQNYDTVDMDSENEIEIARQQSSEHDGDENADGDENMDHDDDNNMEGGQSDNEKDANDDTADSQENIEEDSVDIKPEDQMKEEDGQEEGEHEEEVEMNHNDNEEEDDDDLPMSIAPVVEISEGLQGDSFNSEVVEEEDELDETVDPNDPSDPNDPNDTIQEEEQVKELDPDKTYVTKTQRDFIQKFRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFSHIGALLSHMRSNSCTNLWKIIYNENGITDDQVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRIPLCCVHCRARFKDKSLLKKHIRKGDCTVYIACDLCSETFGNMQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAEEKPHYCQHCDAKYEQAADLNKHIYMEHSDRTLGMPPAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCERKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQAHPGVGAVAAGESEFFCDMCIRAFKSRQAYSNHMRIHSKIPTTNRKPAPIKGEGGFAPQIIGKPIKQYPMVQPGFVSFKSNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEDEFNPDENGAILSTPQFNSFNFMNLPNNAQQPTPEPLPYSCELCSKRFPLKNSLWKHKRAKHGIVNPSTSGNNDTSTPSASGESSSRSSCTICRISFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMSLEMEPDYENDQESIDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQISSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDASQLAKVTHTPTPPPVTATVAKRRLPPEVEVTVVNPNKKLRSDDSVDLDMQSAGAIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNDQALRAHRARHHGEDEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00852035;
90% Identity
iTF_00852035;
80% Identity
-